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Drug Discov Ther ; 12(6): 374-378, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30674773

RESUMO

Mucormycosis is an uncommon aggressive fungal infection usually seen in immunocompromised hosts or patients with burns and trauma. The common presentations include rhino-orbital-cerebral and pulmonary involvement. Osteoarticular involvement is a rare presentation of this disease. We present two cases of osteoarticular mucormycosis of pelvis and long bones of the lower limb, one in a patient with burn injury and other one in a patient with chronic granulomatous disease, hitherto a rarely reported association. Delayed diagnosis in a setting where tuberculosis is a common cause of chronic osteomyelitis, challenges in medical and surgical management of these patients are discussed in this report.


Assuntos
Doença Granulomatosa Crônica/microbiologia , Extremidade Inferior/microbiologia , Mucormicose/diagnóstico , Mucormicose/terapia , Ossos Pélvicos/microbiologia , Adulto , Amputação Cirúrgica , Antifúngicos/uso terapêutico , Queimaduras/microbiologia , Queimaduras/cirurgia , Desbridamento/efeitos adversos , Gerenciamento Clínico , Humanos , Extremidade Inferior/cirurgia , Masculino , Mucormicose/etiologia , Ossos Pélvicos/cirurgia , Adulto Jovem
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