[Role of peptide complexes from the kidney and thymus in the regulation of apoptosis in lymphoid cells]. / Rol' peptidnykh kompleksov pochek i timusa v reguliatsii apoptoza limfoidnykh kletok.

Using morphological and electrophoresis methods special features of apoptosis induction by peptide complexes from kidney and thymus were analyzed in thymocytes and peripheral blood lymphocytes of pigs. It was shown that peptide complexes both from kidney and thymus induced thymocytes apoptosis in an allogenic system. In these conditions, genetic distinctions between individuals and a degree of thymocyte maturation determined the level of apoptosis.

[Apoptosis in the cells of parenchymatous organs in subacute sodium nitrate poisoning]. / Apoptoz v kletkakh parenkhimatoznykh organov pri podostroi intoksikatsii nitratom natriia.

Subacute intoxication was induced by the oral administration of sodium nitrate 200 mg/kg during 150 days to Wistar rats. After the time had been up severe damaging were found in liver, kidney, heart and thymic tissues. In the liver cells the DNA fragmentation in "scale" manner was found, but not in kidney and heart cells. Simultaneously, the Ca2+, Mg(2+)-depended endonucleases activity were increased in the liver nuclei extracts under intoxication. It was suggested that increasing of apoptosis in liver is the universal reaction to toxins.