RESUMO
Results of investigation of collagen metabolism in Dupuitren's contracture (DC) were summarized. The patients were operated for calculous cholecystitis and DC stages II - III. The changes revealed witnessed about more expressed degradation of collagen and affection of the elastin components of connective tissue. On background of the pathological process progress in palmar aponeurosis in patients, suffering DC, a content of oxyproline have enhanced trustworthy in urine and reduced in tissue of a changed palmar aponeurosis.
Assuntos
Colecistite/metabolismo , Colágeno/metabolismo , Contratura de Dupuytren/metabolismo , Fáscia/metabolismo , Hidroxiprolina/urina , Cirrose Hepática/metabolismo , Idoso , Aminoácidos/sangue , Colecistite/complicações , Colecistite/cirurgia , Tecido Conjuntivo/metabolismo , Contratura de Dupuytren/complicações , Contratura de Dupuytren/cirurgia , Elastina/metabolismo , Humanos , Cirrose Hepática/complicações , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de DoençaRESUMO
The results of morphological investigation of hepatic tissues in 98 patients, suffering contracture of Dupuytren, chronic hepatitis and hepatic fibrosis stages I, II i III, were adduced. The patients were operated on for calculous cholecystitis. The attempt to organize the groups with certain morphological changes, depending on the hepatic pathological process persistence (up to 5 yrs, from 5 to 10 yrs, over 10 yrs) have appeared nonfair. The changes revealed are too different and characteristic not only for the examined patients.
Assuntos
Contratura de Dupuytren/patologia , Hepatite Crônica/patologia , Fígado/patologia , Idoso , Colecistite/complicações , Colecistite/patologia , Colecistite/cirurgia , Contratura de Dupuytren/complicações , Vesícula Biliar/patologia , Vesícula Biliar/cirurgia , Hepatite Crônica/complicações , Hepatócitos/patologia , Histocitoquímica , Humanos , Cirrose Hepática/complicações , Cirrose Hepática/patologia , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de DoençaRESUMO
Dupuytren's contracture--a pathology that should not be seen as an isolated lesion tendon-aponeurotic structures of the palmar surface of the hand, but as a disease that requires careful research and a comprehensive, differentiated approach to treatment. The aim of the study was to investigate the functional activity of the phagocytic system of Dupuytren's contracture patients with chronic hepatitis and liver fibrosis in liquidators of the CHNPP accident consequences. The resulting study 188 patients aged 45-65 years showed the correlation of the data of the functional activity of phagocytic system with degree of liver fibrosis, thus objectively assess the patient's condition and make the appropriate correction in the diagnostic criteria as well as in medical and rehabilitative programs.