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1.
J Small Anim Pract ; 64(4): 296-305, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36573276

RESUMO

OBJECTIVES: The aim of this case series was to collect preliminary data on safety and efficacy of treating cats suffering from refractory feline chronic gingivostomatitis with a single intravenous therapy of cryopreserved placenta-derived mesenchymal stromal cells. MATERIALS AND METHODS: We planned the prospective inclusion of cats suffering from refractory chronic gingivostomatitis in three veterinary clinics. All cats received a single infusion of 10×106 cryopreserved cells. Follow-up evaluations were done at day 15 and at 2-, 3- and 6-months following infusion. Clinical disease severity was evaluated by dental specialists using a published stomatitis disease activity index scoring system coupled with an owners' assessment questionnaire. RESULTS: All eight cats attended all follow up visits. Cryopreserved ready-to-use placenta-derived cells administered systemically were safe and resulted in notable clinical improvement in all cats as reported by stomatitis disease activity index scoring and owner's survey. CLINICAL SIGNIFICANCE: Infusion of cryopreserved freshly thawed placenta-derived mesenchymal stromal cells appears to promote clinical and consequently behavioural benefits in cats with refractory chronic gingivostomatitis after having undergone full-mouth or premolar-molar tooth extraction. Future randomised studies are required to confirm safety and efficacy of this treatment.


Assuntos
Doenças do Gato , Células-Tronco Mesenquimais , Estomatite , Gatos , Animais , Estudos Prospectivos , Estomatite/tratamento farmacológico , Estomatite/veterinária , Doenças do Gato/terapia
2.
Reprod Domest Anim ; 52(6): 1025-1029, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28695674

RESUMO

The goal of this study was to evaluate the reliability of amniocentesis during late pregnancy to assess lung maturity in puppies using a bubble test as described by Gunston and Davey (South African Medical Journal, 54, 1978, 495). Thirty-five bitches from eight different breeds were followed during late pregnancy before undergoing elective Caesarean (C)-section on days 61-62 after ovulation. Bubble tests were performed the day before the C-section (n = 11 bitches) and before the administration of aglepristone on amniotic fluid samples obtained via amniocentesis and were repeated the day of the surgery on amniotic fluid samples collected via puncture of the amniotic bags before they were opened (n = 35 bitches). No complications were observed following amniocenteses and the C-sections. The mortality rate (2.3%) was similar to the result of other studies using the same protocol for an elective C-section. Of the non-contaminated samples collected the day of the C-section, 89.6% were positive in the bubble test, which was consistent with observations of clinical maturity the day of the surgery and on the following days. In contrast, 70% of the samples collected the day before the C-section (when progesterone concentrations were still high) were negative, suggesting that the puppies were still immature at this point in the pregnancy. Additionally, we observed a significant difference in the bubble test results before and 18 hr after the administration of aglepristone, suggesting that aglepristone may act as an inducer of the final maturation of the puppies by inactivating progesterone receptors and simulating a physiological decrease in progesterone. Finally, we confirmed the need to exclude all contaminated samples, which could lead to false-negative results.


Assuntos
Líquido Amniótico , Cães , Desenvolvimento Fetal , Amniocentese , Animais , Animais Recém-Nascidos , Cesárea/veterinária , Estrenos/administração & dosagem , Estrenos/farmacologia , Feminino , Pulmão/embriologia , Gravidez , Progesterona/metabolismo , Reprodutibilidade dos Testes
3.
Eur J Vasc Endovasc Surg ; 51(5): 641-6, 2016 05.
Artigo em Inglês | MEDLINE | ID: mdl-26879098

RESUMO

OBJECTIVE: During endovascular repair of abdominal aortic aneurysms (EVAR), in the absence of a distal iliac landing zone, the Amplatzer plug is increasingly being used to replace other internal iliac artery (IIA) embolization techniques. This study aimed at assessing the technical success, complication occurrence, and durability of the Amplatzer plug for IIA embolization. METHOD: From January 1, 2007 to December 31, 2013, all consecutive patients who underwent internal iliac embolization with an Amplatzer plug during EVAR were included in the study. There were 169 patients, (160 men, 9 women, mean 75 ± 9 years), treated by unilateral (158 cases, 93%) or bilateral (11 cases, 7%) embolization of the IIA, performed either separately prior to (65 cases, 38.5%) or during EVAR (104 cases, 61.5%). Follow up CT scan and/or US scan were performed 1 month after treatment and yearly thereafter. The inclusions were done retrospectively but the series was continuous and consecutive. Data were collected and analyzed using acquisition REDCap software. RESULTS: The technical success rate was 97.6%. Failures were device migration (n = 1), navigation failure (n = 2), and release outside the target zone (n = 1). On average, 1.43 plugs were required to achieve the embolization. The average amount of contrast agent for the embolization procedure was 111 ± 51 mL and the radiation dose was 127,777 ± 89,528 mGy/cm(2). The total fluoroscopy time was 854 ± 538 seconds. No re-canalization of the IIA trunk was observed during follow up. Complications were buttock claudication (n = 41, 24.3%), which resolved in 24 cases (58.5%, 24/41) at the first follow up, and intestinal ischemia requiring limited bowel resection in two cases. CONCLUSION: This multicenter study is the largest published to date. It demonstrates the efficacy and reliability of the Amplatzer plug to embolize the IIA during EVAR, with few side effects.


Assuntos
Aneurisma da Aorta Abdominal/cirurgia , Implante de Prótese Vascular , Artéria Ilíaca/cirurgia , Idoso , Aneurisma da Aorta Abdominal/terapia , Implante de Prótese Vascular/efeitos adversos , Implante de Prótese Vascular/instrumentação , Implante de Prótese Vascular/métodos , Procedimentos Endovasculares/métodos , Feminino , Humanos , Masculino
5.
Eur J Vasc Endovasc Surg ; 47(5): 470-8, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24656593

RESUMO

OBJECTIVES: The aim of this study was to assess the results of hybrid techniques for the treatment of thoracic, thoracoabdominal, and abdominal aortic aneurysms based on multicenter results and the various series regarding hybrid procedures reported in the literature. METHODS: The results of 76 hybrid procedures performed in 19 French university hospital centers between November 2001 and October 2011 were collected. There were 50 men and 26 women, mean age 68.2 (35-86) years. All patients were considered at high risk (ASA≥3) for conventional surgery. Aneurysms involved the thoracic, abdominal, and thoracoabdominal aorta in five, 14, and 57 cases respectively. There were 11 emergent repairs. The revascularization of four visceral arteries was performed in 38 cases. Between one and three visceral arteries were revascularized in the other cases. Visceral artery debranching and stent graft deployment were performed in a one-stage procedure in 53 cases and in a two-stage procedure in 23 cases. RESULTS: There were 26 (34.2%) postoperative deaths. Nine of the survivors developed paraplegia, of which one resolved completely. Bowel ischemia occurred in 13 cases (17.1%), and one patient was treated by a superior mesenteric artery bypass. Four patients required long-term hemodialysis. Postoperative computed tomography scan showed a type II endoleak in two patients. CONCLUSIONS: Morbidity and mortality in this study were greater than previously reported. Candidates for hybrid aortic repair should be carefully selected.


Assuntos
Aneurisma da Aorta Abdominal/cirurgia , Aneurisma da Aorta Torácica/cirurgia , Prótese Vascular , Procedimentos Cirúrgicos Vasculares/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia , Aneurisma da Aorta Abdominal/diagnóstico , Aneurisma da Aorta Abdominal/epidemiologia , Aneurisma da Aorta Torácica/diagnóstico , Aneurisma da Aorta Torácica/epidemiologia , Feminino , França/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Morbidade/tendências , Estudos Retrospectivos , Taxa de Sobrevida/tendências , Tomografia Computadorizada por Raios X , Resultado do Tratamento
6.
J Mal Vasc ; 38(3): 162-71, 2013 May.
Artigo em Francês | MEDLINE | ID: mdl-23473620

RESUMO

PURPOSE: Lymphoma is a polymorphous disease that does not spare arteries. Arterial involvement may be perivascular or intravascular, with different prognostic and therapeutic implications. PATIENTS AND METHODS: We present here one case of perivascular lymphoma and another case of intravascular lymphoma in order to highlight the specific features of each type. RESULTS: The first patient was a woman who presented a pseudo-aneurysmal anterior iliac artery due to a non-Hodgkin lymphoma with subsequent bilateral pyelocalyceal distension. The second patient was a man who developed intravascular lymphomatosis expressed by an aneurysm of the common femoral then the primitive iliac artery. CONCLUSION: The distinction between perivascular and intravascular arterial involvement is based on a range of features and is essential for an optimal care of patients with lymphoma.


Assuntos
Artéria Femoral/patologia , Artéria Ilíaca/patologia , Linfoma Difuso de Grandes Células B/patologia , Idoso , Aneurisma/etiologia , Aneurisma/patologia , Falso Aneurisma/etiologia , Falso Aneurisma/patologia , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Aorta Abdominal/patologia , Arteriopatias Oclusivas/etiologia , Arterite/diagnóstico , Diagnóstico Diferencial , Feminino , Quarto Ventrículo/patologia , Humanos , Hidrocefalia/etiologia , Linfoma Difuso de Grandes Células B/complicações , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/diagnóstico por imagem , Linfoma Difuso de Grandes Células B/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons , Recidiva , Obstrução da Artéria Renal/complicações , Sarcoma/diagnóstico , Trombose/etiologia
7.
Eur J Vasc Endovasc Surg ; 45(1): 22-7, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23116990

RESUMO

OBJECTIVES: There is no standardised technique for internal iliac artery aneurysm (IIAA) embolisation and results of long-term prevention of rupture are unknown. DESIGN: We retrospectively evaluated technical aspects and results of IIAA embolisation in a multicentre study. METHODS: Aneurysm morphology and embolisation techniques were reviewed. Aneurysm-related death, rupture, diameter increase, endoleak, secondary procedure and complication related to the IIA occlusion were recorded. RESULTS: Between 2001 and 2011, 53 patients with 57 IIAA were treated. Mean diameter of IIAA was 41 mm (range: 25-88 mm). Embolisation techniques were distal and proximal occlusion (n = 24), proximal occlusion (n = 18) and sac packing (n = 15). Cumulative overall survival rate was 92% at 1 year, 83% at 3 years and 59% at 5 years. No cause of deaths was related to aneurysm. Aneurysm diameter increased in five patients and endoleak was observed in 11 patients. One secondary open conversion and five secondary endovascular procedures were performed for increase of diameter or proximal endoleak. Two patients experienced a disabling buttock claudication. CONCLUSIONS: Embolisation of IIAA is safe in the short- and midterm. However, endoleak and aneurysm diameter increases are not rare. Yearly post-procedure computed tomography angiography seems appropriate.


Assuntos
Embolização Terapêutica , Aneurisma Ilíaco/terapia , Artéria Ilíaca/patologia , Idoso , Idoso de 80 Anos ou mais , Aneurisma da Aorta Abdominal/complicações , Aneurisma da Aorta Abdominal/cirurgia , Implante de Prótese Vascular/efeitos adversos , Nádegas/irrigação sanguínea , Dilatação Patológica , Embolização Terapêutica/efeitos adversos , Embolização Terapêutica/mortalidade , Endoleak/etiologia , Procedimentos Endovasculares/efeitos adversos , Feminino , França , Humanos , Aneurisma Ilíaco/complicações , Aneurisma Ilíaco/diagnóstico , Aneurisma Ilíaco/mortalidade , Artéria Ilíaca/diagnóstico por imagem , Claudicação Intermitente/etiologia , Isquemia/etiologia , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Retrospectivos , Fatores de Tempo , Tomografia Computadorizada por Raios X , Resultado do Tratamento
8.
Eur J Vasc Endovasc Surg ; 22(2): 169-74, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11472053

RESUMO

OBJECTIVE: to propose an anatomical classification of juxtarenal aortic aneurysm (JRA) that relates to their epidemiology and the result of surgical repair. MATERIAL AND METHODS: retrospective study of 53 JRA and 376 infrarenal aortic aneurysm (AAA) operated between January 1989 and August 1999. RESULTS: perioperative mortality after JRA repair was 19% for type A (interrenal), 13% for type B (aneurysm of one or two renal origins) and 4% for type C (no infrarenal neck). These differences were not significant. The overall perioperative mortality after JRA repair (11%) was significantly higher than mortality of AAA (3%p<0.01). Postoperative morbidity after JRA repair was 62% for type A, 75% for type B and 33% for type C. Postoperative morbidity after type B repair was significantly more frequent than after type C (p<0.001). The overall postoperative morbidity (51%) was significantly more frequent than after AAA repair (26%p<0.01). Preoperative ischaemic heart disease, aortic clamping above the coeliac axis and aortic proximal clamping longer than 30 min were significant risk factors for death after JRA repair. Survival by life-table analysis at five years after JRA repair and AAA repair were respectively 73%+/-7% and 76%+/-3%. CONCLUSION: there is a less favourable outcome after JRA repair as compared to AAA repair. The complexity of the surgical procedure requires accurate preoperative morphological assessment. The proposed classification of juxtarenal aneurysms may be helpful in guiding surgical access.


Assuntos
Aneurisma da Aorta Abdominal/classificação , Adulto , Idoso , Idoso de 80 Anos ou mais , Aneurisma da Aorta Abdominal/mortalidade , Aneurisma da Aorta Abdominal/cirurgia , Feminino , Humanos , Rim , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/mortalidade , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Taxa de Sobrevida , Resultado do Tratamento
9.
Ann Vasc Surg ; 15(2): 140-7, 2001 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11265076

RESUMO

The purpose of this study was to evaluate the early and mid-term results of endovascular treatment of occlusive lesions in the distal aorta in a consecutive series of patients. Between February 1996 and March 1999, a total of 31 patients underwent transluminal procedures for treatment of occlusive atherosclerotic lesions located at the lower end of the aorta. Thirty patients presented with intermittent claudication and one had critical ischemia. Manifestations were bilateral in 26 cases and unilateral in 5. The lesion was confined to the lower aorta in 3 patients and extended to the common iliac arteries in 19, with predominant proximal lesions of the common iliac artery occurring in 9 patients. Fourteen patients had concurrent infracrural occlusive lesions. All patients underwent exclusive endovascular treatment without any associated open surgical procedure. The three patients with isolated aortic lesions were treated by angioplasty, followed by stent placement in two cases. The 19 patients with aortobiiliac lesions were treated by bilateral common iliac artery angioplasty according to the "kissing-balloon" technique; 7 of these patients also underwent aortic angioplasty. In these 19 patients, aortic stenting was performed in 3 cases and bilateral iliac stenting in 10 cases, including 3 in association with aortic stenting. The nine patients with a proximal lesion of the common iliac arteries were treated by angioplasty, followed by bilateral stenting in three cases and unilateral stenting in three cases. The findings of this study show that the mid-term anatomical and functional results of endovascular treatment for atherosclerotic lesions of the distal aorta are satisfactory. We recommend it as the initial treatment modality.


Assuntos
Angioplastia com Balão , Aorta Abdominal , Doenças da Aorta/terapia , Arteriopatias Oclusivas/terapia , Isquemia/terapia , Stents , Adulto , Idoso , Idoso de 80 Anos ou mais , Aorta Abdominal/diagnóstico por imagem , Doenças da Aorta/diagnóstico por imagem , Aortografia , Arteriopatias Oclusivas/diagnóstico por imagem , Arteriosclerose/diagnóstico por imagem , Arteriosclerose/terapia , Feminino , Seguimentos , Humanos , Claudicação Intermitente/diagnóstico por imagem , Claudicação Intermitente/terapia , Isquemia/diagnóstico por imagem , Perna (Membro)/irrigação sanguínea , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
10.
Ann Vasc Surg ; 15(2): 219-26, 2001 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11265087

RESUMO

The purpose of this study was to demonstrate that severe multipedicular lesions involving supraaortic trunks cause compromised cerebral hemodynamics with nonhemispheric symptoms (NHS) that can be relieved by surgical treatment. A total of 11 patients were prospectively included in the study. Regional cerebral blood flow (rCBF) and cerebral blood flow reactivity (CBFR) were measured by acetazolamide single photon emission computed tomoscintigraphy scans (SPECT) before and after surgery. Seven patients presented with isolated NHS and four presented with NHS associated with hemispheric symptoms. Lesions consisted of either high-grade (>75%) bilateral carotid artery stenosis associated with vertebral or subclavian artery lesions or high-grade (>75%) bilateral vertebral or subclavian artery stenosis associated with medium-grade (>50%) carotid lesions. All patients presented with a functional circle of Willis with no significant intracranial arterial lesions and no corticosubcortical atrophy. A total of 15 procedures were performed for revascularization of 19 arteries. The cumulative morbidity/mortality rate was nil. All revascularizations were patent on postoperative controls. Results from this study show that multipedicular lesions lead to hemodynamic changes affecting hemispheric and vertebrobasilar territories. Surgical treatment can improve or normalize cerebral hemodynamic abnormalities and relieve NHS.


Assuntos
Isquemia Encefálica/diagnóstico , Doenças Arteriais Cerebrais/diagnóstico , Hemodinâmica/fisiologia , Idoso , Idoso de 80 Anos ou mais , Encéfalo/irrigação sanguínea , Isquemia Encefálica/fisiopatologia , Isquemia Encefálica/cirurgia , Doenças Arteriais Cerebrais/fisiopatologia , Doenças Arteriais Cerebrais/cirurgia , Revascularização Cerebral , Diagnóstico Diferencial , Dominância Cerebral/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Fluxo Sanguíneo Regional/fisiologia , Tomografia Computadorizada de Emissão de Fóton Único
11.
Ann Vasc Surg ; 14(6): 567-76, 2000 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11128450

RESUMO

The aim of this retrospective study was to substantiate our results of lower limb revascularizations from the descending thoracic aorta. From November 1984 to November 1994, we used bypass grafting from the descending thoracic aorta to revascularize 69 lower limbs in 36 patients, 34 men and 2 women, whose mean age was 61.8 years. Patients were divided into two groups. Group I (primary indications) included 10 patients who had not had any prior lower limb arterial reconstruction. Group II (secondary indications) consisted of 26 patients who had had a prior arterial reconstruction that was either occluded or complicated. There were three early graft occlusions, all of them successfully treated. Complete flaccid, paraplegia occurred in one patient. Five patients presented with one or several late graft occlusions. Two patients had to undergo below-knee amputation, bilateral in one patient. Routine late control of the repair was performed by CT scanning, at a mean interval of 50.8 months. The good results recorded for bypasses revascularizing lower limbs from the descending thoracic aorta make this technique a satisfactory alternative when the abdominal aorta cannot be used.


Assuntos
Aorta Torácica/cirurgia , Implante de Prótese Vascular , Isquemia/cirurgia , Perna (Membro)/irrigação sanguínea , Adulto , Idoso , Aorta Torácica/diagnóstico por imagem , Feminino , Seguimentos , Oclusão de Enxerto Vascular/diagnóstico por imagem , Oclusão de Enxerto Vascular/cirurgia , Humanos , Isquemia/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Reoperação , Estudos Retrospectivos , Tomografia Computadorizada por Raios X
12.
J Vasc Surg ; 31(4): 713-23, 2000 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-10753279

RESUMO

PURPOSE: Extracranial internal carotid artery aneurysms (EICAs) can be treated by carotid ligation or surgical reconstruction. In the consideration of the risk of stroke after internal carotid artery (ICA) occlusion, the aim of this study was to report the results of reconstructive surgery for these aneurysms, including lesions located at the base of the skull. METHODS: From 1980 to 1997, 25 ICA reconstructions were performed for EICA: 22 male patients and 3 female patients (mean age, 54.4 years). The cause was atherosclerosis (n = nine patients), dysplasia (n = 12 patients), trauma (n = three patients), and undetermined (n = one patient). The symptoms were focal in 15 cases (12 hemispheric, three ocular), nonfocal in three cases (trouble with balance and visual blurring), and glossopharyngeal nerve compression in one case. Six cases were asymptomatic, including three cases that were diagnosed during surveillance after ICA dissection. In nine cases, the upper limit of the EICA reached the base of the skull. A combined approach with an ear, nose, and throat surgeon allowed exposure and control of the ICA. RESULTS: After operation, there were no deaths, one temporary stroke, two transient ischemic attacks, and 11 cranial nerve palsies (one with sequelae). The ICA was patent on the postoperative angiogram in all but one case. During follow-up (mean, 66 months), there were two deaths (myocardial infarction), one occurrence of focal epileptic seizure at 2 months, and one transient ischemic attack at 2 years. In December 1998, duplex scanning showed patency of the reconstructed ICA in all but one surviving patient. CONCLUSION: Surgical reconstruction is a satisfactory therapeutic choice for EICA, even when located at the base of the skull.


Assuntos
Aneurisma/cirurgia , Doenças das Artérias Carótidas/cirurgia , Artéria Carótida Interna/cirurgia , Adolescente , Adulto , Idoso , Aneurisma/etiologia , Aneurisma/fisiopatologia , Angiografia , Doenças das Artérias Carótidas/complicações , Doenças das Artérias Carótidas/etiologia , Doenças das Artérias Carótidas/fisiopatologia , Lesões das Artérias Carótidas/complicações , Dissecação da Artéria Carótida Interna/complicações , Causas de Morte , Epilepsias Parciais/etiologia , Feminino , Seguimentos , Nervo Glossofaríngeo/fisiopatologia , Traumatismos do Nervo Glossofaríngeo , Humanos , Ataque Isquêmico Transitório/etiologia , Ligadura , Masculino , Pessoa de Meia-Idade , Síndromes de Compressão Nervosa/fisiopatologia , Paralisia/etiologia , Complicações Pós-Operatórias , Fatores de Risco , Base do Crânio/irrigação sanguínea , Acidente Vascular Cerebral/etiologia , Resultado do Tratamento , Grau de Desobstrução Vascular
13.
Ann Vasc Surg ; 12(6): 572-8, 1998 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-9841688

RESUMO

The purpose of this retrospective study was to determine whether patients who undergo prophylactic surgery for asymptomatic carotid stenosis represent a single homogeneous population. Of the 805 carotid reconstructions performed between January 1984 and December 1992, a total of 357 were for asymptomatic atherosclerotic stenosis in 312 patients (227 men, 85 women) with a mean age of 69.6 years. Patients were divided into three groups. Group I included 141 patients (161 procedures) who presented no neurologic manifestations. Group II included 49 patients (55 procedures) who underwent carotid reconstruction before or at the same time as another cardiovascular procedure. Group III included 122 patients (141 procedures) who presented nonhemispheric manifestations. Patients in group III had a significantly higher number of obstructive lesions in brain arteries (p < 0.01). Seven patients died within the first 30 postoperative days, including three who underwent combined single-stage procedures. Nine patients presented nonfatal stroke, including three who progressively recovered. The cumulative death-stroke rate (CDSR) was 5.12% overall, 3.54% in group I, 12.24% in group II, and 4.09% in group III. The difference between groups I and II was statistically significant (p < 0.05). Taking into account only deaths related to carotid surgery and stroke with permanent disability, the CDSR was 2. 83% in group I and 3.25% in group III. Follow-up ranged from 24 to 132 months (mean: 66.2) with a total of 11 patients being lost from follow-up. Actuarial 5-year survival was 81.99 +/- 7.13% in group I, 70.65 +/- 13.72% in group II, and 68.51 +/- 8.93% in group III. Differences between group I and both groups II (p < 0.01) and III (p < 0.05) were statistically significant. Overall 5-year patency was 95.59 +/- 2.28%. Stroke occurred during follow-up in 13 patients. The probability of stroke-free survival was 95.29 +/- 3.76% in group I, 91.03 +/- 8.52% in group II, and 89.09 +/- 6.39% in group III. The difference between groups I and III was statistically significant (p < 0.05). Patients with asymptomatic carotid lesions can be divided into different prognostic groups. Life expectancy is shorter for patients with multiple artery disease. Long-term stroke risk is higher in patients with nonhemispheric neurological manifestations.


Assuntos
Estenose das Carótidas/cirurgia , Endarterectomia das Carótidas , Arteriosclerose Intracraniana/cirurgia , Análise Atuarial , Idoso , Estenose das Carótidas/complicações , Estenose das Carótidas/mortalidade , Estudos de Casos e Controles , Transtornos Cerebrovasculares/mortalidade , Transtornos Cerebrovasculares/prevenção & controle , Endarterectomia das Carótidas/mortalidade , Feminino , Seguimentos , Humanos , Arteriosclerose Intracraniana/complicações , Arteriosclerose Intracraniana/mortalidade , Expectativa de Vida , Masculino , Complicações Pós-Operatórias/mortalidade , Fatores de Risco , Fatores de Tempo
14.
J Vasc Surg ; 26(2): 238-46, 1997 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-9279310

RESUMO

PURPOSE: The aim of this study was to seek a relationship between the morphologic features of abdominal aortic aneurysms and the feasibility of endoaortic grafting. METHODS: Between June 1995 and January 1996, 86 patients were prospectively studied with contrast-enhanced spiral computed tomographic scans, which provided 35 parameters concerning the aorta and iliac arteries. Four groups were established according to the diameter of abdominal aortic aneurysms: group A, 40 to 49 mm, 36 patients; group B, 50 to 59 mm, 26 patients; group C, 60 to 69 mm, 10 patients; and group D, greater than 70 mm, 14 patients. RESULTS: There was a correlation between the diameter and length of the aneurysm (p < 0.0001) and between aneurysm diameter and length of the proximal neck (p < 0.001). Presence of a proximal neck or a distal neck was more frequent in groups A and B than in groups C and D (p < 0.01). The feasibility of endovascular grafting was estimated at between 50% and 61.6% and was higher in groups A and B than in groups C and D (p < 0.01). CONCLUSIONS: This study has shown an inverse relationship between the diameter of the aneurysm and the length of the aortic neck (correlation coefficient, -0.3640, p < 0.001). The diameter of an aneurysm was the most useful of the 31 parameters measured in predicting the feasibility of endoaortic grafting, estimated at 71% for aneurysms less than 60 mm in diameter and 37.5% for aneurysms greater than 60 mm in diameter (p < 0.01).


Assuntos
Aneurisma da Aorta Abdominal/diagnóstico por imagem , Aneurisma da Aorta Abdominal/patologia , Prótese Vascular , Tomografia Computadorizada por Raios X/métodos , Idoso , Idoso de 80 Anos ou mais , Aneurisma da Aorta Abdominal/cirurgia , Estudos de Viabilidade , Feminino , Humanos , Aneurisma Ilíaco/diagnóstico por imagem , Aneurisma Ilíaco/patologia , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos
15.
Hepatogastroenterology ; 44(14): 458-66, 1997.
Artigo em Inglês | MEDLINE | ID: mdl-9164519

RESUMO

BACKGROUND/AIMS: To evaluate the reliability of stapled esophagojejunostomy. MATERIAL AND METHODS: We studied a non-selected prospective series of 176 consecutive total gastrectomies (169 cancers, 7 benign pathologies). RESULTS: Hand-sewn esophagojejunostomy was performed 5 times after failure of the stapled esophagojejunostomy. There were fourteen hospital deaths (8%), and 63 patients (36%) presented complications. There were 5 anastomotic leaks (2.8%) but non were responsible for deaths. In these 5 cases, there had been an incident during construction of the esophagojejunostomy. Such an incident was the only significant risk factor for an anastomotic leak: 17% after an incident and 0% in the absence of an incident (p < 0.001). We observed no cases of anastomotic stricture. CONCLUSION: Stapled esophagojejunostomy is a reliable technique when technical precautions are taken. It is easier to reproduce than hand-sewn esophagojejunostomy and has demonstrated low specific morbidity and no direct mortality.


Assuntos
Anastomose Cirúrgica/métodos , Esôfago/cirurgia , Jejuno/cirurgia , Grampeamento Cirúrgico , Adulto , Idoso , Idoso de 80 Anos ou mais , Anastomose em-Y de Roux , Anastomose Cirúrgica/efeitos adversos , Anastomose Cirúrgica/instrumentação , Estudos de Viabilidade , Feminino , Gastrectomia , Humanos , Complicações Intraoperatórias , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes , Fatores de Risco , Gastropatias/cirurgia , Neoplasias Gástricas/cirurgia , Grampeamento Cirúrgico/efeitos adversos , Grampeamento Cirúrgico/instrumentação , Grampeamento Cirúrgico/métodos , Taxa de Sobrevida , Falha de Tratamento
16.
Eur J Vasc Endovasc Surg ; 12(1): 26-30, 1996 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-8696892

RESUMO

OBJECTIVE: Venous grafting is rarely employed for carotid reconstruction; the aim of this retrospective study was to assess its value as an alternative to endarterectomy. MATERIAL: Between January 1980 and June 1990, we performed 212 carotid artery venous bypasses (CVB) on 208 patients. Twenty-nine patients were asymptomatic, 60 had non-hemispheric symptoms and 119 focal symptoms. The indication for surgery was stenosis in 185 cases, kinking in 18 and aneurysms in nine. The main criteria to use CVB were length of the lesion in 86 cases, extent of atherosclerosis in 75, dysplasia in 12, intraoperative failure of endarterectomy in 21, aneurysms in seven and long-term restenosis or occlusion in 12. RESULTS: There were 11 deaths, three strokes and nine transient ischaemic attacks. Angiographic control showed one occlusion giving an immediate patency rate of 99.5%. Mean follow-up was 104.3 +/- 46.1 months with 15 patients lost to follow-up. Eighty patients died; life expectancy was 52.4 +/- 7.5 at 10 years. Including occlusions and restenosis as failures, the secondary patency rate was 96.4 +/- 3.7 at 10 years. The annual stroke rate was 1.3% and the neurologic event-free-population 87 +/- 2.4% at 10 years. CONCLUSION: CVB is a valuable alternative to endarterectomy for reconstruction of the carotid artery. The indications are extensive atherosclerosis involving the common carotid artery, intraoperative anatomic failure of endarterectomy, and long-term restenosis.


Assuntos
Doenças das Artérias Carótidas/cirurgia , Veia Safena/transplante , Adulto , Idoso , Idoso de 80 Anos ou mais , Aneurisma/cirurgia , Arteriosclerose/cirurgia , Doenças das Artérias Carótidas/diagnóstico por imagem , Artéria Carótida Interna/diagnóstico por imagem , Artéria Carótida Interna/cirurgia , Estenose das Carótidas/cirurgia , Transtornos Cerebrovasculares/etiologia , Endarterectomia das Carótidas , Feminino , Seguimentos , Humanos , Complicações Intraoperatórias/cirurgia , Ataque Isquêmico Transitório/etiologia , Expectativa de Vida , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Radiografia , Recidiva , Estudos Retrospectivos , Veia Safena/diagnóstico por imagem , Taxa de Sobrevida , Falha de Tratamento , Grau de Desobstrução Vascular
17.
Ann Vasc Surg ; 10(3): 262-72, 1996 May.
Artigo em Inglês | MEDLINE | ID: mdl-8792995

RESUMO

The purpose of this study was to use our newly developed mock circulation loop to determine the effects of cryopreservation on the common carotid artery (CCA) and the superficial femoral artery (SFA). Fourteen healthy arteries (7 CCA and 7 SFA) harvested from multiple organ donors between the ages of 18 and 35 years were tested before and after cryopreservation at -140 degrees C using dimethyl sulfoxide and the vapor phase of liquid nitrogen. Mean storage time was 4.2 months. The mock pulse rate was 60 beats/min and the following four systolic/diastolic pressures settings were used: 50/110, 80/140, 110/170, and 140/200 mm Hg. Simultaneous measurements of intra-arterial pressure and external arterial diameter were made using an intra-arterial pressure sensor and external piezoelectric sensors. Measured data were used to calculate pulsatility, volumetric compliance, stiffness, midwall radial arterial stress, Young's modulus, and the incremental modulus. After SFA cryopreservation, no significant changes were observed. Conversely, CCA cryopreservation led to a significant decrease in compliance and pulsatility and a significant increase in stiffness. Young's modulus, the incremental modulus, and midwall radial arterial stress did not change significantly. A clearcut decrease in hysteresis was observed after cryopreservation in the CCA. No evidence of structural changes was detected on light and scanning electron microscopy. Baseline findings in this study were consistent with classification of the CCA as an elastic artery and the SFA as a muscular artery. Cryopreservation had no effect on the viscoelastic properties of muscular arteries (SFA). Cryopreservation affected only values related to the cylindrical shape of the elastic arteries (CCA). It had no effect on values related to wall structure.


Assuntos
Artéria Carótida Primitiva , Criopreservação , Artéria Femoral , Adulto , Pressão Sanguínea , Artéria Carótida Primitiva/fisiologia , Artéria Carótida Primitiva/ultraestrutura , Elasticidade , Artéria Femoral/fisiologia , Artéria Femoral/ultraestrutura , Humanos , Microscopia Eletrônica de Varredura , Modelos Cardiovasculares , Pulso Arterial , Estresse Mecânico , Resistência Vascular/fisiologia , Viscosidade
18.
Spine (Phila Pa 1976) ; 21(6): 685-90, 1996 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-8882689

RESUMO

STUDY DESIGN: This retrospective study analyzed clinical and radiologic follow-up evaluations of cervical arthrodesis where interbody xenograft combined with internal fixation was used for management of post-traumatic discoligamentous instability. OBJECTIVES: To report results of use of xenograft to avoid the various disadvantages linked to the use of autologous or allogenous bone graft. SUMMARY OF BACKGROUND DATA: Ligamentous instability of the cervical spine is unlikely to heal in a high proportion of cases, and surgical arthrodesis is usually indicated. Anterior arthrodesis has proved to be a safe procedure, but many problems are associated with the use of autograft or allograft. Given the great number of xenograft procedures, there are relatively few reports in the literature. METHODS: A retrospective study analyzed a consecutive series of 52 patients presenting with post-traumatic discoligamentous instability of the cervical spine in which cervical interbody xenografts with plate fixations were done. Follow-up clinical evaluation for neck pain and radiologic evaluation for arthrodesis stability and xenograft fusion at various points in time were done. RESULTS: The long-term results in 41 patients were satisfactory: no infectious complications, extrusion, fracture, loss of height, or resorption of the graft. Seventy-five percent fusion was seen before 9 months after surgery, and 100% fusion was seen 3-18 months after surgery (average, 7.4 months). CONCLUSIONS: Interbody xenograft combined with a rigid plate fixation avoids the problems linked to autologous or allogenous bone graft and gives a safe and solid interbody fusion when arthrodesis is required in ligamentous instability of the cervical spine.


Assuntos
Artrodese/instrumentação , Placas Ósseas , Transplante Ósseo , Vértebras Cervicais/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Vértebras Cervicais/diagnóstico por imagem , Estudos de Avaliação como Assunto , Feminino , Seguimentos , Humanos , Ílio/transplante , Instabilidade Articular/cirurgia , Masculino , Pessoa de Meia-Idade , Radiografia , Estudos Retrospectivos , Transplante Autólogo , Transplante Heterólogo , Transplante Homólogo , Ferimentos e Lesões/cirurgia
19.
J Chir (Paris) ; 132(8-9): 353-7, 1995.
Artigo em Francês | MEDLINE | ID: mdl-8550718

RESUMO

From September 1989 to September 1994, 65 patients, 15 females and 50 males, with a mean age of 32 +/- 14 years were admitted in the emergency unit for renal trauma. In 38.5% of cases multiple trauma was present. Lesional mechanism was most frequently contusions (49.2%) and deceleration injuries (43.1%). Gross hematuria or microscopic hematuria were presents in 72.3% of cases. The sensibility of systematic abdominal echography was 100% in case of perirenal hematoma and 65% in case of parenchymatous lesions. Only 23 patients were operated (35.3%) because of low blood pressure. None secondary operation was necessary in abstention group. Global mortality was 7.7%. Postoperative morbidity was 20% and specific morbidity in abstention group was 10.7%.


Assuntos
Rim/lesões , Traumatismo Múltiplo/epidemiologia , Acidentes de Trabalho , Acidentes de Trânsito , Adolescente , Adulto , Feminino , França/epidemiologia , Hematúria/etiologia , Humanos , Rim/diagnóstico por imagem , Rim/cirurgia , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/mortalidade , Nefrectomia , Tomografia Computadorizada por Raios X , Ultrassonografia , Urografia
20.
Tex Heart Inst J ; 22(2): 202-3, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-7647609

RESUMO

We describe a patient who died due to thrombosis of the abdominal aorta and its branches after placement of an intraaortic balloon pumping device. This rare complication, which occurred despite careful insertion technique, underscores the need to select balloon size as a function of the individual patient's morphology.


Assuntos
Aorta Abdominal , Doenças da Aorta/diagnóstico , Balão Intra-Aórtico/instrumentação , Infarto do Miocárdio/cirurgia , Complicações Pós-Operatórias/diagnóstico , Trombose/diagnóstico , Idoso , Aorta Abdominal/cirurgia , Doenças da Aorta/cirurgia , Ponte de Artéria Coronária , Feminino , Humanos , Complicações Pós-Operatórias/cirurgia , Reoperação , Trombose/cirurgia
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