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Saudi Med J ; 25(7): 890-4, 2004 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15235695

RESUMO

OBJECTIVE: To evaluate our experience of management of necrotizing fasciitis (NF) particularly the role of early and aggressive surgical intervention. METHODS: This is a retrospective review of the cases affected by this disease and managed at Riyadh Medical Complex, Riyadh, Kingdom of Saudi Arabia, during 5 calendar years from 1996 through to 2000 (1416-1420 A.H). The preoperative and operative data was collected, and postoperative morbidity and mortality were analyzed. RESULTS: A total of 25 cases of NF were treated during the 5-year period, 18 were males and 7 female. The majority of patients had perianal suppuration as the primary lesion, followed by groin area in drug addicts and only 2 cases were primarily in the upper limbs. Diabetes and drug addiction were the main predisposing factors. All but 3 infections were polymicrobial, with streptococci and acinobacter being the most frequent organisms. The mainstay of treatment depends on a high index of suspicion, aggressive early and repeated debridements and adequate antibiotic coverage. The overall mortality was 24% but the drastic reduction in mortality was observed with early surgical intervention. CONCLUSION: The results highlight the role of early diagnosis; prompt and aggressive surgical debridements are critical for improved survival.


Assuntos
Infecções por Acinetobacter/cirurgia , Fasciite Necrosante/cirurgia , Infecções Estafilocócicas/cirurgia , Infecções Estreptocócicas/cirurgia , Infecções por Acinetobacter/epidemiologia , Infecções por Acinetobacter/microbiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos , Terapia Combinada , Desbridamento , Quimioterapia Combinada/uso terapêutico , Fasciite Necrosante/epidemiologia , Fasciite Necrosante/microbiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Fatores de Risco , Arábia Saudita/epidemiologia , Transplante de Pele , Infecções Estafilocócicas/epidemiologia , Infecções Estafilocócicas/microbiologia , Infecções Estreptocócicas/epidemiologia , Infecções Estreptocócicas/microbiologia , Análise de Sobrevida
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