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The dorsal approach to the scaphoid carries a risk of injuring its nutrient vessels. This cadaveric study identified a safe zone dorsally, which extends from the proximal pole to 11.3 mm distally along the scaphoid axis.Level of evidence: Level V.
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Neck pain, dizziness, difficulty supporting the head for an extended period, and impaired movement are all symptoms of cervical spine instability, which may produce cervical spondylolisthesis in patients who have more severe symptoms. To avoid problems and consequences, early detection of cervical spine instability is required. A previous study created a Thai-language version of a cervical spine instability screening tool, named the CSI-TH, and evaluated its content validity. However, other characteristics of the CSI-TH still needed to be evaluated. The objective of the current study was to assess the rater reliability and convergent validity of the CSI-TH. A total of 160 participants with nonspecific chronic neck pain were included in the study. The Neck Disability Index Thai version (NDI-TH), the Visual Analog Scale Thai version (VAS-TH), and the Modified STarT Back Screening Tool Thai version (mSBST-TH) were used to evaluate the convergent validity of the CSI-TH. To determine inter- and intra-rater reliabilities, novice and experienced physical therapists were involved. The results showed that rater reliabilities were excellent: the intra-rater reliability was 0.992 (95% CI = 0.989 ± 0.994), and the inter-rater reliability was 0.987 (95% CI = 0.983 ± 0.991). The convergent validities of the VAS-TH, NDI-TH, and mSBST-TH when compared with the CSI-TH were 0.5446, 0.5545, and 0.5136, respectively (p < 0.01). The CSI-TH was developed for use by physical therapists and is reliable. It can be used by physical therapists, whether they are experienced or novices, and has an acceptable correlation to other neck-related questionnaires. The CSI-TH is concise, suitable for clinical use, and lower-priced when compared to the gold standard in diagnosis for patients with cervical spine instability.
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Vértebras Cervicais , Instabilidade Articular , Programas de Rastreamento , Cervicalgia , Humanos , Tontura/etiologia , Idioma , Cervicalgia/diagnóstico , Cervicalgia/etiologia , Reprodutibilidade dos Testes , População do Sudeste Asiático , Instabilidade Articular/complicações , Instabilidade Articular/diagnóstico , Programas de Rastreamento/métodos , TailândiaRESUMO
SUMMARY: Anatomical variation of the foramina transversaria (FT) is associated with vertebral neurovascular symptoms and can cause complications after lower spine surgery, especially cervical pedicle screw (CPS) insertion. FT variation has been documented and classified in various populations, as this information can help increase cervical stability in subaxial vertebral surgery. Although the morphometry of the upper cervical spine in Thai populations has been reported, there have yet been no studies examining the features of FT. The FT of dried cervical spines (C3-C7; left and right side; n = 107, male = 53 and female = 54) were examined for morphological variation, and their anteroposterior (AP) and transverse (T) diameters were measured using a digital vernier caliper. Morphometric data and variations were compared by sex and lateral side. It was that the C3-C6 FT in both sexes were round, and the C7 FT was elliptical with an oblique right side. FT diameters did not differ significantly by sex except for the AP diameters of C6-C7 and for T diameters of C4 and C7. The left AP diameters of C3-C6 were significantly longer than the right, as were the T diameters of C4 and C7 FT. Additionally, T diameter was significantly longer than that of the AP, except that of the left C6 in male spines, which did not differ from the AP. Most FT examined were round. These findings should be considered in the provisional diagnosis of vertebral neurovascular symptoms caused by FT variation as well as that of neurovascular damage after cervical pedicle screw placement.
La variación anatómica del foramen transverso (FT) se asocia con síntomas neurovasculares vertebrales y puede causar complicaciones después de la cirugía de columna cervical inferior, especialmente la inserción de tornillos pediculares cervicales (TPC). La variación del FT se ha documentado y clasificado en varias poblaciones, ya que esta información puede ayudar a aumentar la estabilidad cervical en la cirugía vertebral subaxial. Aunque se ha informado sobre la morfometría de la columna cervical superior en poblaciones tailandesas, aún no se han realizado estudios que examinen las características de FT. Se examinó la variación morfológica del FT de vértebras cervicales secas (C3-C7; lado izquierdo y derecho; n = 107, hombres = 53 y mujeres = 54), y se midieron sus diámetros anteroposterior (AP) y transverso (T) usando un pie de metro digital. Se compararon datos morfométricos y variaciones por sexo y lado. Los FT de C3-a C6 en ambos sexos eran redondos, y el FT C7 era elíptico con el lado derecho oblicuo. Los diámetros del FT no difirieron significativamente por sexo excepto para los diámetros AP de C6- C7 y para los diámetros transversos de C4 y C7. Los diámetros AP izquierdos de C3-C6 eran significativamente más largos que los del lado derecho, al igual que los diámetros transversos de C4 y C7. Además, el diámetro transverso fue significativamente mayor que el AP, excepto el C6 izquierdo en las vértebras de hombres, que no difirió del AP. La mayoría de los FT examinados eran redondos. Estos hallazgos deben ser considerados en el diagnóstico provisional de síntomas neurovasculares vertebrales causados por la variación del FT, así como en el de daño neurovascular tras la colocación de tornillos pediculares cervicales.
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Humanos , Masculino , Feminino , Vértebras Cervicais/anatomia & histologia , Variação Anatômica , Tailândia , Caracteres SexuaisRESUMO
STUDY DESIGN: Randomized controlled trial. OBJECTIVES: This prospective trial aimed to compare the effectiveness of etoricoxib and acetaminophen in terms of post-operative morphine consumption and pain score in patients undergoing lumbar laminectomy. METHODS: Forty lumbar-laminectomy patients aged between 18 and 50 years were enrolled, randomized, and allocated into either the etoricoxib group or the acetaminophen group. The measures assessed were the amount of morphine consumed and pain visual analog score (VAS) at 12, 24, and 48 hours after surgery. Adverse events were recorded. RESULTS: Patients in the etoricoxib group had statistically significantly lower morphine consumption than those in the acetaminophen group at 12 hours (P-value = .006), 24 hours (P-value = .006) and 48 hours (P-value = .011). Patients in the etoricoxib group had lower VAS scores than those in the acetaminophen group at 0, 12, 24, 48 hours, the difference being statistically significant at 48 hours (P < .001). CONCLUSIONS: Compared to acetaminophen, etoricoxib can significantly reduce post-operative morphine consumption and improve the pain score at 12, 24, and 48 hours.
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OBJECTIVE: Lumbar instability is a condition that has been extensively reported in its prevalence and its effect on patients. To date, however, a clinical screening tool for this condition has not been developed for use in Thailand. The objectives of this study were to translate and test the content validity and rater reliability of a screening tool for evaluating Thai patients with lumbar instability. METHODS: The investigators selected the lumbar instability questionnaire from an original English version. Elements of the tool comprised the dominant subjective findings reported by this clinical population. The screening tool was translated into the Thai language following a process of cross-cultural adaptation. The index of item-objective congruence (IOC) was checked for content validity by 5 independent experts. Seventy-five Thai patients with chronic nonspecific low back pain were asked to report their symptoms. The interview procedure using the tool was conducted by expert and novice physical therapists, which informed the intraclass correlation coefficient (ICC) for inter- and intrarater reliability. RESULTS: The IOC was 0.95. The interrater ICC between expert and novice physical therapists was 0.92 (95% CIâ¯=â¯0.88-0.95). The intrarater ICC of novice physical therapist was 0.91 (95% CIâ¯=â¯0.86-0.94). CONCLUSION: The Thai version of the screening tool for patients with lumbar instability achieved excellent content validity and interrater and intrarater reliability. This screening tool is recommended for use with Thai patients with low back pain to identify the subpopulation with lumbar instability.
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Instabilidade Articular/diagnóstico , Vértebras Lombares/fisiopatologia , Programas de Rastreamento/normas , Doenças da Coluna Vertebral/diagnóstico , Inquéritos e Questionários/normas , Adulto , Avaliação da Deficiência , Feminino , Humanos , Idioma , Dor Lombar/diagnóstico , Masculino , Pessoa de Meia-Idade , Fisioterapeutas , Reprodutibilidade dos Testes , Tailândia , TraduçãoRESUMO
BACKGROUND: Spinal tuberculosis (TB) is a leading cause of damage to the spine and associated neural structures. PURPOSE: This study aims to identify the risk factors for neurological deterioration in spinal TB patients to promptly care for the patients before paralysis develops. METHODS: The demographics, clinical characteristics, laboratory results, and radiographic findings of spinal TB patients were collected between 1993 and 2016. The data were analyzed using logistic regression methods. The predictive factors for neurological deficit were identified. RESULTS: There were 125 spinal TB patients (70 men and 55 women). The average age ± standard deviation was 55.7 ± 2.0 and 52.3 ± 2.4=years, respectively. According to the univariate analysis, the significant risk factors associated with neurological deterioration were signal cord changes, notable Cobb angle (>30°), radiating pain, and epidural abscess. The multivariate analysis revealed that only signal cord change and notable Cobb angle significantly influenced neurological status. CONCLUSION: The predictive factors for neurological deterioration in spinal TB patients are signal cord change and notable Cobb angle. Surgery should be considered in patients who present with these factors before the development of neurological deterioration.
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Doenças do Sistema Nervoso/etiologia , Tuberculose da Coluna Vertebral/complicações , Adulto , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Doenças do Sistema Nervoso/diagnóstico por imagem , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento , Tuberculose da Coluna Vertebral/diagnósticoRESUMO
BACKGROUND: Variations of morphology of the glenoid cavity have been previously reported. These influence the surgical reconstruction or arthroplasty of the shoulder. This study aims to study the variation of the shape of suprascapular notch, shape of glenoid cavity, dimensions of both the scapular and the glenoid cavity, and predict the glenoid dimensions from the scapular dimension parameters. MATERIALS AND METHODS: Adult-dried scapulae were collected. The shapes of each suprascapular notch and glenoid cavity were evaluated. The scapular height, scapular width, glenoid superoinferior distance, and glenoid anteroposterior distance were measured using a digital vernier caliper, and statistical analysis was conducted on the data that were obtained. RESULTS: There were 264 scapulae included in this study (166 male and 98 female). Most of the glenoid cavities were pear shaped (69.7%). The two most common types of suprascapular notches were small depression notches (31.8%) and the absence of notches (25.8%). The mean ± SD of scapular height, scapular width, glenoid superoinferior distance, and glenoid anteroposterior distance were 148.2 ± 10.0, 108.1 ± 6.4, 37.1 ± 2.2, and 27.4 ± 2.1 mm, respectively, in the male samples and 133.0 ± 7.0, 97.0 ± 5.2, 33.2 ± 1.9, and 23.7 ± 1.7 mm, respectively, in the female samples. The male scapulae were significantly larger than the female scapulae (p value < 0.05). However, there were no differences between the male and female scapulae in terms of scapular index or glenoid index (p value > 0.05). Scapular height and width were significantly associated with both the glenoid superoinferior distance (p = 0.0001) and glenoid anteroposterior distance (p value = 0.0001). CONCLUSION: Scapular height and width can predict the dimensions of the glenoid. In cases of glenoid bone loss or shoulder arthroplasty, the native normal glenoid dimensions can be determined from the scapular dimensions as visualized using a true scapular anteroposterior radiograph. The surgeon can use these preoperative parameters when performing glenoid reconstruction or shoulder arthroplasty.
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Cavidade Glenoide/anatomia & histologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Cavidade Glenoide/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Tamanho do Órgão , Escápula/anatomia & histologia , Escápula/diagnóstico por imagemRESUMO
STUDY DESIGN: This study investigated the subaxial cervical pedicles from C3 to C7 to provide information for accurately transpedicular screw fixation in this region. OBJECTIVE: This study was evaluated the morphology of the subaxial cervical pedicle to determine the size and trajectory of screw fixation. SUMMARY OF BACKGROUND DATA: Cervical vertebrae are an important structure to protect the neurovascular structure. The cervical spine surgery using screw fixation is an effective method to treat the cervical spine instability. There have been many research morphological data of subaxial cervical vertebrae. However, no studies have reports on dried cervical vertebrae of Thai's people. METHODS: The measurement was conducted in 130 dried cervical vertebrae (C3-C7), including 61 males and 69 females. The measurement parameters were pedicle width (PW), pedicle length (PL), pedicle height (PH), pedicle axis length (PAL), pedicle transverse angle (PTA), and pedicle sagittal angle (PSA), which determined using ImageJ software. RESULTS: The results of morphological data of C3 to C7 was found that the mean of PW, PL, PH, PAL, PTA, and PSA that obtained from male were significantly higher than female excepted for PL (C7) and PTA (C3, C5). Except for the C6 PW, C3 PL, C4 to C5 to C7 PTA, and C4 PSA, there were no significant differences of these parameters between male and female. CONCLUSION: The appropriate pedicle screw size is 4.0âmm for C3 and C4, and 4.5âmm for C5 to C7. The results of this study are the useful information for cervical spine fixation while prevent the vascular and neurological injuries from the large screw causing pedicle breakage. LEVEL OF EVIDENCE: 3.
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Povo Asiático/estatística & dados numéricos , Vértebras Cervicais/anatomia & histologia , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/cirurgia , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Masculino , Parafusos Pediculares , Tailândia , Tomografia Computadorizada por Raios XRESUMO
STUDY DESIGN: Experimental study in an animal model. PURPOSE: This study aims to evaluate the hemostatic properties of four common hemostatic materials including the chitosan clot pad, absorbable gelatin sponge, cellulose membrane, and gauze on peridural bleeding using a rat model. OVERVIEW OF LITERATURE: Intraoperative bleeding during spinal surgery can lead to morbidities. Hemostatic materials have been developed, but the efficacy of these materials on peridural bleeding remains unclear. METHODS: Forty 8-week-old Sprague-Dawley rats were used in this study. Under adequate anesthesia, each rat was posteriorly dissected to their L5 and L6 spinous processes. Bleeding from muscles and soft tissue dissections was stopped before lumbar bone cutting. Immediately after the L5-L6 laminae were cut and removed, the rats were randomly allocated to receive one of the abovementioned hemostatic materials. All hemostatic materials were placed over the raw surface of cut bone and dura and changed every 60 seconds. The procedure was stopped when there was no further bleeding. Time to staunching and amount of bleeding were recorded for statistical analysis. RESULTS: The respective mean±standard deviation hemorrhage volume and time for the cellulose membrane, gelatin sponge, chitosan pad, and gauze were 1.19±0.44, 1.03±0.72, 0.96±0.57, and 1.98±0.62 mL, respectively, and 2.9±0.6, 2.1±0.6, 1.7±0.5, and 2.9±1.0 minutes, respectively. The overall bleeding volumes for the cellulose membrane, gelatin sponge, and chitosan pad were significantly lower than the overall bleeding volume for gauze. CONCLUSIONS: Chitosan clot pads, gelatin sponges, and cellulose membranes have better hemostatic properties than gauze. The chitosan pad had the lowest average bleeding volume, followed by gelatin sponge and cellulose membrane.
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STUDY DESIGN: Agreement study. PURPOSE: To validate the interrater reliability of the histopathological classification of the post-laminectomy epidural fibrosis in an animal model. OVERVIEW OF LITERATURE: Epidural fibrosis is a common cause of failed back surgery syndrome. Many animal experiments have been developed to investigate the prevention of epidural fibrosis. One of the common outcome measurements is the epidural fibrous adherence grading, but the classification has not yet been validated. METHODS: Five identical sets of histopathological digital files of L5-L6 laminectomized adult Sprague-Dawley rats, representing various degrees of postoperative epidural fibrous adherence were randomized and evaluated by five independent assessors masked to the study processes. Epidural fibrosis was rated as grade 0 (no fibrosis), grade 1 (thin fibrous band), grade 2 (continuous fibrous adherence for less than two-thirds of the laminectomy area), or grade 3 (large fibrotic tissue for more than two-thirds of the laminectomy area). A statistical analysis was performed. RESULTS: Four hundred slides were independently evaluated by each assessor. The percent agreement and intraclass correlation coefficient (ICC) between each pair of assessors varied from 73.5% to 81.3% and from 0.81 to 0.86, respectively. The overall ICC was 0.83 (95% confidence interval, 0.81-0.86). CONCLUSIONS: The postoperative epidural fibrosis classification showed almost perfect agreement among the assessors. This classification can be used in research involving the histopathology of postoperative epidural fibrosis; for example, for the development of preventions of postoperative epidural fibrosis or treatment in an animal model.
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PURPOSE: The purpose was to investigate the median sacral artery (MSA) anatomical pathway in terms of its relationship to the lumbosacral spine. METHODS: The posterior wall and lumbosacral spine of 54 adult embalmed cadavers were dissected. The MSA emerging point was identified. The distance from its emerging point to the lateral border of the vertebral body was measured bilaterally. The pathway of the MSA from the emerging point to the sacral promontory was described together with the MSA length. All outcomes were independently measured by two observers. Statistics on obtained data were calculated. RESULTS: Most of the MSA emerging points were at the L5 vertebral body (94.4 %). The emerging point from the right and left lateral border of the L5 vertebral body was 3.31 ± 0.54 cm and 2.39 ± 0.51 cm, respectively. The MSA then lay along the middle one-third of the anterior surface of the lumbosacral junction. The mean length between the emerging point and the sacral promontory was 2.73 ± 0.97 cm. CONCLUSIONS: The MSA anatomy is important for prevention of intra-operative bleeding. For anterior lumbosacral surgery, the MSA should be identified and controlled before proceeding with the spinal surgery. For posterior bicortical sacral screw placement, the screw tip should be fluoroscopically checked to avoid inserting the screw tip into the mid sacral promontory. By first approaching the anterior sacral promontory, the surgeon will find the MSA within the middle one-third zone, and 2.47-2.99 cm cephalad to this, the iliac vessels. Knowledge of the MSA helps the surgeon to operate more safely.
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Aorta Abdominal/anatomia & histologia , Vértebras Lombares/cirurgia , Sacro/irrigação sanguínea , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Região Lombossacral/cirurgia , Masculino , Pessoa de Meia-Idade , Pelve/cirurgia , Sacro/cirurgiaRESUMO
PURPOSE. To evaluate the outcome of percutaneous release of the A1 pulley in 40 cadaveric fingers using a modified Kirschner wire. METHODS. A 2.5-mm-diameter Kirschner wire measuring >12 cm in length was used. One end of the wire was sharpened into a 'J' shape using a grinder. The J-shaped tip featured a blunt, elongated lower tip, a sharp J-shaped curve, and a blunt upper tip. Completeness of A1 pulley release and injuries to the A2 pulley, flexor tendon, and neurovascular structures were evaluated in 40 cadaveric fingers. RESULTS. Complete release of the A1 pulley was achieved in 8 index, 7 middle, 8 ring, and 8 little fingers, whereas incomplete release of the distal part was noted in 2 index, 2 middle, 2 ring, and one little fingers; release was missed in one middle and one little fingers. Injury to the A2 pulley was noted in 2 index fingers; the injury was minimal and limited to the proximal 2 mm of the A2 pulley. There was no flexor tendon or digital nerve injury in any finger. CONCLUSION. Percutaneous release of the A1 pulley using a modified Kirschner wire achieved complete release in 78% of cadaveric fingers, which is comparable to that using a specially manufactured push knife.
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Fios Ortopédicos , Tenotomia/instrumentação , Dedo em Gatilho/cirurgia , Cadáver , Humanos , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentaçãoRESUMO
The aim of this study was to measure the version of femoral neck on dried Thai human femora. The version of femoral neck varies widely. It is important to know the version of femoral neck in a particular population to undertake successful femoral neck reconstructive surgery. Paired 216 dried femora of adult Thais from the bone collection maintained in the Department of Anatomy at the Faculty of Medicine, Khon Kaen University, Thailand, were used to measure the version of femoral neck. The mean+SD femoral anteversion (FNA) was 16.21+5.24 degrees. The 95% confidence interval of FNA was from 15.48 to 16.94 degrees. The 95% confidence intervals of male and female average FNA were 14.75 to 16.90 and 15.59 to 17.59 degrees respectively. There was no significance difference of the FNA between males and females in both anteversion and retroversion groups. The average male FNA showed no statistical difference to average female anteversion. The 95% confidence intervals of males and females average retroversion were -8.22 to -4.80 and -7.71 to -4.47 degrees respectively. The average male retroversion showed no statistical difference to average female retroversion. The overall 95% confidence interval of femoral neck anteversion and retroversion were 15.48 to 16.94 degrees and -7.33 to -5.27 with no significant difference between males and females. These degrees of FNA must be considered when the femoral neck reconstructive surgery is planned.
El objetivo fue medir el cuello femoral en fémures humanos de tailandeses adultos. La versión del cuello femoral es muy variable. Es importante conocer la versión de cuello femoral en una población en particular para llevar a cabo con éxito una cirugía reconstructiva. Se utilizaron 216 fémures secos de adultos tailandeses obtenidos de la colección del Departamento de Anatomía de la Facultad de Medicina de la Universidad de Khon Kaen, Tailandia. La anteversión femoral (AFM) media+DE fue de 16,21±5,24. El intervalo de confianza del 95% de la AFM fue entre 15,48 a 16,94. El promedio de intervalos de confianza del 95% en hombres y mujeres fue desde 14,75 a 16,90 y 15,59 a 17,59, respectivamente. No hubo diferencia significativa entre hombres y mujeres en ambos grupos de anteversión y retroversión. La AFM promedio en hombres no mostró diferencia significativa con la anteversión media de las mujeres. Se observó un promedio de -8,22 a -4,80 y -7,71 a -4,47 en el 95% de los intervalos de confianza entre hombres y mujeres, respectivamente. La retroversión promedio en hombres no mostró ninguna diferencia significativa con la retroversión media en las mujeres. Estos grados de AFM deben ser considerados en la planificación de una cirugía reconstructiva del cuello femoral.
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Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Colo do Fêmur/anatomia & histologia , Cadáver , Intervalos de Confiança , Fêmur/anatomia & histologiaRESUMO
STUDY DESIGN: Experimental study. OBJECTIVE: To evaluate the efficacy and safety of peridural parecoxib-soaked absorbable gelatin sponge, and cellulose membrane on peridural fibrosis prevention in an animal model. SUMMARY OF BACKGROUND DATA: Postoperative peridural fibrosis is one of the causes of failed back surgery syndrome. Nonsteroidal anti-inflammatory drugs inhibit the inflammatory response, while an absorbable gelatin sponge or cellulose membrane interposes between the dura and the paraspinal muscle to staunch the surgical bleeding. These mechanisms may prevent peridural fibrosis. METHODS: Forty L5-L6 laminectomized adult Sprague-Dawley rats were randomly allocated into 4 groups. The high parecoxib group received 6 mg of parecoxib soaked into an absorbable gelatin sponge placed over the dura. The low parecoxib group was given 2 mg of parecoxib soaked into an absorbable gelatin sponge. The dura in the cellulose group was covered with a cellulose membrane, while the control group received normal saline drip before surgical wound closure. All rats were killed at 6 weeks for histopathological assessment. The fibroblast density, inflammatory cell density, fibrous adherence, and adverse events were quantified. The obtained results were analyzed statistically. RESULTS: The respective mean fibroblast density in the high parecoxib, low parecoxib, cellulose, and control groups was 217.77 ± 51.76, 317.51 ± 126.92, 321.80 ± 90.94, and 328.48 ± 73.41 cells/mm², while the respective mean inflammatory cell density was 539.65 ± 236.52, 910.17 ± 242.59, 1011.84 ± 239.30, and 1261.78 ± 319.68 cells/mm². The mean fibroblast and inflammatory cell densities of the high parecoxib group were significantly lower than the control. The high parecoxib group also showed statistically less fibrous adherence than low parecoxib, cellulose, and control groups. CONCLUSION: The high-dose parecoxib-soaked absorbable gelatin sponge can prevent peridural fibrosis without complications. The low-dose parecoxib and cellulose membrane provided no significant benefit vis-à-vis prevention of peridural fibrosis, as adduced from the lack of any statistically significant difference between the test and control rats.
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Inibidores de Ciclo-Oxigenase 2/farmacologia , Dura-Máter/efeitos dos fármacos , Esponja de Gelatina Absorvível , Isoxazóis/farmacologia , Animais , Anti-Inflamatórios não Esteroides/farmacologia , Relação Dose-Resposta a Droga , Dura-Máter/patologia , Síndrome Pós-Laminectomia/etiologia , Síndrome Pós-Laminectomia/prevenção & controle , Feminino , Fibroblastos/efeitos dos fármacos , Fibroblastos/patologia , Fibrose/etiologia , Fibrose/prevenção & controle , Humanos , Laminectomia/efeitos adversos , Vértebras Lombares/cirurgia , Masculino , Modelos Animais , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/prevenção & controle , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Resultado do TratamentoRESUMO
OBJECTIVE: To evaluate the effect of surgical treatment between correction and non-correction surgery for degenerative lumbar scoliosis by systematic review method. MATERIAL AND METHOD: The database inclusions were PubMed (January 1, 1960 to March 31, 2009), EMBASE (January 1, 1985 to March 31, 2009), The Cochrane Central Register of Controlled Trials, CINAHL, Scopus, and various articles. Grey literature was searched from Scirus. The quality of the studies was graded by MINORS. Studies that were classified level I to IV were included in analysis of surgical treatment outcome in degenerative lumbar scoliosis. Patient centered outcomes, surgical outcomes, and complication were collected. Two reviewers independently assessed trial quality and extracted data. RESULTS: Seventeen studies were included in analysis comprising 598 patients with degenerative lumbar scoliosis and treated by operative treatment. Overall, 451 patients received correction procedure. All trials were non-randomized and noncomparative studies. Almost all level evidence of the study was level III to IV Overall results were comparable between correction and non-corrective operation. CONCLUSION: There were insufficient good-quality comparative studies for surgical treatment outcome comparing between corrective deformity and non-corrective procedures. The correction of deformity in degenerative lumbar scoliosis was classified Level 2C (very weak recommendations).
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Vértebras Lombares/cirurgia , Escoliose/cirurgia , Descompressão Cirúrgica , Humanos , Laminectomia , Fusão VertebralRESUMO
OBJECTIVE: Report the invention and structural analysis of the new model of anterior spinal instrumentation (KKU expandable cage) that is expandable for space filling after vertebral body resection while simultaneously stabilize the upper vertebra with the lower vertebra, to tolerate the thoracolumbar physiologic load and augment the interbody arthrodesis of the spine. MATERIAL AND METHOD: The new model of expandable anterior spinal instrumentation, named KKU expandable cage, was invented and designed using the computer. The structural property of this instrumentation was tested and analyzed using the computer based structural analysis software. RESULTS: The KKU expandable cage made out of 316L stainless steel is 0.0301044 kg in mass and 3.76305 x 10(-6) m3 for volume. The outer diameter of the device is 23 mm and the height can expand from 20 mm to 35 mm for space filling after thoracolumbar vertebrectomy. The stress in the device after applying the maximal thoracolumbar physiologic compression load (1250N) is between 11692.7 N/m2 to 94.7266 x 10(6) N/m2, less than compression strength of the 316L stainless steel (170 x 10(6) N/m2). CONCLUSION: The stainless steel 316 L KKU expandable cage for anterior spinal instrumentation can withstand the maximal thoracolumbar physiologic compression load without failure whereas its expandable property enable it to fill and fit in the space reaching the height of 35 mm. Therefore, the insertion of this device into a space after thoracolumbar or lumbar corpectomy or vertebrectomy for the vertebral osteomyelitis or vertebral metastasis is appropriate. The device can also stabilize the spine and tolerate the maximal physiologic compression load of the thoracolumbar vertebrae. Therefore, the device helps decrease the need for bone graft or bone substitute in these patients.
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Fixadores Internos , Próteses e Implantes , Coluna Vertebral/cirurgia , Fenômenos Biomecânicos , Desenho de Equipamento , Humanos , Vértebras Lombares/cirurgia , Aço Inoxidável , Vértebras Torácicas/cirurgiaRESUMO
OBJECTIVE: The purpose of the present study was to compare the sensitivity, specificity and diagnostic accuracy of a new test, named "KKU Knee Compression-Rotation Test", with the most widely used examination, McMurray test. MATERIAL AND METHOD: Sixty-eight patients aged 18 to 39 years old were included in the present study. All of these patients were interviewed for their knee injury histories and examined with both KKU knee compression-rotation and McMurray tests preoperatively. For these clinical examination tests, the sensitivity, specificity, false positive, false negative and diagnostic accuracy rates were calculated and compared with the arthroscopic findings of these patients. RESULTS: The KKU knee compression-rotation test had sensitivity, specificity, and diagnostic accuracy for detection of meniscal tear as 86.27, 88.23, and 86.76% respectively, which superior to McMurray test that was 70.59, 82.35, and 73.53%. In addition, the KKU knee compression-rotation test had false positive and false negative rates of 11.76 and 13.73% less than the 17.65 and 29.41% of McMurray test. The combination of these two tests had diagnostic sensitivity of 90.20% and positive result of both tests suggested torn meniscus with the probability of 97.14%. CONCLUSION: The KKU knee compression-rotation test for detection of torn meniscus had better rates of diagnostic sensitivity, specificity, and accuracy than McMurray test. Therefore, the KKU knee compression-rotation test can be the first line screening examination for detection of torn meniscus. However, if the patient is tested by both the KKU knee compression-rotation and the McMurray tests, it will be a better screening test because a high sensitivity and positive result of both tests suggests a diagnosis of torn meniscus accurately.