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1.
Biomed Eng Online ; 15(1): 81, 2016 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-27388324

RESUMO

BACKGROUND: We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP-BHA composite products. The cells proliferation was investigated by MTT assay and SEM. Furthermore, the antimicrobial activity of NP-BHA samples was interrogated. RESULTS: Variances in the sintering temperature (for 5 wt% NP composites) between 1000 and 1300 °C, reveal about 700 % increase in the microhardness (~100 and 775 HV, respectively). Composites prepared at 1300 °C demonstrate the greatest compression strength with comparable result for 5 wt% NP content (87 MPa), which are significantly better than those for 10 wt% and those that do not include any NP (below 60 MPa, respectively). CONCLUSION: The results suggested the optimal parameters for the preparation of NP-BHA composites with increased mechanical properties and biocompatibility. Changes in micro-hardness and compression strength can be tailored by the tuning the NP concentration and sintering temperature. NP-BHA composites have demonstrated a remarkable potential for biomedical engineering applications such as bone graft and implant.


Assuntos
Materiais Biocompatíveis/química , Engenharia Biomédica , Durapatita/química , Silicatos/química , Animais , Bovinos , Linhagem Celular Tumoral , Humanos , Teste de Materiais , Fenômenos Mecânicos , Porosidade , Temperatura
2.
J Craniofac Surg ; 19(2): 428-32, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18362721

RESUMO

Miniplates have been used for mandibular angle fractures during the past 2 decades. The technique of placing single miniplate at the upper border based on the tension lines of the fracture was proposed by Michelet and Champy. The need for a second miniplate to be applied to the lower mandible has been discussed recently. Biomechanical comparison of biplanar and monoplanar dual-miniplate fixation techniques was investigated by Haug. Our hypothesis is in dual-miniplate fixation; the proximal 3 holes of superior border miniplate could be fixated by bicortical screws. The first 2 are at the proximal bone segment and are not related to the tooth and also superior to the alveolar nerve. Generally, the third molar tooth is extracted because it is at the fracture site. Hence, the proximal third hole could also be fixated by bicortical screws. We define a biplanar dual-miniplate technique in which the lower plate and the proximal 3 holes of the upper plate are fixated by bicortical screws. We have designed a study for biomechanical comparison of our method and popular types of mandibular fixation methods.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas/métodos , Fraturas Mandibulares/cirurgia , Animais , Materiais Biocompatíveis , Fenômenos Biomecânicos , Placas Ósseas/classificação , Parafusos Ósseos , Fixação Interna de Fraturas/instrumentação , Mandíbula/cirurgia , Maleabilidade , Ovinos , Estresse Mecânico , Propriedades de Superfície , Titânio
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