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Nat Prod Res ; 34(7): 995-1001, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30584781

RESUMO

Ethanol extracts of different parts of Passiflora cincinnata were obtained by maceration. The total phenolic and flavonoid contents were evaluated. The antioxidant activities were determined by ß-carotene-linoleic acid bleaching test, 2,2-diphenyl-1-picrylhydrazil (DPPH), and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging. The crude ethanol stem extract showed the highest amount of total polyphenols (45.53 mg gallic acid equivalent/g) while the highest total flavonoid contents (1.42 mg of quercetin equivalent/g) were observed in the leaf extract. The lowest IC50 (25.65 µg/ml) by the DPPH method was observed for the stem extract. The ABTS method showed a significant antioxidant activity for all investigated extracts. The secondary metabolite composition of ethanol extracts was assessed by HPLC-DAD-MS/MS analysis, leading to the identification of fourteen secondary metabolites in P. cincinnata extracts. These results showed the potentiality of this species as a source of phenolic compounds and antioxidants.


Assuntos
Antioxidantes/química , Flavonoides/análise , Passiflora/química , Fenóis/análise , Extratos Vegetais/química , Metabolismo Secundário , Antioxidantes/farmacologia , Cromatografia Líquida de Alta Pressão/métodos , Flavonoides/química , Polifenóis/análise , Quercetina/análise , Espectrometria de Massas em Tandem/métodos
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