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1.
J Bone Joint Surg Am ; 96(21): 1785-92, 2014 Nov 05.
Artigo em Inglês | MEDLINE | ID: mdl-25378505

RESUMO

BACKGROUND: Acetabular retroversion is associated with pincer-type femoroacetabular impingement and can lead to hip osteoarthritis. We report the ten-year results of a previously described patient cohort that had corrective periacetabular osteotomy for the treatment of symptomatic acetabular retroversion. METHODS: Clinical and radiographic parameters were assessed preoperatively and at two and ten years postoperatively. A Kaplan-Meier survivorship analysis of the twenty-two patients (twenty-nine hips) with a mean follow-up (and standard deviation) of 11 ± 1 years (range, nine to twelve years) was performed. In addition, a univariate Cox regression analysis was done with conversion to total hip arthroplasty as the primary end point and progression of the osteoarthritis, a fair or poor result according to the Merle d'Aubigné score, or the need for revision surgery as the secondary end points. RESULTS: The mean Merle d'Aubigné score improved significantly from 14 ± 1.4 points (range, 12 to 17 points) preoperatively to 16.9 ± 0.9 points (range, 15 to 18 points) at ten years (p < 0.001). There were also significant improvements with regard to hip flexion (p = 0.003), internal rotation (p = 0.003), and adduction (p = 0.002) compared with the preoperative status. No significant increase of the mean Tönnis osteoarthritis score was seen at ten years (p = 0.06). The cumulative ten-year survivorship, with conversion to a total hip arthroplasty as the primary end point, was 100%. The cumulative ten-year survivorship in achievement of one of the secondary end points was 71% (95% confidence interval, 54% to 88%). Predictors for poor outcome were the lack of femoral offset creation and overcorrection of the acetabular version resulting in excessive anteversion. CONCLUSIONS: Anteverting periacetabular osteotomy for acetabular retroversion leads to favorable long-term results with preservation of the native hip at a mean of ten years. Overcorrection resulting in excessive anteversion of the hip and omitting concomitant offset creation of the femoral head-neck junction are associated with an unfavorable outcome.


Assuntos
Acetábulo/patologia , Osteotomia/métodos , Acetábulo/cirurgia , Adolescente , Artroplastia de Quadril , Feminino , Seguimentos , Articulação do Quadril/fisiopatologia , Humanos , Estimativa de Kaplan-Meier , Pelve/diagnóstico por imagem , Radiografia , Análise de Regressão , Resultado do Tratamento
2.
Invest Radiol ; 44(12): 793-9, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19884825

RESUMO

OBJECTIVE: The detection rate of pulmonary emboli (PE) with computed tomography angiography (CTA) using either a standard or a low-dose protocol, combining reduced radiation exposure and iodine delivery rate, was retrospectively analyzed in a matched cohort of 120 patients. MATERIALS AND METHODS: The study was performed according to the regulations of the institutional review board. Four groups of 30 patients each, with a body weight of less than 100 kg and receiving pulmonary CTA were matched by age (range, 21-87 years), gender (female/male, 48/72), weight (range, 41-99 kg), and cross sectional area of the chest (range, 468-885 cm2). Sixty patients had PE and 60 patients had no PE at CTA. The CT tube voltage was either 80 kVp (group A, with PE and group B, with no PE) or 120 kVp (group C, with PE and group D, with no PE). Volume and flow rate of injected contrast medium was lower with the 80 kVp protocol (75 mL at 3 mL/s) compared with the 120 kVp protocol (100 mL at 4 mL/s). Contrast-to-noise ratio (CNR) for the pulmonary trunk was calculated. Two independent readers analyzed all CTAs in a randomized order for the localization of emboli, diagnostic confidence, and image quality. The reference standard for the presence of emboli involved consensus reading and assessment of available clinical data and findings with additional imaging modalities. CNR, subjective image quality, diagnostic confidence, sensitivity, and specificity for emboli at both tube voltages were compared. RESULTS: All patients with PE were correctly identified with both protocols, corresponding to a sensitivity of 100% at the patient level. For the localizations with emboli, both the sensitivity (83.7% at 80 kVp and 83.6% at 120 kVp; P = 0.921) and the specificity (97.2% at 80 kVp and 97.8% at 120 kVp; P = 0.463) were not significantly different at the 2 tube voltages. The diagnostic confidence was not different at all ramification levels (P = 0.216-1.0). CNR did not differ between the groups (P = 0.202). The overall subjective image quality was higher at 120 kVp compared with 80 kVp (P = 0.017). CONCLUSION: Detection rate and diagnostic confidence for the presence of pulmonary emboli with low-dose pulmonary CTA using 80 kVp and reduced iodine delivery rate may be equal to that at 120 kVp in patients weighing less than 100 kg.


Assuntos
Angiografia/métodos , Carga Corporal (Radioterapia) , Meios de Contraste/administração & dosagem , Embolia Pulmonar/diagnóstico por imagem , Proteção Radiológica/métodos , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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