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1.
SAGE Open Med Case Rep ; 11: 2050313X231205800, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37860284

RESUMO

Intramuscular hemangiomas are uncommon benign endotheliomas that typically occur in the trunk and limbs. Head and neck involvement is relatively infrequent, with the masseter muscle being the most commonly affected site. We present a rare case of intramuscular hemangiomas arising from the semispinalis muscle. A 31-year-old male presented with a painless swelling in the left upper neck region, gradually increasing in size over the past year. Imaging studies revealed a well-defined mass originating from the semispinalis muscle. Surgical excision was performed successfully, and histological examination confirmed the diagnosis of a mixed intramuscular hemangioma. The patient remained recurrence-free during the 2-year follow-up period. Intramuscular hemangiomas in the posterior neck muscles are rare, with only a few reported cases. Wide surgical resection with control of feeding vessels is the optimal treatment, and follow-up is recommended to monitor for local recurrence. This case report highlights the clinical presentation, diagnostic challenges, and successful surgical management of intramuscular hemangiomas in a unique location, emphasizing the importance of accurate diagnosis and appropriate treatment of this rare tumor.

3.
F1000Res ; 12: 206, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38314321

RESUMO

Background: Postoperative pain increases the risk of postoperative complications and may predispose patients to chronic post-surgical pain. This study aims to evaluate the impact of ketamine wound infiltration versus placebo at the end of thyroid surgery on postoperative pain and analgesic requirements. Methods: In this randomized controlled trial, we prospectively studied patients who underwent thyroid surgery. Patients were randomized into two groups: group S, where local infiltration was performed using 10 ml of a physiological saline solution; and group K, where 10 ml of a solution containing 2 mg/kg ketamine was infiltrated. Standardized thyroidectomies were performed in the 2 groups. Pain perception was measured using a visual analog scale (VAS) every 10 minutes in the post-anesthetic care unit (PACU) for 2 hours and thereafter every 6 hours during the first 24 hours. The opioid requirement in the PACU was evaluated. A comparison between the 2 groups was carried out. Results: Postoperatively, the mean VAS was higher in group S compared to group K during all PACU stay periods and the first 24 hours. Pain scores during swallowing were significantly lower for group K in the PACU at 0, 10, and 20 minutes. The mean morphine consumption in the PACU was 0.71 mg and 0 mg respectively in group S and group K (p=0.03). The incidence of nausea and vomiting was similar in both groups. Conclusions: Ketamine wound infiltration is an efficient modality to reduce postoperative opioid consumption compared to a placebo after thyroid surgery.


Assuntos
Analgesia , Ketamina , Humanos , Ketamina/uso terapêutico , Ketamina/efeitos adversos , Analgésicos Opioides , Glândula Tireoide/cirurgia , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/etiologia
4.
Ear Nose Throat J ; : 1455613221145277, 2022 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-36472409

RESUMO

While gastric cancer often metastasizes to the liver, lymph nodes, and lungs, skeletal muscle metastasis is a rare event. The most common primary tumor metastasizing to the extraocular structures is breast cancer. Gastric carcinoma metastatic to the extraocular muscles is a rare event announcing a spreading disease with a bad prognosis. Here, we report a case of an asymptomatic gastric carcinoma metastasizing to the superior oblique muscle diagnosed via an endoscopic endonasal biopsy.

5.
Iran J Otorhinolaryngol ; 34(125): 275-280, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36474493

RESUMO

Introduction: Few studies evaluated the treatment of postoperative pain in middle ear surgery. Materials and Methods: We conducted a randomized clinical trial to evaluate the efficacy of dexamethasone in the management of postoperative pain in middle ear surgery. Group G1 received an intravenous injection of 2 ml of physiological saline 30 minutes before the end of the procedure. Group G2 received a 2 ml intravenous solution containing 8 mg of dexamethasone, 30 minutes before the end of the procedure. Pain perception was measured by the Visual analog scale (VAS) every 10 min during the first hour and then every 6 hours during the 24 hours postoperatively. The delay of the first analgesic demand and the consumption of analgesics use during the first 24 hours postoperatively, were recorded. Results: VAS values were lower in G2at all measurement points during the first hour, as well as the first 24h postoperatively (Mann-Whitney test, P<0.05).The delay of the analgesic request was (0 (0-60) for G1 versus 0 (0-80) for G2, P=0.04, Mann-Whitney test). Morphine was used in 44% of the patients in G1 against 19% for G2 (P = 0.031). There was a significant difference between G1 and G2 in terms of the total dose of morphine consumed (P= 0.028, Mann-Whitney test). Paracetamol demand was lower in group 2 at all points of assessment during the first 24 hours postoperatively. Conclusions: Intravenous dexamethasone is effective in decreasing pain and analgesic requirement, during the first 24 hours postoperatively, in patients undergoing middle ear surgery.

6.
Ear Nose Throat J ; : 1455613221119047, 2022 Aug 09.
Artigo em Inglês | MEDLINE | ID: mdl-35943955

RESUMO

Metastasis to the nasopharynx is a rare clinical entity. Breast carcinoma is one of the primary tumors that can be responsible for a nasopharyngeal metastasis, which is an extremely rare occurrence. We report the case of a 50-year-old woman with a history of a confirmed breast carcinoma under chemotherapy who presented to our department with a unilateral hearing loss and tinnitus. Nasal endoscopy revealed a small bulging mass at the posterior wall of the nasopharynx. The biopsy of the lesion showed an infiltration of the nasopharyngeal mucosa by a mammary adenocarcinoma that was positive for estrogen and progesterone receptors and negative for human epidermal growth factor receptor 2. Computed tomography scan revealed a thickening of the nasopharyngeal mucosa, a pleural and pericardial effusion and diffused secondary bone lesions. The patient received chemotherapy. Control revealed a partial regression of the nasopharyngeal mass. The patient is still under chemotherapy.

7.
F1000Res ; 11: 1355, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36636474

RESUMO

Background: Hemithyroidectomy is one of the most common procedures performed. It is used to treat patients with benign unilateral nodules. Hemithyroidectomy results in fewer risks of hypothyroidism and the need for thyroid hormone replacement therapy. The present study was designed to identify potential clinicopathologic risk factors associated with the onset of biochemical hypothyroidism. Methods: We conducted a retrospective review of all patients who underwent hemithyroidectomy between 2004 and 2019. Hypothyroidism was defined as a serum thyrotropin level greater than 5 mIU/L. The patients were analyzed for age, sex, preoperative and postoperative thyroid stimulating hormone (TSH), state, side, and volume of the remaining lobe, and histologic diagnosis. Results: Hypothyroidism was diagnosed in 30.8% of 214 patients. This complication appeared in the first year in 83.3% of the cases. A preoperative TSH level greater than 1.32 mIU/l, a remaining volume of the lobe less than 3 ml, and the presence of thyroiditis were associated with a significant increase in the risk of developing hypothyroidism (p<0.01). There were no significant differences in age, sex, state, and side of the remaining lobe. The mean thyroxine dose was 57 ± 26 micrograms. Conclusions: The risk of hypothyroidism after hemithyroidectomy should be assessed prior to surgery. Close monitoring is recommended in patients at high risk of developing this complication. However, all patients who undergo hemithyroidectomy should be monitored at least for the first year.


Assuntos
Hipotireoidismo , Humanos , Hipotireoidismo/etiologia , Tireoidectomia/efeitos adversos , Tireoidectomia/métodos , Tireotropina , Tiroxina , Fatores de Risco
8.
SAGE Open Med Case Rep ; 9: 2050313X211066648, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34987819

RESUMO

Parathyroid cysts are an uncommon entity. They are classified as functioning and nonfunctioning cysts. Cyst aspiration with detection of parathyroid hormone is a useful tool to confirm the diagnosis. Here, we report four cases of parathyroid cysts. One patient had a functioning cyst. Ultrasonography of the neck revealed a cystic lesion behind the left lobe of the thyroid gland in two cases and a right cystic thyroid nodule in two cases. The cysts exerted a mass effect on the adjacent structures in two cases without clinical compressive symptoms. Fine-needle aspiration with detection of parathyroid hormone in the cyst fluid was performed in one case (nonfunctioning cyst): intracystic parathyroid hormone level was high. Recurrence was noted 1 month after the cyst aspiration. All patients underwent surgical treatment. Our series is characterized by two cases of nonfunctioning intrathyroidal parathyroid cysts which are very uncommon. They are mistaken for thyroid cysts. After surgery, no recurrence was noted. We aim to describe the epidemiological, clinical, and paraclinical features of this condition as well as its therapeutic modalities.

9.
Braz. j. otorhinolaryngol. (Impr.) ; 85(5): 617-622, Sept.-Oct. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1039286

RESUMO

Abstract Introduction: The fine-needle cytology is being used as a first line of investigation in the diagnosis of head and neck swellings, as it is simple, cost effective and less invasive as compared to biopsy. Objective: The aims of this study were to evaluate the results of the fine-needle non-aspiration cytology of cervical lymphadenopathy and to study the factors influencing the rate of non-diagnosis results. Methods: This retrospective study was conducted on selected patients with cervical lymphadenopathy that had undergone a fine-needle non-aspiration cytology followed by a histological biopsy. The sensitivity, specificity, positive predictive value and negative predictive value of fine-needle non-aspiration cytology for diagnosing tuberculosis were estimated. The risk factors of non-diagnosis results were evaluated. Results: The sensitivity, specificity, positive predictive value rates of fine-needle non-aspiration cytology for tuberculosis were 83.3%, 83.3%, 78.9% and 86.9% respectively. In total, 47 out of the 131 samples (35.8%) were considered non-diagnosis. Of the non-diagnosis samples, 84.2% (38 out of 47) were benign mostly due to tuberculosis (30 cases). Among the studied factors, only tuberculosis (confirmed by histopathological examination) was significantly associated with non-diagnosis cytology (p = 0.02, Odds-Ratio = 2.35). Conclusion: Tuberculosis is currently the commonest cause of cervical lymphadenopathy in North Africa. Fine-needle non-aspiration cytology is safe and accurate in the diagnosis of cervical tuberculous lymph node that is associated with the risk of non-diagnosis cytology.


Resumo Introdução: A punção não aspirativa com agulha fina tem sido utilizada como primeira linha de investigação no diagnóstico de tumores de cabeça e pescoço, por ser uma técnica simples, custo-efetiva e menos invasiva quando comparada à biópsia. Objetivo: Os objetivos deste estudo foram avaliar os resultados de citologia por punção não-aspirativa com agulha fina de linfadenopatias cervicais e estudar os fatores que influenciam a taxa de falha diagnóstica. Método: Este estudo retrospectivo foi realizado em pacientes selecionados com linfadenopatia cervical submetidos a punção não aspirativa com agulha fina, seguida por biópsia histológica. Foram estimadas a sensibilidade, especificidade, o valor preditivo positivo e valor preditivo negativo da punção não aspirativa com agulha fina para o diagnóstico de tuberculose. Os fatores de risco dos resultados com falha diagnóstica foram avaliados. Resultados: As taxas de sensibilidade, especificidade, valor preditivo positivo e valor preditivo negativo da punção não aspirativa com agulha fina para tuberculose foram de 83,3%, 83,3%, 78,9% e 86,9%, respectivamente. Das 131 amostras, 47 (35,8%) foram consideradas como falha diagnóstica. Das amostras não diagnosticadas, 84,2% (38 de 47) eram benignas, principalmente devido à tuberculose (30 casos). Entre os fatores estudados, apenas a tuberculose (confirmada pelo exame histopatológico) estava significativamente associada à citologia com falha diagnóstica (p = 0,02, odds ratio = 2,35). Conclusão: A tuberculose é atualmente a causa mais comum de linfadenopatia cervical no norte da África. A punção não aspirativa com agulha fina é uma técnica segura e precisa no diagnóstico de linfonodos cervicais associados ao risco de citologia com falha diagnóstica.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Tuberculose dos Linfonodos/diagnóstico , Biópsia por Agulha Fina/métodos , Linfonodos/patologia , Tuberculose dos Linfonodos/patologia , Estudos Retrospectivos
10.
Pan Afr Med J ; 32: 24, 2019.
Artigo em Francês | MEDLINE | ID: mdl-31143329

RESUMO

Osteoblastoma is a rare benign bone tumor, accounting for 1% of all bone tumors. It mainly occurs in the long bones, more rarely in the jaws. Osteoblastoma of the jaws mainly involves the mandible while nasosinusal involvement is very rare. The diameter of the tumor can grow to 10 cm. On X-ray, the tumor may appear as a well or poorly defined clear lesion, usually scattered with mineral patches. Recurrence rate is very low after surgical resection as well as the risk of malignant transformation. We report the case of a 13-year old female patient presenting with nasal obstruction evolving over the last 3 months associated with episodes of epistaxis and left blurred vision. Clinical examination showed voluminous nasal concha with polyploid mucosa filling all the left nasal fossa with left axial exophthalmos. CT scan of the facial massif showed left frontoethmoidal expansive process measuring 50*47*36 mm, spontaneously hypodense, heterogeneous, non enhanced after injection of the Contrast materials, responsible for destruction of the ethmoidal labyrinth, swelling of the bony walls with mass effect on the ipsilateral orbit. The suspected diagnosis was frontoethmoidal mucocele. Hence, the decision to perform endonasal surgery. Whitish thick liquid was collected by the cranial portion of the middle nasal concha sugesting infected mucocele. Resection of the middle nasal concha was performed. The histological examination showed osteoblastoma of the middle nasal concha . Outcome was marked by regression of the exophthalmos with no recurrence during 1-year follow up period.


Assuntos
Neoplasias Ósseas/diagnóstico , Obstrução Nasal/etiologia , Neoplasias Nasais/diagnóstico , Osteoblastoma/diagnóstico , Adolescente , Neoplasias Ósseas/patologia , Neoplasias Ósseas/cirurgia , Exoftalmia/etiologia , Feminino , Seguimentos , Humanos , Mucocele/diagnóstico , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia , Osteoblastoma/patologia , Osteoblastoma/cirurgia , Tomografia Computadorizada por Raios X/métodos
11.
Braz J Otorhinolaryngol ; 85(5): 617-622, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30017875

RESUMO

INTRODUCTION: The fine-needle cytology is being used as a first line of investigation in the diagnosis of head and neck swellings, as it is simple, cost effective and less invasive as compared to biopsy. OBJECTIVE: The aims of this study were to evaluate the results of the fine-needle non-aspiration cytology of cervical lymphadenopathy and to study the factors influencing the rate of non-diagnosis results. METHODS: This retrospective study was conducted on selected patients with cervical lymphadenopathy that had undergone a fine-needle non-aspiration cytology followed by a histological biopsy. The sensitivity, specificity, positive predictive value and negative predictive value of fine-needle non-aspiration cytology for diagnosing tuberculosis were estimated. The risk factors of non-diagnosis results were evaluated. RESULTS: The sensitivity, specificity, positive predictive value rates of fine-needle non-aspiration cytology for tuberculosis were 83.3%, 83.3%, 78.9% and 86.9% respectively. In total, 47 out of the 131 samples (35.8%) were considered non-diagnosis. Of the non-diagnosis samples, 84.2% (38 out of 47) were benign mostly due to tuberculosis (30 cases). Among the studied factors, only tuberculosis (confirmed by histopathological examination) was significantly associated with non-diagnosis cytology (p=0.02, Odds-Ratio=2.35). CONCLUSION: Tuberculosis is currently the commonest cause of cervical lymphadenopathy in North Africa. Fine-needle non-aspiration cytology is safe and accurate in the diagnosis of cervical tuberculous lymph node that is associated with the risk of non-diagnosis cytology.


Assuntos
Biópsia por Agulha Fina/métodos , Linfonodos/patologia , Tuberculose dos Linfonodos/diagnóstico , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tuberculose dos Linfonodos/patologia , Adulto Jovem
12.
Eur Arch Otorhinolaryngol ; 275(5): 1265-1270, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29536252

RESUMO

BACKGROUND AND OBJECTIVE: We conducted a prospective double-blind randomized study assessing bupivacaine end-of-surgery wound infiltration for pain relief in thyroid surgery. METHODS: Patients were randomly divided into two groups: Group S, local wound infiltration with saline solution; Group B, bupivacaine 0.5% was administered. Pain perception was measured using visual analogue scale (VAS) during post-anaesthetic care unit (PACU) stay every 10 min and during the 24 postoperative hours admission at 2, 4, 6, 12, and 24 h after surgery. The total consumption of analgesics (morphine and nefopam) was recorded. RESULTS: Sixty patients were studied. The VAS scores were significantly lower in the bupivacaine administered group in the post-anaesthetic care unit (PACU) at 0, 10, 20, 30, 40, 50 and 60 min, and during the hospital stay at hours 6, 12, 18 and 24. The number of patients who required postoperative opioid rescue was significantly lower in group B. No patient in group B developed neurological or cardiological complications after infiltration. CONCLUSION: Bupivacaine application is effective in decreasing postoperative pain and analgesic requirement during the hospital stay for patients with thyroidectomy.


Assuntos
Bupivacaína/administração & dosagem , Dor Pós-Operatória/prevenção & controle , Tireoidectomia , Adulto , Idoso , Anestésicos Locais/administração & dosagem , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor/métodos , Estudos Prospectivos , Glândula Tireoide/cirurgia , Tireoidectomia/efeitos adversos , Tireoidectomia/métodos , Resultado do Tratamento
18.
Pan Afr Med J ; 26: 102, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28491233
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