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Br J Cancer ; 107(6): 925-30, 2012 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-22878372

RESUMO

BACKGROUND: Paracentesis for malignant ascites is usually performed as an in-patient procedure, with a median length of stay (LoS) of 3-5 days, with intermittent clamping of the drain due to a perceived risk of hypotension. In this study, we assessed the safety of free drainage and the feasibility and cost-effectiveness of daycase paracentesis. METHOD: Ovarian cancer admissions at Hammersmith Hospital between July and October 2009 were audited (Stage 1). A total of 21 patients (Stage 2) subsequently underwent paracentesis with free drainage of ascites without intermittent clamping (October 2010-January 2011). Finally, 13 patients (19 paracenteses, Stage 3), were drained as a daycase (May-December 2011). RESULTS: Of 67 patients (Stage 1), 22% of admissions and 18% of bed-days were for paracentesis, with a median LoS of 4 days. In all, 81% of patients (Stage 2) drained completely without hypotension. Of four patients with hypotension, none was tachycardic or symptomatic. Daycase paracentesis achieved complete ascites drainage without complications, or the need for in-patient admission in 94.7% of cases (Stage 3), and cost £954 compared with £1473 for in-patient drainage. CONCLUSIONS: Free drainage of malignant ascites is safe. Daycase paracentesis is feasible, cost-effective and reduces hospital admissions, and potentially represents the standard of care for patients with malignant ascites.


Assuntos
Procedimentos Cirúrgicos Ambulatórios , Ascite/cirurgia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/economia , Paracentese/efeitos adversos , Paracentese/economia , Adulto , Idoso , Procedimentos Cirúrgicos Ambulatórios/efeitos adversos , Procedimentos Cirúrgicos Ambulatórios/economia , Ascite/diagnóstico por imagem , Ascite/economia , Ascite/etiologia , Análise Custo-Benefício , Gerenciamento Clínico , Estudos de Viabilidade , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Londres , Prontuários Médicos , Pessoa de Meia-Idade , Cuidados Paliativos/métodos , Paracentese/métodos , Segurança do Paciente , Radiografia , Estudos Retrospectivos , Resultado do Tratamento , Reino Unido
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