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1.
J Pharm Bioallied Sci ; 13(Suppl 1): S19-S22, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34447036

RESUMO

The availability of different wavelengths of lasers has created a surgical panacea in the last decade and laser technology has become the standard of care for many oral and maxillofacial surgical procedures. In this article, based on literature search, we have reviewed the usage of laser in maxillofacial surgery based on the current evidence available on laser-assisted maxillofacial surgery, in PubMed database.

2.
J Med Life ; 13(3): 418-425, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33072218

RESUMO

The study aimed to investigate whether a 3D printed beta-tricalcium phosphate (ß-TCP) scaffold tethered with growth factors and fibrin glue implanted autologous bone marrow-derived mesenchymal stem cells would provide a 3D platform for bone regeneration resulting in new bone formation with plasticity. Twenty 3D printed ß-TCP scaffolds, ten scaffolds engrained with osteogenic mesenchymal stem cells with fibrin glue (group A), and ten scaffolds used as a control group with ß-TCP scaffold and fibrin glue inoculation only (group B) were included in the study. Cell infiltration, migration, and proliferation of human osteogenic stem cells on the scaffolds were executed under both static and dynamic culture conditions. Each scaffold was examined post culture after repeated changes in the nutrient medium at 2, 4 or 8 weeks and assessed for opacity and formation of any bone-like tissues macroscopic, radiographic, and microscopic evaluation. Significant changes in all the prerequisite parameters compiled with an evaluated difference of significance showing maxillofacial skeletal repair via tissue engineering by ß-TCP scaffold and MSCs remains will be the most promising alternative to autologous bone grafts and numerous modalities involving a variety of stem cells, growth factors from platelet-rich fibrin.


Assuntos
Fosfatos de Cálcio/farmacologia , Adesivo Tecidual de Fibrina/farmacologia , Peptídeos e Proteínas de Sinalização Intercelular/farmacologia , Anormalidades Maxilofaciais/terapia , Transplante de Células-Tronco Mesenquimais , Células-Tronco Mesenquimais/citologia , Impressão Tridimensional , Engenharia Tecidual/métodos , Estudos de Casos e Controles , Sobrevivência Celular/efeitos dos fármacos , Humanos , Anormalidades Maxilofaciais/diagnóstico por imagem , Anormalidades Maxilofaciais/patologia , Células-Tronco Mesenquimais/efeitos dos fármacos , Minerais/análise , Alicerces Teciduais/química , Resultado do Tratamento
3.
J Maxillofac Oral Surg ; 16(4): 453-464, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29038628

RESUMO

The aim of this study is to investigate the position and course of the mandibular canal through the ramus, angle and body of mandible using computed tomographic (CT) imaging pre-operatively and to relate these predetermined values intra-operatively to perform sagittal split ramus osteotomies. Pre-operative CT scans were taken and four points were marked at mandibular foramen, mandibular angle, mandibular body and midpoint and different dimensions of IAN were measured to localize the inferior alveolar nerve. With the obtained values, precise osteotomy cuts were made intra-operatively and intra-operative measurements for position of IAN were noted. Based on the preoperative CT measurements, the chance to encounter IAN bundle, during surgery was evaluated. The present study proved that pre-operative CT imaging prior to BSSO surgical procedure is an effective way to investigate the position and course of the IAN canal through the framework of the mandible and by interpolating these dimensions intra operatively, reduces the risk of direct injury to the IAN bundle.

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