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1.
Acta Med Okayama ; 78(1): 9-13, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38419309

RESUMO

Bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer frequently causes an intraprostatic BCG granuloma. We investigated the optimal timing for a prostate biopsy after BCG treatment by retrospectively analyzing the cases of 22 patients with non-muscle-invasive bladder cancer who underwent a prostate biopsy after BCG treatment at our institute (2013-2017). Biopsies were indicated for a rising prostate-specific antigen (PSA) level, positive digital rectal examination findings, or the appearance of de novo low apparent diffusion coefficient lesions on MRI. The control group was comprised of 28 age- and PSA-matched patients. The relationships among the cancer detection rate and the patients' PSA levels and MRI findings were analyzed. Prostate cancer was detected by biopsy in only 13.9% (3/22) of the patients in the BCG group but in 78.5% (22/28) of the control patients (p=0.0001). The three patients in the BCG group in whom prostate cancer was detected had all undergone the biopsy > 1 year after their BCG treatment. The remaining biopsies were performed within 1 year after BCG treatment and resulted in no diagnoses of prostate cancer. We suggest that performing a prostate biopsy early after BCG treatment is not informative or useful.


Assuntos
Neoplasias não Músculo Invasivas da Bexiga , Neoplasias da Próstata , Neoplasias da Bexiga Urinária , Masculino , Humanos , Vacina BCG/uso terapêutico , Próstata/patologia , Antígeno Prostático Específico , Estudos Retrospectivos , Neoplasias da Bexiga Urinária/tratamento farmacológico , Biópsia , Neoplasias da Próstata/tratamento farmacológico , Neoplasias da Próstata/patologia , Recidiva Local de Neoplasia/patologia , Invasividade Neoplásica/patologia
2.
Urol Case Rep ; 40: 101890, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34777997

RESUMO

A 21-year-old male presented to our hospital for life-threatening pelvic fracture, mandating emergent transarterial embolization of the right internal pudendal artery. At five-month post-injury, penile arterial flow was severely impaired, thus penile revascularization surgery were planned, before attempting urethroplasty for a 2-cm gap in the posterior urethra. However, reevaluation angiography results obtained two months later revealed spontaneous recovery of penile arterial flow. Excision and primary anastomosis urethroplasty was successfully performed without signs of bulbar ischemia. This case suggests that the timing of urethroplasty following pelvic injury should be tailored according to recovery of penile arterial flow.

3.
Nihon Hinyokika Gakkai Zasshi ; 112(3): 146-149, 2021.
Artigo em Japonês | MEDLINE | ID: mdl-35858810

RESUMO

A 36-year-old male with right scrotal induration visited a local physician and ultrasonography showed a mass in the right testicle. He was referred to our hospital, where an additional ultrasonography examination revealed a 1×1-cm mass with clear borders, a heterogeneous interior, slight hyperintensity, and abundant blood flow in the upper part of the right testis. Contrast-enhanced computed tomography results indicated a massive lesion with an uneven contrast effect in the right testis and no evidence of metastasis, while magnetic resonance imaging showed the tumor with bleeding and internal heterogeneity. All tumor markers were negative. Under a diagnosis of primary germ cell tumor of the testis without metastasis, a high orchiectomy was performed. The pathological diagnosis was sertoli cell tumor. Histopathologically, the tumor was benign and no additional treatment was performed. Three years after the operation, the patient was well and without complications.

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