Conjunctival Biopsy of a Patient With Mpox.

This case report describes a conjunctival biopsy of a patient with mpox infection.

Pterygium Surgery Utilizing Limbal Conjunctival Autograft and Subconjunctival Amniotic Membrane Graft in High-Risk Populations.

OBJECTIVE: To measure the outcomes of primary pterygium excision with a limbal conjunctival autograft when combined with the adjunctive use of a prophylactic subconjunctival graft of amniotic membrane to decrease the recurrence rate after surgery in an ethnically diverse population with a statistically higher risk for recurrence (African American, Asian, Caribbean, Asian, Latin). DESIGN: This is a retrospective, non-comparative study of post-operative outcomes. PARTICIPANTS: A total of 355 patients, totaling 493 eyes, with clinically significant, primary pterygia. PATIENTS AND METHODS: Patients were enrolled into the study based on the need for pterygium surgery and if they underwent primary pterygium excision with conjunctival autograft with subconjunctival amniotic membrane placement. Patients with recurrent pterygium or those with pseudopterygium were excluded from this study. All surgeries took place at the Florida Eye Microsurgical Institute (Boynton Beach, FL) between June 2006 and October 2013 by a single surgeon (BAS). Patients were seen on post-operative day 1, 7, 30, 90, 180 and 365 to evaluate for pterygium recurrence. Pterygium recurrence is defined in this study as growth greater than 1 mm past the corneal limbus at or after 6 months. RESULTS: There were six cases of recurrent pterygium for a recurrence rate of 1.22% ± 0.97% (n=493, p=0.05). Follow-up ranged from 6 months to 6 years (mean 28 months). CONCLUSION: Primary pterygium excision with a limbal conjunctival autograft and placement of a subconjunctival amniotic membrane graft has a low recurrence rate consistent with previously published data.

Pterygium excision with conjunctival autograft and subconjunctival amniotic membrane as antirecurrence agents.

OBJECTIVE: To determine the outcome of pterygium excision with a conjunctival autograft when the adjunctive use of a subconjunctival graft of amniotic membrane is employed to reduce fibrosis and recurrence after surgery. DESIGN: This is a retrospective, noncomparative study of postoperative outcomes. PARTICIPANTS: Eighty-four patients totalling 101 eyes with clinically significant pterygia that warranted surgical excision. METHODS: Surgeries were performed at South Orange County Outpatient Surgery Center (San Clemente, Calif.) between June 6, 2006, and October 23, 2013, by a single surgeon (J.A.H.). Patients were included in the study according to the need for pterygium surgery and the type of surgery performed. Exclusion criteria included patients with recurrent pterygium, those with pseudopterygium, and those whose treatment plan included prophylactic mitomycin during or after surgery. Initial pterygia measurements and postoperative findings were taken through standard slit-lamp examinations. RESULTS: Pterygium recurrence was defined as growth greater than 1 mm onto the corneal limbus at or after 6 months. There was 1 case of pterygium recurrence for a recurrence rate of 0.99% ± 1.93% (n = 101, p = 0.05). The mean extent of preoperative horizontal encroachment of pterygium on the cornea was 2.4 ± 0.87 mm. CONCLUSIONS: Pterygium excision with a conjunctival autograft and prophylactic placement of a subconjunctival amniotic membrane graft has a low recurrence rate with minimal added surgical time and minimal added risk to the patient and has merit as a surgical technique.