RESUMO
Proton magnetic resonance spectroscopy (1H MRS) non-invasively provides information on the biochemical profile (typically including up to nine metabolites and mobile lipids) of brain tissue, which varies according to the underlying disease process. A number of studies have assessed its accuracy in the diagnosis of adult brain tumours. This article describes the basic principles of 1H MRS, the metabolic profiles of different brain tumours, and practical points to aid interpretation of spectra. The literature is reviewed regarding the role of 1H MRS in the diagnosis of brain tumours and more specifically where it has proven to be of additional benefit over conventional magnetic resonance imaging.
Assuntos
Neoplasias Encefálicas/diagnóstico , Espectroscopia de Ressonância Magnética/métodos , Adulto , Astrocitoma/diagnóstico , Astrocitoma/metabolismo , Biópsia , Encéfalo/metabolismo , Encéfalo/patologia , Encefalopatias/diagnóstico , Encefalopatias/metabolismo , Neoplasias Encefálicas/metabolismo , Neoplasias Encefálicas/secundário , Humanos , Neoplasias Meníngeas/diagnóstico , Neoplasias Meníngeas/metabolismo , Meningioma/diagnóstico , Meningioma/metabolismo , Neoplasias Neuroepiteliomatosas/diagnóstico , Neoplasias Neuroepiteliomatosas/metabolismo , PrótonsRESUMO
Intracranial and spinal haemangiopericytomas are uncommon, durally based tumours. They macroscopically resemble meningiomas but are distinct histologically, have a more aggressive natural history and require different management. We present a pictorial review illustrating the radiological manifestations of these tumours that will aid in their preoperative identification.
Assuntos
Angiografia Cerebral , Hemangiopericitoma/diagnóstico , Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética , Neoplasias Meníngeas/diagnóstico , Tomografia Computadorizada por Raios X , Adulto , Idoso , Encéfalo/patologia , Diagnóstico Diferencial , Dura-Máter/irrigação sanguínea , Dura-Máter/patologia , Seguimentos , Hemangiopericitoma/cirurgia , Humanos , Angiografia por Ressonância Magnética , Neoplasias Meníngeas/cirurgia , Pessoa de Meia-Idade , Invasividade Neoplásica , Recidiva Local de Neoplasia/diagnóstico , Recidiva Local de Neoplasia/cirurgia , Pericitos/patologia , Sensibilidade e Especificidade , Compressão da Medula Espinal/diagnóstico , Compressão da Medula Espinal/cirurgiaRESUMO
High-resolution computed tomography (HRCT) is being increasingly used in the diagnostic work-up of paediatric patients with large and small airways disease due to its ability to provide valuable information far beyond that of other non-invasive investigations. This article highlights the key HRCT appearances of a range of conditions involving the airways in children, and where relevant, the role of HRCT in assessment of disease severity and monitoring of disease progression.