A bélelokészítés lehetoségei és hazai gyakorlata a tervezett colorectalis mutétek elott.

Introduction: The bowel preparation before elective colorectal surgery is a controversial topic in the surgical practice. During the last 15 years numerous publications concerning the necessity and options of the bowel preparation were published. The aim of our team was to perform a survey about the current, domestic practice as well as to give a short overview of the relevant literature and recommendations. Methods: 50 surgical departments performing colorectal surgeries routinely were asked to fill out an online, anonymous survey. The data of the survey filled out by 40 surgical departments were analyzed separately for the surgeries of the right colon, the left colon, and the rectum. Results: Based on the results, there is a high heterogeneity concerning the mode of the bowel preparation: in case of the right colon 7 different combinations, in case of the left colon and rectum 3-3 different combinations of bowel preparation methods are used. Conclusions: In the current domestic practice there is a high heterogeneity regarding the modes of the bowel preparation before the elective colorectal surgery, which are presumably based mainly on individual experience. The methods of the bowel preparation used by the majority of the surgical centers are not in accordance with the current international recommendations. A preparation of a Hungarian consensus document in this topic would be beneficial.

The effect of preoperative biliary stent on postoperative complications after the resection of pancreatic head tumour / A preoperatív biliáris sztent hatása a posztoperatív szövodményekre hasnyálmirigyfej-daganat miatt végzett reszekciós mutéteink kapcsán

Introduction. A preoperative biliary stent is often inserted because of obstructive jaundice due to pancreatic head tumour. However, it can also be the source of complications too. Aim and method. We retrospectively analyzed our operations which were performed between 01.10.2017 and 31.12.2019 for pancreatic tumour in association with stent related mortality and morbidity. The multiresistant bacteria and the spectrum of microorganism of intraoperative bile samples were investigated. Results. 82 patients were operated on with pancreatic tumour. There were 63 pancreatic head resections, and 19 palliative operations. 63 pancreatic head resections were analyzed. There were 36 open and 27 laparoscopic operations. Extended operation was needed in 12 cases (5 portal vein resections, 2 splenectomies, 1 right hepatolobectomy, 1 right hemicolectomy, 2 liver metastasectomies and 1 hepatic artery resection). The average age of 36 stented patients of which 24 were men and 12 women were 65 and 64 years respectively. The average age of 27 non-stented patients of which 14 were men and 13 were women, were 67.9 and 58 years respectively. The bile culture proved to be positive 30/36(83%) in the stented group and 13/27(48%) in the non-stented group (P = 0.005). The 3 most common bacteria were E coli, Enterococcus fecalis and Klebsiella pneumoniae in both groups followed by the yeast of Candida. 8 multiresistant bacteria were noticed in the stented group. 6 were ESBL producing (P = 0.033) and 2 vancomycine resistant (P = 0.5) bacteria. 3 patients of the stented group and 2 patients of the non-stented group were lost during the first 30 days. There were 4/0 wound infections, 6/2 haemorrhages, 2/2 pancreatic fistulas, and 2/3 abdominal abscesses in the stented vs. non stented groups. The average length of stay was 19.47 days in the stented and 14.62 days in the non-stented groups (P = 0.14). Conclusion. With regard to the fact that biliary stent changes the bacterial flora it is important to choose the proper antibiotic prophylaxis to reduce morbidity. On the basis of our own results and the literature an effective antibiotic therapy is suggested against enterococcus and ESBL producing bacteria. The prophylaxis against yeast in particularly in immunocompromised cases should also be considered. Regular antibiotic resistance check-up is essential.

Successful treatment of brachial artery aneurysm causing embolization after brachiocephalic arteriovenous fistula / Brachiocephalicus arteriovenosus fistula után kialakult embolizációt okozó arteria brachialis aneurysma sikeres kezelése

Introduction: The brachial artery aneurysm is a rare condition that accounts for 5% of peripheral aneurysms. Most are pseudoaneurysms that develop as a result of iatrogenic exposure or trauma. True brachial aneurysm can develop after an occluded dialysis fistula. The causes leading to this development are unclear, but steroid-containing and immunosuppressive drugs used after kidney transplantation, as well as increased flow during fistula function and increased mechanical effects on the vessel wall, may play a role. The authors report the case of a 43-year-old patient who underwent two kidney transplants and was hospitalized for acute left arm ischemia. Imaging studies (angiography, CT angiography) confirmed left brachial aneurysm and dilatation of the thrombotic venous stem of the previous brachiocephalic arteriovenous (AV) fistula, and peripheral embolization. The patient was successfully treated in our hospital with the involvement of several subspecialties. The outflow pathway was opened by minimally invasive catheter thrombolysis, the source of embolism was eliminated by conventional vascular surgery, aneurysm ligation, resection of occluded dilated venous stem, and autologous venous saphenous bypass. By describing the case, the authors would like to draw attention to the complex mindset leading to successful treatment.

Actinomycosis mimicking urachal cancer / Urachustumort utánzó hasi actinomycosis

Összefoglaló. Az urachus tumorai és egyéb betegségei ritkák. A 67 éves férfi anamnézisében ismétlodo húgyúti fertozés szerepelt ciprofloxacinterápiával. Cisztoszkópia során a húgyhólyag felso részének másodlagos érintettségére utaló bullosus nyálkahártya képe mutatkozott. Az ezt követo CT-felvételek alapján az alsó medián hasfallal, húgyhólyaggal, belekkel összefüggo tumor iránydiagnózisát állították fel. A kivizsgálás során kialakuló ileus miatt Hartmann-mutétet végeztek, a tumoros jellegu elváltozás teljes és az érintett szervek részleges eltávolításával. A kórszövettani vizsgálat daganatos elváltozást nem talált, hasi, vélhetoen urachuseredetu actinomycosist igazolt: erre az eredetre a lokalizáció és a tünetek közt szereplo köldökváladékozás alapján lehetett gondolni, annak ellenére, hogy urachusmaradványt szövettanilag nem sikerült igazolni a mikroabszcedáló gyulladás által érintett szövetekben. A betegnél amoxicillinterápia indult. Átmeneti, hólyag melletti vizeletcsorgást követoen a beteg tünet- és panaszmentesen távozott a kórházból, de 13 nappal késobb a hasfali seb sterilnek véleményezett szétválása miatt ismét hospitalizálni kellett. Negatív nyomású sebkezelést követoen sikerült a hasat ismét zárni. A beteg ismét tünetmentessé vált, és fenntartott antibiotikumkezelés mellett hagyta el a kórházat. Az urachuskörnyéki tumorszeru elváltozások között az actinomycosis lehetoségét is szem elott kell tartani a differenciáldiagnosztikában. Orv Hetil. 2022; 163(4): 157-160. Summary. Tumours and other diseases of the urachus are rare. A 67-year-old male presented with a history of recurrent urinary tract infection and ciprofloxacin therapy. Cystoscopy suggested secondary involvement of the bullous upper bladder wall. The subsequent CT-based diagnosis was of a tumour infiltrating the lower median abdominal wall, the urinary bladder and bowels. Bowel obstruction developed and this led to partial resection of the involved organs along with a Hartmann's procedure. Histology revealed no neoplastic conditions, but proved abdominal actinomycosis of probable urachal origin based on the location of the tumour-like lesion and umbilical discharge among the symptoms. Urachal remnants were not identified in the perivesical tissues involved by the microabscess forming inflammation. Amoxicillin therapy was initiated. After a temporary urine leakage from the bladder, the patient became symptomless and was emitted from hospital. After 13 days, he was readmitted because of abdominal wound disruption, which was treated with negative-pressure wound therapy before the abdomen could be closed. At the time of reporting, he is still on amoxicillin, and has become symptomless again. Actinomycosis should be considered in the differential diagnosis of mass lesions of the urachal region. Orv Hetil. 2022; 163(4): 157-160.

Readmission indicated by severe fluid-electrolyte disturbances as a complication of ileostomy / A kórházi visszavételt igénylo súlyos folyadék-elektrolit zavar mint az ileosztóma egyik szövodménye

Introduction: After the operations of rectal tumours following neoadjuvant chemo-radio therapy it is a common practice to create a defunctioning ileostomy in order to prevent complications due to anastomotic leak. The ileostomy itself can be the source of complications with 20­60% incidence rate, while dehydration causes 16.9­40% of readmissions. Aims: Our goal was to review our own cases on the basis of complications of ileostomy particularly with regard to dehydration and its consequences. We wanted to develop a therapeutic protocol to help prevent these severe complications. Results: We retrospectively analyzed the morbidity data of our patients who had defunctioning ileostomy for different indications between 01.09.2017­31.12.2019. During this period, 252 rectosigmoid resections and 33 abdominoperineal resections of the rectum were performed. Ileostomy was created for 110 patients. 27 patients (24.5%) were readmitted with severe renal impairment and electrolyte disturbances. 24 patients were readmitted once, 1 patient twice and 2 patients 3 times. Readmission happened an average of 49.6 days (1­343) after the operation. At admission and readmission the average of GFR (glomerular filtration rate) of patients was 54.66 (38­60) ml/min/1.73 m2 ­ 22.8 (5­51) ml/min/1.73 m2 (p = 0.001), the average of serum Na level was 140.7 (133­145) mmol/l ­ 131.4 (111­144) mmol/l (p = 0.001), the average of serum K level was 4.6 (3.2­5.6) mmol/l ­ 5.37 (3.6­7.6) mmol/l (p = 0.005) and the average of serum creatinine level was 89.6 (54­149) µmol/l ­ 33.3 (107­877) µmol/l (p = 0.001). Conclusion: With regard to the short and long term severe complications of dehydration and the high risk of readmission caused by ileostomy, it is important to estimate the risk of patients, to educate the inpatients as early as possible, to commence the prevention of dehydration, and regularly monitor in the outpatient setting. Provided the conditions are given, the early closure of ileostomy should be considered.

The role of indocyanine green fluorescence in sentinel lymph node biopsy for breast cancer / Az indociánzöld-fluoreszcencia hasznosítása az emlorák miatt végzett orszemnyirokcsomó-biopsziában.

Összefoglaló. Bevezetés: Napjainkban az orszemnyirokcsomó felkeresésének legelterjedtebb módszere a radioizotópos és kék festékes kettos jelölés, emellett azonban több más jelölés is alkalmazható. Az indociánzöld-fluoreszcencia ígéretes nyirokút-térképezési módszer, mely a találati arányát tekintve - irodalmi adatok alapján - összevetheto a radioizotópos módszerrel. Módszer: Osztályunkon 2020. 03. 31. és 2020. 04. 15. között 10, emlorák miatt operált betegünknél alkalmaztuk az indociánzöld és a kék festékes kettos jelölés módszerét az orszemnyirokcsomó felkeresésére. Eredmények: A 10 operált betegünknél összesen 17 orszemnyirokcsomót azonosítottunk és távolítottunk el. 16 orszemnyirokcsomó jól festodött indociánzölddel (találati arány: 0,94; 95%-os konfidenciaintervallum [CI ]: 0,73-0,99), míg kék festékkel 9 jelölodött (találati arány: 0,53; 95%-os CI: 0,31-0,74). A szövettani feldolgozás során összesen 2 orszemnyirokcsomó bizonyult áttétesnek, ezek közül 1 kék és fluoreszcens volt, 1 pedig csak kék festékkel jelölodött. Következtetés: Kezdeti, kis esetszámnál nyert tapasztalataink alapján az indociánzöld jelölés emlorák során végzett orszemnyirokcsomó-biopszia esetén jól használható kettos jelölési módszer részeként, kék festékkel kiegészítve. A módszer találati aránya, valamint fals negatív aránya irodalmi adatok alapján nem különbözik szignifikánsan a radioizotópos jelölés módszerétol. Orv Hetil. 2021; 162(8): 293-297. INTRODUCTION: The current practice in sentinel lymph node biopsy for breast cancer is the radioisotope and blue dye dual labelling technique, however, other mapping methods are also available. Indocyanine green fluorescence is one of the best alternatives of the standard technique, with detection rates comparable to those of the radioisotope method. METHOD: Between 31. 03. 2020 and 15. 04. 2020, a total of 10 sentinel lymph node biopsies for breast cancer were performed using the indocyanine green fluorescence and blue dye dual technique. RESULTS: 17 sentinel lymph nodes were detected and removed in total, from which 16 showed explicit fluorescence activity (detection rate: 0.94; 95% confidence interval [CI]: 0.73-0.99), whilst 9 where blue (detection rate: 0.53; 95% CI: 0.31-0.74). During histopathological examination, 2 sentinel lymph nodes proved to be metastatic, from which 1 was fluorescent and blue, the other was blue only. CONCLUSION: Regarding our early experience based on a small number of patients, indocyanine green fluorescence, used together with blue dye as part of a dual technique, is a usable method for sentinel lymph node mapping. Based on data from the literature, the detection rate and the false-negative rate of the indocyanine green fluorescence method shows no significant difference from the radioisotope mapping technique. Orv Hetil. 2021; 162(8): 293-297.

The role of laparoscopy in the treatment of perforated gastro-duodenal ulcers / Laparoszkópia helye a gastro-duodenális fekélyperforációk ellátásában

Introduction: The incidence of peptic ulcer disease decreased due to proton pump inhibitors and Helicobacter pylori eradication. Bleeding from peptic ulcer decreased, as well, although perforation did not decrease and it is permanently between 2­10%. This is a potential surgical emergency, the mortality can reach up to 25% and the morbidity 50%, respectively. Urgent surgical intervention in the right time can improve the results. Aim: To compare the morbidity, mortality, the length of hospital stay and duration of operating time in open and laparoscopic repair of perforated peptic ulcer. Results: A cohort of 55 patients were operated on with perforated peptic ulcer from 01.01.2017 to 30.06.2019 31 open (51.36%) and 24 laparoscopic (43.63%) operations were performed from which 4 (16.6%) needed conversion to open approach. The average age of 23 men and 8 women were 56.3 and 70.3 years respectively in the open operations group, while 13 men and 11 women with average age of 49.7 and 53.7 years was in the laparoscopic operations group. Within 30 days the number of complications were 5 in the open and 2 in the laparoscopic group (p = 0.45). The average duration of operation was 51.95 minutes (30­85) in the open and 63.41 minutes (25­110) in the laparoscopic group (p = 0.13). 6 from the open group with average age of 74.3 years and 2 from the laparoscopic group with average age of 68.5 years died within 30 days (p = 0.44). The average length of stay was 7.13 (5­16) days in the open and 6.19 (4­13) days in the laparoscopic group (p = 0.24). The average size of the perforation was 7.4 mm (3­20) in the open and 5.3 mm (3­10) in the laparoscopic group (p = 0.14). Free air was seen in the abdominal cavity in 25 cases (80%) of the open and in 11 cases (54%) of the laparoscopic group. Conclusion: Early diagnosis, prompt supportive care and antibiotic treatment and urgent surgical intervention are essential to improve outcomes. The standard operation is the simple suture with pedicled omental flap which can be performed by either open or laparoscopic surgical repair. Laparoscopic method spreads slowly, the learning curve is longer and it needs more expertise but the morbidity is lower than that of the open surgery. The morbidity does not increase after conversion according to the literature so if there is no contraindication and there is enough expertise it should be suggested as the first choice.

Comparing the short-term results of extracorporeal and intracorporeal anastomosis in laparoscopic right hemicolectomy performed because of malignant tumour / Extrakorporális és intrakorporális anasztomózis rövid távú eredményeinek összehasonlítása malignus daganat miatt végzett laparoszkópos jobb oldali hemikolektómia esetén

Introduction: Laparoscopy became evident for right-sided colon surgery too. Today the laparoscopic-assisted right-hemicolectomy is the gold standard with extracorporeal anastomosis. Morbidity according to randomized trials is still approximately 30%. The development of the surgical technique resulted in the creation of intracorporeal anastomosis. Our aim was to compare the short-term results of the two methods. Aim: To analyse the short-term results of right-sided hemicolectomy that were performed due to malignant tumours with the comparison of the two methods. Results: A cohort of 184 right-sided hemicolectomy were performed from 01.01.2018 to 31.12.2019 from which 122 were operated on because of a malignant disease. 51 open and 71 laparoscopic operations were performed. The average age of 37 men and 34 women were 70.59 and 72.14 years, respectively. 50 patients underwent extracorporeal (EA) anastomosis and 21 intracorporeal (IA) anastomosis. Within 30 days the number of complications were 18 in the EA group and 3 in the IA group (p = 0.067). 3 from the EA group and 1 from IA group died within 30 days (p = 0.66). The average length of stay were 9.48 days in the EA group and 6.52 days in the IA group together with the complicated cases (p = 0.001) while 6.35 days and 5.55 days without the complicated cases (p = 0.09). The average duration of operation was 147 minutes in the EA and 146.47 minutes in the IA group (p = 0.11). Conclusion: We found concordance with the literature that there are fewer complications in case of IA which might be related to shorter length of stay. There is no significant difference between the surgical times. Bearing these facts in mind, IA might be suggested for right- sided laparoscopic hemicolectomy.

The results of the first 100 minimal invasive lobectomy in our department / Az elso száz minimálisan invazív tüdolebeny-eltávolítás eredményei osztályunk beteganyagában

Patients and methods: Between 1st November 2013 and 30th June 2019 we performed 112 VATS lobectomies with isolated intubation and anterior approach. In 98 cases lobectomies were performed for malignant lesions, while in 9 cases for benign changes. 78 men and 34 women were operated on. The average age was 60.5 years (42­63). In 5 cases the left upper lobes were resected, in cases 36 the left lower lobes, in 15 cases the right upper lobes, in 11 cases the mid lobes, in 44 cases the right lower lobes, and in one case pneumonectomy was performed. Results: there was no postoperative mortality. Conversion was required in three 3 patients. The average time of surgery was 150 minutes (70­215). Re-operation was needed in two cases due to bleeding and air leakage. Out of the 112 operations, primary lung cancer was demonstrated on pathology in 88 cases, while benign lesions /inflammation in 9 cases. The stages of primary lung cancer were the following: I.a:57, I.b:22, II.a:6, II.b:3 patients. Tumour subtypes were the detailed as 52 adenocarcinoma, 23 squamous cell cc., 2 small cell cc., 5 large cell cc., and 6 carcinoid. 10 patients underwent VATS lobectomy for metastatic disease. Conclusion: As a result of an adequate learning period, VATS lobectomies have become a routine surgery in our unit. Currently 65% of the thoracotomies and more than 50 percent of the lobectomies are performed by the VATS method. Our results are comparable to national as well as international data.

[The importance of the extracapsular extension of the sentinel node metastasis in the surgical treatment of breast cancer]. / Az orszemnyirokcsomó extracapsularis áttétének jelentosége az emlorák sebészi kezelésében.

Introduction: The introduction of sentinel node biopsy (SNB) has led to a significant decrease of axillary lymph node dissections (ALND). The importance of the extracapsular extension (ECE) in the sentinel lymph node (SN) remains unclear. Method: The data of 635 patients with T1-T2N0M0 invasive breast cancer who underwent SNB between 2014 and 2018 were retrospectively analysed. 25% of the SNB patients (158) had metastasis in the SNs. These patients were grouped based on the presence or absence of ECE. The main objective of our study was to analyse the occurrence of massive (>3) node metastasis in the case of ECE negative and ECE positive patients, where ALND was performed. Results: There were 91/158 patients (58%) in the ECE negative group and 67/158 patients (42%) in the ECE positive group. ALND was performed in 42% of the ECE negative and in 69% of the ECE positive patients. There were no significant differences in the mean age of the patients; size, histological type and grade of the tumours, presence of lymphovascular invasion and proportion of hormone and HER2 receptor positivities. In the ECE negative ALND group, pN1 involvement was 82%, pN2+pN3 involvement represented 18% of cases. In the ECE positive ALND group, pN1 involvement was 60%, pN2+pN3 involvement was found in 40% of cases. The presence of ECE was associated with greater axillary disease burden. These results show a significant difference (p = 0.038). Conclusions: ECE of the SN is an important predictor for non-sentinel lymph node involvement. These data suggest, when ECE is confirmed, it is a further factor to be considered in deciding about ALND.

[Laparoscopic and open complete mesocolic excision in right-sided colon cancer compared with open and laparoscopic surgery]. / Laparoszkópos és nyitott komplett mezokólikus excízió összehasonlítása nyitott és laparoszkópos konvencionális mutéttel jobb oldali vastagbéldaganatoknál ­ retrospektív feldolgozás, kezdeti tapasztalatok.

Introduction: In 2009, Hohenberger translated the concept of total mesorectal excision to colon cancer surgery and he named it complete mesocolic excision (CME). The principle of CME is based on wide mesenteric excision in the embriologic plane to remove mesenteric lymph nodes, central vascular ligation without damage of the peritoneal layer. CME can be performed by laparoscopic and open methods. Aim: To make sure that we are capable of performing right laparoscopic hemicolectomy with similar results to the open method. Results: A cohort of 156 consecutive patients were operated on with malignant right-sided colon tumours from 01.09.2016 to 30.06.2019. 143 curative resections were performed in 63 men and 80 women. The average age of men and women were 71.5 and 72.75 years, respectively. 84 laparoscopic and 59 open operations were performed. 84 patients underwent CME surgery and 56 conventional resections. The average length of the specimen was 22.34 cm in the conventional and 24.97 cm in CME surgery (p = 0.18) and the average lymph node number were 15.4 and 16.9, respectively (p = 0.24). The average duration of the operation was 111 minutes for the conventional and 136 minutes for the CME group (p = 0.0014), while the average length of stay were 7.47 days and 5.65 days (p = 0.0004) respectively for the cases without complications. Conclusion: We are yet in the learning period, but based on the early results, it might be concluded that the operation can be performed by laparoscopic methods as well with similar results to the open operation but with shorter length of stay.

[The comparison of open and laparoscopic surgeries of the locally advanced chemo-irradiated rectum tumours]. / Lokálisan elorehaladott kemoirradiált rectumtumorok nyitott és laparoszkópos mutéteinek az összehasonlítása.

Introduction: The raison d'etre of laparoscopic surgery of colonic tumours is supported by many I/a level evidence. There are a lot of excellent early and late results regarding sigmoid and upper third rectum tumours in favour of laparoscopic surgery. There are not many literature proposals like this regarding chemo-irradiated tumours. Material and method: One hundred ninety-six patients received neoadjuvant treatment due to lower and middle third rectum tumours in the Borsod-Abaúj-Zemplén County Hospital between the 1st of January 2006 and the 31st of December 2011. Twelve patients out the 196 were not followed up, so we analysed 184 patients' data. We performed laparoscopic surgery on 67 patients. Conversion happened on 15 patients out of the 67 cases. Open surgery was performed on 117 patients. We strived for the ligation of the inferior mesenteric artery at the origin, the sparing of the autonomic nerves and the precise implementation of TME. The splenic flexure has been taken down during the operations that involved resection. Results: The Dukes stages as well as the, ASA stages were similar in both groups. There was no significant difference in the patients' BMI either. The length of the removed specimens and the tumour size were similar too. The defining factors of recurrence are the involvement of the circumferential resection margin (CRM) and the complete execution of the TME. These were appropriate in our laparoscopic cases, and we did not find a significant difference in between the groups (Chi-square test, p = 0.94). The operation time was similar in the laparoscopic, converted and open surgeries, and there was no significant difference either. The shortest postoperative care time was in the laparoscopic group, but the Mann-Whitney test did not reveal a significant difference. Similarly to literature data, we experienced much less wound-related complications like infections and fever in the laparoscopic group. There was a significant difference in terms of transfusion demand comparing the laparoscopic and open operation groups, to the detriment of the open surgery group (Chi-square test, p = 0.04). We did not find a significant difference in recurrence or survival during follow-up of the patients. Conclusion: In addition to the short-term advantages of laparoscopic surgery, it is a safe procedure for the chemo-irradiated rectum tumours even from an oncological point of view. Both open and laparoscopic surgery requires high-level competency and qualification and these must be performed in centres.

Negative pressure wound therapy of Corynebacterium jeikeium associated granulomatous mastitis.

We present the first Corynebacterium associated therapy resistant granulomatous mastitis successfully treated with negative pressure wound therapy (NPWT). Our patient had received five different courses of antibiotic therapy, and three surgical explorations before NPWT was introduced and resulted in healing. For a successful treatment, the use of targeted antibiotic therapy, steroid therapy and in case of progressive disease, wide excision is required. When this results in a large wound cavity, NPWT seems an effective and innovative option.

[Outcomes following rectal and recto-sigmoid cancer resections: comparison of the laparoscopic and open techniques]. / Rectum- és rectosigmoidealis tumorresectiók eredményei: a laparoscopos és nyitott technika összehasonlítása.

BACKGROUND/AIMS: Surgical technique and experience are considered as significant determinants of the successful treatment of recto-sigmoid malignancies. METHODS: Two hundred patients operated on between 2005 and 2009 were prospectively followed with an average of 39.8 months. Patients with rectosigmoid or rectal cancer were included, either with primary resection or resection after neoadjuvant therapy. The primary aim was to assess the average survival in the two groups; secondary outcomes were stage specific survival and the incidence of loco-regional recurrence and distant metastases. Intra- and postoperative complications, operating time, onco-pathological specimen quality and length of stay were also analysed. RESULTS: During the follow-up comparable rates for 3-year survival and recurrence rates were found without statistical difference. Hospital stay in the laparoscopic group was significantly shorter and the mid-term survival rates were also better in the more advanced stages. Incisional hernia rate was significantly lower in the laparoscopic group. CONCLUSIONS: The results of laparoscopic rectal and recto-sigmoid resections were not inferior, and - in some aspects - they were even better compared to open procedures. Adding the properties of the minimally invasive technique (shorter recovery, reduced surgical stress reaction) this should be the preferred method of operative approach.

[Laparoscopic sigmoid resection in total situs inversus]. / Laparoscopos sigmaresectio situs inversus totalisban.

Total situs inversus (SIT) is a rare congenital disorder in which all abdominal and thoracic organs are in reversed position. A 57-year-old man with SIT presented with change in bowel habits and rectal bleeding.Colonoscopy and abdomino-pelvic CT scan confirmed a constricting sigmoid lesion with normal tumor-marker levels. In our department the elective laparoscopic colon resection with lymphadenectomy is the preferred alternative of open surgery and is the chosen method in about 60 percent of cases. This is the first documented case report in Hungarian of a laparoscopically resected sigmoid tumour in a patient with SIT. We believe that with appropriate knowledge of anatomy and advanced routine in laparoscopic surgery laparoscopic resection can be a safe method even in a special case like this one was.

Impact of positive intraabdominal lavage cytology on the long-term prognosis of colorectal cancer patients.

BACKGROUND: Our aim was to investigate the presence of free cancer cells found in lavage cytology specimens taken from the proximity of tumors during the course of curative open and laparoscopic colorectal resections and then examine and compare the long-term disease outcomes in cases of negative and positive cytology. Based on the results, we were hoping to identify the place of peritumoral lavage cytology among prognostic factors for disease recurrence. METHODS: Between January 1, 2005 and December 31, 2007 intraoperative peritoneal lavage cytology was performed in 145 patients who underwent curative colorectal procedures. In all, 37 of the procedures were laparoscopic resections. RESULTS: Malignant cells were detected in the intraoperative peritoneal lavage cytology samples from 25 patients. Median follow-up was 47 months (3-81 months). Among the 25 patients with positive cytology; locoregional recurrence or distant metastasis was found in 14 during this period (56 %), whereas among the 120 patients with negative cytology the incidence was 28 (23 %). CONCLUSIONS: The impact of tumor stage, lymph node status, and peritoneal lavage cytology on recurrence rates is significant. Tumor, nodal, and lavage cytology status can be organized hierarchically in relation to time of recurrence. Cytology is most important, with positivity rendering long-term prognosis unfavorable. When comparing surgical techniques (open versus laparoscopic), we found no significant difference in recurrence rates. Our study has shown that conventional peritoneal lavage cytology is a prognostic factor in the case of patients undergoing curative colorectal operations.

[Colon cancer after colon interposition for oesophageal replacement]. / Colonnal történt nyelocsopótlás után kialakult vastagbél-adenocarcinoma.

The authors report the case of a colon adenocarcinoma developed on the neck at the anastomosis of the skin tube and colon 44 years following a corrosive oesophageal injury. This patient suffered a moderately severe oesophageal, stomach and laryngeal injuries due to drinking hydrochloric acid 44 years ago. He underwent serial laryngoplasties, then needed a tracheostomy, oesophagectomy, pyloroplasty and ileocolon transposition. An antethoracal oesophagus formation was performed with ileocolon and skin tube amendment. 44 years later an ulcerated adenocarcinoma developed in the transposed colon, which was resected and the ability to swallow was reinstated by the transplantation of an isolated jejunal segment using microvascular anastomosis.

[Laparoscopic treatment of appendiceal mucocele]. / Appendix mucokele laparoscopes mûtéti megoldása.

Mucocele is a mucin-filled cavity, which can be multi-loculated as well. Mucocele is relatively rarely found in the appendix. The disease does not cause any symptoms in most cases, and it is usually an accidental finding. A thorough investigation should be carried out to exclude malignancy. Depending on the operative findings and the full histological report, the spectrum of surgery extends from appendectomy to right hemicolectomy. In this paper, we discuss the presentation, diagnostical options, and the possible surgical treatment--based on our experience with five cases. In three cases a non-tender mass was palpable in the right lower quadrant of the abdomen, while another patient presented with right lower quadrant abdominal pain and one with abdominal pain and diarrhoea. Abdominal and pelvic ultrasound and CT scans raised the possibility of mucocele, however colonoscopy was negative. After laparoscopic exploration, laparoscopy assisted partial caecum resection was carried out in two cases, in further two cases laparoscopic appendectomy, and in one case laparoscopic partial caecum resection was done. The hystological examinations showed appendiceal mucocele with no malignancy demonstrated. All patients recovered without complications, they were discharged from hospital on postoperative day five. The patients have been disease free after a 6-30 month follow-up period. We concluded that laparoscopy is a recommended method for the surgery of appendiceal mucocele.