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1.
Z Gerontol Geriatr ; 57(4): 315-320, 2024 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-38772928

RESUMO

This case report details the assessment and interdisciplinary collaboration in the management of an 81-year-old patient presenting with acute visual impairment, dizziness, general weakness, gait disturbances and fear of falling. A holistic geriatric evaluation revealed orthostatic dysregulation and an underlying multifactorial gait disorder exacerbated by visual impairment. Ophthalmological findings included left central retinal artery branch occlusion and cataracts. A comprehensive geriatric assessment showed frailty, impaired mobility and decreased functional abilities. Subsequent patient-centered interdisciplinary approaches included treatment for retinal ischemia, orthostatic testing, medication reconciliation, physiotherapy and occupational therapy. This case emphasizes how interdisciplinary collaboration between ophthalmology and geriatrics enables proactive assessment and intervention to reduce the risk of functional decline and loss of autonomy in visually impaired patients, which is of particular relevance considering the increasing prevalence of visual impairment in the ageing population.


Assuntos
Avaliação Geriátrica , Humanos , Idoso de 80 Anos ou mais , Colaboração Intersetorial , Masculino , Transtornos da Visão/diagnóstico , Transtornos da Visão/etiologia , Equipe de Assistência ao Paciente , Feminino , Comunicação Interdisciplinar , Oftalmologia , Acidentes por Quedas/prevenção & controle , Reconciliação de Medicamentos , Catarata/terapia , Catarata/diagnóstico , Catarata/complicações
2.
Med Klin Intensivmed Notfmed ; 119(Suppl 1): 1-50, 2024 May.
Artigo em Alemão | MEDLINE | ID: mdl-38625382

RESUMO

In Germany, physicians qualify for emergency medicine by combining a specialty medical training-e.g. internal medicine-with advanced training in emergency medicine according to the statutes of the State Chambers of Physicians largely based upon the Guideline Regulations on Specialty Training of the German Medical Association. Internal medicine and their associated subspecialities represent an important column of emergency medicine. For the internal medicine aspects of emergency medicine, this curriculum presents an overview of knowledge, skills (competence levels I-III) as well as behaviours and attitudes allowing for the best treatment of patients. These include general aspects (structure and process quality, primary diagnostics and therapy as well as indication for subsequent treatment; resuscitation room management; diagnostics and monitoring; general therapeutic measures; hygiene measures; and pharmacotherapy) and also specific aspects concerning angiology, endocrinology, diabetology and metabolism, gastroenterology, geriatric medicine, hematology and oncology, infectiology, cardiology, nephrology, palliative care, pneumology, rheumatology and toxicology. Publications focussing on contents of advanced training are quoted in order to support this concept. The curriculum has primarily been written for internists for their advanced emergency training, but it may generally show practising emergency physicians the broad spectrum of internal medicine diseases or comorbidities presented by patients attending the emergency department.


Assuntos
Currículo , Medicina de Emergência , Serviço Hospitalar de Emergência , Medicina Interna , Medicina Interna/educação , Humanos , Alemanha , Medicina de Emergência/educação , Competência Clínica , Educação de Pós-Graduação em Medicina
3.
Z Gerontol Geriatr ; 55(1): 44-50, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34351482

RESUMO

OBJECTIVE: Since 1996, older patients have been treated in the Nuremberg Geriatric Day Hospital. The geriatric depression scale (GDS) is an obligatory part of the geriatric assessment at admission but its use in the clinical setting has revealed some problems. The aim of the study was to compare the GDS with the depression in old age scale (DIA-S) in terms of applicability and psychometric characteristics. METHODS: As gold standard a semi-structured interview was used to record the depression criteria according to Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Using a sample of 375 patients, sensitivity and specificity as well as positive and negative predictive values were calculated for both screening tests. RESULTS: No clear superiority of any screening method could be proven. The sensitivity of the DIA­S in the overall sample was higher than that of the GDS, but the specificity was much lower. In terms of predictive values, there were slight advantages for the GDS. In the sub-samples, poorer values were found in both scales for cognitively impaired or dementia patients with slightly better values for GDS. CONCLUSION: The DIA­S can be used very easily in everyday clinical practice, but no advantages of this method compared to GDS could be demonstrated.


Assuntos
Depressão , Avaliação Geriátrica , Idoso , Depressão/diagnóstico , Depressão/epidemiologia , Humanos , Programas de Rastreamento , Escalas de Graduação Psiquiátrica , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Aging Clin Exp Res ; 34(2): 455-463, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34275114

RESUMO

BACKGROUND: Polypharmacy is becoming increasingly common and all doctors must be prepared to manage it competently. AIMS: The aim of this project is to evaluate the feasibility and use of a novel gamification-based teaching intervention on polypharmacy among doctors undergoing advanced geriatric training. Among others, one of the learning goals for the students was to be able to describe the adherence to medication. METHODS: Electronic questionnaire sent to students of the third session "evidence-based medicine in geriatrics" of advanced postgraduate course in geriatrics of the European Academy for Medicine of Ageing. RESULTS: Most students reported issues with forgetting doses and remembering sufficiently to establish a medication routine due to busy schedules as well as social influences around medication taking. Reflecting on the challenges of the game, most students reported that their own prescribing practice was likely to change. DISCUSSION AND CONCLUSION: The current model of learning appears to be a feasible approach for postgraduate medical education or in other areas of healthcare such as nursing or physiotherapy. Learning through action and reflection promotes deeper thinking and can lead to behavioral change, in this case thus enhancing the attitudes and understanding regarding pharmacological issues associated with ageing. Recommendations for future research in medical education about medication adherence are outlined.


Assuntos
Gamificação , Geriatria , Idoso , Envelhecimento , Currículo , Geriatria/educação , Humanos , Aprendizagem , Inquéritos e Questionários , Ensino
5.
Eur Geriatr Med ; 12(4): 817-824, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33523375

RESUMO

PURPOSE: Integration of palliative care competencies with geriatric medicine is important for quality of care for older people, especially in the last years of their life. Therefore, knowledge and skills about palliative care for older people should be mandatory for geriatricians. The European Geriatric Medicine Society (EuGMS) has launched a postgraduate curriculum for geriatric medicine recently. AIM: Based on this work, the Special Interest Group (SIG) on Palliative care in collaboration with the SIG in Education and Training aimed to develop a set of specific palliative care competencies to be recommended for training at a postgraduate level. METHODS: Competencies were defined using a modified Delphi technique based upon a Likert like rating scale. A template to kick off the first round and including 46 items was developed based on pre-existing competencies developed in Switzerland and Belgium. RESULTS: Three Delphi rounds were necessary to achieve full consensus. Experts came from 12 EU countries. In the first round, the wording of 13 competencies and the content of 10 competencies were modified. We deleted or merged ten competencies, mainly because they were not specific enough. At the end of the 2nd round, one competence was deleted and for three questions the wordings were modified. These modifications had the agreement of the participants during the last round. CONCLUSION: A list of 35 palliative care competencies for geriatricians is now available for implementation in European countries.


Assuntos
Geriatras , Cuidados Paliativos , Idoso , Consenso , Currículo , Técnica Delphi , Humanos
6.
Scand J Trauma Resusc Emerg Med ; 28(1): 68, 2020 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-32678052

RESUMO

INTRODUCTION: In emergency care, geriatric requirements and risks are often not taken sufficiently into account. In addition, there are neither evidence-based recommendations nor scientifically developed quality indicators (QI) for geriatric emergency care in German emergency departments. As part of the GeriQ-ED© research project, quality indicators for geriatric emergency medicine in Germany have been developed using the QUALIFY-instruments. METHODS: Using a triangulation methodology, a) clinical experience-based quality aspects were identified and verified, b) research-based quality statements were formulated and assessed for relevance, and c) preliminary quality indicators were operationalized and evaluated in order to recommend a feasible set of final quality indicators. RESULTS: Initially, 41 quality statements were identified and assessed as relevant. Sixty-seven QI (33 process, 29 structure and 5 outcome indicators) were extrapolated and operationalised. In order to facilitate implementation into daily practice, the following five quality statements were defined as the GeriQ-ED© TOP 5: screening for delirium, taking a full medications history including an assessment of the indications, education of geriatric knowledge and skills to emergency staff, screening for patients with geriatric needs, and identification of patients with risk of falls/ recurrent falls. DISCUSSION: QIs are regarded as gold standard to measure, benchmark and improve emergency care. GeriQ-ED© QI focused on clinical experience- and research-based recommendations and describe for the first time a standard for geriatric emergency care in Germany. GeriQ-ED© TOP 5 should be implemented as a minimum standard in geriatric emergency care.


Assuntos
Medicina de Emergência/normas , Serviço Hospitalar de Emergência , Avaliação Geriátrica , Geriatria/normas , Indicadores de Qualidade em Assistência à Saúde , Acidentes por Quedas/prevenção & controle , Idoso , Delírio/diagnóstico , Técnica Delphi , Humanos , Capacitação em Serviço , Programas de Rastreamento/normas , Reconciliação de Medicamentos , Avaliação das Necessidades , Melhoria de Qualidade , Medição de Risco
7.
Z Gerontol Geriatr ; 51(2): 157-159, 2018 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-29242982

RESUMO

Anemia and chronic heart failure are frequent comorbidities in geriatric patients. In approximately one third of older adults the cause of the anemia is an iron, vitamin B12 and/or folate deficiency and in another third a chronic inflammatory process is present. In the case of iron deficiency a differentiation must be made between the absolute and functional forms. Although in functional iron deficiency ferritin, as a parameter of iron metabolism, is within the normal range or can even be higher, an iron-deficient erythropoiesis is present. In cardiac insufficiency a chronic inflammatory process is assumed. According to the recent guidelines of the Deutsche Gesellschaft für Kardiologie (DGK, German Cardiac Society) and European Society of Cardiology (ESC) a routine contol of the iron status should be performed and, if necessary, initiation of adequate supplementation is recommended.


Assuntos
Anemia Ferropriva/tratamento farmacológico , Insuficiência Cardíaca/tratamento farmacológico , Compostos de Ferro/uso terapêutico , Idoso , Anemia Ferropriva/sangue , Anemia Ferropriva/epidemiologia , Doença Crônica , Comorbidade , Estudos Transversais , Feminino , Compostos Férricos , Insuficiência Cardíaca/sangue , Insuficiência Cardíaca/epidemiologia , Hemoglobinometria , Humanos , Compostos de Ferro/efeitos adversos , Masculino , Maltose/análogos & derivados , Valores de Referência , Transferrina/metabolismo
8.
Arch Orthop Trauma Surg ; 136(1): 65-73, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26646844

RESUMO

INTRODUCTION: Research by AOTrauma's orthogeriatrics education taskforce identified ongoing educational needs for surgeons and trainees worldwide regarding the medical management of older adults with a fracture. To address practicing surgeons' preference for increased use of mobile learning, a point-of-care educational app was planned by a committee of experienced faculty. The goals were to deliver the app to surgeons, trainees, and other healthcare professionals, to measure usage, and to evaluate the impact on patient care. MATERIALS AND METHODS: The committee of geriatricians and surgeons designed and developed four modules on osteoporosis, delirium, anticoagulation, and pain based on published evidence and the content was programmed into mobile app formats. A registration form was integrated and a 14-question online evaluation survey was administered to users. RESULTS: The AOTrauma Orthogeriatrics app was installed by 17,839 users worldwide between September 2014 and October 2015: Android smartphones (44%), iPhones (32%), iPads (15%), Android tablets (9%). 920 users registered and 100 completed the online evaluation: orthopedic/trauma surgeons (67%), residents/fellows (20%), and other professionals (13%). Ratings for all aspects were 4 or higher on a 1-5 Likert scale (5 = Excellent). 80% of evaluation respondents found the answer to their question or educational need on their last visit, and 26 of 55 respondents (47%) reported making a change in an aspect of their management of patients as a result of their learning from the app. CONCLUSION: The orthogeriatrics app reached its intended audiences and was rated highly as a method of providing education to help improve patient care. Content input by experienced faculty and app improvements based on user feedback were key contributors to successful implementation.


Assuntos
Geriatria/educação , Serviços de Saúde para Idosos , Aplicativos Móveis , Ortopedia/educação , Sistemas Automatizados de Assistência Junto ao Leito , Adulto , Idoso , Idoso de 80 Anos ou mais , Atitude do Pessoal de Saúde , Tomada de Decisão Clínica , Feminino , Saúde Global , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Pesquisa Qualitativa , Qualidade da Assistência à Saúde , Estudos Retrospectivos
9.
Br J Nutr ; 113(12): 1940-50, 2015 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-25990706

RESUMO

We examined the relationship between postoperative dietary intake (DI) of geriatric hip fracture (HF) patients and their functional and clinical course until 6 months after hospital discharge. In eighty-eight HF patients ≥ 75 years, postoperative DI was estimated with plate diagrams of main meals over four postoperative days. DI was stratified as >50, >25-50, ≤ 25 % of meals served. Functional status according to Barthel index (activities of daily living) and patients' mobility level before fracture, postoperatively, at discharge and 6 months later were assessed and related to DI levels. In-hospital complications were recorded according to clinical diagnosis. Associations were evaluated using χ2 and Kruskal-Wallis tests, and repeated-measures ANOVA and ANCOVA. Postoperatively, 28 % of participants ate >50 %, 43 % ate >25-50 % and 28 % ≤ 25 % of meals served. Irrespective of pre-fracture functional status, patients with DI ≤ 25 % had significantly lower Barthel index scores at all times after surgery (all P50 % more often had regained their pre-fracture mobility level than those with DI ≤ 25 % at discharge (>50 %: 36 %; >25-50 %: 10 %; ≤ 25 %: 0 %; P= 0·001) and 6 months after discharge (88; 87; 68 %; P= 0·087) and had significantly less complications (median 2 (25th-75th percentile 1-3); 3 (25th-75th percentile 2-4); 3 (25th-75th percentile 3-4); P= 0·012). To conclude, geriatric HF patients had very low postoperative voluntary DI and thus need specific nutritional interventions to achieve adequate DI to support functional and clinical recovery.


Assuntos
Atividades Cotidianas , Dieta , Fraturas do Quadril/cirurgia , Quadril/fisiopatologia , Estado Nutricional/fisiologia , Idoso , Idoso de 80 Anos ou mais , Comorbidade , Ingestão de Alimentos , Feminino , Fraturas do Quadril/fisiopatologia , Fraturas do Quadril/reabilitação , Humanos , Tempo de Internação , Masculino , Complicações Pós-Operatórias/epidemiologia , Período Pós-Operatório
10.
J Am Med Dir Assoc ; 16(8): 661-7, 2015 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-25864084

RESUMO

OBJECTIVES: Hip fractures (HFs) in old age frequently cause severe functional impairment and deteriorating autonomy in everyday life. Many older patients with HFs are malnourished or at risk of malnutrition. In this study, we examined the relationship between nutritional status of geriatric patients before HF and their functional and clinical course up to 6 months after hospital discharge. DESIGN: Observational study with follow-up after 6 months. SETTING: Four wards of the department of trauma and orthopedic surgery of a large urban maximum care hospital (Klinikum Nürnberg, Nuremberg, Germany). PARTICIPANTS: Geriatric patients aged ≥75 years with surgically repaired proximal femoral fracture. MEASUREMENTS: Prefracture nutritional status was determined by Mini Nutritional Assessment (MNA). Comorbidities and complications during hospital stay were obtained from medical documentation. Functional status before HF, postoperatively, at hospital discharge, and 6 months later was assessed by Barthel Index for activities of daily living (ADL) and patients' mobility level and related to MNA categories. Associations were evaluated using χ(2), Fisher exact, Kruskal-Wallis, Mann-Whitney-U, Jonckheere-Terpstra, and Cochrane-Armitage tests as appropriate, as well as analysis of covariance with repeated measures. RESULTS: Of 97 included patients, 17% were malnourished and 38% at risk of malnutrition before HF. Participants with (risk of) malnutrition were equally mobile but more dependent in ADL prior to HF than well-nourished patients (P < .001). Independent of nutritional status, after 6 months 68% of participants had not regained their prefracture level of independence in ADL. According to analysis of covariance, the ADL development over time until follow-up 6 months after hospital discharge did not depend on nutritional status. However, at follow-up malnourished patients more often suffered from remaining losses in ADL ≥25% of initial Barthel Index points (P = .033) and less often had regained their prefracture mobility level (P = .020) than well-nourished patients. Clinical course did not differ significantly between the groups with different nutritional status. CONCLUSIONS: In this study with geriatric HF patients from all functional and cognitive levels, worse prefracture nutritional status was associated with worse functional status and more frequent remaining functional loss, whereas the trajectory of ADL recovery and clinical course did not differ significantly. Further studies with sufficient statistical power are needed to substantiate these inconclusive results. In order to clarify the association of nutritional status with functional and clinical course in geriatric patients after HF, they should preferably focus on the role of nutritional management during the hospital stay.


Assuntos
Atividades Cotidianas , Avaliação Geriátrica , Fraturas do Quadril/fisiopatologia , Desnutrição/complicações , Avaliação Nutricional , Idoso , Comorbidade , Feminino , Alemanha , Fraturas do Quadril/cirurgia , Humanos , Masculino , Complicações Pós-Operatórias
11.
Z Gerontol Geriatr ; 48(1): 4-9, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25592177

RESUMO

The number of people with functional limitations, cognitive impairment and disability with unscheduled, unintended contact to emergency departments seeking acute medical care is increasing. With this, the problem of how to identify elderly people in need for acute geriatric care has evolved. The best solution to the problem would be to perform comprehensive geriatric assessment during the initial contact; however, comprehensive geriatric assessment is considered too complex and therefore not feasible for emergency departments. Instead, screening instruments have been developed and proposed. In this narrative review, selected screening instruments are discussed. The instrument best studied in various settings and countries is the Identification of Seniors At Risk (ISAR) screening tool which contains six simple questions that are easy to administer and can be assessed even in urgent situations. In recent years, several studies have examined the validity of ISAR in different European countries. Most of these studies, including one German study and a recent systematic review, confirmed the validity of ISAR. Unfortunately, evidence is conflicting, as some studies found only weak or even no association between ISAR and negative health outcomes. Other instruments have been investigated to a lesser extent and do not indicate obvious advantages over ISAR. Despite growing evidence in the field, there are still many uncertainties. Further research is needed to solve existing inconsistencies and to assess how elderly patients screened positive for acute geriatric care needs can best be managed further.


Assuntos
Serviço Hospitalar de Emergência/organização & administração , Serviços de Saúde para Idosos/organização & administração , Programas de Rastreamento/organização & administração , Avaliação das Necessidades/organização & administração , Medição de Risco/métodos , Inquéritos e Questionários , Idoso , Idoso de 80 Anos ou mais , Feminino , Avaliação Geriátrica , Alemanha , Humanos , Masculino , Programas de Rastreamento/métodos
12.
Gerontology ; 60(5): 413-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24969966

RESUMO

BACKGROUND: The identification of patients at high risk for adverse outcomes [death, unplanned readmission to emergency department (ED)/hospital, functional decline] plays an important role in emergency medicine. The Identification of Seniors at Risk (ISAR) instrument is one of the most commonly used and best-validated screening tools. As to the authors' knowledge so far there are no data on any screening tool for the identification of older patients at risk for a negative outcome in Germany. OBJECTIVES: To evaluate the validity of the ISAR screening tool in a German ED. DESIGN: This was a prospective single-center observational cohort study in an ED of an urban university-affiliated hospital. Participants were 520 patients aged ≥75 years consecutively admitted to the ED. MEASUREMENTS: The German version of the ISAR screening tool was administered directly after triage of the patients. Follow-up telephone interviews to assess outcome variables were conducted 28 and 180 days after the index visit in the ED. The primary end point was death from any cause or hospitalization or recurrent ED visit or change of residency into a long-term care facility on day 28 after the index ED visit. RESULTS: The mean age ± SD was 82.8 ± 5.0 years. According to ISAR, 425 patients (81.7%) scored ≥2 points, and 315 patients (60.5%) scored ≥3 points. The combined primary end point was observed in 250 of 520 patients (48.1%) on day 28 and in 260 patients (50.0%) on day 180. Using a continuous ISAR score the area under the curve on day 28 was 0.621 (95% confidence interval, CI 0.573-0.669) and 0.661 (95% CI 0.615-0.708) on day 180, respectively. CONCLUSION: The German version of the ISAR screening tool acceptably identified elderly patients in the ED with an increased risk of a negative outcome. Using the cutoff ≥3 points instead of ≥2 points yielded better overall results.


Assuntos
Serviço Hospitalar de Emergência , Avaliação Geriátrica/métodos , Medição de Risco/métodos , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Avaliação Geriátrica/estatística & dados numéricos , Alemanha , Humanos , Masculino , Programas de Rastreamento/métodos , Programas de Rastreamento/estatística & dados numéricos , Estudos Prospectivos , Medição de Risco/estatística & dados numéricos
13.
Arch Orthop Trauma Surg ; 133(11): 1527-31, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23995550

RESUMO

PURPOSE: To evaluate changes in hospital length-of-stay and time-to-operation of older hip fracture patients before and after the foundation of a co-managed Geriatric Fracture Center (GFC). METHODS: A co-managed GFC was established in a German level-1 trauma center. In a retrospective cohort study, we analyzed femoral neck fracture patients >60 years treated with hemiarthroplasty. Patients treated within the first year after foundation of the GFC were compared to the patients treated during the year before. One-way ANOVA was performed to identify differences regarding time-to-operation and hospital length-of-stay. RESULTS: One hundred and fourteen patients of the GFC were compared to 169 patients previously treated without co-management. Mean patient age did not significantly differ (81.9 vs. 81.5 years; p = 0.7), nor did gender distribution. Hospital length-of-stay was significantly shorter after foundation of the GFC (13.9 vs. 16.8 days; p = 0.007). The same is true for the interval between hospital admission and operation, which decreased from 3.1 to 2.1 days (p = 0.029). Early surgical complication rate was not significantly affected by GFC foundation (7.7 % pre-GFC vs. 9.6 % GFC; p = 0.6), nor was inpatient mortality (5.9 % pre-GFC vs. 4.4 % GFC; p = 0.6). Subgroup analysis revealed that GFC patients without early surgical complications displayed a reduced length-of-stay (LOS), whereas LOS was even prolonged in GFC patients with surgical complications. CONCLUSIONS: A co-managed GFC offering an organized fracture program for the elderly can reduce hospital length-of-stay and time-to-operation in hip fracture patients. A significant effect can be observed within the first year after establishment of a GFC.


Assuntos
Fraturas do Colo Femoral/cirurgia , Tempo de Internação/estatística & dados numéricos , Tempo para o Tratamento/estatística & dados numéricos , Centros de Traumatologia/organização & administração , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Geriatria , Humanos , Masculino , Estudos Retrospectivos
14.
Int Orthop ; 36(11): 2219-23, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22872411

RESUMO

PURPOSE: Hemiarthroplasty (HA) is an established treatment for femoral neck fractures of the elderly. Several surgical approaches are currently used including dorsal and transgluteal. It is still unclear whether one approach may be advantageous. We compared early complication rates after dorsal and transgluteal approaches. METHODS: We retrospectively analysed a cohort including 704 consecutive patients who received HA for femoral neck fracture; 212 male and 492 female patients were included, and the mean age was 80.4 years (SD 9.8 years). In 487 patients a dorsal and in 217 a transgluteal approach was chosen. In all patients an Excia stem with self-centring bipolar head manufactured by Aesculap (Tuttlingen, Germany) was used. We evaluated early postoperative complications including dislocation, infection, haematoma, seroma and perioperative fracture. Complication rates after dorsal and transgluteal approaches were calculated and compared by the chi-square test. RESULTS: After a dorsal approach 10.5 % [confidence interval (CI) 7.7-13.2 %] of the patients suffered one or more early complications. Following a transgluteal approach this proportion was 9.7 % (CI 5.7-13.6 %), which was not significantly different (p = 0.75). The predominant complication after a dorsal approach was dislocation (3.9 %; CI 2.2-5.6 %). The dislocation rate after a transgluteal approach was significantly lower (0.5 %; CI 0-1.4 %). Postoperative haematoma however was seen after a transgluteal approach in 5.5 % (CI 2.5-8.6 %), which was significantly more frequent than after a dorsal approach (1.2 %; CI 0.2-2.2 %). The frequency of the other types of complications did not significantly differ. CONCLUSIONS: The rate of early surgical complications after dorsal and transgluteal approaches is not significantly different. However, the dorsal approach predisposed to dislocation, whereas the transgluteal approach predisposed to haematoma.


Assuntos
Artroplastia de Quadril/métodos , Fraturas do Colo Femoral/cirurgia , Hemiartroplastia/métodos , Articulação do Quadril/cirurgia , Complicações Pós-Operatórias , Adulto , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/efeitos adversos , Mau Alinhamento Ósseo/epidemiologia , Mau Alinhamento Ósseo/etiologia , Cimentação , Feminino , Fraturas do Colo Femoral/fisiopatologia , Alemanha/epidemiologia , Hematoma/epidemiologia , Hematoma/etiologia , Hemiartroplastia/efeitos adversos , Articulação do Quadril/fisiopatologia , Prótese de Quadril , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Resultado do Tratamento
15.
Ther Umsch ; 67(2): 63-7, 2010 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-20131213

RESUMO

Although a lot is known regarding the epidemiology and aetiology of this condition, the pathophysiology of delirium remains poorly understood. Today, the leading hypothesized mechanism for the pathogenesis of delirium focuses on a central cholinergic deficiency and dopamine excess. Besides, other neurotransmitters, such as dopamine, serotonin, norepinephrine, glutamate and gamma-aminobutyric acid (GABA) may also contribute to delirium. Moreover, cytokines including interleukin-1, interleukin-2, interleukin-6, interferon and tumour necrosis factor alpha (TNF-alpha) can lead to an imbalance among the different neurotransmitters and thereby lead to an activation of the hypothalamic-pituitary-adrenocortical axis (HPA axis). The article reviews the current pathophysiological findings that may underly delirious states.


Assuntos
Encéfalo/fisiopatologia , Delírio/fisiopatologia , Acetilcolina/fisiologia , Idoso , Encéfalo/efeitos dos fármacos , Antagonistas Colinérgicos/efeitos adversos , Antagonistas Colinérgicos/uso terapêutico , Citocinas/fisiologia , Delírio/induzido quimicamente , Humanos , Sistema Hipotálamo-Hipofisário/efeitos dos fármacos , Sistema Hipotálamo-Hipofisário/fisiopatologia , Neurotransmissores/fisiologia , Sistema Hipófise-Suprarrenal/efeitos dos fármacos , Sistema Hipófise-Suprarrenal/fisiopatologia , Receptores Colinérgicos/efeitos dos fármacos , Receptores Colinérgicos/fisiologia
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