Diffusion-Weighted Imaging Changes in a Child With Posterior Ischemic Optic Neuropathy.

BACKGROUND: Posterior ischemic optic neuropathy results from ischemia of the retrobulbar aspect of the optic nerve. It presents as acute loss of vision without optic disc swelling. This is rare in children, with only seven cases reported to date. Neuroimaging is frequently used to aid in the diagnosis of acute visual complaints in children; however, none of the cases described to date delineate the neuroimaging findings of this entity in children. METHODS: We retrospectively reviewed the electronic medical record. RESULTS: We describe the MRI findings in a 10-month-old boy with posterior ischemic optic neuropathy after intraophthalmic artery injection of chemotherapy for retinoblastoma. CONCLUSIONS: As targeted therapies for retinoblastoma and other diseases amenable to intravascular treatment delivery are more frequently used, the risk of grave vision-related side effects increases. Posterior ischemic optic neuropathy should be considered in the differential diagnosis of any child presenting with acute loss of vision. Dedicated imaging of the orbits can elucidate specific findings that may aid in the diagnosis of this entity in children.

An assessment of the cost-effectiveness, safety of referral and patient satisfaction of a general practice teledermatology service.

BACKGROUND: In the cost-constrained NHS and in the quest for rapid diagnosis, teledermatology is a tool that can be used within general practice to aid in the diagnosis of benign-looking skin lesions and reduce referrals to secondary care. The setting for the study was a single general practice of 6500 patients in suburban Greater London. The aim of the study was to determine: (1) whether teledermatology in a single general practice is cost-effective, (2) whether the correct types of cases are being referred, and (3) if patients are satisfied with the service. METHODS: Teledermatology was provided by a private provider. A trained member of staff took photographs in the practice. A consultant dermatologist carried out reporting. This is a retrospective analysis of case records over three years. The cases were adult patients (aged 18+) using teledermatology for the diagnosis and management of skin lesions thought to be benign by the general practitioner. Cost-effectiveness was calculated by considering savings made through reduced referral to secondary care, taking into account the cost of the service. To evaluate whether the correct cases were referred we reviewed whether the assessing dermatologist identified any previously undiagnosed skin cancer. Patient satisfaction assessment was performed using a standard questionnaire. RESULTS: Two hundred and forty-eight patients had teledermatology. These were patients who would have been referred to secondary care for a routine appointment. Of these, 102 were subsequently referred to secondary care and 146 were managed within the practice. Teledermatology saved £12 460 over the 3-year period. Patients were followed for up to 51 months and no lesions were found to be malignant. Ninety-seven percent of patients rated themselves as satisfied/very satisfied and 93% found the procedure comfortable/very comfortable. The median wait for the photos to be taken was 7 days, and 1-2 weeks for results. CONCLUSIONS: Teledermatology has been shown to be cost-effective, with referrals identified correctly when employed in this general practice setting. Satisfaction with the service was high.