RESUMO
BACKGROUND: Periprosthetic joint infection following hip and knee arthroplasty leads to poor outcomes and exorbitant costs. Topical vancomycin powder has been shown to decrease infection in many procedures such as spine surgery. The role of vancomycin powder in the setting of total joint arthroplasty remains undefined. Our aim was to evaluate the efficacy of intra-articular vancomycin powder in preventing infection in a rat model of a contaminated intra-articular implant. METHODS: Thirty-two female Sprague-Dawley rats underwent knee arthrotomy and implantation of a femoral intramedullary wire with 1 mm of intra-articular communication. The knee joint was also inoculated with 1.5 × 10 colony forming units (CFU)/mL of methicillin-resistant Staphylococcus aureus (MRSA). Four treatment groups were studied: (1) no antibiotics (control), (2) preoperative systemic vancomycin, (3) intra-articular vancomycin powder, and (4) both systemic vancomycin and intra-articular vancomycin powder. The animals were killed on postoperative day 6, and distal femoral bone, joint capsule, and the implanted wire were harvested for bacteriologic analysis. Statistical analyses were performed using Wilcoxon rank sum and Fisher exact tests. RESULTS: There were no postoperative deaths, wound complications, signs of vancomycin-related toxicity, or signs of systemic illness in any of the treatment groups. There were significantly fewer positive cultures in the group that received vancomycin powder in combination with systemic vancomycin compared with the group that received systemic vancomycin alone (bone: 0% versus 75% of 8, p = 0.007; Kirschner wire: 0% versus 63% of 8, p = 0.026; whole animal: 0% versus 88% of 8, p = 0.01). Only animals that received both vancomycin powder and systemic vancomycin showed evidence of complete elimination of bacterial contamination. CONCLUSIONS: In a rat model of a contaminated intra-articular implant, use of intra-articular vancomycin powder in combination with systemic vancomycin completely eliminated MRSA bacterial contamination. Animals treated with systemic vancomycin alone had persistent MRSA contamination. CLINICAL RELEVANCE: This animal study presents data suggesting that the use of intra-articular vancomycin powder for reducing the risk of periprosthetic joint infections should be investigated further in clinical studies.
Assuntos
Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Infecções Relacionadas à Prótese/tratamento farmacológico , Infecções Relacionadas à Prótese/microbiologia , Infecções Estafilocócicas/tratamento farmacológico , Vancomicina/farmacologia , Animais , Modelos Animais de Doenças , Feminino , Pós , Ratos , Ratos Sprague-DawleyRESUMO
Polyethylene wear and subsequent osteolysis are major obstacles to the long-term success of total hip arthroplasty (THA). We conducted a study to determine the incidence of loose acetabular components that did not show frank signs of loosening on either plain radiography or computed tomography (CT), or radiographically silent loosening (RSL). In this retrospective study, we evaluated patients who underwent revision THA and were evaluated with plain radiography and CT between 2000 and 2012. Any patient with imaging that showed signs of component movement was excluded. Of the 104 patients who met the study inclusion criteria, 17 (16.3%) met the criteria for RSL of the acetabular shell. Patients with RSL presented at a similar age (P = .961) and with a similar sex profile (P = .185) compared with patients with stable acetabular components and were more likely to present with pain (P = .0487). Acetabular components may be loose even if there is no evidence of component migration on radiographic studies. Surgeons should be aware of the incidence of RSL and the potential of RSL to affect patient care and potential surgical options.
Assuntos
Acetábulo/diagnóstico por imagem , Artroplastia de Quadril , Articulação do Quadril/diagnóstico por imagem , Prótese de Quadril , Falha de Prótese , Acetábulo/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Feminino , Articulação do Quadril/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Desenho de Prótese , Radiografia , Reoperação , Estudos RetrospectivosRESUMO
PSI software adjusts preoperative planning to accommodate differences in implant design. Such adjustments may influence the accuracy of intraoperative jig placement, bone resection, or component placement. Our purpose was to determine whether implant design influences PSI accuracy. 96 and 123 PSI TKA were performed by a single surgeon using two different implant systems and identical PSI software. Femoral coronal alignment outliers were greater for Implant 1 (23.9% Implant 1 vs. 13.4% Implant 2; P=0.050). Tibial coronal alignment outliers were greater for Implant 2 (10.9% Implant 1 vs. 22.7% Implant 2; P=0.025). There was no difference in overall mechanical axes. Differences in implant design can influence bone resection and component alignment. PSI software rationale must align with surgeons' intraoperative goals.
Assuntos
Artroplastia do Joelho/instrumentação , Prótese do Joelho , Desenho de Prótese , Idoso , Artroplastia do Joelho/métodos , Feminino , Fêmur/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Software , Cirurgia Assistida por Computador , Tíbia/cirurgiaRESUMO
If PSI preoperative planning were perfectly precise, a single MRI would give rise to one preoperative plan. Our purpose was to determine whether a single MRI inputted into two different PSI software yielded differences in preoperative alignment determination, component sizing, and bone resection within the preoperative plan. This prospective comparative study evaluated 40 preoperative plans generated by two PSI software given identical MRI. Femoral and tibial component sizes differed between software in 37.5% and 30.0% of cases, respectively. The maximum difference in bone resection between software ranged from 2.2mm to 5.1mm. Surgeons should be prepared to intraoperatively deviate from PSI selected size by 1 size. It may be necessary to fine tune soft tissue balancing when using a PSI system.
Assuntos
Artroplastia do Joelho/métodos , Prótese do Joelho , Imageamento por Ressonância Magnética , Cirurgia Assistida por Computador/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Simulação por Computador , Feminino , Fêmur/cirurgia , Humanos , Processamento de Imagem Assistida por Computador , Masculino , Pessoa de Meia-Idade , Período Pré-Operatório , Estudos Prospectivos , Reprodutibilidade dos Testes , Software , Tíbia/cirurgia , Resultado do TratamentoRESUMO
INTRODUCTION: Some patients undergoing total joint arthroplasty are at increased risk for venous thromboembolism (VTE). The aim of the present study was to evaluate the safety and efficacy of prIVCF in preventing PE in patients undergoing joint replacement surgery who are at high-risk for VTE. MATERIALS AND METHODS: In this prospective, IRB-approved study, prIVCF were placed in consecutive patients who met specific high-risk criteria (history of VTE or hypercoaguable state) prior to total joint arthroplasty. Patients were followed until the IVC filter was removed. Outcomes and complications were recorded per Society of Interventional Radiology guidelines. RESULTS: One hundred and nine potentially retrievable IVC filters were placed in 105 patients, who all subsequently underwent joint arthroplasty. One hundred eight IVC filters (98.9%) were retrieved successfully in a mean time of 44.1 days (range 13-183 days). There was 1 failed IVC filter retrieval attempt (0.9%) at 46 days post implantation. Two patients (1.9%) presented with recurrent PE and were successfully treated with anticoagulation prior to IVC filter retrieval. There were no fatalities from perioperative PE. In 1 patient (0.9%), a fractured filter leg had embolized during retrieval. CONCLUSION: Potentially retrievable IVC filters are safe and effective for prophylaxis against PE in patients at high-risk for VTE undergoing joint arthroplasty.
RESUMO
PURPOSE: The purpose of this study was to evaluate clinical, functional, and radiographic outcomes following total knee arthroplasty (TKA) performed with patient-specific instrumentation (PSI), computer-assisted surgery (CAS), and manual instruments at short-term follow-up. METHODS: 122 TKAs were performed by a single surgeon: 42 with PSI, 38 with CAS, and 40 with manual instrumentation. Preoperative, 1-month, and 6-month clinical and functional outcomes were measured using the Knee Society scoring system (knee score, function score, range of motion, and pain score). Improvements in clinical and functional outcomes from the preoperative to postoperative period were analyzed. Preoperative and postoperative radiographs were measured to evaluate limb and component alignment. RESULTS: Preoperative, 1-month postoperative, and 6-month postoperative knee scores, function scores, range of motion, and pain scores were highest in the PSI group compared to CAS and manual instrumentation. At 6-month follow-up, PSI TKA was associated with a statistically significant improvement in functional score when compared to manual TKA. Otherwise, there were no statistically significant differences in improvements among PSI, CAS, and manual TKA groups. CONCLUSION: The higher preoperative scores in the PSI group limits the ability to draw definitive conclusions from the raw postoperative scores, but analyzing the changes in scores revealed that PSI was associated with a statistically significant improvement in Knee Society Functional score at 6-month post-TKA as compared to CAS or manual TKA. This may be attributable to improvements in component rotation and positioning, improved component size accuracy, or other factors that are not discernible on plain radiograph.
Assuntos
Artroplastia do Joelho/instrumentação , Articulação do Joelho/diagnóstico por imagem , Cirurgia Assistida por Computador/instrumentação , Tomografia Computadorizada por Raios X , Idoso , Idoso de 80 Anos ou mais , Desenho de Equipamento , Feminino , Seguimentos , Humanos , Articulação do Joelho/fisiopatologia , Articulação do Joelho/cirurgia , Masculino , Pessoa de Meia-Idade , Posicionamento do Paciente , Amplitude de Movimento Articular , Fatores de Tempo , Resultado do TratamentoRESUMO
Uncemented femoral implants of various designs have proved to provide stable initial and long-term fixation in patients who undergo total hip arthroplasty. Challenges in primary total hip arthroplasty have led to the evolution of short stem designs. These challenges include proximal/metaphyseal and distal/diaphyseal mismatch; facilitation of less-invasive surgical exposures, especially the direct anterior approach; and bone preservation for potential revision surgery.
Assuntos
Artroplastia de Quadril , Colo do Fêmur/cirurgia , Instabilidade Articular , Osteotomia/métodos , Complicações Pós-Operatórias , Artroplastia de Quadril/efeitos adversos , Artroplastia de Quadril/métodos , Fenômenos Biomecânicos , Epífises/fisiopatologia , Epífises/cirurgia , Colo do Fêmur/fisiopatologia , Humanos , Instabilidade Articular/etiologia , Instabilidade Articular/fisiopatologia , Instabilidade Articular/prevenção & controle , Dispositivos de Fixação Ortopédica/normas , Avaliação de Resultados em Cuidados de Saúde , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/prevenção & controle , Desenho de Prótese , Recuperação de Função Fisiológica , Reoperação/métodos , Reoperação/estatística & dados numéricosRESUMO
Readmission has been cited as an important quality measure in the Patient Protection and Affordable Care Act. We queried an electronic database for all patients who underwent Total Hip Arthroplasty or Total Knee Arthroplasty at our institution from 2006 to 2010 and identified those readmitted within 90 days of surgery, reviewed their demographic and clinical data, and performed a multivariable logistic regression analysis to determine significant risk factors. The overall 90-day readmission rate was 7.8%. The most common readmission diagnoses were related to infection and procedure-related complications. An increased likelihood of readmission was found with coronary artery disease, diabetes, increased LOS, underweight status, obese status, age (over 80 or under 50), and Medicare. Procedure-related complications and wound complications accounted for more readmissions than any single medical complication.
Assuntos
Artroplastia de Quadril/estatística & dados numéricos , Artroplastia do Joelho/estatística & dados numéricos , Artropatias/cirurgia , Readmissão do Paciente/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Humanos , Pessoa de Meia-Idade , Fatores de RiscoRESUMO
Readmission rates have been cited as an important quality measure in the Affordable Care Act. Accordingly, understanding and accurately tracking the causes for readmission will be increasingly important. We queried an electronic database for all patients who underwent primary THA or TKA at our institution from 2006 through 2010. We identified those readmitted within 90 days of surgery and analyzed 87 random de-identified medical records. We then assigned a clinical diagnosis for each readmission, which was then compared with the coder-derived diagnosis by ICD-9 code. The overall 90-day readmission rate was 7.9%. We identified 22 of 87 patients for whom there was disagreement (25.3%, 95% CI=16.6-35.8%). The most common were procedure-related complications. Coded diagnoses frequently did not correlate with the physician-derived diagnoses. The unverified use of coded readmission diagnoses in calculating quality measures may not be clinically relevant.
Assuntos
Artroplastia de Substituição , Readmissão do Paciente/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Indicadores de Qualidade em Assistência à Saúde , Feminino , Humanos , Illinois/epidemiologia , Masculino , Patient Protection and Affordable Care Act , Fatores de Risco , Fatores de Tempo , Estados Unidos/epidemiologiaRESUMO
The purpose of this study was to determine whether differences in clinical, functional, or radiographic outcomes existed at 5-year follow-up between patients who underwent computer-assisted or manual total knee arthroplasty (TKA). Seventy-eight consecutive TKAs were performed by a single surgeon who had extensive experience performing computer-assisted and manual TKA. The manual group (n=40) and computer-assisted group (n=38) were similar with regard to age, sex, diagnosis, body mass index, surgical technique, implants, perioperative management, Knee Society scores, and anteroposterior mechanical axis. Sixty-three (manual group, n=34; computer-assisted group, n=29) patients were available for final follow-up. At 5-year follow-up, no statistically significant differences were found in Knee Society knee score (P=.289), function score (P=.272), range of motion (P=.284), pain score (P=.432), or UCLA activity score (P=.109) between the 2 groups. Postoperative radiographs showed a significant difference in the mechanical axis (P=.004) between the 2 groups; however, both groups achieved a neutral mechanical axis of ±3° (computer-assisted group mean, 2.0°; manual group mean, -0.24°).When TKA was performed by an experienced surgeon, no significant difference was identified at 5-year follow-up between patients who underwent computer-assisted vs manual TKA.
Assuntos
Artroplastia do Joelho/estatística & dados numéricos , Instabilidade Articular/epidemiologia , Instabilidade Articular/cirurgia , Cirurgia Assistida por Computador/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Illinois/epidemiologia , Instabilidade Articular/diagnóstico , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Prevalência , Recuperação de Função Fisiológica , Medição de Risco , Resultado do TratamentoRESUMO
INTRODUCTION: Patient-specific guides (PSG) and computer-assisted navigation (CAN) are technologies that have been developed to improve the accuracy and reproducibility of total knee arthroplasty (TKA). The purpose of this study is to compare the methodology by which a PSG system and an intraoperative navigation system (CAN) perform an anatomical registration and correctly predict femoral component size in TKA. METHODS: One hundred and eleven PSG TKA were performed, 30 of which were concurrently evaluated with CAN. PSG-predicted and CAN-predicted femoral component size were compared with the actual component selection. The process by which PSG and CAN determines component sizing was evaluated. RESULTS: The PSG system was both more accurate and more precise than the CAN navigation system in predicting femoral component size in TKA. CONCLUSION: In this study, the surgeon's final component selection was more likely to be in accordance with the PSG rather than the CAN sizing algorithm. This study suggests that intraoperative surface registration may not be as accurate as preoperative three-dimensional magnetic resonance imaging reconstructions for establishing optimal femoral component sizing.
Assuntos
Artroplastia do Joelho/estatística & dados numéricos , Instabilidade Articular/epidemiologia , Instabilidade Articular/cirurgia , Articulação do Joelho/cirurgia , Ajuste de Prótese/estatística & dados numéricos , Cirurgia Assistida por Computador/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Joelho/métodos , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Ajuste de Prótese/métodos , Medição de Risco , Cirurgia Assistida por Computador/métodos , Resultado do TratamentoRESUMO
BACKGROUND: Limitations of conventional uncemented femoral stems persist, including proximal-distal mismatch, nonideal load transfer, loss of bone, and difficulties with minimally invasive surgery. Metaphyseal-engaging short-stem implants have been designed to address these issues in THA. While these devices have been studied in younger patients, it is unclear whether they offer advantages in older patients. QUESTIONS/PURPOSES: We asked whether the stability and bony ingrowth of an off-the-shelf short stem in patients 70 years and older were similar to those achieved in patients younger than 70 years at 2-year followup. Furthermore, we asked whether pain and function scores were affected by age, bone quality, or varus alignment. PATIENTS AND METHODS: We retrospectively reviewed 60 patients (65 hips) 70 years and older (mean, 75 years; range, 70-86 years) treated with an uncemented short stem (range, 90-105 mm). We compared radiographic alignment, stability, and bony ingrowth, as well as Harris hip scores and WOMAC pain scores, to a cohort of 89 patients (91 hips) younger than 70 years. Minimum followup was 24 months (mean, 35 months; range, 24-60 months). RESULTS: Radiographs showed proximal bony ingrowth and stable fixation of all implants. Average Harris hip score at last followup was 88 (range, 70-100) for the 70 years and older cohort and 93 (range, 70-100) for younger than 70 years cohort; no patients reported thigh pain. Postoperative WOMAC scores averaged 6 (range, 0-43) and 5 (range, 0-25), respectively. CONCLUSIONS: Short-stem implants provide solid, dependable fixation in osteoporotic bone at minimum 2-year followup, while meeting some of the limitations in conventional primary THA. LEVEL OF EVIDENCE: Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Assuntos
Artroplastia de Quadril/instrumentação , Fêmur/cirurgia , Articulação do Quadril/cirurgia , Prótese de Quadril , Osteoporose/cirurgia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Artralgia/etiologia , Artroplastia de Quadril/efeitos adversos , Distribuição de Qui-Quadrado , Chicago , Feminino , Fêmur/diagnóstico por imagem , Articulação do Quadril/diagnóstico por imagem , Articulação do Quadril/fisiopatologia , Humanos , Instabilidade Articular/etiologia , Instabilidade Articular/prevenção & controle , Masculino , Pessoa de Meia-Idade , Osseointegração , Osteoporose/complicações , Osteoporose/diagnóstico por imagem , Osteoporose/fisiopatologia , Medição da Dor , Dor Pós-Operatória/etiologia , Desenho de Prótese , Radiografia , Amplitude de Movimento Articular , Recuperação de Função Fisiológica , Estudos Retrospectivos , Fatores de Tempo , Resultado do TratamentoRESUMO
A dual-mobility acetabular component consists of a large, fixed, porous-coated acetabular component and a bipolar femoral component. These components are often called tripolar components. This configuration provides a stable, well-fixed implant platform against bone and 2 articular interfaces, a large polyethylene surface directly apposed to a highly polished metal implant, and a standard-sized (28- or 32-mm) femoral head captured within polyethylene. The dual-mobility cup appears to offer a safe, effective, durable solution to hip instability. The concept has extensive laboratory and clinical support. Although the long-term durability of these implants is unknown, the tested wear rates of a dual-mobility design with the current generation of highly cross-linked polyethylene are significantly lower than any previously reported wear rates. The recently introduced modular dual-mobility shell offers surgeons substantial flexibility in addressing the issue of hip instability with a cost-efficient, familiar option.
Assuntos
Artroplastia de Quadril/instrumentação , Luxação do Quadril/prevenção & controle , Prótese de Quadril , Instabilidade Articular/prevenção & controle , Artroplastia de Quadril/métodos , Materiais Revestidos Biocompatíveis , Luxação do Quadril/diagnóstico por imagem , Instabilidade Articular/diagnóstico por imagem , Desenho de Prótese , Falha de Prótese , Radiografia , Fatores de TempoRESUMO
A dual-mobility acetabular component consists of a large, fixed, porous-coated acetabular component and a bipolar femoral component. These components are often called tripolar components. This configuration provides a stable, well-fixed implant platform against bone and 2 articular interfaces, a large polyethylene surface directly apposed to the highly polished metal shell, and a standard sized (28 mm, 32 mm) femoral head captured within polyethylene. The dual-mobility cup was designed to reduce the incidence of dislocations in patients at increased risk of instability (eg, patients undergoing revision). The cup appears to offer a safe, effective, durable solution to hip instability. The concept has extensive laboratory and clinical support. Although the long-term durability of dual-mobility cups, particularly in young, active, large patients, is not known, the tested wear rates of the dual-mobility design with the current generation of highly cross-linked polyethylene are significantly lower than any previously reported wear rates. The recently released anatomic dual-mobility cup seeks to reduce the potential for iliopsoas impingement while retaining the stability and wear characteristics of the original dual-mobility design.
Assuntos
Artroplastia de Quadril/instrumentação , Articulação do Quadril/cirurgia , Prótese de Quadril , Instabilidade Articular/cirurgia , Doença Crônica , Luxação do Quadril/prevenção & controle , Humanos , Polietileno , Desenho de PróteseRESUMO
UNLABELLED: Precise pre- and postoperative anatomic measurements are necessary to plan, perform, and evaluate total knee arthroplasty (TKA). We evaluated the relationship between radiographic and navigation alignment measurements, identified sources of error in radiographic and navigated alignment assessment, and determined the differences between desired and clinically accepted alignment. Fifty-eight computer-assisted TKAs were performed and limb alignment measurements were recorded both pre- and postoperatively with standard radiographs and with an intraoperative navigation system. Intraoperative navigation produced consistent navigation-generated alignment results that were within 1 degrees of the desired alignment. The difference between preoperative radiographic and navigation measurements varied by as much as 12 degrees and the difference between postoperative radiographic and navigation measurements varied by as much as 8 degrees. This discrepancy depended on the degree of limb deformity. Postoperative radiographic measurements have inherent limitations. Navigation can generate precise, accurate, and reproducible alignment measurements. This technology can function as an effective tool for assessing pre- and postoperative limb alignment and relating intraoperative alignment measurements to clinical and functional outcomes. LEVEL OF EVIDENCE: Level II, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
Assuntos
Artrografia/métodos , Artroplastia do Joelho/métodos , Articulação do Joelho/diagnóstico por imagem , Monitorização Intraoperatória/métodos , Osteoartrite do Joelho/cirurgia , Cirurgia Assistida por Computador/métodos , Seguimentos , Humanos , Articulação do Joelho/cirurgia , Variações Dependentes do Observador , Osteoartrite do Joelho/diagnóstico por imagem , Reprodutibilidade dos Testes , Fatores de Tempo , Resultado do TratamentoRESUMO
The purpose of this study was to examine the clinical outcomes associated with the Columbus primary total knee replacement (B. Braun Aesculap, Tuttlingen, Germany), correlate these outcomes with variables measured intraoperatively with the OrthoPilot navigation system (B. Braun Aesculap), and explore the full potential of automating the process of intraoperative data collection. Clinical and functional outcomes at 2.5 years were similar to results reported in previous studies. Correlations were seen between initial mechanical axis deformity and postoperative range of motion as well as between final mechanical axis alignment and the presence of flexion contractures at later followup. It is now possible to potentially stratify particular segments of patients and develop specific intraoperative alignment targets that are most likely to yield positive clinical and functional outcomes.
Assuntos
Artroplastia do Joelho/instrumentação , Artroplastia do Joelho/métodos , Prótese do Joelho , Recuperação de Função Fisiológica , Cirurgia Assistida por Computador/métodos , Idoso , Idoso de 80 Anos ou mais , Análise de Falha de Equipamento , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Pós-Operatórios/métodos , Prognóstico , Desenho de Prótese , Resultado do TratamentoRESUMO
UNLABELLED: We previously reported preoperative depression, anxiety, and pain were associated with greater pain, more utilization of healthcare resources, and worse outcome 1 year after total knee arthroplasty. We asked whether these outcomes persisted over time and whether patients with unexplained heightened pain early after surgery were ultimately satisfied. We prospectively followed and evaluated 83 patients (109 TKAs) 5 years postoperative. The mean age was 66 years; 55% were women. Preoperative pain and depression predicted lower Knee Society score mostly related to lower function subscores. Although anxiety was associated with greater pain, worse function, and more use of resources in the first year after surgery, anxiety did not affect ultimate outcome. Most patients required a full year to recover from surgery but with negligible improvements in most parameters afterward. However, patients with heightened, unexplained pain at 1 year had progressive improvement in pain over several years. By 5 years, nearly all of these patients were satisfied. Therefore, assuming good range of motion and well-aligned implants, most patients with pain 1 year after surgery can be reassured pain ultimately improves. Depression drives long-term outcomes; the Knee Society score is influenced by psychologic variables and does not solely reflect issues related to the knee. Expansion of this tool to include measures sensitive to psychologic and other health factors should be considered. LEVEL OF EVIDENCE: Level I, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.