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Ann Behav Med ; 52(2): 130-145, 2018 02 05.
Artigo em Inglês | MEDLINE | ID: mdl-29538627

RESUMO

Background: Close relationships play an integral role in human development, and robust evidence links marital separation and divorce to poor health outcomes. Social integration may play a key role in this association. In many ways, the study of marital separation and divorce provides an ideal model system for a more complete understanding of the association between life stress and physical health. Purpose: The current study investigated associations among objectively measured social integration, psychological distress, and biomarkers of immune health in recently separated adults (N = 49). Methods: We collected four measures of immune functioning-interleukin-6, C-reactive protein, and antibody titers to latent cytomegalovirus and Epstein-Barr virus-that were combined to yield a viral-Immune Risk Profile. To assess how variability in social integration is associated with immunological correlates following the end of a marriage, we incorporated observational ecological momentary assessment data using a novel methodology (the Electronically Activated Recorder). Results: We found that objectively measured social behaviors are associated with concurrent viral-Immune Risk Profile scores over and above the effects of psychological distress and that psychological distress may be linked to biomarkers of immune health through social integration. Conclusions: This research expands current knowledge of biomarkers of immune health after divorce and separation and includes a new methodology for objective measures of social engagement.


Assuntos
Anticorpos Antivirais/sangue , Proteína C-Reativa , Divórcio , Nível de Saúde , Interleucina-6/sangue , Comportamento Social , Apoio Social , Estresse Psicológico/imunologia , Adulto , Biomarcadores/sangue , Citomegalovirus/imunologia , Avaliação Momentânea Ecológica , Feminino , Herpesvirus Humano 4/imunologia , Humanos , Masculino , Pessoa de Meia-Idade , Fenótipo , Risco
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