RESUMO
Aspergoterpenins Aâ»D (1â»4), four new bisabolane sesquiterpenoid derivatives, were obtained from the endophytic fungus, Aspergillus versicolor, together with eight known compounds (5â»12), and their structures were elucidated by a comprehensive analysis of their NMR (Nuclear Magnetic Resonance), MS (Mass Spectrum) and CD (Circular Dichroism) spectra. Aspergoterpenin A (1) was the first example with a characteristic ketal bridged-ring part in the degraded natural bisabolane-type sesquiterpene structures. The compounds 1â»12 displayed no significant activities against four cancer cell lines (A549, Caski, HepG2 and MCF-7). Further, the antimicrobial activities to Erwinia carotovora sub sp. Carotovora were evaluated, and the results showed that compounds 1â»12 displayed antimicrobial activities with MIC values ranging from 15.2 to 85.2 µg/mL.
Assuntos
Anti-Infecciosos/farmacologia , Aspergillus/química , Pectobacterium carotovorum/efeitos dos fármacos , Sesquiterpenos/farmacologia , Células A549 , Anti-Infecciosos/química , Linhagem Celular Tumoral , Células Hep G2 , Humanos , Células MCF-7 , Testes de Sensibilidade Microbiana , Estrutura Molecular , Sesquiterpenos/químicaRESUMO
This paper presents an approach to optimize the electrical performance of dense-array concentrator photovoltaic system comprised of non-imaging dish concentrator by considering the circumsolar radiation and slope error effects. Based on the simulated flux distribution, a systematic methodology to optimize the layout configuration of solar cells interconnection circuit in dense array concentrator photovoltaic module has been proposed by minimizing the current mismatch caused by non-uniformity of concentrated sunlight. An optimized layout of interconnection solar cells circuit with minimum electrical power loss of 6.5% can be achieved by minimizing the effects of both circumsolar radiation and slope error.