Blood-based graphene oxide nanofluid flow through capillary in the presence of electromagnetic fields: A Sutterby fluid model.

Pumping devices with the electrokinetics phenomena are important in many microscale transport phenomena in physiology. This study presents a theoretical and numerical investigation on the peristaltic pumping of non-Newtonian Sutterby nanofluid through capillary in presence of electromagnetohydrodynamics. Here blood (Sutterby fluid) is taken as a base fluid and nanofluid is prepared by the suspension of graphene oxide nanoparticles in blood. Graphene oxide is extremely useful in the medical domain for drug delivery and cancer treatment. The modified Buongiorno model for nanofluids and Poisson-Boltzmann ionic distribution is adopted for the formulation of the present problem. Constitutive flow equations are linearized by the implementation of approximations of low Reynolds number, large wavelength, and the Debye-Hückel linearization. The numerical solution of reduced coupled and nonlinear set of equations is computed through Mathematica and graphical illustration is presented. Further, the impacts of buoyancy forces, thermal radiation, and mixed convection are also studied. It is revealed in this investigation that the inclusion of a large number of nanoparticles alters the flow characteristics significantly and boosts the heat transfer mechanism. Moreover, the pumping power of the peristaltic pump can be enhanced by the reduction in the width of the electric double layer which can be done by altering the electrolyte concentration.

Mathematical modeling and simulation of electromagnetohydrodynamic bio-nanomaterial flow through physiological vessels.

Gold-based metal nanoparticles serve a key role in diagnosing and treating important illnesses such as cancer and infectious diseases. In consideration of this, the current work develops a mathematical model for viscoelastic nanofluid flow in the peristaltic microchannel. Nanofluid is considered as blood-based fluid suspended with gold nanoparticles. In the investigated geometry, various parametric effects such as Joule heating, magnetohydrodynamics, electroosmosis, and thermal radiation have been imposed. The governing equations of the model are analytically solved by using the lubrication theory where the wavelength of the channel is considered large and viscous force is considered more dominant as compared to the inertia force relating the applications in biological transport phenomena. The graphical findings for relevant parameters of interest are given. In the current analysis, the ranges of the parameters have been considered as: 0<κ<6,0<λ1<0.6,2

Blood-based graphene oxide nanofluid flow through capillary in the presence of electromagnetic fields: A Sutterby fluid model.

Pumping devices with the electrokinetics phenomena are important in many microscale transport phenomena in physiology. This study presents a theoretical and numerical investigation on the peristaltic pumping of non-Newtonian Sutterby nanofluid through capillary in presence of electromagnetohydrodynamics. Here blood (Sutterby fluid) is taken as a base fluid and nanofluid is prepared by the suspension of graphene oxide nanoparticle in blood. Graphene oxide is extremely useful in the medical domain for drug delivery and cancer treatment. The modified Buongiorno model for nanofluids and Poisson-Boltzmann ionic distribution is adopted for the formulation of the present problem. Constitutive flow equations are linearized by the implementation of approximations low Reynolds number, large wavelength, and the Debye-Hückel linearization. The numerical solution of reduced coupled and nonlinear set of equations is computed through Mathematica and graphical illustration is presented. Further, the impacts of buoyancy forces, thermal radiation, and mixed convection are also studied. It is revealed in this investigation that the inclusion of a large number of nanoparticles alters the flow characteristics significantly and boosts the heat transfer mechanism. Moreover, the pumping power of the peristaltic pump can be enhanced by the reduction in the width of the electric double layer which can be done by altering the electrolyte concentration.

Signalling molecule transport analysis in lacunar-canalicular system.

Mechanical loading-induced fluid flow in lacunar-canalicular space (LCS) of bone excites osteocyte cells to release signalling molecules which initiate osteo-activities. Theoretical models considered canaliculi as a uniform and symmetrical space/channel in bone. However, experimental studies reported that canalicular walls are irregular and curvy resulting in inhomogeneous fluid motion which may influence the molecular transport. Therefore, a new mathematical model of LCS with curvy canalicular walls is developed to characterize cantilever bending-induced canalicular flow behaviour in terms of pore-pressure, fluid velocity, and streamlines. The model also analyses the mobility of signalling molecules involved in bone mechanotransduction as a function of loading frequency and permeability of LCS. Inhomogeneous flow is observed at higher loading frequency which amplifies mechanotransduction; nevertheless, it also promotes trapping of signalling molecules. The effects of shape and size of signalling molecules on transport behaviour are also studied. Trivially, signalling molecules larger in size and weight move slower as compared to molecules small in size and weight which validates the findings of the present study. The outcomes will ultimately be useful in designing better biomechanical exercise in combination with pharmaceutical agents to improve the bone health.