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Pediatr Emerg Care ; 34(9): e165-e167, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30180106

RESUMO

Lactic acidosis in the emergency department and other hospital settings is typically due to tissue hypoxia with sepsis being the most common cause. However, in patients with persistently elevated lactate without evidence of inadequate oxygen delivery, type B lactic acidosis should be considered. We report the case of a 12-year-old boy with relapsed and refractory pre-B-cell acute lymphoblastic leukemia who presented in distress with tachycardia, history of fever, and diffuse abdominal tenderness. The patient had severe metabolic acidosis with elevated lactate upon arrival to the emergency department. Despite aggressive fluid resuscitation and intravenous antibiotics, the patient's acidosis worsened. Serial blood cultures were negative, and he was eventually diagnosed with type B lactic acidosis secondary to relapsed acute lymphoblastic leukemia.


Assuntos
Acidose Láctica/etiologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações , Acidose Láctica/terapia , Antineoplásicos/efeitos adversos , Antineoplásicos/uso terapêutico , Criança , Estado Terminal/terapia , Diagnóstico Diferencial , Evolução Fatal , Humanos , Ácido Láctico/sangue , Masculino , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Sepse/diagnóstico , Tomografia Computadorizada por Raios X
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