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1.
Br J Neurosurg ; : 1-9, 2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38695277

RESUMO

BACKGROUND: Sacropelvic fractures with multidirectional instability require complex reduction and stabilisation techniques. Triangular osteosynthesis reconstruction is an established technique but hardware failure rates remain high and screw trajectories unfamiliar to spine surgeons. Our technique allows de-rotation of the pelvis, fracture reduction in both vertical and transverse planes, immediate weight bearing and is more reproducible for complex spine surgeons. OBJECTIVE: To describe our case series of dual triangular osteosynthesis reduction and stabilisation for complex sacropelvic fractures. METHODS: Retrospective case series of patients treated for unstable multiplanar sacropelvic fractures, at a level one trauma centre in the United Kingdom. Chart review was conducted to assess clinical features, radiology (plain radiographs, CT and MRI), surgical techniques and clinical and radiological outcomes. RESULTS: A total of six patients with four male and two females were included. Mean age of the cohort was 37.5 years (range 19-61 years) and average length of follow-up was 34.5 months (range 13-75 months). Three patients had neurological injury and three were intact. Four patients had associated thoraco-abdominal or lower limb injuries requiring intervention. All patients underwent surgery with reduction and stabilisation using dual triangular osteosynthesis constructs. At final follow-up, one patient had persistent bladder dysfunction (present preoperatively), one remained ASIA A from concomitant cord injury in the thoracic spine, and one patient with L5 and S1 weakness completely recovered. There were no metalwork complications and all patients achieved radiological fusion. CONCLUSION: Our technique of reduction and stabilisation of complex multidirectional sacropelvic fractures leads to a biomechanically strong construct with immediate stability, and without risk of hardware failure.

2.
World Neurosurg ; 135: e393-e404, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31821915

RESUMO

OBJECTIVE: Primary decompressive craniectomy (DC) is indicated to evacuate the hematoma and reduce intracranial pressure in traumatic brain injury (TBI). However, there are a myriad of complications because of absence of the bone flap. A novel technique, four-quadrant osteoplastic decompressive craniotomy (FoQOsD) retains the bone flap while achieving adequate cerebral decompression. METHODS: A single-center randomized controlled trial of 115 patients with TBI needing decompressive surgery was conducted. Of these patients, 59 underwent DC and 56 underwent FoQOsD. The primary outcome determined was functional status at 6 months using the Glasgow Outcome Scale-Extended. RESULTS: No significant differences were identified in baseline characteristics between both groups. Mean Glasgow Outcome Scale-Extended score was comparable at 6 months (4.28 in DC vs. 4.38 in FoQOsD; P = 0.856). Further, 22 of 58 patients in the DC group had died (38%) compared with 25 of 55 patients in the FoQOsD group (44.6%) (odds ratio [OR], 1.19; 95% confidence interval [CI], 0.6-2.36; P = 0.6) (1 patient lost to follow-up in each group). A favorable outcome was seen in 56.8% of patients in the DC group versus 54.4% of patients in the FoQOsD group (P = 0.74). Presence of intraventricular hemorrhage and subarachnoid hemorrhage (OR, 7.17; 95% CI, 1.364-37.7; P = 0.020), opposite side contusions (OR, 3.838; 95% CI, 1.614-9.131; P = 0.002) and anisocoria (OR, 3.235; 95% CI, 1.490-7.026; P = 0.003) preoperatively were individual factors that played a significant role in final outcome. CONCLUSIONS: FoQOsD is as efficacious as conventional DC with the added benefit of avoiding a second surgery. The procedure is associated with better cosmesis and fewer complications.


Assuntos
Lesões Encefálicas Traumáticas/cirurgia , Craniectomia Descompressiva/métodos , Adulto , Hemorragia Cerebral Intraventricular/etiologia , Feminino , Hematoma Subdural/etiologia , Humanos , Hemorragia Intracraniana Traumática/cirurgia , Hipertensão Intracraniana/prevenção & controle , Masculino , Hemorragia Subaracnóidea/etiologia , Resultado do Tratamento
3.
J Pediatr Neurosci ; 15(3): 304-307, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33531953

RESUMO

The development of secondary neoplasms following therapeutic cranial irradiation is rare and quite often lethal. Meningiomas, sarcomas, and high-grade gliomas are the most common tumors that manifest as a result of radiation therapy. We report the case of an 11-year-old child who presented with symptoms of supratentorial space-occupying lesion 7 years after curative surgery and cranial irradiation for a posterior fossa ependymoma. Magnetic resonance imaging of the brain revealed a right-sided temporoparietal dural-based contrast-enhancing lesion with evidence of overlying bone and skin involvement. The histological report of ependymoma from the previous surgery led us to suspect that we were dealing with a recurrence until the histopathology of the second surgery revealed highly malignant osteosarcoma. The child recovered fully and underwent chemotherapy, but ultimately succumbed to the disease. We report this case to highlight the importance of recognizing these neoplasms and to review its management.

4.
J Pediatr Neurosci ; 14(4): 228-231, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31908666

RESUMO

Glioblastoma (GBM) is an aggressive cancerous neoplasm of the brain that has numerous morphological subtypes. Primitive neuroectodermal differentiation (hereafter, referred to as embryonal tumor [ET] differentiation) in GBM is one of them and is known to occur in adults. Their presentation in pediatric population is rare and can be a source of diagnostic confusion. The dual pathology leads to doubts where one could ask whether it is ET differentiation in GBM specimen or glial differentiation in ET specimen. This histological discrimination has a bearing on the treatment regimens and prognosis. We report a case of a 10-year-old boy presenting with a supratentorial GBM, isocitrate dehydrogenase wild type with ET differentiation, and multiple benign bony lesions of both extremities. He underwent surgical excision for the brain neoplasm followed by radiotherapy and has shown prolonged survival with no recurrence. In this article, we discuss prognostic factors associated with long-term survival of these tumors.

5.
J Pediatr Neurosci ; 12(3): 285-287, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29204210

RESUMO

Abdominal complications after ventriculoperitoneal (VP) shunt surgery for hydrocephalus have been known to occur. The more common complications include peritoneal pseudocyst, obstruction of the lower end, and shunt infection. Perforations of the intra-abdominal hollow viscera leading to spontaneous extrusions of the peritoneal catheter via the natural orifices have also been reported. A rarer phenomenon still is the migration of the lower end of the VP shunt through the anterior abdominal wall, leading to the formation of a spontaneous umbilical fistula at a site unrelated to the surgical site. Eight cases have been described in the literature so far with various causes elucidated. We report this condition in a child 4.5 years after his shunt surgery and postulate different mechanisms for both early and late presentations of this condition.

6.
J Pediatr Neurosci ; 10(3): 261-3, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26557171

RESUMO

Decompressive craniotomy (DC) is used to treat intracranial hypertension associated with traumatic brain injury. Early DC is associated with better outcomes. We present a neonate with a history of fall with computed tomography scan showing a large frontoparietal contusion and associated parietal and temporal bone fracture. This acted as a spontaneous DC causing bony segment to separate due to which the edematous brain could be accommodated. Despite the presence of a large contusion, the child was neurologically intact and medically managed. The neonate presented with a posttraumatic leptomeningeal cyst 2 months later, which had to be repaired surgically. We discuss how a linear undisplaced fracture acts as spontaneous DC and the role of early DC in improving outcomes.

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