Evaluation of in vivo properties of Velosorb™ fast versus Vicryl™ rapide in a functional rabbit model of intradermic suture and episiotomy.

OBJECTIVE: Fast-absorbing polyglactin 910 is commonly used to suture skin and vaginal incisions. In vitro studies have shown similar tensile strength properties between Velosorb™ Fast and Vicryl™ Rapide (Al-Qattan MM. J Hand Surg Br Eur. 2005;30(1):90-91). This randomized study compared Velosorb™ Fast (Covidien) with Vicryl™ Rapide (Ethicon) in a rabbit model of intradermic suture and episiotomy. MATERIALS AND METHODS: This randomized prospective study was performed on 20 New Zealand rabbits, in which we realized a mediolateral perineo-vaginal incision and two vertical skin incisions of about 8 cm on the abdominal wall. The sutures were randomized between Velosorb™ Fast (Covidien) and Vicryl™ Rapide (Ethicon), and each rabbit was treated with the same suture on both vaginal incision and left abdominal incision, while the right abdominal incision was closed with an alternate suture. A macroscopic examination was performed on days 5 and 11. On day 11, animals were sacrificed for histological (Badylak quantitative score) and electron microscopic examinations. Differences were considered significant at p < .05. RESULTS: All of the rabbits survived and were included in the final results. Fifty-one sutures were visible by histologic analysis (27 in the Velosorb™ Fast group and 24 in the Vicryl™ Rapide group). The power of the study was ≥80%. There was no significant difference between the two groups based on the total histologic Badylak score analysis or the Badylak sub-score analysis. CONCLUSIONS: Velosorb™ Fast seems to be as efficient as Vicryl™ Rapide for use in perineal and skin closure.

Malassezia pachydermatis en lesiones de piel en pacientes de la Quinta región de Chile / Malassezia pachydermatis on skin lesions in patients from the Fifth region of Chile

Introducción: M. pachydermatis es una levadura zoofílica que puede provocar pitiriasis versicolor y dermatitis seborreica. Objetivos: determinar la presencia de M. pachydermatis en pacientes con pitiriasis versicolor y dermatitis seborreica, además de evaluar el rendimiento del examen microscópico directo y cultivo, en estas infecciones. Materiales y Método: estudio descriptivo prospectivo realizado en el Hospital Carlos van Buren de Valparaíso, Chile, durante el período 2011-2013. Se seleccionaron pacientes con diagnóstico clínico de pitiriasis versicolor y dermatitis seborreica. La confirmación micológica fue realizada con examen microscópico directo y/o cultivo, además de pruebas especiales. Resultados: ingresaron al estudio 66 pacientes. El 60,6% fueron hombres, con un promedio de edad de 43 años. El 70% con VIH (+). El 90,9% presentó pitiriasis versicolor (principalmente hipopigmentadas en el tronco) y el 9% dermatitis seborreica. El examen microscópico directo fue positivo en el 95,4% de los casos y en el 62,12% de los cultivos. La especie más frecuente fue M. pachydermatis, seguida por M. furfur. Del total de pacientes: 50 se trataron por vía tópica, 15 con tópico más sistémico y 1 no fue tratado. Conclusiones: la mayoría de los pacientes ingresados a este estudio fueron hombres, VIH(+) y con lesiones de pitiriasis versicolor hipopigmentadas de tronco. La especie más frecuente fue M. pachydermatis. El tratamiento tópico fue el más indicado.

Introduction: M. pachydermatis is a zoophilic yeast that can cause pityriasis versicolor and seborrheic dermatitis. Objectives: to determine the presence of M. pachydermatis in patients with pityriasis versicolor and seborrheic dermatitis, in addition to evaluating the performance of direct microscopic examination and culture in these infections. Materials and Method: a prospective descriptive study conducted in the Carlos van Buren Hospital in Valparaíso, Chile, during the period 2011-2013. Patients with clinical diagnosis of pityriasis versicolor and seborrheic dermatitis were selected. Mycological confirmation was made with direct microscopic examination and / or culture, and special tests. Results: 66 patients entered the study. 60.6% were men, with an average age of 43 years. 70% with HIV (+). 90.9% had pityriasis versicolor (mostly hypopigmented in the trunk) and seborrheic dermatitis 9%. Direct microscopic examination was positive in 95.4% of cases and 62.12% of the cultures. The most frequent species was M. pachydermatis, followed by M. furfur. Of the patients: 50 were treated topically with 15 more systemic plus topical and 1 was untreated. Conclusions: most patients admitted to this study were men, HIV (+) and hypopigmented pityriasis versicolor lesions in the trunk. The most frequent species was M. pachydermatis. Topical treatment was the most appropriate.

[A case of digestive occlusion on an endometriosis lesion after treatment by GnRH agonist]. / Un cas d'occlusion digestive sur lésion d'endométriose sous agoniste de la GnRH.

Endometriosis concerns 10% of childbearing age women and frequently affects the digestive tract. We report here the case of a 31-year-old patient presenting a severe occlusive syndrome while being treated with GnRH agonist, within the framework of an in vitro fertilization. The surgical treatment will find a deep endometriosis affecting the sigmoid and colorectal junction and leading to a colorectal resection. These endometriosis lesion recurrences during ovarian stimulation or by GnRH flare up effect is rare and often debated. The surgical treatment of the lesions, before the medically assisted procreation, seems to prevent these complications.