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Chirurgia (Bucur) ; 115(5): 585-594, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33138895

RESUMO

PURPOSE: The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days after surgery. The primary goal was patient's complete healing and the evaluation of incontinence and recurrence rate; the secondary goal included the evaluation of manometry parameters, symptom relief and complications related to nifedipine and lidocaine administration. Results: All wounds healed within 40 days after surgery. We didn't observe any de novo postoperative anal incontinence case. We reported 2 cases of recurrences, healed after conservative therapy. We didn't report any local complications related to the administration of the ointment therapy; with whom all patients reported a good compliance. Conclusions: Fissurectomy and anoplasty with V-Y cutaneous advancement flap and topical administration of nifedipine and lidocaine, is an effective treatment for CAPF with IAS hypertonia.


Assuntos
Canal Anal/efeitos dos fármacos , Bloqueadores dos Canais de Cálcio/administração & dosagem , Fissura Anal , Hipertonia Muscular/tratamento farmacológico , Nifedipino , Administração Tópica , Canal Anal/cirurgia , Anestésicos Locais/administração & dosagem , Doença Crônica , Terapia Combinada , Fissura Anal/complicações , Fissura Anal/tratamento farmacológico , Fissura Anal/cirurgia , Humanos , Lidocaína , Hipertonia Muscular/complicações , Hipertonia Muscular/cirurgia , Nifedipino/administração & dosagem , Pomadas/administração & dosagem , Estudos Prospectivos , Retalhos Cirúrgicos , Resultado do Tratamento
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