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Ned Tijdschr Geneeskd ; 1662022 08 09.
Artigo em Holandês | MEDLINE | ID: mdl-36036687

RESUMO

The author comments on a report in The Lancet of a conference in London in 2019 regarding miscarriages. Key-message of the meeting: "There is no high-quality evidence for any treatment to prevent miscarriages in women at high risk of miscarriage"Thisstatement seems to mark the end of an era.Around 1930 estrogenes and progesteron were isolated. Both were recognized as extremely important in pregnancy, and therefore used as a treatment for "Habitual Abortion", or "Recurrent Miscarriage". Numerous attempts with very different treatments followed. None of these, however, produced reliable positive results. Although most research focussed on treatment of the woman, over 90% of the miscarriages is caused by abnormalities of the embryo: anembryonic amnionsacs, aneuploidy, closuredefects of the cerebrospinal system, etc. Malformed embryos, however, should not be included in trials. Live-birth-rates in women continuing their attempts are high. Providing these people with moral support including the right information is preferable over accelerating on a dead end.


Assuntos
Aborto Habitual , Aborto Espontâneo , Aborto Habitual/prevenção & controle , Aborto Espontâneo/prevenção & controle , Feminino , Humanos , Gravidez , Progesterona
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