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1.
Sci Data ; 11(1): 321, 2024 Mar 28.
Artigo em Inglês | MEDLINE | ID: mdl-38548727

RESUMO

Flexible bronchoscopy has revolutionized respiratory disease diagnosis. It offers direct visualization and detection of airway abnormalities, including lung cancer lesions. Accurate identification of airway lesions during flexible bronchoscopy plays an important role in the lung cancer diagnosis. The application of artificial intelligence (AI) aims to support physicians in recognizing anatomical landmarks and lung cancer lesions within bronchoscopic imagery. This work described the development of BM-BronchoLC, a rich bronchoscopy dataset encompassing 106 lung cancer and 102 non-lung cancer patients. The dataset incorporates detailed localization and categorical annotations for both anatomical landmarks and lesions, meticulously conducted by senior doctors at Bach Mai Hospital, Vietnam. To assess the dataset's quality, we evaluate two prevalent AI backbone models, namely UNet++ and ESFPNet, on the image segmentation and classification tasks with single-task and multi-task learning paradigms. We present BM-BronchoLC as a reference dataset in developing AI models to assist diagnostic accuracy for anatomical landmarks and lung cancer lesions in bronchoscopy data.


Assuntos
Broncoscopia , Neoplasias Pulmonares , Humanos , Inteligência Artificial , Neoplasias Pulmonares/diagnóstico por imagem , Tórax/diagnóstico por imagem , Pontos de Referência Anatômicos/diagnóstico por imagem
2.
Appl Bionics Biomech ; 2023: 8843488, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37780200

RESUMO

Objective: To localize and distinguish between benign and malignant tumors on MRI. Method: This work proposes a high-performance method for brain tumor feature extraction using a combination of complex network and U-Net architecture. And then, the common machine-learning algorithms are used to discriminate between benign and malignant tumors. Experiments and Results. The dataset of brain MRI of a total of 230 brain tumor patients in which 77 high-grade glioma patients and 153 low-grade glioma patients were processed. The results of classifying benign and malignant tumors achieved an accuracy of 99.84%. Conclusion: The high accuracy of experiment results demonstrates that the use of the complex network and U-Net architecture can significantly improve the accuracy of brain tumor classification. This method could potentially be useful for clinicians in aiding diagnosis and treatment planning for brain tumor patients.

3.
Med Image Anal ; 78: 102422, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-35339951

RESUMO

Multiphase CT scanning of the liver is performed for several clinical applications; however, radiation exposure from CT scanning poses a nontrivial cancer risk to the patients. The radiation dose may be reduced by determining the scan range of the subsequent scans by the location of the target of interest in the first scan phase. The purpose of this study is to present and assess an automatic method for determining the scan range for multiphase CT scans. Our strategy is to first apply a CNN-based method for detecting the liver in 2D slices, and to use a liver range search algorithm for detecting the liver range in the scout volume. The target liver scan range for subsequent scans can be obtained by adding safety margins achieved from Gaussian liver motion models to the scan range determined from the scout. Experiments were performed on 657 multiphase CT volumes obtained from multiple hospitals. The experiment shows that the proposed liver detection method can detect the liver in 223 out of a total of 224 3D volumes on average within one second, with mean intersection of union, wall distance and centroid distance of 85.5%, 5.7 mm and 9.7 mm, respectively. In addition, the performance of the proposed liver detection method is comparable to the best of the state-of-the-art 3D liver detectors in the liver detection accuracy while it requires less processing time. Furthermore, we apply the liver scan range generation method on the liver CT images acquired from radiofrequency ablation and Y-90 transarterial radioembolization (selective internal radiation therapy) interventions of 46 patients from two hospitals. The result shows that the automatic scan range generation can significantly reduce the effective radiation dose by an average of 14.5% (2.56 mSv) compared to manual performance by the radiographer from Y-90 transarterial radioembolization, while no statistically significant difference in performance was found with the CT images from intra RFA intervention (p = 0.81). Finally, three radiologists assess both the original and the range-reduced images for evaluating the effect of the range reduction method on their clinical decisions. We conclude that the automatic liver scan range generation method is able to reduce excess radiation compared to the manual performance with a high accuracy and without penalizing the clinical decision.


Assuntos
Processamento de Imagem Assistida por Computador , Radioisótopos de Ítrio , Humanos , Processamento de Imagem Assistida por Computador/métodos , Fígado/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos
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