Beyond screening in primary practice settings: Time to stop fiddling while Rome is burning.

OBJECTIVE: This forum presents the current state of research in the screening and identification of people with eating disorders in community and primary care, taking a longer-term perspective that highlights the slow rate of progression in development of instruments, and impact on polices and practice. METHOD: An historical overview is presented, followed by a critique of contemporary instruments and practice, and barriers to case detection and appropriate referral pathways. RESULTS: There are now many instruments but all lack high levels of positive predictive power. However, some do have high sensitivity. Barriers contributing to poor detection and the treatment gap include need for improved education and support for primary care professionals and lack of confidence of individuals with eating disorders to initiate a discussion with health professionals. The best screening instrument would not overcome either of these barriers. DISCUSSION: We purport there is an urgent need to improve current screening instruments (not to develop more), particularly those with high sensitivity. These should be being employed alongside programs to both improve primary care professionals' skills in assessment and management of people with eating disorders, and to empower consumers to navigate care pathways. PUBLIC SIGNIFICANCE STATEMENT: We argue that further screening instruments for eating disorders are not needed. Rather, it is more urgent to have a greater research focus on how to encourage primary care workers to ask about eating and body image and how to best translate that to more individuals with eating disorders being offered treatment. This work needs to be linked with tools that empower consumers to navigate care pathways.

The relationship between disordered eating and cigarette smoking among adult female twins.

OBJECTIVE: While previous studies have shown a link between cigarette smoking and disordered eating (DE), it is less clear whether this association can be explained by attempts to control weight and/or temperament. This study had two aims: to examine weight/shape and DE symptomatology associated with weight control-related smoking and disordered eating; second, to investigate whether temperament-based factors explain the association between compensatory smoking and weight and shape-related characteristics, and disordered eating symptoms. METHOD: Female twins (N = 1,002) from the Australian Twin Registry, aged 28-39 years, were assessed by interview yielding lifetime diagnostic information of disordered eating and use of cigarette smoking for weight control. Self-report measures of temperament were available. RESULTS: Women who had never smoked (50.6%, n = 495) or had smoked for reasons other than weight and shape control (42.5%, n = 415) were generally not differentiated with respect to indicators of disordered eating. Women who smoked for reasons primarily associated with weight and shape control (6.9%, n = 67) had significantly higher levels of disordered eating than non-smokers identified as being higher levels of purging (OR = 4.55, 95% CI = 2.41-8.59) and fasting (OR = 9.32, 94% CI = 4.43-19.90) but not objective binge episodes (OR = 1.69, 95% CI = 0.71-3.99). Of those women diagnosed with lifetime eating disorders, weight-control smokers had higher levels of purging (OR = 4.22, 95% CI = 1.13-15.80) than those who did not. There were no differences in temperament. DISCUSSION: Results support co-occurrence of smoking for weight control and purging in both community and clinical groups, and indicate this association is related to weight control and not temperament.

A randomised pilot of a self-help workbook intervention for breast cancer survivors.

PURPOSE: The aim of this study is to evaluate the efficacy of a self-help workbook for improving adjustment for breast cancer survivors. METHODS: An RCT compared the workbook (n = 20) with no-workbook controls (n = 20). Coping, traumatic stress and quality of life were measured at baseline, then 3 and 6 months later. RESULTS: No interactions were found. A significant group main effect was found for venting coping; controls used less venting coping than workbook participants (p = 0.034). A significant time main effect was obtained for cognitive functioning (p = 0.003). Reliable change indices showed a trend towards a protective effect across all coping measures for workbook participants compared to controls. Qualitative feedback suggested that participants felt well supported by the intervention, but would have preferred receiving it during treatment. CONCLUSIONS: While trends showed some promise for improving coping, endorsement for the workbook was not obtained. The difficulties encountered in recruiting survivors and the resulting implications regarding the feasibility of offering self-help resources to this population are discussed.

A randomised controlled trial to evaluate the effects of a self-help workbook intervention on distress, coping and quality of life after breast cancer diagnosis.

OBJECTIVE: To evaluate the efficacy of an interactive self-help workbook in reducing distress, and improving quality of life (QOL) and coping for women recently diagnosed with breast cancer. DESIGN: Randomised controlled trial comparing the use of the workbook and that of an information booklet. PARTICIPANTS AND SETTING: 49 women with Stage 0 to II breast cancer diagnosed in the previous month and recruited from 1 February 2007 to 1 February 2008, in two urban Australian public hospitals. MAIN OUTCOME MEASURES: The primary outcome measures were depression, anxiety, and posttraumatic stress. Secondary outcomes included QOL, body image, and the coping styles helplessness/hopelessness, cognitive avoidance and anxious preoccupation. RESULTS: After controlling for baseline levels, interactions at 3-month follow-up showed that participants in the workbook group had significantly lower levels of posttraumatic stress (F[1,89] = 7.01; P = 0.01), helplessness/hopelessness (F [1,89] = 4.75; P = 0.03), and cognitive avoidance (F [1,89] = 4.95; P = 0.03) than those in the control (information booklet) group. However, women in the workbook group had significantly poorer body image than those in the control group (F [1,89] = 6.43; P = 0.01). At 6 months, only the body image interaction remained significant (F [1,93] = 7.44; P = 0.01). CONCLUSION: These results suggest that a self-help workbook can be an effective, short-term intervention for improving posttraumatic stress, cognitive avoidance, and certain depressive symptoms in women recently diagnosed with breast cancer. However, issues related to body image need to be dealt with differently. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry

A prospective examination of perceived stress as a mediator of the relationship between life-events and QOL following breast cancer.

OBJECTIVES: This study prospectively investigated the relationship between life-events, perceived stress, and quality of life (QOL) following breast cancer diagnosis, using the bio-behavioural model of cancer stress as a framework. DESIGN: A longitudinal, self-report design was used. METHODS: Three waves of data from 10,543 mid-aged Australian women (aged 45-50 at Survey 1) were collected over 5 years as part of a population-based survey. From this group a subsample (N=140) were identified who did not have breast cancer at Survey 1, but who subsequently developed breast cancer. Random regression growth curve analyses were used to investigate whether perceived stress mediated the relationship between initial life-events and change in QOL functioning overtime. RESULTS: Prospective evidence was generated for each of the three criteria for testing mediation. As the number of life-events before breast cancer increased, women were significantly more likely to experience corresponding increases in perceived stress over the 5-year period. As the level of perceived stress before breast cancer increased, women were more likely to experience deteriorations overtime in role emotional, role physical, vitality, bodily pain, physical functioning, and social functioning. As the number of life-events before breast cancer increased, women were at significant risk of experiencing deteriorations overtime in bodily pain, social functioning, role emotional, and vitality. Mediational analyses revealed that perceived stress fully mediated the relationship between initial life-events and two QOL domains; role-emotional and social functioning. CONCLUSION: Results partially supported the bio-behavioural model of cancer stress, but the model does not appear to fit the data as well as predicted, and may require revision.

An examination of the overlap between genetic and environmental risk factors for intentional weight loss and overeating.

OBJECTIVE: To further our understanding of how intentional weight loss (IWL) and overeating are related, we examined the shared genetic and environmental variance between lifetime IWL and overeating. METHOD: Interview data were available for 1,976 female twins (both members of 439 and 264 pairs of monozygotic and dizygotic twins, respectively), mean age = 40.61, SD = 4.72. We used lifetime diagnostic data for eating disorders obtained from a semistructured psychiatric telephone interview, examined in a bivariate twin analysis. Both lifetime behaviors were measured on a 3-point scale, where absence of IWL or overeating formed one anchor on the scale and lifetime anorexia nervosa (AN) and bulimia nervosa (BN) formed the opposite anchors, respectively. RESULTS: In line with previous findings, a higher body mass index was significantly associated with the lifetime presence of IWL and/or overeating (odds ratio = 1.13, 95% confidence interval (CI): 1.08-1.19). The best fitting twin model contained additive genetic and nonshared environmental influence influencing both IWL and overeating, with correlations between these influences of 0.61 (95% CI: 0.35-0.92) and 0.24 (95% CI: 0.07-0.42), respectively. DISCUSSION: About 37% of genetic risk factors were considered to overlap between IWL and overeating, and with only 6% of overlap between environmental risk factors. Thus, considerable independence of risk factors was indicated.

The psychosocial concerns and needs of women recently diagnosed with breast cancer: a qualitative study of patient, nurse and volunteer perspectives.

OBJECTIVE: To qualitatively identify the concerns and needs of Australian women recently diagnosed with breast cancer. BACKGROUND: Breast cancer diagnosis can lead to impairment in multiple areas of psychosocial well-being, including physical, social and emotional functioning. Research has therefore begun to focus on identifying and addressing survivors' concerns and needs, with most research examining the time of treatment completion. However diagnosis and treatment are also key times of psychological need, and less is known about the psychosocial concerns and needs at these times. RESEARCH DESIGN: Seven focus group interviews were conducted examining three categories of participants: (i) patients diagnosed with early-stage breast cancer within the past 12 months, (ii) oncology nurses, and (iii) volunteers who work with cancer patients. Sampling was discontinued when informational redundancy was achieved. SETTING AND PARTICIPANTS: Thirty-four participants took part in one of seven focus group meetings held in a hospital patient resource room. RESULTS: A wide variety of psychosocial concerns and needs were discussed, and five specific areas of concern were identified: (i) coping with side-effects; (ii) dealing with self-concept change; (iii) stress and adjustment reactions; (iv) having to manage others' unhelpful beliefs, expectations and emotions; and (v) issues with survival and growth. There was a large degree of consistency in the concerns and needs identified by the different group categories. CONCLUSION: In general, the concerns and needs expressed were consistent with survivorship issues previously identified in the literature; however, several new insights were obtained. Clinical implications of these findings are discussed.

Longitudinal risk factors for adverse psychological functioning six months after coronary artery bypass graft surgery.

This research aimed to identify modifiable risk factors for poor psychological functioning six months post-operatively, using a chronic illness model to explain the relationships between risk factors. Consecutive elective CABG patients (N = 119) completed self-report measures including optimism, illness representations, self-rated health, social support, coping methods, depression, anxiety and PTSD symptomatology in a repeated measures design. Poor pre-operative psychological functioning was the strongest psychological risk factor for adverse psychological functioning six months post-operatively. Longitudinal support for the chronic illness model examined was limited. Further research to identify modifiable risk factors and pre-operative psychopathology screening to determine individuals at-risk of poor psychological outcome is recommended.

Psychological risk factors for cardiac-related hospital readmission within 6 months of coronary artery bypass graft surgery.

OBJECTIVE: The objective of this study was to examine the psychological risk factors for cardiac-related readmission within 6 months of coronary artery bypass graft surgery (CABG). METHODS: Consecutive patients awaiting elective CABG (N=119; 100 males and 19 females), with a mean age of 63.3 years, completed a battery of psychosocial measures in a three-stage repeated-measures design. Relevant medical data were also extracted from patients' medical records 6 months postoperatively to allow for the examination of potential covariates. RESULTS: Two psychological variables, increased postoperative anxiety and increased preoperative depression, were identified as risk factors for cardiac-related readmission independent of the only significant covariate identified, cardiopulmonary bypass time. CONCLUSION: Anxiety in the immediate postoperative period and, to a lesser extent, preoperative depression are important determinants of health care utilization postdischarge. Further research to clarify the psychological factors that are predictive of readmission, and that attempt to determine both the underlying cause of readmissions and potential mechanisms through which psychological factors act is recommended. Such research may highlight potential factors to target in interventions and the best time at which to intervene.

Application of a chronic illness model as a means of understanding pre-operative psychological adjustment in coronary artery bypass graft patients.

OBJECTIVES: To increase understanding of the factors associated with pre-operative psychological adjustment in coronary artery bypass graft (CABG) patients by assessing the utility of a chronic illness model developed by Scharloo, Kaptein, Weinman, Willems, and Rooijmans (2000). DESIGN: A cross-sectional design was employed. METHOD: Elective CABG patients (N=119) completed self-report measures of illness representation, self-rated health, social support, coping methods, and pre-operative adjustment (depression and post-traumatic stress disorder (PTSD) symptomatology) an average of 30 days prior to surgery. Hierarchical multiple regression was used to assess the mediational relationships proposed by the chronic illness model. RESULTS: Five 3-variable mediational chains were assessed. In all instances, the results conformed to the relationships suggested by the chronic illness model where the strength of the relationship between the independent and dependent variables was reduced when the mediator variable was controlled. However, a significant reduction of this relationship was found in three of the five chains examined. The most rigorous support for the model occurred, where increased use of avoidance coping mediated the relationship between poorer self-rated health and increased PTSD symptomatology, and also where increased use of avoidance coping partially mediated the relationship between a more negative illness representation and increased PTSD symptomatology, and poorer self-rated health and increased depression. CONCLUSIONS: The chronic illness model of Scharloo and colleagues shows potential in explaining pre-operative adjustment in CABG patients. Longitudinal examination of the model is recommended.

Psychological risk factors for increased post-operative length of hospital stay following coronary artery bypass graft surgery.

To date, researchers have examined the role of psychological factors in longer-term adaptation to coronary artery bypass graft surgery (CABG), but few have investigated the role of such factors in the immediate post-operative period. Thus, the current study examined psychological risk factors for increased post-operative length of hospital stay in 119 consecutive elective CABG patients (100 men and 19 women). When controlling for operative/post-operative factors, medical factors accounted for 24.5% of the variance. However, pre-operative psychological factors accounted for a further 4.4% of the variance, with increased depression and lower PTSD symptomatology identified as significant independent risk factors for longer post-operative length of hospital stay. Hence, while post-operative length of hospital stay is largely determined by medical factors, psychological factors also influence this outcome. Further research is required to replicate the current findings and to determine the mechanisms through which these variables may act.

The impact of breast cancer on the lives of middle-aged women: results from the Australian longitudinal study of women's health.

This article investigated the impact of breast cancer (BC) in middle-aged Australian women (45-50 years). Two waves of data collected 2 years apart from a longitudinal survey of 12,177 women identified 3 groups: (a) 11,933 (98%) who reported never having had BC, (b) 181 (1.5%) who reported a diagnosis of BC at Time 1, and (c) 63 (0.5%) who reported onset of BC between Time 1 and Time 2. Repeated measures analysis of variance was used to compare the 3 groups. Women with recent onset of BC experienced significant changes across a range of functioning compared with the other 2 groups. Compared with women with no BC, women with longer established onset of BC had significantly worse health and social outcomes, but these were associated with small effect sizes. Both groups of women with BC reported less impact on mental and emotional health than on other areas of functioning.

Predicting worries about health after breast cancer surgery.

Given the widespread worries about future health in women with breast cancer, it is important to understand the predictors of such fear so that possible avenues for intervention can be formulated. In this longitudinal study of 44 women who had undergone breast cancer surgery, we look at demographic variables, cancer and treatment related symptoms, and denial coping measured post-surgery and their ability to predict future health fears at 6-weeks and 12-weeks post-surgery. At both follow-up periods, around 1 in 5 women had strong worries about their future health, and post-surgery future health fears significantly predicted future health fears. In a hierarchical multiple regression, controlling for post-surgery health fears, future health fears at both follow-up periods were predicted only by denial coping. Cross-lag analyses suggested that these relationships were causal. Findings suggest that denial coping is a powerful predictor of future health fears, with this relationship growing stronger over time. Future research should investigate which interventions can decrease denial, and whether this then decreases health fears in the aftermath of breast cancer surgery.

The measurement of coping responses: validity of the Billings and Moos Coping Checklist.

OBJECTIVE: The primary aim of the study was to investigate the factor structure and psychometric properties of the modified Coping Checklist. METHODS: Self-report questionnaires asking about coping responses and mental health were administered to 515 undergraduate university students and to 119 patients awaiting elective coronary artery bypass graft surgery. Confirmatory (CFA) and exploratory factor analyses (PCA) were used to summarize and describe coping responses. RESULTS: CFA indicated that the subscale structure originally proposed for the Coping Checklist did not adequately fit the data. Subsequent PCA resulted in four factors: (1) Positive reappraisal; (2) Seeking support; (3) Avoidance; and (4) Information seeking. Internal consistencies ranged between .41 and .62 and 12-week test-retest reliability ranged between .59 and .71. Evidence for the concurrent validity of the solution generated by PCA was demonstrated by low to moderate correlations between the four factors identified and demographic and psychosocial measures. CONCLUSION: Even with modifications to the Coping Checklist, it is recommended that researchers investigate alternative methods of assessing coping responses in health psychology settings.