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1.
Phys Med Biol ; 48(19): 3143-55, 2003 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-14579857

RESUMO

Of the biological effects of human exposure to radiofrequency and microwave radiation, the best-established are those due to elevation of tissue temperature. To prevent harmful levels of heating, restrictions have been proposed on the specific absorption rate (SAR). However, the relationship between SAR and temperature rise is not an invariant, since not only the heat capacity but also the efficiency of heat dissipation varies between different tissues and exposure scenarios. For small enough SAR, the relationship is linear and may be characterized by a 'heating factor' deltaT/SAR. Under whole-body irradiation the SAR may be particularly high in the ankles due to the concentration of current flowing through a relatively small cross-sectional area. In a previous paper, the author has presented calculations of the SAR distribution in a human leg in the high frequency (HF) band. In this paper, the heating factor for this situation is derived using a finite element approximation of the Pennes bioheat equation. The sensitivity of the results to different blood perfusion rates is investigated, and a simple local thermoregulatory model is applied. Both time-dependent and steady-state solutions are considered. Results confirm the appropriateness of the ICNIRP reference level of 100 mA on current through the leg, but suggest that at higher currents significant thermoregulatory adjustments to muscle blood flow will occur.


Assuntos
Temperatura Corporal/fisiologia , Temperatura Corporal/efeitos da radiação , Campos Eletromagnéticos , Perna (Membro)/fisiologia , Perna (Membro)/efeitos da radiação , Modelos Biológicos , Ondas de Rádio , Radiometria/métodos , Carga Corporal (Radioterapia) , Simulação por Computador , Impedância Elétrica , Transferência de Energia/fisiologia , Análise de Elementos Finitos , Humanos , Perna (Membro)/irrigação sanguínea , Doses de Radiação , Eficiência Biológica Relativa , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
2.
Phys Med Biol ; 44(4): 1041-52, 1999 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-10232813

RESUMO

Protection standards for radiofrequency electromagnetic radiation are principally intended to avoid detrimental thermal effects. To this end the International Commission on Non-Ionizing Radiation Protection (ICNIRP), and national bodies such as the National Radiological Protection Board (NRPB), recommend limitations on the localized specific energy absorption rate (SAR) in various parts of the body. The role of numerical dosimetry is to estimate the SAR from measurable parameters such as external field strengths and total body currents. In recent years there have been significant advances in the sophistication of the anatomical models available, and in our knowledge of the electrical properties of the body tissues. Several groups, including NRPB, have developed mathematical phantoms from medical imaging data, such as MRI scans. It has been known for some time that under certain circumstances SAR restrictions may be violated in the ankle due to the concentration of current in a small area. In this paper the author presents calculations of the SAR distribution in a human leg in the high-frequency (HF) band. This band contains the human whole-body resonance frequency and therefore gives the strongest coupling of the body to the field. The present study uses a finite element model with variable mesh size, derived from a 2 mm resolution voxel phantom of the whole body. It also uses recently acquired data on the electrical properties of the tissues. The results are discussed in the light of the exposure standards promulgated by national and international bodies such as NRPB and ICNIRP, and it is shown that the basic SAR restrictions in the leg are ensured by a current reference level of 100 mA.


Assuntos
Absorciometria de Fóton/métodos , Perna (Membro)/diagnóstico por imagem , Imagens de Fantasmas , Planejamento da Radioterapia Assistida por Computador/métodos , Humanos , Modelos Estatísticos
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