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1.
Radiat Environ Biophys ; 61(1): 87-109, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34816291

RESUMO

The cohorts of people formerly living at the Techa River shoreline in the Southern Urals, Russia, are widely studied cohorts for the investigation of low-dose radiation effects to human health. The nuclear facilities of the Mayak Production Association (PA) discharged their radioactive effluents into the nearby Techa River, especially in the first years of operation. Health status of cohort member data is constantly being improved and updated. Consequently, there is a need to also improve and verify the underlying dosimetry, which gives information about the dose of cohort members. For the Techa River population, the dosimetry is handled in the Techa River Dosimetry System (TRDS). The present work shows results of a feasibility study to validate the TRDS at the location of the village of Metlino, a village just 7 km downstream from the Mayak PA. For this settlement there were two sources of external exposure, the contaminated banks of the Techa River and the contaminated shoreline of the nearby Metlinsky Pond. In the present study the north-western wall of a granary was used as a dose archive to validate dose estimates. Measurements of doses in brick accumulated over many decades and measurements of the current dose rate in bricks were combined with dose rate measurements in air above ground in front of the granary, historical contamination data and Monte-Carlo simulations. Air kerma estimates for 1949-1956 significantly different from zero could not be reconstructed for the Metlinsky Pond shoreline near the granary, but an upper dose limit could be estimated. Implications for TRDS-2016 are discussed.


Assuntos
Resíduos Radioativos , Poluentes Radioativos da Água , Humanos , Medições Luminescentes , Lagoas , Resíduos Radioativos/análise , Rios , Federação Russa , Poluentes Radioativos da Água/análise
2.
J Radiol Prot ; 40(4)2020 Nov 11.
Artigo em Inglês | MEDLINE | ID: mdl-33059345

RESUMO

The reconstruction of the Cochabamba (Bolivia) radiological incident (IAEA-International Atomic Energy Agency 2004 The Radiological Accident in Cochabamba STI/PUB/1199 (Vienna: IAEA)) was used to assess and evaluate retrospective dosimetry methodologies. For this purpose an unshielded radioactive source was placed inside a transportation vehicle (bus) resembling a radiological exposure device. External doses were assessed using water and anthropomorphic phantoms that were placed at various positions in the vehicle and equipped with both fortuitous dosimeters (chip cards, mobile phones), individual dosimeters (electronic dosimeters, thermoluminescent and optically stimulated luminescence dosimeters) and in three cases also with blood sample tubes in thermos flasks for cytogenetic methods. This paper gives a detailed description of the experimental setup, the results of the reference dosimetry, including organ dose assessment for the phantom closest to the source, and includes a compilation of the main results obtained by the retrospective dosimetry techniques. Comparison is made to the results of dose reconstruction obtained by IAEA during the response to the Cochabamba incident in 2002.


Assuntos
Incidentes com Feridos em Massa , Triagem , Imagens de Fantasmas , Doses de Radiação , Radiação Ionizante , Radiometria/métodos , Estudos Retrospectivos
3.
Radiat Environ Biophys ; 58(4): 539-552, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31346699

RESUMO

Current radiological emergency response recommendations have been provided by the International Commission on Radiological Protection and adopted by the International Atomic Energy Agency in comprehensive Safety Standards. These standards provide dose-based guidance for decision making (e.g., on sheltering or relocation) via generic criteria in terms of effective dose in the range from 20 mSv per year, during transition from emergency to existing exposure situation, to 100 mSv, acute or annual, in the urgent phase of a nuclear accident. The purpose of this paper was to examine how such dose reference levels directly translate into radiation-related risks of the main stochastic detrimental health effects (cancer). Methodologies, provided by the World Health Organization after the Fukushima accident, for calculating the lifetime and 20 year cancer risks and for attributing relevant organ doses from effective doses, have been applied here for this purpose with new software, designed to be available for use immediately after a nuclear accident. A new feature in this software is a comprehensive accounting for uncertainty via simulation technique, so that the risks may now be presented with realistic confidence intervals. The types of cancer risks considered here are time-integrated over lifetime and the first 20 years after exposure for all solid cancers and either the most radiation-sensitive types of cancer, i.e., leukaemia and female breast cancer, or the most radiation-relevant type of cancer occurring early in life, i.e., thyroid. It is demonstrated here how reference dose levels translate differently into specific cancer risk levels (with varying confidence interval sizes), depending on age at exposure, gender, time-frame at-risk and type of cancer considered. This demonstration applies German population data and considers external exposures. Further work is required to comprehensively extend this methodology to internal exposures that are likely to be important in the early stages of a nuclear accident. A discussion is provided here on the potential for such risk-based information to be used by decision makers, in the urgent and transition phases of nuclear emergencies, to identify protective measures (e.g., sheltering, evacuation) in a differential way (i.e., for particularly susceptible sub-groups of a population).


Assuntos
Emergências , Proteção Radiológica/métodos , Humanos , Agências Internacionais , Doses de Radiação , Monitoramento de Radiação , Fatores de Risco
4.
Radiat Prot Dosimetry ; 178(4): 382-404, 2018 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-28981844

RESUMO

Biological and physical retrospective dosimetry are recognised as key techniques to provide individual estimates of dose following unplanned exposures to ionising radiation. Whilst there has been a relatively large amount of recent development in the biological and physical procedures, development of statistical analysis techniques has failed to keep pace. The aim of this paper is to review the current state of the art in uncertainty analysis techniques across the 'EURADOS Working Group 10-Retrospective dosimetry' members, to give concrete examples of implementation of the techniques recommended in the international standards, and to further promote the use of Monte Carlo techniques to support characterisation of uncertainties. It is concluded that sufficient techniques are available and in use by most laboratories for acute, whole body exposures to highly penetrating radiation, but further work will be required to ensure that statistical analysis is always wholly sufficient for the more complex exposure scenarios.


Assuntos
Doses de Radiação , Radiometria/métodos , Incerteza , Carga Corporal (Radioterapia) , Europa (Continente) , Humanos , Monitoramento de Radiação , Radiação Ionizante , Medição de Risco/métodos
5.
Int J Radiat Biol ; 93(1): 127-135, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27572921

RESUMO

PURPOSE: Reliable dose estimation is an important factor in appropriate dosimetric triage categorization of exposed individuals to support radiation emergency response. MATERIALS AND METHODS: Following work done under the EU FP7 MULTIBIODOSE and RENEB projects, formal methods for defining uncertainties on biological dose estimates are compared using simulated and real data from recent exercises. RESULTS: The results demonstrate that a Bayesian method of uncertainty assessment is the most appropriate, even in the absence of detailed prior information. The relative accuracy and relevance of techniques for calculating uncertainty and combining assay results to produce single dose and uncertainty estimates is further discussed. CONCLUSIONS: Finally, it is demonstrated that whatever uncertainty estimation method is employed, ignoring the uncertainty on fast dose assessments can have an important impact on rapid biodosimetric categorization.


Assuntos
Algoritmos , Bioensaio/métodos , Exposição à Radiação/análise , Monitoramento de Radiação/métodos , Triagem/métodos , Teorema de Bayes , Europa (Continente) , Humanos , Guias de Prática Clínica como Assunto , Doses de Radiação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
6.
Health Phys ; 109(6): 582-600, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26509626

RESUMO

Groups of Japanese and American scientists, supported by international collaborators, have worked for many years to ensure the accuracy of the radiation dosimetry used in studies of health effects in the Japanese atomic bomb survivors. Reliable dosimetric models and systems are especially critical to epidemiologic studies of this population because of their importance in the development of worldwide radiation protection standards. While dosimetry systems, such as Dosimetry System 1986 (DS86) and Dosimetry System 2002 (DS02), have improved, the research groups that developed them were unable to propose or confirm an additional contribution by residual radiation to the survivor's total body dose. In recognition of the need for an up-to-date review of residual radiation exposures in Hiroshima and Nagasaki, a half-day technical session was held for reports on newer studies at the 59 th Annual HPS Meeting in 2014 in Baltimore, MD. A day-and-a-half workshop was also held to provide time for detailed discussion of the newer studies and to evaluate their potential use in clarifying the residual radiation exposure to atomic bomb survivors at Hiroshima and Nagasaki. The process also involved a re-examination of very early surveys of radioisotope emissions from ground surfaces at Hiroshima and Nagasaki and early reports of health effects. New insights were reported on the potential contribution to residual radiation from neutron-activated radionuclides in the airburst's dust stem and pedestal and in unlofted soil, as well as from fission products and weapon debris from the nuclear cloud. However, disparate views remain concerning the actual residual radiation doses received by the atomic bomb survivors at different distances from the hypocenter. The workshop discussion indicated that measurements made using thermal luminescence and optically stimulated luminescence, like earlier measurements, especially in very thin layers of the samples, could be expanded to detect possible radiation exposures to beta particles and to determine their significance plus the extent of the various residual radiation areas at Hiroshima and Nagasaki. Other suggestions for future residual radiation studies are included in this workshop report.


Assuntos
Guerra Nuclear , Armas Nucleares , Exposição à Radiação , Partículas beta , Raios gama , Humanos , Japão/epidemiologia , Medições Luminescentes , Exposição à Radiação/estatística & dados numéricos , Monitoramento de Radiação , Radiometria/métodos , Solo , Sobreviventes/estatística & dados numéricos
7.
Radiat Prot Dosimetry ; 164(1-2): 165-9, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25274532

RESUMO

In the event of a large-scale radiological emergency, the triage of individuals according to their degree of exposure forms an important initial step of the accident management. Although clinical signs and symptoms of a serious exposure may be used for radiological triage, they are not necessarily radiation specific and can lead to a false diagnosis. Biodosimetry is a method based on the analysis of radiation-induced changes in cells of the human body or in portable electronic devices and enables the unequivocal identification of exposed people who should receive medical treatment. The MULTIBIODOSE (MBD) consortium developed and validated several biodosimetric assays and adapted and tested them as tools for biological dose assessment in a mass-casualty event. Different biodosimetric assays were validated against the 'gold standard' of biological dosimetry-the dicentric assay. The assays were harmonised in such a way that, in an emergency situation, they can be run in parallel in a network of European laboratories. The aim of this guidance is to give a concise overview of the developed biodosimetric tools as well as how and when they can be used in an emergency situation.


Assuntos
Bioensaio/normas , Exposição à Radiação/análise , Lesões por Radiação/diagnóstico , Monitoramento de Radiação/normas , Liberação Nociva de Radioativos , Triagem/métodos , Emergências , Europa (Continente) , Guias como Assunto , Humanos , Doses de Radiação , Lesões por Radiação/prevenção & controle
8.
Health Phys ; 107(1): 83-9, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24849907

RESUMO

In this note, the authors describe the MULTIBIODOSE software, which has been created as part of the MULTIBIODOSE project. The software enables doses estimated by networks of laboratories, using up to five retrospective (biological and physical) assays, to be combined to give a single estimate of triage category for each individual potentially exposed to ionizing radiation in a large scale radiation accident or incident. The MULTIBIODOSE software has been created in Java. The usage of the software is based on the MULTIBIODOSE Guidance: the program creates a link to a single SQLite database for each incident, and the database is administered by the lead laboratory. The software has been tested with Java runtime environment 6 and 7 on a number of different Windows, Mac, and Linux systems, using data from a recent intercomparison exercise. The Java program MULTIBIODOSE_1.0.jar is freely available to download from http://www.multibiodose.eu/software or by contacting the software administrator: MULTIBIODOSE-software@gmx.com.


Assuntos
Doses de Radiação , Software , Triagem , Humanos , Estudos Retrospectivos
9.
Ann Ist Super Sanita ; 45(3): 297-306, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19861735

RESUMO

The increasing risk of a mass casualty scenario following a large scale radiological accident or attack necessitates the development of appropriate dosimetric tools for emergency response. Luminescence dosimetry has been reliably applied for dose reconstruction in contaminated settlements for several decades and recent research into new materials carried close to the human body opens the possibility of estimating individual doses for accident and emergency dosimetry using the same technique. This paper reviews the luminescence research into materials useful for accident dosimetry and applications in retrospective dosimetry. The properties of the materials are critically discussed with regard to the requirements for population triage. It is concluded that electronic components found within portable electronic devices, such as e.g. mobile phones, are at present the most promising material to function as a fortuitous dosimeter in an emergency response.


Assuntos
Medicina de Emergência/métodos , Luminescência , Efeitos da Radiação , Liberação Nociva de Radioativos , Radiometria/métodos , Humanos , Triagem
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