[Longitudinal Cohort Study of the Relationship between Sleep Duration and Depressive Symptoms in Older People in China].

OBJECTIVE: To investigate the relationship between sleep duration and depressive symptoms in older people in China, and to explore whether there are gender differences in the relationship. METHODS: Accessing the data from China Health and Retirement Longitudinal Study (CHARLS) for 2015 and 2018, we covered in the study a total of 2898 respondents, including 1684 males (58.1%) and 1214 females (41.9%). The 10-item form of Center for Epidemiological Studies Depression Scale (CES-D) was used to measure the depressive symptoms of the older people. The effects of sleep duration on depressive symptoms of older people in China were analyzed with the logistic model. Based on the depressive and non-depressive subgroups in 2018, the differences of health factor variables and sleep duration between 2015 and 2018 were studied. Adjustments were made for health factors presenting statistical differences in 2018 to further explore the stability of the analysis results. RESULTS: Among the female older people, those with short sleep duration and those with long sleep duration had increased risks of developing depressive symptoms [odds ratio ( OR)=1.815, 95% confidence interval ( CI): 1.357-2.429 and OR=1.364, 95% CI: 1.001-1.854, respectively] in comparison to those with normal sleep duration. Among the male older people, no connection was identified between sleep duration and risks for depressive symptoms ( P>0.05). Residing in rural areas, suffering from chronic diseases and having limited ability for Instrumental Activities of Daily Living (IADL) were risk factors for developing depressive symptoms ( P<0.05). The sleep duration for 2015 and that for 2018 were found to be statistically different in the depressive older people ( P<0.001), but no no statistically significant difference was found between the sleep duration for 2015 and that for 2018 among the non-depressive older people. Findings for chronic diseases and IADL for 2015 and those for 2018 were statistically different in the depressive older population ( P<0.001). In the non-depressive older population, findings for chronic diseases, IADL and tobacco smoking status for 2015 and those for 2018 showed statistical difference ( P<0.05). Further sensitivity analysis showed that in the female older population, short sleep duration increased the risks for depressive symptoms ( OR=1.819, 95% CI: 1.356-2.440, P<0.001), while long sleep duration did not affect the risks for depressive symptoms. In the male older population, short or long sleep duration were not associated with the risks for depressive symptoms. CONCLUSION: The association between sleep duration and the risks for depressive symptoms was different for men and women. For the female older population, the possibility of depressive symptoms should be considered for those with short or long sleep duration. For the male older population, short or long sleep duration had little impact on the risks for depressive symptoms.

[Prevalence and Metabolic Abnormalities of Fatty Liver Disease among Adults in Mianyang City,Sichuan Province].

Objective To understand the prevalence and metabolic abnormalities of fatty liver disease among adults in Mianyang City,Sichuan Province,and to analyze their influencing factors.Methods Totally 294 603 adults aged 18 years and older were enrolled by using a multi-stage stratified random sampling method in Mianyang City from November 1,2014 to September 30,2015.Fatty liver was diagnosed by abdominal ultrasound.The general demographic characteristics,smoking history,drinking history,and history of chronic disease were collected through questionnaires.Meanwhile,10 217 subjects were randomly selected for biochemical tests[fasting plasma gluose(FPG),triacylglycerol(TG),total cholesterol(TC),and alanine aminotransferase(ALT)].Results Of these 294 603 subjects,17 105(5.81%)had fatty liver.After having been age-adjusted based on the results of the sixth national census in 2010,the standardized prevalence was 5.32%.The prevalence was significantly higher in males(6.76%;standardized prevalence:7.24%)than in females(5.09%;standardized prevalence:4.08%)(χ 2=365.814,P<0.001)。The prevalence of fatty liver disease was significantly higher in people with current smokers(8.52%)/ex-smokers(8.89%),occasional alcohol users(6.79%)/regular alcohol users(10.51%)/daily alcohol users(10.62%),and patients with hypertension(12.14%)/diabetes(15.19%)/coronary heart disease(10.22%)than those without corresponding characteristics(all P<0.001).Abnormal increase in body mass index,diastolic blood pressure,FPG,TG,TC,and ALT were risk factors for fatty liver in Logistic regression model.Conclusions The prevalence of fatty liver in adults is relatively low in Mianyang City.Patients with fatty liver usually have varying degrees of abnormal increase in blood lipids,blood glucose,blood pressure,and ALT.Healthy lifestyles and comprehensively assessment of metabolic status are conducive to the prevention and treatment of fatty liver and extrahepatic complications.