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Front Bioeng Biotechnol ; 10: 902312, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35646877

RESUMO

Using photothermal therapy to treat cancer has become an effective method, and the design of photothermal agents determines their performance. However, due to the major radiative recombination of a photogenerated electron in photothermal materials, the photothermal performance is weak which hinders their applications. In order to solve this issue, preventing radiative recombination and accelerating nonradiative recombination, which can generate heat, has been proved as a reasonable way. We demonstrated a Cu2MoS4@MXene nanocomposite with an obviously enhanced photothermal conversion efficiency (η = 87.98%), and this improvement can be attributed to the electron migration. Then, a mechanism is proposed based on the electron transfer regulatory effect and the localized surface plasmon resonance effect, which synergistically promote nonradiative recombination and generate more heat. Overall, our design strategy shows a way to improve the photothermal performance of Cu2MoS4, and this method can be extended to other photothermal agents to let them be more efficient in treating cancer.

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