RESUMO
A non-comparative retrospective case-series study was performed on 6 patients (12 eyes) with a confirmed diagnosis of ocular cicatricial pemphigoid (OCP), treated with MicroPulse Transscleral Laser Therapy (MP-TLT), between January 2018 and 2020, with a minimum follow-up of 2 years, in a private ophthalmology practice with offices in Argentina and Colombia. Mean age was 75±6.3 years (66-83 yrs). The severity of ocular cicatricial pemphigoid remained stable 2 years after MP-TLT. Baseline mean IOP was 19.5±5.9 mmHg (13-30 mmHg) and, 24 months after treatment, IOP decreased to a mean of 13.9±1.9 mmHg (10-18 mmHg). The mean IOP reduction was 25.1% ( P : 0.002). The mean number of anti-glaucomatous drugs at baseline was 3.1±0.7, decreasing to 0.6±0.7, 2 years after MP-TLT ( P <0.001). MP-TLT may be considered as a non-incisional approach to glaucoma care for patients with ocular surface diseases, prospective long term studies are needed.
Assuntos
Glaucoma , Terapia a Laser , Penfigoide Mucomembranoso Benigno , Humanos , Idoso , Idoso de 80 Anos ou mais , Pressão Intraocular , Penfigoide Mucomembranoso Benigno/diagnóstico , Estudos Retrospectivos , Estudos Prospectivos , Resultado do Tratamento , Seguimentos , Fotocoagulação a Laser , Corpo Ciliar , Glaucoma/cirurgiaRESUMO
PURPOSE: To evaluate the efficacy of micropulse transscleral cyclophotocoagulation (MP-TSCPC) considering different characteristics: glaucoma subtypes and lens status. METHODS: A retrospective case-series study was designed to evaluate intraocular pressure (IOP), and the number of IOP-lowering medications, used by glaucoma patients treated with MP-TSCPC between 2016 and 2019. Cases had a follow-up period of 12 months. Achieving an IOP reduction higher than 20%, or the decrease of at least one IOP-lowering medication, was considered a successful outcome. The same population was analyzed by classifying them in two groups as: glaucoma subtypes and lens status. The baseline spherical equivalent (SE) was also calculated for considering association with the achieved IOP. RESULTS: A total of 86 eyes were included. In most cases, IOP and IOP-lowering medications were decreased with a statistically significant difference (p < 0.0001), and all of them had a successful outcome. The percentage of IOP drop oscillated between 25.9% (open-angle glaucoma sub-group) and 37.5% (pseudoexfoliative glaucoma sub-group), 12 months after surgery. The difference between the groups was not statistically significant (p 0.20 and 0.32 for glaucoma subtypes and lens status, respectively). The Pearson's coefficient obtained was low for the SE and IOP association, at the 12 -month postoperative mark (- 0.009; p < 0.001). CONCLUSIONS: The MP-TSCPC treatment was successful in decreasing IOP and IOP-lowering medications, in different glaucoma subtypes. Differences between groups (glaucoma subtypes, phakic and pseudophakic eyes) were not statistically significant. No association was found between the SE and the IOP achieved value after MS-TSCPC treatment.
Assuntos
Glaucoma de Ângulo Aberto , Glaucoma , Erros de Refração , Humanos , Glaucoma de Ângulo Aberto/cirurgia , Glaucoma de Ângulo Aberto/etiologia , Estudos Retrospectivos , Lasers Semicondutores/uso terapêutico , Resultado do Tratamento , Fotocoagulação a Laser , Acuidade Visual , Glaucoma/cirurgia , Glaucoma/etiologia , Pressão Intraocular , Erros de Refração/etiologia , Corpo Ciliar/cirurgiaRESUMO
Se ha realizado una búsqueda bibliográfica de todos los estudios biométricos normales y patológicos de 0 a 14 años publicados hasta la fecha, para evaluar y correlacionar los resultados entre los pacientes normales y los portadores de Glaucoma Congénito. Pudiéndose demostrar las diferentes respuestas de estas ante condiciones patológicas y cuáles son los cambios observados de mayor significado clínico