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ABSTRACT: Endometriosis is a chronic inflammatory estrogen-dependent benign disease. It is defined as the endometrium growing outside the uterine cavity and the myometrium. It usually has low FDG uptake but rarely occurs in the ureters. We reported a case of a 47-year-old woman's left ureteral nodule originally misdiagnosed as a ureteral malignant tumor by PET/CT and finally pathologically confirmed as endometriosis.
Assuntos
Endometriose , Ureter , Neoplasias Ureterais , Feminino , Humanos , Pessoa de Meia-Idade , Ureter/diagnóstico por imagem , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Endometriose/diagnóstico por imagem , Endometriose/patologia , Neoplasias Ureterais/diagnóstico por imagem , Erros de DiagnósticoRESUMO
OBJECTIVES: Cerebral venous sinus thrombosis (CVST) can cause sinus obstruction and stenosis, with potentially fatal consequences. High-resolution magnetic resonance imaging (HRMRI) can diagnose CVST qualitatively, although quantitative screening methods are lacking for patients refractory to anticoagulation therapy and who may benefit from endovascular treatment (EVT). Thus, in this study, we used radiomic features (RFs) extracted from HRMRI to build machine learning models to predict response to drug therapy and determine the appropriateness of EVT. MATERIALS AND METHODS: RFs were extracted from three-dimensional T1-weighted motion-sensitized driven equilibrium (MSDE), T2-weighted MSDE, T1-contrast, and T1-contrast MSDE sequences to build radiomic signatures and support vector machine (SVM) models for predicting the efficacy of standard drug therapy and the necessity of EVT. RESULTS: We retrospectively included 53 patients with CVST in a prospective cohort study, among whom 14 underwent EVT after standard drug therapy failed. Thirteen RFs were selected to construct the RF signature and CVST-SVM models. In the validation dataset, the sensitivity, specificity, and area under the curve performance for the RF signature model were 0.833, 0.937, and 0.977, respectively. The radiomic score was correlated with days from symptom onset, history of dyslipidemia, smoking, fibrin degradation product, and D-dimer levels. The sensitivity, specificity, and area under the curve for the CVST-SVM model in the validation set were 0.917, 0.969, and 0.992, respectively. CONCLUSIONS: The CVST-SVM model trained with RFs extracted from HRMRI outperformed the RF signature model and could aid physicians in predicting patient responses to drug treatment and identifying those who may require EVT.
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Trigeminal neuralgia is a common disease in Chinese people. Minimal invasive transforaminal pathway is widely used in treating trigeminal neuralgia. The Hartel pathway is the most commonly used operation route, but it has potential to injure vessels such as arteria meningea media and the internal carotid artery. We measured the location of operation route, foramen spinosum, and foramen lacerum in a three-dimensional pattern. We found that to protect those 2 vessels, the angle and depth of puncture should be well regulated. The horizontal component of the angle between the needle axis and y axis should be more than 22 degrees in women and 20 degrees in men to avoid the injury of arteria meningea media. And for protecting the internal carotid artery, the depth of puncture should be less than 85 mm for women and 93 mm for men, or less than 9 mm after penetrating the meninges.
Assuntos
Procedimentos Cirúrgicos Minimamente Invasivos , Crânio/anatomia & histologia , Neuralgia do Trigêmeo , Adulto , Artéria Carótida Interna/diagnóstico por imagem , Feminino , Humanos , Imageamento Tridimensional , Masculino , Artérias Meníngeas/diagnóstico por imagem , Pessoa de Meia-Idade , Agulhas , Punções/métodos , Fatores Sexuais , Crânio/cirurgia , Tomografia Computadorizada por Raios X , Neuralgia do Trigêmeo/diagnóstico por imagem , Neuralgia do Trigêmeo/cirurgia , Adulto JovemRESUMO
Azo-hydrazone and cis-trans tautomerisms have been firstly observed between two disperse yellow dyes (cis/trans-HL(1) and cis-HL(2)) and three neutral dye-metal complexes (one mononuclear Ni(II) complex 3 and two Cu(II) coordination polymers 4 and 5 formulated as [Ni(trans-L(1))(2)(CH(3)OH)(2)].2H(2)O, [Cu(cis-L(1))(2)](n) and [Cu(L(3))(H(2)O)](n)).