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Vet Dermatol ; 16(2): 87-93, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15842538

RESUMO

Acral mutilation and analgesia (AMA) is reported in 13 French spaniels in Canada. This newly recognized disorder shares striking similarities in clinical features and biopsy findings to the other acral mutilation syndromes or hereditary sensory neuropathies reported in German short-haired pointer dogs, English pointer dogs and English springer spaniels. Clinical signs are first noted between 3.5 and 12 months of age. Affected dogs lick, bite and severely self-mutilate their distal extremities resulting in ulcers with secondary bacterial infection. Auto-amputation of claws, digits and footpads occurs in severe cases. Single or multiple feet can be affected. Affected dogs walked on their severely mutilated feet without evidence of pain, lameness, or ataxia. The majority of the dogs were euthanized within days to months of diagnosis.


Assuntos
Doenças do Cão/genética , Doenças do Cão/patologia , Neuropatias Hereditárias Sensoriais e Autônomas/veterinária , Animais , Cruzamento , Cães , Evolução Fatal , Feminino , Pé/patologia , Neuropatias Hereditárias Sensoriais e Autônomas/genética , Neuropatias Hereditárias Sensoriais e Autônomas/patologia , Masculino , Quebeque , Automutilação
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