Leiomyomatous Hamartoma of Incisive Papilla with High Frenal Attachment: A Case Report.

Aim: This case report aims to describe a rare congenital lesion of the incisive papilla with a high labial frenulum attachment, clinically mimicking congenital epulis but histopathologically diagnosed as an oral leiomyomatous hamartoma. Background: Oral leiomyomatous hamartoma is a very rare congenital lesion, mainly appearing on the median anterior maxilla/incisive papilla and tongue. Case description: This clinical paper is about a rare lesion in a 6-year-old female child whose parents reported to the department with the complaint of slow-growing soft tissue overgrowth between the front teeth of the upper jaw, present since birth. The soft tissue growth is now causing difficulty in biting food and is visible during smiling and speaking, causing an esthetically unpleasing appearance. The clinical examination also revealed a high labial frenulum attached to the lesion. The lesion was provisionally diagnosed as congenital epulis based on the clinical picture. However, after excisional biopsy and histologic evaluation with special stains, the lesion was finally diagnosed as leiomyomatous hamartoma. Conclusion: Surgical excision of the lesion followed by frenectomy was performed with no postoperative complications. Clinical significance: Owing to the rare occurrence and nature of mimicking congenital epulis, it is important for a dental practitioner to have knowledge about these types of lesions. The final diagnosis of such lesions can only be made after histopathological evaluation using special stains. This case report describes the clinical and histopathological features of a rare leiomyomatous hamartoma of the incisive papilla, along with high frenulum attachment and its management. How to cite this article: Pal SS, Khan SA, Navit S, et al. Leiomyomatous Hamartoma of Incisive Papilla with High Frenal Attachment: A Case Report. Int J Clin Pediatr Dent 2024;17(6):717-722.

Peripheral Giant Cell Granuloma - A Case Report of a 9-Year-Old Male Child.

"Giant cell epulis" nowadays known as "peripheral giant cell granuloma" (PGCG) is a soft tissue benign overgrowth seen in the oral cavity. It is a type of reactive exophytic lesion of gingiva whose etiology is still not specific. Peripheral giant cell lesion may not be a life-threatening condition but when the size of the lesion exceeds a certain limit it hampers day-to-day activity of the oral cavity. It may also have a psychological effect on the person. We report a case of a 9-year-old boy with a large peripheral giant cell lesion, which interfered with his chewing habits. The purpose of reporting this case is to create awareness about peripheral giant cell lesions and its treatment modality. Under general anesthesia, the soft tissue growth was excised using an electrocautery that was approximately 5.3 cm in length and 2 cm in width. The patient was reviewed on the 7th day (postoperative), followed by 10, 20, and 30 days. After this, the patient was reviewed monthly for 6 months. Healing was successful without any events. Proper history taking is mandatory before coming to a final diagnosis. Various diagnostic aids help in coming to a confirmatory diagnosis. Complete surgical excision and elimination of any irritant factor along with clearing of the base of the lesion is mandatory to avoid recurrence rate and have a complete uneventful healing.

Prosthetic management of an epulis fissuratum with simple conditioning tissue: A case report.

INTRODUCTION AND IMPORTANCE: Epulis fissuratum is an oral hyperplasic lesion related to an overextended and ill-fitting denture. The treatment of this lesion can be conservative or surgical associated to a good prosthetic management. CASE PRESENTATION: The aim of this article is to present a case report about treatment of an epulis fissuratum with simple conditioning tissue, using provisional removable complete dentures. CLINICAL DISCUSSION: The early management of the epulis fissuratum with conditioning tissue, associated to a good oral hygiene and a correct prosthetic rehabilitation provides satisfactory clinical results and avoids surgical treatment. CONCLUSION: Conditioning tissue technique is a useful conservative approach for the treatment of the epulis fissuratum at an early stage.

Congenital epulis of the newborn; A case report.

INTRODUCTION: Congenital epulis, also known as Neumann's tumor, is an uncommon benign tumor of the oral mucosa that occurs in newborns. It is a rare condition, with fewer than 250 reported cases worldwide. The exact cause or underlying mechanism of this tumor is still not well understood. CASE PRESENTATION: We present a three-day-old male neonate who presented with a swelling on the gingiva that had been present since birth. The infant did not encounter any difficulties with feeding or breathing. The patient had a single, round, pink swelling measuring 2 × 2 × 1 cm on the right maxillary alveolar ridge. The swelling was surgically removed under general anesthesia. Microscopic examination revealed large polygonal cells with abundant granular cytoplasm, centrally located nuclei indicating a diagnosis of congenital epulis. CLINICAL DISCUSSION: Clinical manifestation could vary from no symptoms to feeding difficulty and rarely airway obstruction. It usually tends to grow on anterior alveolar ridge of the newborns, more on the maxilla than on the mandible. Confirmation of the diagnosis is by histopathology, which commonly shows proliferation of polygonal round cells with eosinophilic granular cytoplasm and round central nucleus. Congenital epulis can be approached using different management techniques depending on the size, site of the tumor, and presenting symptoms of the newborns. CONCLUSION: Congenital epulis is rare, but it has to be considered as a differential diagnosis for gingival swelling among neonates.

From prenatal diagnosis to surgical treatment: two case reports of congenital granular cell epulis.

Herein, we detail a multidisciplinary approach and sequential treatment for two infants with congenital granular cell epulis (CGCE). Ultrasonic examinations at 34 weeks of gestation revealed prominent oral masses in both fetuses. To devise a carefully considered treatment strategy, a comprehensive multidisciplinary consultation including oral and maxillofacial surgeons, pediatricians, obstetricians, and anesthesiologists was convened. Following cesarean sections, the lesions were successfully removed, measuring approximately 30 × 15 mm and 30 × 20 mm in size, respectively. Immunohistochemical analysis showed that vimentin was positive, S-100 protein was negative, and NSE protein and CD68 protein were negative. These findings underscore the importance of prenatal diagnosis of congenital granular cell epulis for the effective management of these rare benign conditions.

[Fibromatous Epulis: A Clinical Case Report].

A 35-year-old patient presented with a painless, broad-based exophytic lesion in the buccal interdental region between teeth 13 and 14. Despite oral hygiene efforts the lesion persisted for around one year. Radiology excluded bone involvement, and histopathology after excision confirmed a fibromatous epulis, which is characterized by collagen-rich connective tissue. There was no recurrence within one-year follow-up. Surgical removal proved to be efficient.

Modified coronally advanced flap technique in the treatment of fibrous epulis: A case report with 1-year follow-up.

BACKGROUND: Currently, the treatment of epulis is primarily surgical excision, which would greatly affect the aesthetics of patients if happened in the anterior region. It's challenging for clinicians to balance the aesthetic after surgery and less surgical trauma. To overcome this disadvantage, the authors propose the modified coronally advanced flap technique which applies the principles of minimally invasive surgery to provide satisfactory therapeutic results in fibrous epulis. METHODS: We report a case of an 18-year-old female with the chief complaint of a gingival swelling in the right upper anterior region. After the initial periodontal therapy, the modified surgical approach was applied to this patient. Unlike conventional coronally advanced flap technique, an additional incision was made, and the free portion was rotated into the adjacent space to completely cover the trauma, which avoided the use of the second operative zone. RESULTS: The gingiva recovered with normal color, contour, and consistency after surgery, the papilla filled up the proximal space well and was in good harmony with the adjacent papillae. The surgical results remained stable during the follow-up period. CONCLUSIONS: The use of modified coronally advanced flap technique allows the clinician to successfully resume the natural appearance of gingiva in the treatment of fibrous epulis, as well as simplify the surgical approach, shorten the operative time, and demonstrate no tendency of recurrence. KEY POINTS: Why is this case new information? This novel technique not only removes the epulis, but also takes into account the postoperative aesthetics of the surgery at the same time. This minimally invasive surgical technique reduces operative time and increases patient comfort. Keys to successful management of this case are as follows: (i) Adequate preoperative assessment of the location of the additional incision; (ii) tension-free coronal flap advancement. What are the primary limitations to success in this case? Clinical studies with long-term outcomes of this approach are needed. This procedure may be limited to larger gingival tumors.

Manejo cirúrgico da hiperplasia fibrosa: relato de caso / Surgical management of fibrous hyperplasia: case report / Tratamiento quirúrgico de la hiperplasia fibrosa: informe de um caso

Objetivo: Relatar um caso de hiperplasia fibrosa inflamatória em lábio inferior, decorrente de um transtorno de comportamento repetitivo (mordedura) e o seu devido tratamento. Relato de caso: Paciente do gênero masculino, 27 anos de idade, apresentou aumento de volume em região de lábio inferior, indolor, com evolução clínica de seis a sete meses, com relatos de práticas de mordedura em região de lábio inferior. Ao exame clínico observou-se lesão exofítica em coloração de mucosa, pediculada, medindo cerca de 8mm, no seu maior diâmetro, com aspecto circunferencial, consistente à palpação e não sangrante. O paciente foi submetido à biópsia excisional, mantendo-se uma distância mínima de 5mm do pedículo. Conclusão: No caso relato, o paciente foi submetido a uma biópsia excisional com a completa remoção da lesão e obteve um prognóstico favorável... (AU)

Objective: To report a case of inflammatory fibrous hyperplasia in the lower lip, resulting from a repetitive be havior disorder (biting) and its proper treatment. Case report: Male patient, 27 year sold, presented pain less swelling in the lowerl ipregion, with clinical evolution of sixt o seven months, with report sof biting practices in the lower lip region. Clinical examination revealed an exophytic lesion in mucosal color, peduncula ted, mea suring about 8 mm in its largest diameter, with a circumferent ial appearance, consisten ton palpation and not bleeding. The patient underwent excisional biopsy, keeping a minimum distance of 5 mm from the pedicle. Conclusion: In the case report, the patient underwent a nexcision al biopsy with the complete removal of the lesion and obtained a favorable prognosis... (AU)

Objetivo: Informar de un caso de hiperplasia fibrosa inflamatoria del labio inferior debido a um trastorno de comportamiento repetitivo (morder) y su tratamiento. Reporte de caso: Paciente masculino, de 27 años, presentó un aumento de volumen em la región del labio inferior, indoloro, com evolución clínica de seis a siete meses, con reporte de prácticas de mordedura em la región del labio inferior. El examen clínico reveló una lesión exofítica, pedunculada, de coloración mucosa, que medía aproximadamente 8mm em su mayor diámetro, de aspecto circunferencial, consistente a la palpación y no sangrante. El paciente fue sometido a una biopsia excisional, manteniendo una distancia mínima de 5mm del pedículo. Conclusión: Em el caso relatado, el paciente fue sometido a una biopsia excisional com la remoción completa de lalesión y obtuvo um pronóstico favorable... (AU)

Congenital epulis: a rare diagnosis of newborn.

Congenital epulis is a rare benign soft tissue lesion that occurs exclusively in neonates and usually develops from the alveolar mucosa at the frontal region of the maxilla. Lesions may be sessile or pedunculated, normal in color or reddish and vary in size from a few millimeters to a few centimeters. Although spontaneous regression has also been reported, surgical excision is indicated for large tumors that may obstruct the airway and make feeding the child difficult. In this case report, we present a rare case of congenital epulis involving the right side of the maxillary alveolar mucosa in a neonate delivered vaginally at Dhulikhel Hospital, Kavreplanchok, Nepal. The lesion was surgically removed by electrocautery, and histologic examination confirmed the clinical diagnosis of congenital epulis. No complications occurred after surgery, and when the child was examined 6 months later, no evidence of recurrence noticed.

Management of hormonal induced recurrent ulcerative fibrous epulis with osseous metaplasia: A case report.

Key Clinical Message: Understanding the role of hormones in periodontitis is important. Periodontal microscopic surgery approach in the treatment of fibrous epulis is not indicated. Wider flap access with root planning is indicated to control the lesion in one phase. Abstract: We present a case of a 40-year-old female who presented with a gingival hyperplastic lesion around the maxillary left permanent central and lateral incisors. Patient's medical history reveals a recent pregnancy, hypothyroidism, ulcerative colitis, and schizoaffective disorder. All medical conditions were controlled by medications. The lesion was excised using a minimally invasive periodontal surgical technique, and the biopsy results confirmed a diagnosis of ulcerative fibrous epulis with osseous metaplasia. No curettage or local debridement was done under the assumption that the patient's oral hygiene was satisfactory and due to aesthetic concerns of gingival recession and creation of black triangles. The lesion recurred after 3 months and was removed using a traditional more invasive surgical technique. The patient was followed up for 2 years, and there was no further recurrence due to the complete excision of the lesion in the second surgery and the disappearance of the hormonal-related factors post-pregnancy that could have contributed to the gingival hyperplasia. The unique component of the case we are presenting is the comparison between two different surgical techniques and the conduction versus absence of local periodontal debridement after surgical excision as well as the possible correlation between oral supplements and the calcific nature of the lesion(s) reported. The case we present demonstrates that a more invasive traditional surgical approach together with local periodontal therapy provide an optimum treatment outcome in conjunction with elimination of any associated etiological factors. We also propose that hormones are more important as an etiological factor in developing fibrous epulis lesions than medical conditions and medications.

Peripheral giant cell granuloma: a case series and brief review.

We report three varied presentations of peripheral giant cell granuloma and provide an up-to-date summary on the diagnosis, treatment and prognosis of this everyday swelling, including lessons learned.

An aggressive pregnancy epulis with extensive alveolar bone resorption and tooth displacement.

Pregnancy epulis is a common and benign vascular tumor that reaches 5% of pregnant women; it respects adjacent structures, such as bone, teeth, and sinus mucosa. This paper reports a rare case of extensive pregnancy epulis with alveolar bone lysis, tooth displacement, and sinusal floor lysis. A 23-year-old pregnant woman with 23 weeks of amenorrhea was referred to the Department of Oral and Maxillofacial Surgery with a large maxillary mass and spontaneous bleeding, causing difficulty in speaking and swallowing. Due to the rapid development, the stage of pregnancy, and the need for a sure diagnosis of a benign lesion, a surgical excision was performed. After 1 month, the patient recovered from swallowing and speaking. Pregnancy epulis can be locally aggressive and involve alveolar bone. Biopsy allows to confirm the diagnosis. Surgery during pregnancy or birth waiting should be well ponderated in correlation with the size of the tumor and the delay to birth.

Anesthetic management of congenital epulis in a newborn: a case report.

The epulis of the newborn is a granular cell tumor that originates from the mucosa of the gingiva. Case presentation: The authors report a case of a 4-day-old neonate with a large mass arising from the right upper gingival area and occupying most of the oral cavity who presented for surgery with a potentially difficult airway. Intubation was achieved uneventfully using a gaseous induction with an appropriate-size facemask and displacement of the epulis to allow cautious laryngoscopy. Discussion: General anesthesia offers good airway protection and also alleviates the stress and pain associated with the surgery. Conclusion: Congenital epulis is a relatively rare congenital tumor of a newborn, which is one of the causes of difficult airways in neonates and children. However, after slight manipulation of the tumor, endotracheal intubation for the administration of general anesthesia is attainable.

A large-cohort study of 2971 cases of epulis: focusing on risk factors associated with recurrence.

BACKGROUND: To analyze the clinicopathological features of different histological subtypes of epulis, and evaluate the risk factors associated with recurrence. MATERIALS AND METHODS: A retrospective study including 2971 patients was performed. The patients' sex, age, location, size, histological subtypes, recurrence information, oral hygiene habits, periodontitis symptoms and smoking history were retrieved from the patient medical records and follow-up information. RESULTS: Among the 2971 cases, focal fibrous hyperplasia (FFH) was the most common lesion (60.92%), followed by peripheral ossifying fibroma (POF) (29.32%), pyogenic granuloma (PG) (8.08%) and peripheral giant cell granuloma (PGCG) (1.68%). The peak incidence of epulis was in the third and fourth decade of life, with a mean age of 45.55 years. Female predominance was found in all types of lesions with a female to male ratio of 1.71:1. PG had the highest recurrence rate (17.18%), followed by POF (12.98%), FFH (9.55%) and PGCG (8.82%). Histological subtypes were significantly correlated with the recurrence of epulis (P = 0.013). Regular supportive periodontal therapy (P = 0.050) had a negative correlation with recurrence, whereas symptoms of periodontitis (P < 0.001) had a positive correlation with the recurrence of epulis. CONCLUSIONS: Controlling the periodontal inflammation and regular supportive periodontal therapy might help reduce the recurrence of epulis.

Congenital Epulis Diagnosed Antenatally.

Background: Congenital epulis is a benign gingival tumor whose differential diagnosis includes other oral-facial masses such as teratoma, hemangioma, lymphatic malformation and dermoid cysts. This tumor can cause obstruction of the airway or feeding problems in the newborn. Surgical excision is the treatment of choice. Case Report: We present a case of congenital epulis, diagnosed prenatally with ultrasonography. Conclusion: Although difficult, a defined prenatal image of congenital epulis is possible by means of accurate high-resolution ultrasonography. It facilitates the narrowing down of differential diagnosis. The confirmatory final diagnosis relies on histopathological examination.

Giant cell epulis.

Giant cell epulis (peripheral giant cell granuloma) typically appears as a reactive benign lesion in the oral cavity in areas following local irritation or chronic trauma. Here we describe the case of a 45-year-old male patient who presented with the chief complaint of a large gingival mass in the anterolateral maxilla. There had been progressive growth within the past few months, with increased painless discomfort during mastication. The patient also reported bleeding during interdental cleaning. A full physical work-up led to the suspicion of giant cell epulis alongside other differentials including mucosal hemangioma and squamous cell carcinoma, with unremarkable laboratory values. Imaging including computed tomography showed signs of previous insertion of metal implants on either side of the lesion alongside mucosal hyperplasia. A confirmatory biopsy was taken and showed multiple giant cells on a reactive bed of stroma, in line with the diagnosis of giant cell epulis. Oral inflammatory conditions such as giant cell epulis have greater chances of local recurrence and, therefore, careful investigation with timely and accurate diagnosis is imperative for appropriate early treatment. Complete surgical excision should then be employed to prevent relapses, as incomplete removal can lead to further recurrence. Identification and eradication of potential sources of irritation should also be considered when treating the patient, to avoid further recurrence.

Congenital epulis in a newborn.

Congenital epulis (CE) is an extremely rare benign tumor of the gingiva that is found on the alveolar ridge of newborns, and the main treatment option is simple excision. Postoperative prognosis is very good, and spontaneous regression may occur despite incomplete excision. This report presented a rare case of CE and its healing process after surgery under local anesthesia. The treatment plan was decided upon through consultation between a medical team and the patient's family, with surgical excision for the main lesion, which benefitted from surgery, and follow-up for a very small-sized lesion, which was thought to be appropriate for a newborn. No recurrence was found after its removal, and favorable healing was observed.

Épulis congénito

Introducción: El épulis congénito es un tumor benigno muy poco frecuente de etiología desconocida. Se presenta principalmente en la cresta del reborde alveolar, cerca de la región canina. Su tamaño es variable y puede llegar a ocupar toda la cavidad oral. La prevalencia es mayor en el maxilar superior y en el sexo femenino. Objetivo: Examinar la literatura en relación con el diagnóstico y tratamiento del épulis congénito a propósito de la presentación de un caso clínico poco frecuente. Presentación del caso: Paciente femenina, de 5 días de vida, que ingresa con aumento de volumen polilobulado, de 1 cm de diámetro, ubicado en reborde alveolar superior izquierdo, rojizo, de consistencia firme, base pediculada, que ocasionaba dificultades en la alimentación. No se identificaron otras alteraciones. Por la clínica y la naturaleza congénita de la entidad se planteó el diagnóstico de épulis congénito y se realizó la excéresis quirúrgica bajo anestesia general. El diagnóstico histopatológico se correlacionó con los hallazgos clínicos y reveló épulis congénito. Conclusiones: El épulis congénito es un tumor benigno muy poco frecuente. No existe consenso entre los autores en relación con su patogenia e histogénesis. El tratamiento indicado es la excéresis quirúrgica en el momento del nacimiento, principalmente cuando interfiere en la alimentación y la respiración. El diagnóstico precoz y tratamiento oportuno eliminan completamente la lesión y las complicaciones asociadas a este tumor.

Introduction: Congenital epulis is a very rare benign tumor of unknown etiology. It occurs mainly on the crest of the alveolar ridge, near the canine region. Its size is variable and can occupy the entire oral cavity. The prevalence is higher in the upper jaw and in the female sex. Objective: To examine the literature related to the diagnosis and treatment of congenital epulis regarding the presentation of a rare clinical case. Presentation of the case: Female patient, 5 days old, who is admitted with an increase in polylobed volume, 1 cm in diameter, located in the left upper alveolar ridge, reddish, of firm consistency, pediculate base, which caused difficulties in feeding. No other alterations were identified. Due to the clinical and congenital nature of the entity, the diagnosis of congenital epulis was stated and surgical exeresis was performed under general anesthesia. Histopathological diagnosis was correlated with clinical findings and revealed congenital epulis. Conclusions: Congenital epulis is a very rare benign tumor. There is no consensus among the authors regarding its pathogenesis and histogenesis. The indicated treatment is surgical exeresis at the time of birth, mainly when it interferes with feeding and breathing. Early diagnosis and timely treatment completely eliminate the lesion and complications associated with this tumor.

Congenital granular cell epulis: 24 new cases with more differences than similarities to granular cell tumor.

Congenital granular cell epulis (CGCE) is a rare tumor of gingiva that is exclusive to newborns, has marked female predominance, and is rarely associated with other abnormalities. Although benign in behavior, CGCE can be lethal by obstruction of respiration and/or deglutition and can require a multidisciplinary team of specialist at birth for survival of an otherwise normal infant. Histologically, CGCE resembles granular cell tumor (GCT), but unlike GCT, which is Schwannian-derived, derivation of CGCE remains an enigma, largely because of its low prevalence. This study presents 24 new cases of CGCE, the largest series since the original description 150 years ago and permits detailed study of homogeneity of cases diagnosed as CGCE as well as detailed comparisons of CGCE with GCT by clinical, morphological, immunohistochemical, and ultrastructural studies. The data show homogeneity within the CGCE cases, more differences than similarities between CGCE and GCT, and no immunohistochemical staining for common placental proteins/hormones in CGCE. The findings support a primitive mesenchymal cell origin, and a progressive degenerative process in CGCE, rather than neoplasia. Prenatal detection of this lesion is important to facilitate adequate preparations for support of these infants during labor and delivery.