RESUMO
PURPOSE: To investigate lenticule decentration following small incision lenticule extraction (SMILE) via the pupil center or tear film mark centration method and compare induction of corneal higher order aberrations (HOAs) between the two methods. METHODS: This study analyzed decentration values obtained from tangential topography difference maps of 100 eyes (100 patients) undergoing SMILE with the pupil center (n = 50) or tear film mark (n = 50) centration method. Total HOAs and component aberrations were measured preoperatively and 6 months postoperatively. Relationships between the magnitudes of decentration and induced corneal HOAs were assessed. RESULTS: Both vertical and total decentered displacement were significantly different (P < .001) between the two centration groups. A significant relationship between the preoperative pupillary offset and decentration was noted in the pupil center group (P < .001), but not in the tear film mark group (P = .530). Significantly greater induction of total HOAs, coma, and vertical coma (all P < .001), as well as horizontal coma (P = .001) and spherical aberration (P = .023), were observed in the pupil center group. Association between the total decentered displacement and induced total HOAs (P < .001), as well as all other significantly increased phenomena, was also significant in the pupil center group. Differences in decentered displacement and induced corneal HOAs were significant for preoperative pupillary offset (angle kappa) greater than 200 µm, but not for angle kappa less than 200 µm. CONCLUSIONS: SMILE with tear film mark centration can yield improved treatment centration and less induction of total HOAs, coma, and spherical aberrations. [J Refract Surg. 2020;36(4):239-246.].
Assuntos
Substância Própria/cirurgia , Cirurgia da Córnea a Laser/métodos , Topografia da Córnea/métodos , Aberrações de Frente de Onda da Córnea/cirurgia , Lasers de Excimer/uso terapêutico , Pupila , Lágrimas/metabolismo , Adolescente , Adulto , Substância Própria/patologia , Aberrações de Frente de Onda da Córnea/patologia , Aberrações de Frente de Onda da Córnea/fisiopatologia , Feminino , Seguimentos , Humanos , Masculino , Período Pós-Operatório , Refração Ocular , Estudos Retrospectivos , Acuidade Visual , Adulto JovemRESUMO
AIM: To investigate the change in posterior corneal elevations (PCEs) of eyes with extremely high myopia 2 years after small incision lenticule extraction (SMILE). METHODS: We evaluated 39 eyes of 39 patients with spherical equivalent higher than -10.00 dioptres (D). Using a Scheimpflug camera (Pentacam), we measured change in PCEs at 1 day, 3 months, 6 months and 2 years after SMILE. Another 34 eyes of 34 patients who underwent femtosecond laser-assisted in situ keratomileusis (FS-LASIK) were examined before, at 1 day and long-term after surgery as the control group. For each eye, elevations at central, thinnest, maximal points and 24 other predetermined points were measured. RESULTS: No significant forward displacements of PCEs were observed in both surgeries. The maximal but not significant forward displacement occurred around 3-6 months following SMILE, and all returned to original levels 6 months postoperatively except superior area. The peripheral area tended to displace backward, while the central area tended forwardly. In both procedures, elevations along horizontal meridians, inferior and temporal hemispheres were significantly higher than those along vertical meridians, superior and nasal hemispheres, respectively (p<0.05). Elevation on the 4 mm, 6 mm diameters at 1 day and on the 6 mm diameter and temporal hemisphere at long-term follow-up postoperatively were significantly higher in FS-LASIK than SMILE (p<0.05). Change in elevations on the 6 mm diameter circle correlated with residual bed thickness (p=0.047). CONCLUSIONS: SMILE is a safe way to correct for myopia higher than -10 D, with PCEs remaining stable 2 years after surgery.
Assuntos
Córnea/patologia , Cirurgia da Córnea a Laser/métodos , Lasers de Excimer/uso terapêutico , Miopia/cirurgia , Adulto , Substância Própria/cirurgia , Cirurgia da Córnea a Laser/efeitos adversos , Topografia da Córnea , Aberrações de Frente de Onda da Córnea/etiologia , Aberrações de Frente de Onda da Córnea/patologia , Feminino , Seguimentos , Humanos , Ceratocone/etiologia , Ceratocone/patologia , Ceratomileuse Assistida por Excimer Laser In Situ/efeitos adversos , Ceratomileuse Assistida por Excimer Laser In Situ/métodos , Lasers de Excimer/efeitos adversos , Masculino , Pessoa de Meia-Idade , Miopia/patologia , Miopia/fisiopatologia , Complicações Pós-Operatórias , Estudos Prospectivos , Acuidade Visual/fisiologia , Adulto JovemRESUMO
PURPOSE: To evaluate the long-term changes in anterior and posterior corneal irregular astigmatism and curvatures after small incision lenticule extraction (SMILE). METHODS: Fifty eyes of 28 patients underwent SMILE for myopic astigmatism. All procedures were performed using the VisuMax® femtosecond laser. A Scheimpflug camera was used for preoperative and 3-year postoperative tomography. Anterior and posterior corneal Fourier parameters (spherical component, regular astigmatism, asymmetry, and irregularity) and curvature data were evaluated and compared within 2 subgroups according to the magnitude of the refractive correction (low myopia group: spherical equivalent (SEQ) ≥ -6 D; high myopia group: (SEQ) < -6 D). Associations between all studied parameters were examined. RESULTS: Three years postoperatively, an increase in anterior corneal curvatures and Fourier parameters was detected and the results were strongly correlated with the preoperative SEQ, lenticule thickness, and volume. At the posterior cornea, the flattest radius, corneal astigmatism, spherical component, regular astigmatism, and irregularity decreased only in the high myopia group. A correlation was found between changes in posterior astigmatism and changes in anterior radii (R = 0.349, P = 0.014), SEQ (R = 0.396, P = 0.0049), and lenticule thickness (R = -0.414, P = 0.0031). Moreover, changes in posterior corneal irregularity correlated with the changes in anterior and posterior radii (R = -0.3, P = 0.034, and R = 0.449, P = 0.0012, respectively), changes in preoperative SEQ (R = 0.284, P = 0.0477), and lenticule thickness (R = -0.311, P = 0.0298). CONCLUSIONS: Three years after SMILE, there was a reduction of posterior astigmatism in high refractive corrections. This could result in undercorrection in high refractive treatments. Total irregularities increased despite the compensatory effect of the posterior corneal surface.
Assuntos
Astigmatismo/cirurgia , Cirurgia da Córnea a Laser/métodos , Miopia/cirurgia , Procedimentos Cirúrgicos Refrativos/métodos , Adulto , Aberrações de Frente de Onda da Córnea/etiologia , Aberrações de Frente de Onda da Córnea/patologia , Feminino , Seguimentos , Análise de Fourier , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
PURPOSE: To evaluate the corneal topographic changes and postvitrectomy astigmatism after 27-gauge (g) microincision vitrectomy surgery (MIVS) by using Pentacam HR-Scheimpflug imaging system. METHODS: This prospective descriptive study included 30 eyes of 30 patients who underwent 27-g MIVS. All eyes underwent a Pentacam HR examination preoperatively and on the first week, first month and third month postoperatively. The power of the corneal astigmatism, mean keratometry (K m), K 1 and K 2 values and corneal asphericity (Q value) values for the both front and back surfaces of the cornea, index of surface variance (ISV), index of vertical asymmetry (IVA), index of height asymmetry (IHA), index of height decentration (IHD) and higher-order aberrations including coma, trefoil, spherical aberration, higher-order root-mean-square and total RMS were recorded. Additionally, the mean induced astigmatism was estimated by vector analysis. RESULTS: No statistically significant changes were observed in the mean power of corneal astigmatism, mean keratometry, K 1 and K 2 values, corneal asphericity values, ISV, IVA, IHA, IHD and higher-order aberrations on the first week, first month and third month after the operation. The mean surgically induced astigmatism was calculated as 0.23 ± 0.11 D on the first week, 0.19 ± 0.10 D on the first month and 0.19 ± 0.08 D on the third month postoperatively. CONCLUSION: Minor corneal surface and induced astigmatic changes are expected to result in rapid visual rehabilitation after pars plana vitrectomy with the 27-g MIVS system.
Assuntos
Astigmatismo/patologia , Topografia da Córnea , Aberrações de Frente de Onda da Córnea/patologia , Vitrectomia/efeitos adversos , Vitrectomia/métodos , Idoso , Idoso de 80 Anos ou mais , Astigmatismo/etiologia , Aberrações de Frente de Onda da Córnea/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Estudos Prospectivos , Técnicas de SuturaRESUMO
PURPOSE: This study aimed to investigate the effect of iris registration (IR) on visual outcomes in wavefront-guided LASEK for myopic astigmatism. METHODS: The retrospective chart review was performed for wavefront-guided LASEK using VISX Star S4 in patients with myopic astigmatism (cylinder ≥ 1.00 diopter[D]). Eyes were divided into IR group (LASEK with IR at the time of surgery) and Non-IR group (LASEK without IR system + failed-IR engagement during LASEK). Visual acuity (VA), astigmatism, higher-order aberration (HOA), and contrast sensitivity were assessed preoperatively and 3 months postoperatively. The IR and Non-IR groups were subcategorized depending on the spherical equivalent (lower myopia ≤-5.00 D vs. higher myopia >-5.00 D) for the comparison of HOA changes. RESULTS: Postoperative uncorrected VAs showed no differences between IR (n = 30) and Non-IR (n = 46). In astigmatic vector analyses, no differences were noted in the mean magnitude of error and the mean angle of error between two groups. There were no differences in postoperative total HOA, spherical aberration (SA), coma, and trefoil between the groups, either. The total HOA and SA increased in both groups, while coma increased only in Non-IR. In higher myopia, ΔRMS of coma was smaller in IR. Preoperative and postoperative total HOA were linearly correlated in Non-IR, but not for IR. Contrast sensitivity of 12 cycles per degree improved in both groups. CONCLUSION: IR had similar outcomes to conventional trackers in wavefront-guided LASEK, with less tendency of inducing coma, especially in higher myopia.
Assuntos
Astigmatismo/cirurgia , Ceratectomia Subepitelial Assistida por Laser/métodos , Miopia/cirurgia , Adolescente , Adulto , Astigmatismo/fisiopatologia , Sensibilidades de Contraste/fisiologia , Aberrações de Frente de Onda da Córnea/patologia , Feminino , Humanos , Masculino , Miopia/fisiopatologia , Estudos Retrospectivos , Acuidade Visual/fisiologia , Adulto JovemRESUMO
PURPOSE: To analyze the changes in anterior and posterior corneal surfaces and aberrations in patients who underwent intracorneal ring segment (ICRS) implantation for the treatment of keratoconus. METHODS: Eighty-nine eyes of 59 patients with keratoconus who underwent ICRS implantation were analyzed. All eyes were evaluated using a tomography system combining a Placido disc and Scheimpflug photography before and at least 6 months after surgery. Total, anterior, and posterior corneal aberrations, anterior and posterior sagittal and tangential anterior and posterior curve analysis, keratometry (K), minimum corneal thickness, and anterior chamber depth were analyzed before and after surgery. RESULTS: Flattening with a decrease in the cone shape on the anterior corneal surface and steepening in the paracentral area with persistence of cone appearance on the posterior corneal surface were noted in all cases after ICRS implantation. The total corneal higher-order aberrations (HOAs) significantly decreased from 1.09 ± 0.43 to 0.71 ± 0.32 µm, and anterior corneal HOAs significantly decreased from 0.98 ± 0.46 to 0.81 ± 0.37 µm, whereas the posterior corneal HOAs increased from 0.53 ± 0.29 to 0.66 ± 0.25 µm after ICRS implantation (P < 0.05). There was a significant decrease in anterior maximum keratometry, but there was a significant increase in posterior maximum keratometry after ICRS implantation (P < 0.05). CONCLUSIONS: The cone shape persists on the posterior corneal surface despite its correction on the anterior corneal surface, leading to a decrease in anterior corneal aberrations and an increase in posterior corneal aberrations after ICRS implantation in eyes with keratoconus.
Assuntos
Córnea/patologia , Substância Própria/cirurgia , Aberrações de Frente de Onda da Córnea/patologia , Ceratocone/cirurgia , Próteses e Implantes , Implantação de Prótese , Adolescente , Adulto , Câmara Anterior/patologia , Córnea/cirurgia , Topografia da Córnea , Feminino , Humanos , Ceratocone/patologia , Masculino , Pessoa de Meia-Idade , Refração Ocular , Acuidade Visual , Adulto JovemRESUMO
PURPOSE: To study the effect on vision of induced negative and positive spherical aberration within the range of laser vision correction procedures. METHODS: In 10 eyes (mean age: 35.8 years) under cyclopegic conditions, spherical aberration values from -0.75 to +0.75 µm in 0.25-µm steps were induced by an adaptive optics system. Astigmatism and spherical refraction were corrected, whereas the other natural aberrations remained untouched. Visual acuity, depth of focus defined as the interval of vision for which the target was still perceived acceptable, contrast sensitivity, and change in spherical refraction associated with the variation in pupil diameter from 6 to 2.5 mm were measured. RESULTS: A refractive change of 1.60 D/µm of induced spherical aberration was obtained. Emmetropic eyes became myopic when positive spherical aberration was induced and hyperopic when negative spherical aberration was induced (R2 = 81%). There were weak correlations between spherical aberration and visual acuity or depth of focus (R2 = 2% and 3%, respectively). Contrast sensitivity worsened with the increment of spherical aberration (R2 = 59%). When pupil size decreased, emmetropic eyes became hyperopic when preexisting spherical aberration was positive and myopic when spherical aberration was negative, with an average refractive change of 0.60 D/µm of spherical aberration (R2 = 54%). CONCLUSIONS: An inverse linear correlation exists between the refractive state of the eye and spherical aberration induced within the range of laser vision correction. Small values of spherical aberration do not worsen visual acuity or depth of focus, but positive spherical aberration may induce night myopia. In addition, the changes in spherical refraction when the pupil constricts may worsen near vision when positive spherical aberration is induced or improve it when spherical aberration is negative. [J Refract Surg. 2017;33(7):470-474.].
Assuntos
Sensibilidades de Contraste/fisiologia , Córnea/patologia , Aberrações de Frente de Onda da Córnea/cirurgia , Ceratomileuse Assistida por Excimer Laser In Situ/métodos , Lasers de Excimer/uso terapêutico , Óptica e Fotônica , Refração Ocular/fisiologia , Adulto , Aberrações de Frente de Onda da Córnea/patologia , Aberrações de Frente de Onda da Córnea/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
PURPOSE: To comparatively investigate changes in epithelial thickness between myopic femtosecond laser-assisted LASIK (FS-LASIK) and small incision lenticule extraction (SMILE). METHODS: This study compared the topographic epithelial thickness changes in 175 myopic eyes undergoing FS-LASIK (62 eyes) or SMILE (113 eyes). Epithelial thickness was obtained using spectral-domain optical coherence tomography before surgery and 1 and 3 months after surgery. Topographic epithelial thickness obtained by automatic algorithm and thickness variability (standard deviation over 17 imaged areas) was compared between two groups. Postoperative epithelial thickness changes were correlated with treatment parameters. RESULTS: For FS-LASIK, the mean epithelial thickness of the center zone (2 mm in diameter), paracenter (2 to 5 mm), and mid-periphery (5 to 6 mm) increased by 3.4, 4.3, and 2.1 µm, respectively, at 1 month and by 4.4, 5.1, and 2.9 µm, respectively, at 3 months. There was an increase of 2.5, 3.9, and 4.5 µm, respectively, at 1 month and 3.0, 4.2, and 4.9 µm, respectively, at 3 months following SMILE. The epithelial thickness did not change between 1 and 3 months postoperatively following SMILE, whereas it increased further after FS-LASIK. A larger increase of epithelial thickness was observed in the central zone at 3 months following FS-LASIK than SMILE, whereas the opposite was observed in the mid-periphery. The topographic thickness variability was greater after FS-LASIK than SMILE. Corneal epithelial thickening was proportional to the amount of myopia correction after both procedures. CONCLUSIONS: Topographic epithelial remodeling patterns differ following FS-LASIK or SMILE. Epithelial remodeling appears to stabilize more rapidly following SMILE than FS-LASIK. [J Refract Surg. 2017;33(4):250-256.].
Assuntos
Substância Própria/cirurgia , Cirurgia da Córnea a Laser/métodos , Topografia da Córnea/métodos , Epitélio Corneano/patologia , Ceratomileuse Assistida por Excimer Laser In Situ/métodos , Lasers de Excimer/uso terapêutico , Miopia/cirurgia , Adulto , Substância Própria/patologia , Aberrações de Frente de Onda da Córnea/patologia , Aberrações de Frente de Onda da Córnea/fisiopatologia , Aberrações de Frente de Onda da Córnea/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Miopia/patologia , Miopia/fisiopatologia , Período Pós-Operatório , Estudos Prospectivos , Tomografia de Coerência Óptica , Resultado do Tratamento , Acuidade Visual , Adulto JovemRESUMO
OBJECTIVES: To investigate the corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE) and compare the results using femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and femtosecond laser lenticule extraction (FLEx). METHODS: This study included 160 eyes in total; 73 eyes underwent SMILE, 52 eyes underwent FS-LASIK, and 35 eyes underwent FLEx surgery. Corneal HOAs of the anterior surface, posterior surface, and total cornea were evaluated using a Scheimpflug camera over 6-mm diameter preoperatively and 3 months postoperatively. RESULTS: The anterior and total corneal HOAs significantly increased after SMILE, FS-LASIK, and FLEx surgeries, especially the spherical aberration and coma, whereas most posterior corneal HOAs remained unchanged. The SMILE procedure induced significantly lower anterior corneal and total corneal spherical aberration and third to eighth HOAs compared with FLEx surgery (P<0.01). FLEx surgery induced higher posterior corneal coma than SMILE (P=0.013) and FS-LASIK (P<0.001) surgeries. CONCLUSIONS: SMILE, FS-LASIK, and FLEx surgeries mainly induced coma and spherical aberrations in the anterior surface and total cornea. The SMILE procedure induced less spherical aberration of the anterior cornea and total cornea than FLEx surgery. The posterior corneal spherical aberration significantly increased after FS-LASIK surgery. The SMILE procedure seems to have fewer effects on posterior corneal coma compared with the FLEx procedure.
Assuntos
Cirurgia da Córnea a Laser/métodos , Aberrações de Frente de Onda da Córnea/patologia , Lasers de Excimer/uso terapêutico , Miopia/cirurgia , Adulto , Aberrações de Frente de Onda da Córnea/etiologia , Feminino , Humanos , Ceratomileuse Assistida por Excimer Laser In Situ/métodos , Masculino , Estudos Retrospectivos , Adulto JovemRESUMO
PURPOSE: To evaluate changes in anterior corneal topography and higher-order aberrations (HOA) after 14-days of rigid gas-permeable (RGP) contact lens (CL) wear in keratoconus subjects comparing two different fitting approaches. METHODS: Thirty-one keratoconus subjects (50 eyes) without previous history of CL wear were recruited for the study. Subjects were randomly fitted to either an apical-touch or three-point-touch fitting approach. The lens' back optic zone radius (BOZR) was 0.4mm and 0.1mm flatter than the first definite apical clearance lens, respectively. Differences between the baseline and post-CL wear for steepest, flattest and average corneal power (ACP) readings, central corneal astigmatism (CCA), maximum tangential curvature (KTag), anterior corneal surface asphericity, anterior corneal surface HOA and thinnest corneal thickness measured with Pentacam were compared. RESULTS: A statistically significant flattening was found over time on the flattest and steepest simulated keratometry and ACP in apical-touch group (all p<0.01). A statistically significant reduction in KTag was found in both groups after contact lens wear (all p<0.05). Significant reduction was found over time in CCA (p=0.001) and anterior corneal asphericity in both groups (p<0.001). Thickness at the thinnest corneal point increased significantly after CL wear (p<0.0001). Coma-like and total HOA root mean square (RMS) error were significantly reduced following CL wearing in both fitting approaches (all p<0.05). CONCLUSION: Short-term rigid gas-permeable CL wear flattens the anterior cornea, increases the thinnest corneal thickness and reduces anterior surface HOA in keratoconus subjects. Apical-touch was associated with greater corneal flattening in comparison to three-point-touch lens wear.
Assuntos
Lentes de Contato de Uso Prolongado/efeitos adversos , Lentes de Contato/efeitos adversos , Topografia da Córnea , Aberrações de Frente de Onda da Córnea/etiologia , Ceratocone/terapia , Ajuste de Prótese/métodos , Adolescente , Adulto , Análise de Variância , Astigmatismo/etiologia , Astigmatismo/patologia , Aberrações de Frente de Onda da Córnea/patologia , Feminino , Humanos , Masculino , Adulto JovemRESUMO
PURPOSE: To investigate the effect of intraocular pressure (IOP) on wavefront aberrations in the anterior cornea, the internal optics, and the whole eye for myopic patients undergoing laser-assisted in situ keratomileusis (LASIK) surgery. METHODS: Fifty-seven myopic subjects were tested for wavefront aberrations in the anterior corneal surface and the whole eye using a corneal topographer and a wavefront analyzer, respectively, pre- and post-LASIK. The IOP and central corneal thickness (CCT) were measured with a noncontact tonometer and a pachymeter, respectively. Pre- and postoperative wavefront aberrations were compared, and the correlation between changes in the Zernike aberrations and the IOP was statistically tested. RESULTS: The mean root mean square (RMS) values of the higher-order aberrations (HOAs) were significantly increased in the anterior cornea, the internal optics, and the whole eye. The mean RMS values for a majority of Zernike terms were significantly increased, and systematic increases in the spherical aberrations were found in both the cornea and the whole eye. The spherical aberrations after LASIK were significantly correlated to the IOP (r = 0.59, P < 0.01, for oculus dexter [OD, right eye] and r = 0.49, P < 0.01, for oculus sinister [OS, left eye] in the cornea; r = 0.38, P < 0.01, for OD and r = 0.46, P < 0.01, for OS in the whole eye). CONCLUSIONS: IOP contributes to LASIK-induced HOAs, particularly spherical aberrations. To control the HOAs after LASIK, a new algorithm should include the IOP as a variable for laser surgery.