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1.
Pak J Pharm Sci ; 32(6(Supplementary)): 2859-2864, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32024625

RESUMO

Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake of antidepressants and electrolytic alterations in brain cancer (BC) patients and in control group (CG) who were taking frozen and canned food. The levels of electrolytes were compared in both groups through Mann-Whitney U test. The Odds Ratio (OR) and Relative Risks (RR) were calculated of having a specific occurrence or condition of brain cancer patients vs. controls. Majority (41.42%) patients were from the age group 33-57 years. There were 52% male and 47% female patients. There was more occurrence of dementia (41%) and depression (6%) in patients as compared to CG. 94% patients were found with dementia. 32% patients were having low levels of sodium and 43% were having low levels of potassium. High levels of potassium (26%) were found in CG. 76% patients and 73% controls were taking canned food in moderation. 69% patients and 50% controls were taking frozen food in moderation. The potassium levels (p value: 0.00001) and sodium levels (p value: 0.01468) were found at significant difference in brain cancer patients and control group. Statistically significantly higher odds of outcome (OR>1) and increased relative risks (RR) were reported in dementia, depression and intake of anti-depressants for BC vs. CG. This epidemiological study reports hyponatremia as a significantly different parameter between brain cancer patients and controls. Food's chemicals induce hyponatremia, which can disturb mental states to develop different neurological conditions.


Assuntos
Neoplasias Encefálicas/fisiopatologia , Demência/etiologia , Depressão/etiologia , Alimentos Congelados/efeitos adversos , Hiponatremia/induzido quimicamente , Adolescente , Adulto , Idoso , Antidepressivos/uso terapêutico , Neoplasias Encefálicas/metabolismo , Estudos de Casos e Controles , Criança , Demência/metabolismo , Depressão/tratamento farmacológico , Depressão/metabolismo , Feminino , Humanos , Hiponatremia/metabolismo , Masculino , Pessoa de Meia-Idade , Razão de Chances , Potássio/metabolismo , Prevalência , Risco , Sódio/metabolismo , Adulto Jovem
2.
Cell Biochem Funct ; 33(5): 266-76, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26059489

RESUMO

Consumption of cruciferous vegetables may protect against colorectal cancer. Cruciferous vegetables are rich in a number of bioactive constituents including polyphenols, vitamins and glucosinolates. Before consumption, cruciferous vegetables often undergo some form of processing that reduces their content of bioactive constituents and may determine whether they exert protective effects. The aim of this study was to compare the ability of raw and blanched-frozen broccoli to protect colonocytes against DNA damage, improve antioxidant status and induce xenobiotic metabolizing enzymes (XME). Fifteen Landrace × Large White male pigs were divided into five age-matched and weight-matched sets (79 days, SD 3, and 34·7 kg, SD 3·9, respectively). Each set consisted of siblings to minimize genetic variation. Within each set, pigs received a cereal-based diet, unsupplemented (control) or supplemented with 600 g day(-1) of raw or blanched-frozen broccoli for 12 days. The consumption of raw broccoli caused a significant 27% increase in DNA damage in colonocytes (p = 0·03) relative to the control diet, whereas blanched-frozen broccoli had no significant effect. Both broccoli diets had no significant effect on plasma antioxidant status or hepatic and colonic XME. This study is the first to report that the consumption of raw broccoli can damage DNA in porcine colonocytes.


Assuntos
Brassica/efeitos adversos , Colo/citologia , Colo/efeitos dos fármacos , Dano ao DNA/efeitos dos fármacos , Alimentos Congelados/efeitos adversos , Alimentos Crus/efeitos adversos , Animais , Brassica/enzimologia , Glicosídeo Hidrolases/metabolismo , Masculino , Suínos , Xenobióticos/metabolismo
3.
Artigo em Inglês | MEDLINE | ID: mdl-24784533

RESUMO

The presence of mercury, cadmium and lead has been studied in raw and processed fish and shellfish of the main traded species in Galicia (Spain) from at least 40 commercial outlets between January 2002 and October 2003. The results show that, according to European legislation, the products on the market are generally "safe", although the high levels of mercury in swordfish and shark are notable, with 22% of samples (n = 37) over the limit. We also indicate the relatively important contribution to mercury ingestion of widely consumed species, such as tuna, with 25% of samples (n = 378) over 0.25 mg kg⁻¹. Cadmium was over the limit (1.0 mg kg⁻¹) in 15% of the tested cephalopods (n = 79) and 29% of Chlamys sp. bivalves (n = 17).


Assuntos
Cádmio/análise , Contaminação de Alimentos , Chumbo/análise , Mercúrio/análise , Alimentos Marinhos/análise , Frutos do Mar/análise , Poluentes Químicos da Água/análise , Animais , Cádmio/toxicidade , Crustáceos , Dieta/efeitos adversos , Dieta/etnologia , União Europeia , Peixes , Inspeção de Alimentos , Alimentos em Conserva/efeitos adversos , Alimentos em Conserva/análise , Alimentos em Conserva/economia , Alimentos em Conserva/normas , Alimentos Congelados/efeitos adversos , Alimentos Congelados/análise , Alimentos Congelados/economia , Alimentos Congelados/normas , Fidelidade a Diretrizes , Humanos , Chumbo/toxicidade , Mercúrio/toxicidade , Moluscos , Medição de Risco , Alimentos Marinhos/efeitos adversos , Alimentos Marinhos/economia , Alimentos Marinhos/normas , Frutos do Mar/efeitos adversos , Frutos do Mar/economia , Frutos do Mar/normas , Espanha , Poluentes Químicos da Água/toxicidade
4.
Vet. Méx ; 26(1): 45-50, ene.-mar. 1995. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-173871

RESUMO

Con el objetivo de aislar e identificar Vibrio cholerae 01 de pescado fresco del centro distribuidor La Viga en México, D.F., se analizaron 120 pescados de tres especies: Lisa (Mugil cephalus), sierra (Scomberomorus maculatus) y bagre (Aurius sp). El tamaño de la muestra se determinó por conveniencia. Las muestras fueron analizadas mediante las técnicas descritas por el Método Microbiológico internacional de la Food and Drugs Administration (FDA). Se observó una gran cantidad de vibrios sp, pero aisló Vibrio cholerae 01. Diez pescados tuvieron vibrios que producen algún tipo de infección: Vibrio cholerae no-01, V. harveyi y V. vulnificus. Estos fueron aislados de 4 bagres y 1 lisa procedentes de Nayarit, Guerrero, Tamaulipas y Campeche; 2 sierras y 1 bagre procedentes de Tamaulipas y 2 bagres, uno de Tamaulipas y el otro de Campeche. Fue significativo identificar otros tipos de vibrios, también importantes, por el hecho de estar asociados a Vibrio cholerae y por ser capaces de producir daños serios al hombre


Assuntos
Animais , Vibrio cholerae/isolamento & purificação , Peixes/microbiologia , Alimentos Congelados/efeitos adversos , Bactérias Gram-Negativas/patogenicidade , Enteropatias/parasitologia , Cólera/veterinária , Contaminação de Alimentos/análise , Técnicas Microbiológicas/veterinária
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