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1.
Foot Ankle Surg ; 25(3): 348-353, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30321979

RESUMO

BACKGROUND: Recurrence of hallux valgus (HV) is a common complication after forefoot surgery for rheumatoid forefoot deformities. The aim of this study is to evaluate the impact of hindfoot malalignment on recurrence. METHODS: This was a retrospective observational study designed to analyze the radiographic outcomes of 87 feet in 64 patients with rheumatoid arthritis treated with a joint-preserving surgery for HV deformity. Differences in hindfoot alignment preoperatively between the recurrence and nonrecurrence groups was compared. RESULTS: There were no significant differences in hindfoot alignment preoperatively between groups. To estimate the impact of technical problems, the HV and intermetatarsal angles measured from radiographs 3 months postoperatively were compared between groups. The HV angles in the recurrence group were significantly larger than those in the nonrecurrence group (p=0.02). CONCLUSIONS: There were no significant differences between preoperative hindfoot malalignment and postoperative recurrence of HV in rheumatoid forefoot surgeries.


Assuntos
Artrite Reumatoide/cirurgia , Antepé Humano/cirurgia , Hallux Valgus/diagnóstico por imagem , Calcanhar/anormalidades , Complicações Pós-Operatórias/diagnóstico por imagem , Adulto , Idoso , Artrite Reumatoide/fisiopatologia , Feminino , Antepé Humano/diagnóstico por imagem , Antepé Humano/fisiopatologia , Hallux Valgus/cirurgia , Calcanhar/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Período Pré-Operatório , Radiografia , Recidiva , Estudos Retrospectivos
2.
Foot Ankle Surg ; 24(4): 309-313, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29409238

RESUMO

BACKGROUND: Gastrocnemius recession (GR) has been introduced for treatment of forefoot overload syndrome (FOS). We questioned if GR leads to an altered forefoot load and weakness of plantarflexors in those patients. METHODS: 26 patients suffering from FOS and gastrocnemius tightness underwent GR. A strength power analysis of plantar flexors and a pedobarography was performed. Clinical outcome was measured by Foot Function Index (FFI). RESULTS: Plantarflexors are impaired about 40% six weeks and around 10% 24 weeks following GR compared to the contralateral side. Patients experienced a pain relief and an improvement of ankle dorsiflexion from 2° to 15°. An increased contact time of the heel (15%) and a shift of metatarsal plantar pressure from lateral to medial could be demonstrated. CONCLUSIONS: This study suggests that GR leads to pain reduction by an increase in heel contact time and a shift of gait line to medial in patients with a FOS. Despite, a temporary impairment of muscle strength has to be considered.


Assuntos
Contratura/cirurgia , Pé/fisiopatologia , Antepé Humano/fisiopatologia , Marcha/fisiologia , Músculo Esquelético/cirurgia , Procedimentos Ortopédicos/métodos , Adulto , Contratura/fisiopatologia , Feminino , Pé/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Força Muscular/fisiologia , Músculo Esquelético/fisiopatologia , Amplitude de Movimento Articular/fisiologia , Síndrome
3.
Scand J Rheumatol ; 47(4): 259-269, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29336711

RESUMO

OBJECTIVE: To investigate serum interleukin-6 (IL-6), serum chitinase-3-like protein-1 (YKL-40), and plasma vascular endothelial growth factor (VEGF) as measures of disease activity and predictors of clinical remission and radiographic progression in two early rheumatoid arthritis (RA) randomized controlled trials (RCTs). METHOD: Treatment-naïve patients with early RA (< 6 months' duration) and active disease, participating in two investigator-initiated RCTs, were treated according to a predefined treat-to-target algorithm aiming at inflammatory control, using methotrexate (MTX) + cyclosporine versus MTX + placebo (CIMESTRA study, n = 150, 5 year follow-up) or MTX + adalimumab versus MTX + placebo (OPERA study, n = 180, 2 year follow-up). The 28-joint Disease Activity Score (DAS28) and conventional radiography [bilateral hands and feet at baseline, 2 years and 5 years (only CIMESTRA)] were obtained at baseline and during follow-up. Serum IL-6, serum YKL-40, and plasma VEGF were measured in baseline blood samples and during follow-up. Hypotheses regarding the biomarkers' relation with DAS28 and ability to predict clinical remission (DAS28 < 2.6) and radiographic progression (change in total Sharp van der Heijde score ≥ 2) were generated in CIMESTRA and validated in OPERA, by Spearman's correlation and logistic regression analyses. RESULTS: Baseline IL-6, YKL-40, and VEGF correlated significantly with DAS28 in CIMESTRA (r = 0.50, r = 0.36, r = 0.36, respectively, all p < 0.01) and these results were confirmed in OPERA patients (r = 0.52, p < 0.01; r = 0.18, p = 0.01; r = 0.23, p = 0.002, respectively). None of the biomarkers (absolute values or change) was predictive of clinical remission or radiographic progression at 2 or 5 years in either study. CONCLUSION: Serum IL-6, serum YKL-40, and plasma VEGF were significantly correlated with DAS28 at baseline, but did not have consistent predictive value for clinical remission or radiographic progression in two early RA RCTs.


Assuntos
Artrite Reumatoide/sangue , Proteína 1 Semelhante à Quitinase-3/sangue , Interleucina-6/sangue , Fator A de Crescimento do Endotélio Vascular/sangue , Adalimumab/uso terapêutico , Adulto , Antirreumáticos/uso terapêutico , Artrite Reumatoide/diagnóstico por imagem , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/fisiopatologia , Ciclosporina/uso terapêutico , Progressão da Doença , Feminino , Antepé Humano/diagnóstico por imagem , Antepé Humano/fisiopatologia , Articulação da Mão/diagnóstico por imagem , Articulação da Mão/fisiopatologia , Humanos , Masculino , Metotrexato/uso terapêutico , Pessoa de Meia-Idade , Prognóstico , Radiografia , Ensaios Clínicos Controlados Aleatórios como Assunto , Indução de Remissão , Índice de Gravidade de Doença
4.
J Foot Ankle Surg ; 56(5): 990-995, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28688712

RESUMO

The Cotton osteotomy or opening wedge medial cuneiform osteotomy is a useful adjunctive flatfoot reconstructive procedure that is commonly performed; however, the outcomes are rarely reported owing to the adjunctive nature of the procedure. The Cotton procedure is relatively quick to perform and effectively corrects forefoot varus deformity after rearfoot fusion or osteotomy to achieve a rectus forefoot to rearfoot relationship. Proper patient selection is critical because the preoperative findings of medial column joint instability, concomitant hallux valgus deformity, or degenerative joint disease of the medial column might be better treated by arthrodesis of the naviculocuneiform or first tarsometatarsal joints. Procedure indications also include elevatus of the first ray, which can be a primary deformity in hallux limitus or an iatrogenic deformity after base wedge osteotomy for hallux valgus. We undertook an institutional review board-approved retrospective review of 32 consecutive patients (37 feet) who had undergone Cotton osteotomy as a part of flatfoot reconstruction. All but 1 case (2.7%) had radiographic evidence of graft incorporation at 10 weeks. No patient experienced graft shifting. Three complications (8.1%) were identified, including 2 cases with neuritis (5.4%) and 1 case of delayed union (2.7%) that healed with a bone stimulator at 6 months postoperatively. Meary's angle improved an average of 17.75°, from -17.24°± 8.00° to 0.51°± 3.81°, and this change was statistically significant (p < .01). The present retrospective series highlights our experience with the use of the Cotton osteotomy as an adjunctive procedure in flatfoot reconstructive surgery.


Assuntos
Pé Chato/cirurgia , Antepé Humano/cirurgia , Osteotomia/métodos , Procedimentos de Cirurgia Plástica/métodos , Adolescente , Adulto , Idoso , Pinos Ortopédicos , Placas Ósseas , Criança , Estudos de Coortes , Feminino , Pé Chato/diagnóstico por imagem , Seguimentos , Antepé Humano/diagnóstico por imagem , Antepé Humano/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Osteotomia/instrumentação , Medição da Dor , Estudos Retrospectivos , Resultado do Tratamento , Suporte de Carga , Adulto Jovem
5.
Mod Rheumatol ; 27(5): 795-800, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27846766

RESUMO

OBJECTIVES: To clarify the difference of patient-based outcome between joint-preserving arthroplasty and resection-replacement arthroplasty in forefoot surgery for patients with rheumatoid arthritis (RA). METHODS: A total of 63 feet of 49 RA patients who underwent forefoot surgery were asked to answer pre-operative and post-operative self-administered foot evaluation questionnaire (SAFE-Q). Patients were treated with either (1) metatarsal head resection-replacement arthroplasty (28 feet, post-operative mean age 63.8 years, follow-up 4.2 years, DAS28-CRP 2.2) or (2) metatarsophalangeal joint-preserving arthroplasty (35 feet, post-operative mean age 63.1 years, follow-up 3.6 years, DAS28-CRP 2.1) at each surgeon's discretion. RESULTS: Mean pre-operative and post-operative subscale scores of SAFE-Q of group (1) and (2) were as follows. Pain and pain-related [(1) pre-op 36.8 to post-op 75.0 vs. (2) pre-op 42.2 to post-op 82.6], physical functioning and daily-living [(1) 43.2-68.8 vs. (2) 52.778.1], social functioning [(1) 44.3-72.0 vs. (2) 52.5-81.9], general health and well-being [(1) 48.4-68.4 vs. (2) 45.5-84.4], and shoe-related [(1) 30.1-50.3 vs. (2) 30.6-64.4]. Both general health and well-being subscale scores (p < 0.05) and shoe-related subscale scores (p < 0.05) were significantly more improved in group (2) compared with group (1). CONCLUSIONS: Joint-preserving arthroplasty resulted in better patient-based outcomes than resection-replacement arthroplasty.


Assuntos
Artrite Reumatoide , Artroplastia , Antepé Humano , Articulação Metatarsofalângica , Atividades Cotidianas , Idoso , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/psicologia , Artrite Reumatoide/cirurgia , Artroplastia/efeitos adversos , Artroplastia/métodos , Artroplastia/reabilitação , Autoavaliação Diagnóstica , Feminino , Antepé Humano/fisiopatologia , Antepé Humano/cirurgia , Humanos , Relações Interpessoais , Japão , Masculino , Articulação Metatarsofalângica/fisiopatologia , Articulação Metatarsofalângica/cirurgia , Pessoa de Meia-Idade , Avaliação de Resultados da Assistência ao Paciente , Período Perioperatório/métodos , Período Perioperatório/psicologia , Estudos Retrospectivos , Inquéritos e Questionários , Resultado do Tratamento
6.
Plast Reconstr Surg ; 138(5): 1099-1108, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27391833

RESUMO

BACKGROUND: Pedal fat pad atrophy is associated with pain, decreased tissue thickness, and increased foot pressures. To date, no objective studies investigating the use of fat grafting to the forefoot have been performed. The authors hypothesize that pedal fat grafting can reduce pain, increase tissue thickness, and decrease pedal pressures. METHODS: A prospective randomized study was performed to assess tissue thickness, pain, and foot pressures. Group 1 underwent fat grafting immediately with 1-year follow-up, and group 2 underwent conservative management for 1 year. RESULTS: Thirteen patients (two men and 11 women) constituted group 1 and 12 patients (four men and eight women) constituted group 2. Ten patients in group 1 underwent bilateral injections with a mean volume of 4.8 cc per foot. Mean follow-up time was 11.1 ± 5.4 months for group 1 and 13.8 ± 4.2 months for group 2. At 1 year, group 1 demonstrated improved foot function (p = 0.022), pain (p = 0.022), and work/leisure activities (p = 0.021). Group 1 had no change in tissue thickness, whereas in group 2, the right third metatarsal tissue thickness decreased significantly (p = 0.036). Foot pressures in group 1 did not improve; however, group 2 had a significant increase in left foot pressure (p = 0.011). When comparing the groups at 1 year, group 2 had significantly higher foot pressures and forces than group 1 (p < 0.05). CONCLUSIONS: Pedal fat grafting significantly improves pain and disability outcomes, and prevents against worsening foot pressures. Future analysis will reveal whether fat grafting has lasting efficacy. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.


Assuntos
Antepé Humano/patologia , Antepé Humano/cirurgia , Gordura Subcutânea/patologia , Gordura Subcutânea/transplante , Adulto , Idoso , Atrofia , Feminino , Seguimentos , Antepé Humano/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Pressão , Estudos Prospectivos , Transplante Autólogo , Resultado do Tratamento
7.
Bone Joint J ; 98-B(5): 641-6, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27143735

RESUMO

AIMS: The purpose of this study was to analyse the biomechanics of walking, through the ground reaction forces (GRF) measured, after first metatarsal osteotomy or metatarsophalangeal joint (MTP) arthrodesis. PATIENTS AND METHODS: A total of 19 patients underwent a Scarf osteotomy (50.3 years, standard deviation (sd) 12.3) and 18 underwent an arthrodesis (56.2 years, sd 6.5). Clinical and radiographical data as well as the American Orthopaedic Foot and Ankle Society (AOFAS) scores were determined. GRF were measured using an instrumented treadmill. A two-way model of analysis of variance (ANOVA) was used to determine the effects of surgery on biomechanical parameters of walking, particularly propulsion. RESULTS: Epidemiological, radiographical and clinical data were comparable in the two groups and better restoration of propulsive function was found after osteotomy as shown by ANOVA (two way: surgery × foot) with a surgery effect on vertical forces (p < 0.01) and a foot effect on anteroposterior impulse (p = 0.01). CONCLUSION: Patients who underwent Scarf osteotomy had a gait pattern similar to that of their non-operated foot, whereas those who underwent arthrodesis of the first (metatarsophalangeal) MTP joint did not totally recover the propulsive forces of the forefoot. TAKE HOME MESSAGE: The main findings of this study were that after surgical correction for hallux valgus, patients who underwent scarf osteotomy had a gait pattern similar to that of their non-operated foot in terms of forefoot propulsive forces (Fz3, Iy2), whereas those who underwent arthrodesis of the first MTP joint had not. Cite this article: Bone Joint J 2016;98-B:641-6.


Assuntos
Artrodese , Antepé Humano/fisiopatologia , Marcha/fisiologia , Hallux Valgus/fisiopatologia , Hallux Valgus/cirurgia , Osteotomia , Fenômenos Biomecânicos/fisiologia , Estudos Transversais , Feminino , Humanos , Masculino , Ossos do Metatarso/cirurgia , Articulação Metatarsofalângica/cirurgia , Pessoa de Meia-Idade , Caminhada/fisiologia
8.
Clin Rheumatol ; 35(9): 2333-8, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27225246

RESUMO

Dactylitis is a common feature of psoriatic arthritis (PsA); local physical trauma has been identified as a possible contributing factor. The aim of this study was to explore differences in forefoot plantar pressures in patients with PsA with and without dactylitis and compare to healthy controls. Thirty-six participants were recruited into three groups: group A PsA plus a history of dactylitis; group B PsA, no dactylitis; group C control participants. Forefoot plantar pressures were measured barefoot and in-shoe at the left second and fourth toes and corresponding metatarsophalangeal joints. Temporal and spatial parameters were measured and data from the foot impact scale for rheumatoid arthritis (FIS-RA), EQ5D and health assessment questionnaire (HAQ) were collected. Pressure time integral peak plantar pressure, and contact time barefoot and in-shoe were not significantly different between groups. Temporal and spatial parameters reported no significant differences between groups. ANOVA analysis and subsequent post hoc testing using Games-Howell test yielded significance in FIS-RA scores between both PsA groups versus controls, A p ≤ 0.0001 and PsA group B p < 0.0001 in the FIS-RA impairment and footwear domain, PsA group A p < 0.03 and PsA group B p ≤ 0.05 in the FIS-RA activity and participation domain compared to controls. This is the first exploratory study to investigate forefoot plantar pressures in patients with and without historical dactylitis in PsA. FIS-RA scores indicate PsA patients have significant limitations compared to controls, although a history of dactylitis does not appear to worsen patient reported outcomes.


Assuntos
Artrite Psoriásica/fisiopatologia , Doenças do Pé/fisiopatologia , Antepé Humano/fisiopatologia , Marcha/fisiologia , Dedos do Pé/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Artrite Psoriásica/complicações , Feminino , Doenças do Pé/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Pressão , Sapatos , Adulto Jovem
9.
J Med Invest ; 63(1-2): 38-44, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27040050

RESUMO

The purpose of this study was to investigate the changes in foot function, disease activity, and disability in patients with RA after resection arthroplasty of the forefoot (arthroplasty). Arthroplasty was performed on 11 patients with RA. All study patients underwent clinical assessment to measure disease activity (Disease Activity Score in 28 Joints-C-reactive protein, DAS28-CRP), disability (Health Assessment Questionnaire-Disability Index, HAQ-DI) and foot function (Foot Function Index, FFI) at the following stages: preoperatively and 1, 3, and 12 months after surgery. Following arthroplasty, foot function improved significantly, as assessed by FFI total and subscales (pain, disability, and limitation of activity) (P<0.001, P<0.001, P<0.001, and P=0.002, respectively). Disease activity was significantly improved in relation to DAS28-CRP and its subscales of number of swollen joints and patient global assessment (PtGA) (P=0.033, P=0.008, and P=0.038, respectively). There was no significant difference in disability, as assessed by the HAQ-DI and its subscale, HAQ-walking (P=0.150 and P=0.597, respectively). Foot function improved significantly after arthroplasty, and was maintained at 12 months postoperatively. Additionally, our study showed that disease activity and its subscale PtGA improved after arthroplasty.


Assuntos
Artrite Reumatoide/cirurgia , Antepé Humano/cirurgia , Idoso , Artrite Reumatoide/diagnóstico por imagem , Artrite Reumatoide/fisiopatologia , Artroplastia , Proteína C-Reativa/metabolismo , Feminino , Antepé Humano/diagnóstico por imagem , Antepé Humano/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença
10.
Int Orthop ; 40(4): 745-9, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26842388

RESUMO

PURPOSE: This study examines the responsiveness of the Foot Functional Index (FFI) and Leeds Foot Impact Scale for Rheumatoid Arthritis (LFIS-RA) in rheumatoid arthritis (RA) patients receiving a forefoot or hindfoot reconstruction. METHODS: This was a prospective cohort study including 30 rheumatoid arthritis patients with severe rheumatoid foot deformities in need for surgical correction. Responsiveness was measured using distribution-based methods (standardized effect size, standardized response mean and Guyatt responsiveness ratio) and anchor-based methods (receiver operating characteristics curves and correlation analyses) by making use of an anchor question. To examine the depth of the questionnaires we measured the floor and ceiling effects. RESULTS: The study population consisted of three males and 27 females, with a mean age of 62 years. The mean follow-up time was 38 months. Twenty-two feet received a forefoot reconstruction and eight feet a triple arthrodesis. For the FFI the SES was -0.80, SRM was -0.85 and the GRR was -1.25. For the LFIS-RA the SES was 0.58, SRM was 0.58 and the GRR was 0.88. The AUC was 0.741 and 0.645 for FFI and LFIS, respectively. Contrary to the LFIS-RA, the FFI showed a significant correlation between change score and the anchor question. Both questionnaires did not show a significant floor or ceiling effect. CONCLUSION: The FFI showed a large responsiveness and the LFIS- RA showed moderate responsiveness in rheumatoid arthritis patients receiving forefoot or hindfoot surgery, without floor or ceiling effects in both questionnaires.


Assuntos
Artrite Reumatoide/cirurgia , Artrodese/métodos , Deformidades Adquiridas do Pé/cirurgia , Antepé Humano/fisiopatologia , Adulto , Idoso , Artrite Reumatoide/fisiopatologia , Estudos de Coortes , Feminino , Deformidades Adquiridas do Pé/fisiopatologia , Antepé Humano/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Procedimentos de Cirurgia Plástica , Sensibilidade e Especificidade , Inquéritos e Questionários
11.
J Orthop Surg (Hong Kong) ; 23(3): 357-60, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26715718

RESUMO

PURPOSE: To investigate the association between medial tibial stress syndrome (MTSS) and morphology and flexibility of the foot arches. METHODS: 131 feet from 74 healthy subjects and 31 feet from 27 patients with MTSS were classified as normal feet (n=78 in 40 subjects), flat feet (n=53 in 34 subjects), or MTSS feet (n=31 in 27 patients). The medial longitudinal arch (MLA) ratio and the transverse arch length (TAL) were measured in both rearfoot and forefoot loading positions. The difference between the 2 positions indicated the flexibility of the MLA (diff-MLA ratio) and the transverse arch (diff- TAL). RESULTS: The MLA ratio was higher in normal feet than MTSS feet or flat feet (15.1% vs. 12.8% vs. 12.3%, p<0.001). The diff-TAL was lower in MTSS feet than normal feet or flat feet (0.4% vs. 0.8% vs. 0.9%, p<0.001]). The 3 groups were comparable in terms of the diff-MLA ratio and the TAL. Respectively for the MLA ratio and the diff-TAL, the cut-off value was 11.9% and 0.61% based on the Youden index. The sensitivity, specificity, and odds ratio of the cut-off value were 0.4, 0.9, and 4.8 for the MLA ratio, and 0.6, 0.7, and 9.8 for the diff-TAL, respectively. CONCLUSION: Decreased flexibility of the transverse arch and decreased MLA ratio are risk factors for MTSS. In contrast, the flexibility of the MLA and the height of the transverse arch were not risk factors for MTSS.


Assuntos
Pé Chato/fisiopatologia , Antepé Humano/fisiopatologia , Síndrome do Estresse Tibial Medial/fisiopatologia , Amplitude de Movimento Articular/fisiologia , Adolescente , Estudos de Casos e Controles , Feminino , Pé Chato/diagnóstico , Pé Chato/etiologia , Humanos , Masculino , Síndrome do Estresse Tibial Medial/diagnóstico , Síndrome do Estresse Tibial Medial/etiologia , Razão de Chances , Fatores de Risco , Sensibilidade e Especificidade , Suporte de Carga/fisiologia , Adulto Jovem
12.
Arq. bras. cardiol ; 104(5): 417-425, 05/2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-748154

RESUMO

Introduction: Although diuretics are mainly used for the treatment of acute decompensated heart failure (ADHF), inadequate responses and complications have led to the use of extracorporeal ultrafiltration (UF) as an alternative strategy for reducing volume overloads in patients with ADHF. Objective: The aim of our study is to perform meta-analysis of the results obtained from studies on extracorporeal venous ultrafiltration and compare them with those of standard diuretic treatment for overload volume reduction in acute decompensated heart failure. Methods: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials databases were systematically searched using a pre‑specified criterion. Pooled estimates of outcomes after 48 h (weight change, serum creatinine level, and all-cause mortality) were computed using random effect models. Pooled weighted mean differences were calculated for weight loss and change in creatinine level, whereas a pooled risk ratio was used for the analysis of binary all-cause mortality outcome. Results: A total of nine studies, involving 613 patients, met the eligibility criteria. The mean weight loss in patients who underwent UF therapy was 1.78 kg [95% Confidence Interval (CI): −2.65 to −0.91 kg; p < 0.001) more than those who received standard diuretic therapy. The post-intervention creatinine level, however, was not significantly different (mean change = −0.25 mg/dL; 95% CI: −0.56 to 0.06 mg/dL; p = 0.112). The risk of all-cause mortality persisted in patients treated with UF compared with patients treated with standard diuretics (Pooled RR = 1.00; 95% CI: 0.64–1.56; p = 0.993). Conclusion: Compared with standard diuretic therapy, UF treatment for overload volume reduction in individuals suffering from ADHF, resulted in significant reduction of body weight within 48 h. However, no significant decrease of serum creatinine level or reduction of all-cause mortality ...


Introdução: Embora os diuréticos sejam utilizados como o principal tratamento na insuficiência cardíaca aguda descompensada, sua significativa taxa de complicações e respostas inadequadas levou ao uso de ultrafiltração extracorpórea como uma alternativa. Objetivo: Realizar uma meta-análise de estudos de ultrafiltração venosa extracorpórea e diuréticos no tratamento de sobrecarga hídrica na insuficiência cardíaca aguda descompensada. Métodos: MEDLINE, EMBASE e o banco de dados do Cochrane Central Register of Controlled Trials foram pesquisados sistematicamente usando um critério pré-estabelecido. Estimativas combinadas para os resultados na alteração de peso em 48 horas, creatinina sérica e mortalidade por todas as causas foram calculados utilizando modelos de efeitos aleatórios. As diferenças entre as médias ponderadas combinadas foram calculadas para a perda de peso e alteração nos níveis de creatinina e relação risco partilhado foi utilizada para o resultado binário de todas as causas de mortalidade. Resultados: Nove estudos foram considerados elegíveis para a análise, com inclusão de 613 pacientes. Pacientes submetidos a ultrafiltração perderam em média 1,78kg (intervalo de confiança [IC] 95% -2,65 a 0,91kg, p < 0,001) quando comparados com pacientes submetidos à terapia diurética padrão. Os níveis de creatinina pós-intervenção, no entanto, não diferiram entre os grupos (diferença média de -0,25 mg/dL CI 95% -0,56 a 0,06mg/dL p = 0,112). Não observamos evidências de redução de risco de mortalidade por todas as causas em pacientes submetidos à UF quando comparados àqueles tratados com terapia diurética padrão (RR combinado = 1,00 CI 95% 0,64 1,56, p = 0,993). Conclusão: Quando comparado à terapia diurética padrão, o uso de UF no tratamento de sobrecarga hídrica em ICAD resultou em uma redução significativa de peso em 48 horas. No entanto, não foi observada melhoria significativa na redução dos níveis de creatinina ou na taxa de ...


Assuntos
Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pé Diabético/etiologia , Neuropatias Diabéticas/fisiopatologia , Pé/fisiopatologia , Pressão , Caminhada/fisiologia , Análise de Variância , Distinções e Prêmios , Biofísica , Estudos de Casos e Controles , Antepé Humano/fisiopatologia , Sociedades Científicas
13.
Clin Orthop Relat Res ; 473(5): 1737-43, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25421955

RESUMO

BACKGROUND: Idiopathic clubfoot correction is commonly performed using the Ponseti method and is widely reported to provide reliable results. However, a relapsed deformity may occur and often is treated in children older than 2.5 years with repeat casting, followed by an anterior tibial tendon transfer. Several techniques have been described, including a whole tendon transfer using a two-incision technique or a three-incision technique, and a split transfer, but little is known regarding the biomechanical effects of these transfers on forefoot and hindfoot motion. QUESTIONS/PURPOSE: We used a cadaveric foot model to test the effects of three tibialis anterior tendon transfer techniques on forefoot positioning and production of hindfoot valgus. METHODS: Ten fresh-frozen cadaveric lower legs were used. We applied 150 N tension to the anterior tibial tendon, causing the ankle to dorsiflex. Three-dimensional motions of the first metatarsal, calcaneus, and talus relative to the tibia were measured in intact specimens, and then repeated after each of the three surgical techniques. RESULTS: Under maximum dorsiflexion, the intact specimens showed 6° (95% CI, 2.2°-9.4°) forefoot supination and less than 3° (95% CI, 0.4°-5.3°) hindfoot valgus motion. All three transfers provided increased forefoot pronation and hindfoot valgus motion compared with intact specimens: the three-incision whole transfer provided 38° (95% CI, 33°-43°; p < 0.01) forefoot pronation and 10° (95% CI, 8.5°-12°; p < 0.01) hindfoot valgus; the split transfer, 28° (95% CI, 24°-32°; p < 0.01) pronation, 9° (95% CI, 7.5°-11°; p < 0.01) valgus; and the two-incision transfer, 25° (95% CI, 20°-31°; p < 0.01) pronation, 6° (95% CI, 4.2°-7.8°; p < 0.01) valgus. CONCLUSION: All three techniques may be useful and deliver varying degrees of increased forefoot pronation, with the three-incision whole transfer providing the most forefoot pronation. Changes in hindfoot motion were small. CLINICAL RELEVANCE: Our study results show that the amount of forefoot pronation varied for different transfer methods. Supple dynamic forefoot supination may be treated with a whole transfer using a two-incision technique to avoid overcorrection, while a three-incision technique or a split transfer may be useful for more resistant feet. Confirmation of these findings awaits further clinical trials.


Assuntos
Pé Torto Equinovaro/cirurgia , Antepé Humano/fisiopatologia , Complicações Pós-Operatórias/fisiopatologia , Transferência Tendinosa/métodos , Tendões/cirurgia , Fenômenos Biomecânicos , Cadáver , Pé Torto Equinovaro/diagnóstico , Pé Torto Equinovaro/fisiopatologia , Humanos , Pronação , Amplitude de Movimento Articular , Recidiva , Reoperação , Transferência Tendinosa/efeitos adversos , Tendões/fisiopatologia , Suporte de Carga
14.
Mod Rheumatol ; 25(3): 367-72, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25381729

RESUMO

OBJECTIVE: To elucidate the systemic and local risk factors and the effect of surgical procedures for delayed wound healing after forefoot surgery in patients with rheumatoid arthritis (RA). METHODS: Fifty forefoot surgeries were performed in 39 patients using resection arthroplasty or a joint-preserving procedure (25 feet for each procedure). The associations between the occurrence of delayed wound healing and clinical variables, radiological assessment, or surgical procedures were analyzed. RESULTS: Delayed wound healing was recorded in nine feet of eight patients. The duration of RA was significantly longer in the delayed healing group than that in the healed group. Age, sex, smoking history, concomitant diabetes, and RA medication did not differ between the groups. Radiological evaluation showed significant differences between groups in metatarsophalangeal dorsal flexion angle. The shortened length of the fourth and the fifth metatarsal bones affected the occurrence of the complication. The joint-preserving procedure had significantly less delayed wound healing compared with resection arthroplasty. CONCLUSIONS: Preoperative dorsoplantar deformity and perioperative tissue damage can cause delayed wound healing after forefoot surgery in RA patients.


Assuntos
Artrite Reumatoide/fisiopatologia , Deformidades do Pé/cirurgia , Antepé Humano/fisiopatologia , Ossos do Metatarso/cirurgia , Cicatrização/fisiologia , Adulto , Idoso , Artrite Reumatoide/cirurgia , Artrodese , Artroplastia , Feminino , Deformidades do Pé/fisiopatologia , Antepé Humano/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
15.
Clin Podiatr Med Surg ; 31(3): 405-13, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24980930

RESUMO

The supination of the forefoot that develops with adult acquired flatfoot is defined as forefoot supinatus. This deformity is an acquired soft tissue adaptation in which the forefoot is inverted on the rearfoot. Forefoot supinatus is a reducible deformity. Forefoot supinatus can mimic, and often be mistaken for, a forefoot varus. A forefoot varus differs from forefoot supinatus in that a forefoot varus is a congenital osseous deformity that induces subtalar joint pronation, whereas forefoot supinatus is acquired and develops because of subtalar joint pronation. This article discusses the acquired form of forefoot supinatus.


Assuntos
Pé Chato/fisiopatologia , Antepé Humano/fisiopatologia , Supinação/fisiologia , Adulto , Pé Chato/cirurgia , Antepé Humano/diagnóstico por imagem , Antepé Humano/cirurgia , Humanos , Procedimentos Ortopédicos , Exame Físico , Radiografia , Amplitude de Movimento Articular/fisiologia
16.
J Foot Ankle Surg ; 53(4): 415-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24958073

RESUMO

Hallux valgus with or without first ray insufficiency has been strongly implicated as a contributing factor in lesser metatarsal overload. The principle goals of a bunionectomy are to relieve the pain, correct the deformity, and restore first metatarsophalangeal joint congruity. Until now, little evidence has been available to assess the effects of bunionectomy procedures on forefoot pressure. The primary aim of the present prospective study was to evaluate the preoperative and postoperative plantar pressures after 2 specific bunionectomies: the chevron bunionectomy and Lapidus arthrodesis. A total of 68 subjects, 34 in each group, were included for radiographic and pedographic evaluation. Both procedures demonstrated radiographic improvements in the mean intermetatarsal and hallux abductus angles. The mean hallux plantar pressure decreased significantly in both procedure groups (p < .001). However, Lapidus group exhibited an increase in the mean fifth metatarsal head plantar pressure (p = .008) and pressure under the fifth metatarsal as a percentage of the total forefoot pressure (p = .01). Furthermore, the pressure under the second metatarsal as a percentage of the total forefoot pressure decreased significantly (p = .01). This study suggests that the Lapidus arthrodesis and chevron bunionectomy both provide correction for hallux valgus deformity, but when comparing forefoot load sharing pressures, the Lapidus arthrodesis appeared to have greater influence on the load sharing distribution of forefoot pressure than did the bunionectomy employing the chevron osteotomy.


Assuntos
Artrodese , Antepé Humano/fisiopatologia , Hallux Valgus/cirurgia , Idoso , Feminino , Antepé Humano/cirurgia , Hallux Valgus/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Pressão
17.
Clin Podiatr Med Surg ; 31(2): 233-46, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24685190

RESUMO

The scarf osteotomy has been used and researched extensively for many years for the correction of hallux valgus deformity in both the adolescent and adult populations. It is an inherently stable construct, which allows for early weight bearing and early return to activities of daily living. The scarf procedure has a wide array of surgical indications with great reproducibility and a low complication rate, and it can be performed bilaterally simultaneously, with long-term predictability. Once the scarf procedure is mastered, it is a rewarding and predictable operation for both the surgeon and patient.


Assuntos
Hallux Valgus/cirurgia , Osteotomia/métodos , Fenômenos Biomecânicos , Antepé Humano/fisiopatologia , Hallux Valgus/fisiopatologia , Humanos , Ossos do Metatarso/irrigação sanguínea , Resultado do Tratamento
18.
Gait Posture ; 39(1): 321-7, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-23973353

RESUMO

The Ponseti technique for treatment for Congenital Talipes Equinovarus (CTEV) was introduced in the authors' institution in 2001, substituting a more traditional orthopaedic approach which involved surgery. There is currently limited published information regarding the differences in clinical outcomes between these two techniques, particularly in relation to plantar pressure analysis. This study aims to determine differences in pedobarographic outcome in children with CTEV, treated with either a surgical or Ponseti approach. A high resolution pedobarograph was used to record plantar pressure distribution in 52 children with CTEV and 26 children with typical development. Data were imported into Matlab where a custom programme was developed for processing and analysing pedobarographic recordings. There were significant differences in both treatment groups compared to the typically developed group (p<0.05) for most measurements. The most salient differences between treatment groups were (i) at the hind-foot where the Ponseti group had significantly lower maximum peak pressures (p<0.05); (ii) at the lateral mid-foot where children treated by the Ponseti approach showed significantly larger peak force (p<0.001), average peak pressure (p<0.001) and maximum peak pressure (p<0.01); (iii) at the lateral fore-foot where the surgical group showed lower average peak pressure (p<0.05); and (iv) in the medial/lateral fore-foot ratio where the Ponseti group showed significantly lower values (p<0.05). Plantar pressure analysis is a complementary measurement for the assessment of gait in children with CTEV. Data presented in this study showed that while there were deviations in children with CTEV, the differences observed between treatment groups suggest children in the Ponseti group have some level of under correction or recurrence.


Assuntos
Moldes Cirúrgicos , Pé Torto Equinovaro/terapia , Pé/fisiopatologia , Manipulação Ortopédica/métodos , Pressão , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Pé/fisiologia , Antepé Humano/fisiologia , Antepé Humano/fisiopatologia , Marcha , Humanos , Masculino , Procedimentos Ortopédicos/métodos , Estudos Retrospectivos , Resultado do Tratamento
19.
Clin Podiatr Med Surg ; 30(3): 283-93, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23827487

RESUMO

After 4 to 8 weeks of normal primary bone healing, rigid internal fixation is no longer required. Newer generation absorbable implants have become reliable and cost-effective alternatives to metallic hardware. Modern implants are formulated to have increased strength and smoother resorption over the course of 18 to 24 months, which decreases the possibility of local inflammation. Historically, bioresorbable screws can be time consuming to insert, but newer devices are being developed that help ease their insertion. A case of a bunionectomy is presented with double osteotomy on a 40-year-old nurse fixated with polyglycolic acid and poly-l-lactic acid copolymer screws.


Assuntos
Implantes Absorvíveis , Antepé Humano/cirurgia , Hallux Valgus/cirurgia , Osteotomia/métodos , Adulto , Materiais Biocompatíveis , Placas Ósseas , Parafusos Ósseos , Feminino , Antepé Humano/diagnóstico por imagem , Antepé Humano/fisiopatologia , Fixação Interna de Fraturas/instrumentação , Consolidação da Fratura/fisiologia , Hallux Valgus/diagnóstico por imagem , Humanos , Ácido Láctico/farmacologia , Poliésteres , Ácido Poliglicólico/farmacologia , Polímeros/farmacologia , Radiografia , Resultado do Tratamento
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