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1.
J Craniomaxillofac Surg ; 52(4): 472-476, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38378367

RESUMO

This study compares condylar volumetric asymmetry and facial asymmetry in patients with cleft lip and/or palate (CLP) and controls. The mandibular condyle is important to facial growth, but its role in facial asymmetry for those with CLP has not been described. Condylar volumes and mandibular asymmetry were retrospectively calculated using Mimics Version 23.0 (Materialise, Leuven, Belgium) from patients with CLP undergoing computed tomography (CT) imaging and a cohort of controls. A total of 101 participants, 60 with CLP and 41 controls, had mean condylar volumetric asymmetry of 16.4 ± 17.4 % (CLP) and 6.0 ± 4.0 % (controls) (p = 0.0002). Patients with CLP who had clinically significant chin deviation (>4 mm) had more asymmetric condyles than those without significant chin deviation (p = 0.003). The chin deviated toward the smaller condyle in patients with facial asymmetry more often than in patients without facial asymmetry (81 % vs. 62 %, p = 0.033). While controls had some degree of condylar asymmetry, it tended to be milder and not associated with facial asymmetry. There is a greater degree of condylar volumetric asymmetry in patients with CLP compared to individuals in the general population. Clinically significant facial asymmetry in CLP is associated with a higher degree of condylar asymmetry, with the facial midline deviating toward the smaller condyle.


Assuntos
Fenda Labial , Fissura Palatina , Humanos , Fenda Labial/complicações , Fenda Labial/diagnóstico por imagem , Côndilo Mandibular/diagnóstico por imagem , Côndilo Mandibular/cirurgia , Estudos Retrospectivos , Assimetria Facial/diagnóstico por imagem , Assimetria Facial/complicações , Fissura Palatina/complicações , Fissura Palatina/diagnóstico por imagem , Imageamento Tridimensional
2.
J Craniomaxillofac Surg ; 52(1): 40-47, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38129190

RESUMO

The study analyzed vascular variations in microtia associated with hemifacial microsomia (HFM). A retrospective analysis was conducted on 47 patients with microtia and HFM, who underwent computed tomography angiography between November 2011 and May 2022. The vascular course and branching supplying the TPF were analyzed. Craniometric measurements were conducted to determine the horizontal distance from the porion and fronto-zygomatic suture (F-Z suture) to the vessels. On the affected side, the TPF was primarily supplied by either the superficial temporal artery (STA) or the postauricular artery-originated STA (Po-STA). The Po-STA (n = 29) was more prevalent than the STA (n = 18), and mostly exhibited a single frontal branch (n = 20). Craniometric analysis revealed that the Po-STA was closer to the porion, ear vestige, and F-Z suture than the STA on the non-affected side. Furthermore, a significant correlation was observed between the severity of mandibular hypoplasia and presence of Po-STA variation (Cramer's V = 0.498, p = 0.005). Microtia associated with HFM exhibits vascular variations in the TPF - in particular, a unique Po-STA variation. The Po-STA is prone to injury during ear reconstruction because of its proximity to the external auditory canal and ear vestige. Surgeons should be cautious of these anatomical variations for safer ear reconstruction procedures, and utilize preoperative imaging for meticulous planning.


Assuntos
Microtia Congênita , Síndrome de Goldenhar , Humanos , Síndrome de Goldenhar/diagnóstico por imagem , Síndrome de Goldenhar/cirurgia , Síndrome de Goldenhar/complicações , Estudos Retrospectivos , Assimetria Facial/complicações , Microtia Congênita/cirurgia , Fáscia/transplante
3.
Eur Rev Med Pharmacol Sci ; 27(22): 11073-11081, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-38039038

RESUMO

OBJECTIVE: This study aims to determine the occurrence of complications before and after the treatment of facial fractures, as well as the impact of the factors on the treatment results and evaluation of their relationships. PATIENTS AND METHODS: This is a prospective case-control study comprising 90 patients aged between 18 and 65 with facial fractures. Depending on the treatment method, patients were divided into three groups: those treated surgically using a transcutaneous approach, those treated surgically using a transmucosal approach, and those treated conservatively (control group). Following complications before and after treatment were compared: malocclusions, paresthesias, facial asymmetry, diplopia, and limited mouth opening. The follow-up period after the treatment of choice was six months. RESULTS: There was a significant reduction in complications after treatment: malocclusion, paresthesia, facial asymmetry, and limited mouth opening. Regarding the transcutaneous approach, there is a substantial reduction in the number of complications after treatment, such as malocclusions (p=0.008), paresthesias (p=0.004), and facial asymmetries (p<0.001). Similar results were obtained for the transmucosal approach. Pain intensity positively correlated with preoperative complications: malocclusion, paresthesias, and facial asymmetry. The range of mouth opening had a negative interdependence with malocclusion before and after treatment with infection, fractura male sanata, malocclusion, paresthesias, postoperative level of mouth opening, and damage to the facial nerve. CONCLUSIONS: There is no difference in the reduction of preoperative and postoperative complications related to surgery when an incision is made through the skin or mucosa. Malocclusions, paresthesias, and facial asymmetry are reduced through surgical methods.


Assuntos
Má Oclusão , Fraturas Mandibulares , Humanos , Masculino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Estudos de Casos e Controles , Assimetria Facial/complicações , Assimetria Facial/cirurgia , Parestesia , Fraturas Mandibulares/complicações , Fraturas Mandibulares/cirurgia , Resultado do Tratamento , Má Oclusão/cirurgia , Má Oclusão/complicações , Fixação Interna de Fraturas/métodos
5.
J Oral Rehabil ; 50(9): 845-851, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37133441

RESUMO

BACKGROUND: Condylar hyperplasia (CH) is a rare condition characterised by excessive unilateral growth of the mandibular condyle after cessation of growth on the contralateral side causing facial asymmetry, being more prevalent in the second and third decades. OBJECTIVE: The aim of this study was to determine the utility of vascular endothelial growth factor (VEGF-A) as a diagnostic and prognostic factor in condylar hyperplasia, and to determine its potential viability as a therapeutic target. METHODS: This is a case-control study, where 17 mandibular condyles specimens were collected from 17 patients treated for active mandibular condyle hyperplasia and three unaffected human mandibular condyles from cadavers will serve as the control group. The samples were immunostained with VEGF-A antibody and evaluated on both quantity and intensity of staining. RESULTS: VEGF-A was qualitatively found to be greatly upregulated in patients with condylar hyperplasia. CONCLUSION: VEGF-A was qualitatively found to be upregulated in patients affected by CH, validating VEGF-A as a potential diagnostic, prognostic and therapeutic target.


Assuntos
Má Oclusão , Côndilo Mandibular , Humanos , Estudos de Casos e Controles , Assimetria Facial/complicações , Assimetria Facial/patologia , Hiperplasia/complicações , Hiperplasia/patologia , Má Oclusão/etiologia , Côndilo Mandibular/patologia , Fator A de Crescimento do Endotélio Vascular
6.
J Fr Ophtalmol ; 46(4): 388-392, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36759247

RESUMO

BACKGROUND: Intracranial arachnoid cysts are cystic congenital malformations, filled with cerebrospinal fluid (CSF) originating from the arachnoid membrane. Generally, giant arachnoid cysts present with symptoms related to increased intracranial pressure, hydrocephalus or cognitive disorders, endocrinological problems, growth retardation, seizures, headache, and nonspecific symptoms such as dizziness. They can be detected by imaging when they become symptomatic or incidentally in childhood and adulthood. Our case was referred to our clinic because of ptosis and facial asymmetry found on examination. Subsequently, a intracranial giant arachnoid cyst was found incidentally on cranial computed tomography (CT). CASE: In an 18-month-old male infant admitted with ptosis, left frontal bulging and a dystopic globe with ptosis of the left upper lid were noted. The left half of the facial region and the left nostril also appeared to be asymmetrically elongated downward relative to the right. Fundus examination revealed an optic disc coloboma in the left eye. On general physical examination, he was unable to walk. A giant fronto-temporo-parietal arachnoid cyst with the cerebral parenchyma shifted 2cm to the right of the midline was observed on cranial CT. After a cysto-peritoneal shunt was performed, the physical appearance of our patient returned to normal. CONCLUSION: Ptosis cases accompanied by abnormalities such as optic disc coloboma and facial asymmetry should be evaluated for possible midline defects and intracranial pathologies prior to eyelid surgery.


Assuntos
Cistos Aracnóideos , Coloboma , Lactente , Humanos , Criança , Masculino , Cistos Aracnóideos/complicações , Cistos Aracnóideos/diagnóstico , Cistos Aracnóideos/cirurgia , Coloboma/complicações , Assimetria Facial/complicações , Assimetria Facial/diagnóstico , Tomografia Computadorizada por Raios X , Cefaleia/etiologia , Imageamento por Ressonância Magnética
7.
Artigo em Inglês | MEDLINE | ID: mdl-36529674

RESUMO

Many options exist in the diagnosis and management of condylar osteochondroma. The purpose of this study was to provide a congregate information concerning treatment of the osteochondroma involving the mandibular condyle. The search was conducted in PubMed, Google Scholar, Semantic Scholar, and Cochrane database until February 2022. Twenty-seven studies were included for the final review. The review included 439 patients who underwent surgical management for mandibular condylar osteochondroma. The position of osteochondroma was mentioned in 13 studies. Preauricular, retromandibular, endaural, submandibular, transzygomatic, and intraoral approaches were used for approaching the tumor. Surgical techniques included resection, conservative condylectomy, and total condylectomy. Concomitant orthognathic surgery was performed along with tumor resection in 19 studies. In the entire review, the recurrence rate was 0.22% (1/439). The results of the meta-analysis showed that 2 studies reported significant malocclusion events after surgical therapy. Total joint replacement after tumor resection has a higher improvement in maximal mouth opening (8 mm) compared with vertical ramus osteotomy and no reconstruction groups, which have similar improvements (6 mm). The mainstay of treatment of osteochondroma is surgical excision either as condylectomy or conservative condylectomy. Among the various reconstruction modalities, total joint replacement showed better improvement in mouth opening. Adjunct procedures like orthodontic and orthognathic surgery have an important role in holistic management of severe cases. The treating surgeon must choose the surgical procedures in a pragmatic way.


Assuntos
Neoplasias Mandibulares , Osteocondroma , Humanos , Côndilo Mandibular/cirurgia , Côndilo Mandibular/patologia , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Osteotomia/métodos , Resultado do Tratamento , Osteocondroma/diagnóstico por imagem , Osteocondroma/cirurgia , Osteocondroma/complicações , Assimetria Facial/complicações , Assimetria Facial/patologia , Assimetria Facial/cirurgia
9.
Med Oral Patol Oral Cir Bucal ; 27(2): e159-e163, 2022 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-35218644

RESUMO

BACKGROUND: The aim of this study is to investigate the presence of condylar and ramal asymmetry in patients with a cyst larger than 10 mm in the maxilla or mandible. MATERIAL AND METHODS: Condylar and ramal asymmetry index measurements of 47 patients (mean age: 28.85 ± 15.348) in the study group and 40 patients in the control group (mean age: 33.73 ± 13.095) were performed using panoramic radiographs. The study group consists of patients with cysts larger than 10 mm in diameter in the maxilla or mandible. The control group consisted of patients with no radiolucent lesions and no history of trauma. The possible statistical difference between the groups was evaluated by the Mann-Whitney U test. RESULTS: No statistically significant difference was observed in asymmetry indices according to gender and the jaw (maxilla or mandible) in which the cyst was located. However, it was determined that CAI and RAI values were statistically significantly different between the study and control groups (p = 0.047 and p = 0.016, respectively). CONCLUSIONS: The presence of intraosseous cysts larger than 10 mm in the jaws was found to be associated with condylar and ramal asymmetry.


Assuntos
Assimetria Facial , Côndilo Mandibular , Adolescente , Adulto , Cefalometria , Assimetria Facial/complicações , Assimetria Facial/patologia , Humanos , Mandíbula/patologia , Côndilo Mandibular/diagnóstico por imagem , Pessoa de Meia-Idade , Radiografia Panorâmica , Adulto Jovem
10.
J Clin Res Pediatr Endocrinol ; 12(3): 319-328, 2020 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-31782289

RESUMO

A novel heterozygous IVS11-2A>C(c.1957-2A>C) mutation in the GLI2 gene is reported. There was an extremely distinct phenotypical expression in two siblings and their father. The index case was a boy who developed cholestasis and hypoglycaemia in the neonatal period. He had bilateral postaxial polydactyly, mid-facial hypoplasia, high palatal arch, micropenis, and bilateral cryptorchidism. Laboratory examination revealed a diagnosis of multiple pituitary hormone deficiency. There was severe anterior pituitary hypoplasia, absent pituitary stalk and ectopic posterior pituitary on magnetic resonance imaging which suggested pituitary stalk interruption syndrome with no other midline structural abnormality. Molecular genetic analysis revealed a novel heterozygous splicing IVS11-2A>C(c.1957-2A>C) mutation detected in the GLI2 gene. His father and a six-year-old brother with the identical mutation also had unilateral postaxial polydactyly and mid-facial hypoplasia although there was no pituitary hormone deficiency. This novel heterozygous GLI2 mutation detected appears to present with an extremely variable clinical phenotype, even in related individuals with an identical mutation, suggesting incomplete penetrance of this GLI2 mutation.


Assuntos
Anormalidades Múltiplas/genética , Hipopituitarismo/genética , Proteínas Nucleares/genética , Proteína Gli2 com Dedos de Zinco/genética , Anormalidades Múltiplas/diagnóstico , Adulto , Encefalopatias/complicações , Encefalopatias/diagnóstico , Encefalopatias/genética , Criança , Coristoma/complicações , Coristoma/genética , Análise Mutacional de DNA , Assimetria Facial/complicações , Assimetria Facial/diagnóstico , Assimetria Facial/genética , Pai , Dedos/anormalidades , Heterozigoto , Humanos , Hipopituitarismo/complicações , Hipopituitarismo/diagnóstico , Lactente , Masculino , Mutação , Linhagem , Neuro-Hipófise/anormalidades , Neuro-Hipófise/patologia , Polidactilia/complicações , Polidactilia/diagnóstico , Polidactilia/genética , Inversão de Sequência , Irmãos , Dedos do Pé/anormalidades
11.
Fisioter. Pesqui. (Online) ; 26(2): 178-184, abr.-jun. 2019. tab, graf
Artigo em Português | LILACS | ID: biblio-1012135

RESUMO

RESUMO O objetivo deste estudo foi identificar se existe correlação entre a severidade da disfunção temporomandibular (DTM) e postura corporal, bem como evidenciar as diferenças existentes na postura corporal nos diferentes graus de severidade. Foram avaliadas 71 mulheres de 18 a 35 anos quanto à severidade da DTM e à postura corporal, sendo divididas em grupo sem DTM e grupo com DTM. Foram utilizados o questionário Mandibular Function Impairment Questionnaire e o software Digital Image-Based Postural Assessment de avaliação postural por fotogrametria. Foi realizada análise estatística com ANOVA de um fator e teste de correlação Tau B de Kendall (α<0,05). Os grupos com e sem DTM apresentaram diferenças estatísticas, com tamanho de efeito grande (ŋ2>0,528), para: lordose cervical, pulsão e inclinação da pelve. Quanto à correlação da postura com a severidade da DTM, índices fracos, mas significativos, foram encontrados: ângulo da lordose cervical (τ=0,250), ângulo da cifose dorsal (τ=0,192), ângulo de inclinação pélvica (τ=−0,222) e medida de pulsão da pelve (τ=0,283). Esses resultados indicam que a lordose cervical e a pulsão da pelve se apresentam em aumento da lordose e da pulsão conforme o acréscimo da severidade da DTM, enquanto o ângulo de inclinação se apresenta em menor grau, tendendo à retroversão. Apesar das correlações fracas, os resultados evidenciam alguma relação da postura corporal com a DTM.


RESUMEN El objetivo de este estudio fue identificar si existe una correlación entre la gravedad de la disfunción temporomandibular (DTM) y la postura corporal, así como mostrar las diferencias en la postura corporal en diferentes grados de gravedad. Se evaluó la la postura corporal de 71 mujeres de 18 a 35 años, divididas en dos grupos: sin DTM y con DTM. Se utilizó el cuestionario Mandibular Function Impairment Questionnaire y el software Digital Image-Based Postural Assessment de evaluación postural por fotogrametría. Se realizó análisis estadístico con Anova de un factor y prueba de correlación Tau B de Kendall (α<0,05). Los grupos con y sin DTM presentaron diferencias estadísticas, con tamaño de efecto grande (ŋ2>0,528) para: lordosis cervical, pulsión e inclinación de la pelvis. En cuanto a la correlación de la postura con la gravedad de la DTM, índices débiles pero significativos fueron encontrados: ángulo de la lordosis cervical (τ=0,250), ángulo de la cifosis dorsal (τ=0,192), ángulo de inclinación pélvica (τ=−0,222) y medida de pulsión de la pelvis (τ=0,283). Estos resultados indican que la lordosis cervical y la pulsión de la pelvis aumentan según la gravedad de la DTM, mientras que el ángulo de inclinación se presenta en menor grado, tendiendo a la retroversión. A pesar de las correlaciones débiles, los resultados evidencian cierta relación de la postura corporal con la DTM.


ABSTRACT This study aimed to identify if there is a correlation between temporomandibular dysfunction (TMD) severity and body posture, as well as to show the differences in body posture in different degrees of severity. Seventy-one women aged 18-35 years were assessed for TMD severity and body posture and were divided into: Group without TMD and Group with TMD. We used the Mandibular Function Impairment Questionnaire and the Digital Image-Based Postural Assessment software for postural evaluation by photogrammetry. Statistical analysis was performed with one-way ANOVA and Kendall's Tau B correlation test (α<0.05). The groups with and without TMD presented statistical differences, with large effect size (ŋ2>0.528), for: cervical lordosis, drive and pelvic tilt. Regarding the correlation of posture with TMD severity, weak but significant indexes were found: cervical lordosis angle (τ=0.250), dorsal kyphosis angle (τ=0.192), pelvic tilt angle (τ=−0.222) and pelvic drive measurement (τ=0.283). These results indicate that cervical lordosis and pelvic drive are increased according to the severity of the TMD, while the pelvic tilt angle decreases, tending to a retroversion. Despite the weak correlations, the results show some relationship between body posture and TMD.


Assuntos
Humanos , Feminino , Adulto , Postura/fisiologia , Síndrome da Disfunção da Articulação Temporomandibular/complicações , Curvaturas da Coluna Vertebral/complicações , Índice de Gravidade de Doença , Fotogrametria , Assimetria Facial/complicações , Cifose/complicações , Lordose/complicações
12.
Shanghai Kou Qiang Yi Xue ; 27(4): 376-381, 2018 Aug.
Artigo em Chinês | MEDLINE | ID: mdl-30483704

RESUMO

PURPOSE: The purpose of this study was to investigate the dental and craniofacial morphological characteristics in patients with mild skeletal facial asymmetry, and to investigate the relationship between mild skeletal facial asymmetry and dental anomalies. METHODS: Thirty patients with mild skeletal facial asymmetry (experimental group) and 30 patients with normal faces (control group) were selected. All patients were scanned by cone-beam computed tomography (CBCT) and X-ray machine, Winceph software was used to measure the posteroanterior cephalometric radiographs, NNT software was used to measure the CBCT data. The results were analyzed by Chi-square test, paired t test and independent sample t test using SPSS 19.0 software package. RESULTS: There were significant differences between the left and right sides of faces, teeth and alveolar bone of the first molar in the experimental group. The angle of mandibular dental midline and facial midline, the inclination of the frontal mandibular plane, the inclination of the first molar, the inclination of alveolar bone of the mandibular first molar, the width of alveolar bone of the mandibular first molar showed significant differences between the experimental group and the control group (P<0.05). There are some correlations among menton deviation, inclination of the first molar and alveolar bone of the first molar. CONCLUSIONS: Patients with mild skeletal facial asymmetry showed some specific skeletal and dental characteristics. There could be some correlations between these features..


Assuntos
Cefalometria , Assimetria Facial , Mandíbula , Anormalidades Dentárias , Tomografia Computadorizada de Feixe Cônico , Assimetria Facial/complicações , Humanos , Mandíbula/anormalidades , Dente Molar , Dente
13.
Orthod Fr ; 89(2): 199-212, 2018 06.
Artigo em Francês | MEDLINE | ID: mdl-30040619

RESUMO

INTRODUCTION: Clinical measurements in the frontal view underevaluate chin deviation in mandibular asymmetry. The aim of this descriptive study is to search for a reliable method of measuring deviant chins using a facial X-ray as reference. MATERIAL AND METHOD: Seventy patients with mandibular asymmetry who had consulted a maxillofacial surgeon were systematically included. Age, sex, cephalometric characteristics, reasons for patient consultation and type of surgery were collected. Two cephalometric methods were tested with respect to the medial sagittal plane (PSM) to compare the assessment of mandibular asymmetry on soft tissue and by cephalometry. RESULTS: On average, the patients selected were young (26 years +/- 9), women (75% of cases), presented open bite (average FMA: 28° +/- 8°), a skeletal class III tendency, a left-side shift of the chin (63% of cases). They consulted for both aesthetic and functional reasons (51% of cases) and required bimaxillary surgery (66% of cases). Comparison between the photographic angle (formed by the PSM and the line passing through the nasion and reaching the chin point) and the radiographic angle (formed by the PSM and the line passing through the Crista Galli process and the bony chin point angle) showed no significant difference (p = 0.937) and is thus reliable.


Assuntos
Cefalometria/métodos , Assimetria Facial/diagnóstico , Má Oclusão/diagnóstico , Mandíbula/anormalidades , Adolescente , Adulto , Queixo , Assimetria Facial/complicações , Assimetria Facial/patologia , Assimetria Facial/cirurgia , Feminino , Humanos , Masculino , Má Oclusão/epidemiologia , Má Oclusão/etiologia , Má Oclusão/cirurgia , Má Oclusão Classe III de Angle/diagnóstico , Má Oclusão Classe III de Angle/epidemiologia , Má Oclusão Classe III de Angle/etiologia , Má Oclusão Classe III de Angle/cirurgia , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Mandíbula/cirurgia , Procedimentos Cirúrgicos Ortognáticos/métodos , Fotografação/métodos , Reprodutibilidade dos Testes , Estudos Retrospectivos , Pele , Adulto Jovem
14.
Rev. bras. cir. plást ; 33(2): 258-261, abr.-jun. 2018. ilus
Artigo em Inglês, Português | LILACS | ID: biblio-909428

RESUMO

Síndrome do choro assimétrico é uma condição congênita secundária à hipoplasia ou ausência do músculo depressor do ângulo da boca. Trata-se de uma condição não tão incomum que pode cursar com assimetria facial ao chorar e sorrir, além de poder estar associadas a outras malformações congênitas. Crianças com essa deformidade podem sofrer dificuldades psicossociais e introversão. O arsenal terapêutico dessa condição já foi estudado e discutido na literatura com ênfase em abordagens cirúrgicas e invasivas. Relatamos aqui um caso de uma criança de 9 anos com essa síndrome, tratada, de forma menos invasiva, com toxina botulínica, com um bom resultado e satisfação.


Asymmetric crying face syndrome is a congenital condition secondary to hypoplasia or absence of the depressor muscle at the mouth angle. It is a common condition that presents with facial asymmetry while crying and smiling and may be associated with other congenital malformations. Children with this deformity may experience psychosocial difficulties and introversion. The therapeutic arsenal of this condition has already been studied and discussed in the literature with an emphasis on surgical and invasive approaches. We report here a case of a 9-year-old child with this syndrome, treated less invasively with botulinum toxin, with good result and satisfaction.


Assuntos
Humanos , Feminino , Criança , História do Século XXI , Anormalidades Congênitas , Toxinas Botulínicas Tipo A , Assimetria Facial , Paralisia Facial , Anormalidades da Boca , Anormalidades Congênitas/genética , Anormalidades Congênitas/reabilitação , Toxinas Botulínicas Tipo A/efeitos adversos , Toxinas Botulínicas Tipo A/efeitos dos fármacos , Toxinas Botulínicas Tipo A/farmacologia , Assimetria Facial/cirurgia , Assimetria Facial/complicações , Assimetria Facial/tratamento farmacológico , Paralisia Facial/cirurgia , Paralisia Facial/complicações , Paralisia Facial/congênito , Anormalidades da Boca/cirurgia , Anormalidades da Boca/diagnóstico , Anormalidades da Boca/reabilitação
15.
J Craniomaxillofac Surg ; 46(1): 28-34, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29221913

RESUMO

PURPOSE: The recommendation issued by the American Academy of Pediatrics in the early 1990s to position infants on their back during sleep to prevent sudden infant death syndrome (SIDS) has dramatically reduced the number of deaths due to SIDS but has also markedly increased the prevalence of positional skull deformation in infants. Deformation of the base of the skull occurs predominantly in very severe deformational plagiocephaly and is accompanied by facial asymmetry, as well as an altered ear position, called ear shift. Moulded helmet therapy has become an accepted treatment strategy for infants with deformational plagiocephaly. The aim of this study was to determine whether facial asymmetry could be corrected by moulded helmet therapy. MATERIALS AND METHODS: In this retrospective, single-centre study, we analysed facial asymmetry of 71 infants with severe deformational plagiocephaly with or without deformational brachycephaly who were undergoing moulded helmet therapy between 2009 and 2013. Computer-assisted, three-dimensional, soft-tissue photographic scanning was used to record the head shape before and after moulded helmet therapy. The distance between two landmarks in the midline of the face (i.e., root of the nose and nasal septum) and the right and left tragus were measured on computer-generated indirect and objective 3D photogrammetry images. A quotient was calculated between the two right- and left-sided distances to the midline. Quotients were compared before and after moulded helmet therapy. Infants without any therapy served as a control group. RESULTS: The median age of the infants before onset of moulded helmet therapy was 5 months (range 3-16 months). The median duration of moulded helmet therapy was 5 months (range 1-16 months). Comparison of the pre- and post-treatment quotients of the left vs. right distances measured between the tragus and root of the nose (n = 71) and nasal septum (n = 71) revealed a significant reduction of the asymmetry (Tragus-Nasion-Line Quotient: 0.045-0.022; p < 0.0001; Tragus-Subnasale-Line Quotient: 0.045-0.021; p < 0.0001). The control group without treatment showed no significant change in the quotient (Tragus-Nasion-Line Quotient no helmet: 0.049-0.055/Tragus-Subnasale-Line Quotient no helmet: 0.039-0.055). CONCLUSION: Moulded helmet therapy can correct facial symmetry in infants with deformational plagiocephaly and associated facial and basal skull asymmetry.


Assuntos
Assimetria Facial/complicações , Assimetria Facial/terapia , Plagiocefalia não Sinostótica/complicações , Feminino , Dispositivos de Proteção da Cabeça , Humanos , Lactente , Masculino , Estudos Retrospectivos , Terapêutica/instrumentação
16.
Am J Orthod Dentofacial Orthop ; 152(5): 631-645, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29103441

RESUMO

INTRODUCTION: We investigated whether ACTN3, ENPP1, ESR1, PITX1, and PITX2 genes which contribute to sagittal and vertical malocclusions also contribute to facial asymmetries and temporomandibular disorders (TMD) before and after orthodontic and orthognathic surgery treatment. METHODS: One hundred seventy-four patients with a dentofacial deformity were diagnosed as symmetric or subdivided into 4 asymmetric groups according to posteroanterior cephalometric measurements. TMD examination diagnosis and jaw pain and function (JPF) questionnaires assessed the presence and severity of TMD. RESULTS: Fifty-two percent of the patients were symmetric, and 48% were asymmetric. The asymmetry classification demonstrated significant cephalometric differences between the symmetric and asymmetric groups, and across the 4 asymmetric subtypes: group 1, mandibular body asymmetry; group 2, ramus asymmetry; group 3, atypical asymmetry; and group 4, C-shaped asymmetry. ENPP1 SNP-rs6569759 was associated with group 1 (P = 0.004), and rs858339 was associated with group 3 (P = 0.002). ESR1 SNP-rs164321 was associated with group 4 (P = 0.019). These results were confirmed by principal component analysis that showed 3 principal components explaining almost 80% of the variations in the studied groups. Principal components 1 and 2 were associated with ESR1 SNP-rs3020318 (P <0.05). Diagnoses of disc displacement with reduction, masticatory muscle myalgia, and arthralgia were highly prevalent in the asymmetry groups, and all had strong statistical associations with ENPP1 rs858339. The average JPF scores for asymmetric subjects before surgery (JPF, 7) were significantly higher than for symmetric subjects (JPF, 2). Patients in group 3 had the highest preoperative JPF scores, and groups 2 and 3 were most likely to be cured of TMD 1 year after treatment. CONCLUSIONS: Posteroanterior cephalometrics can classify asymmetry into distinct groups and identify the probability of TMD and genotype associations. Orthodontic and orthognathic treatments of facial asymmetry are effective at eliminating TMD in most patients.


Assuntos
Deformidades Dentofaciais/classificação , Deformidades Dentofaciais/genética , Receptor alfa de Estrogênio/genética , Assimetria Facial/classificação , Assimetria Facial/genética , Diester Fosfórico Hidrolases/genética , Pirofosfatases/genética , Transtornos da Articulação Temporomandibular/genética , Adulto , Deformidades Dentofaciais/complicações , Deformidades Dentofaciais/cirurgia , Assimetria Facial/complicações , Assimetria Facial/cirurgia , Feminino , Genótipo , Humanos , Masculino , Procedimentos Cirúrgicos Ortognáticos , Complicações Pós-Operatórias/etiologia , Índice de Gravidade de Doença , Transtornos da Articulação Temporomandibular/etiologia
17.
Am J Orthod Dentofacial Orthop ; 152(5): 679-692, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29103446

RESUMO

This article describes the complex dental treatment of a 43-year-old man with skeletal Class II, mandibular asymmetry, severe brachyfacial pattern, Class II Division 2, canting of the occlusal plane, and an increased curve of Spee. To achieve optimal results, we adopted a multidisciplinary approach to treatment, involving periodontics, oral surgery, orthodontics, maxillofacial surgery, and prosthetics specialists. After periodontal treatment, miniscrews were placed to correct the occlusal plane canting and the excessive curve of Spee with orthodontic treatment. The surgical treatment plan consisted of a bilateral asymmetric sagittal split osteotomy for mandibular advancement and genioplasty. The patient had an infection after the surgery at the site of the right fixation plate, so the plate was removed, and active orthodontic treatment was continued and finished. Mandibular first molar implants and maxillary ceramic crowns using the Digital Smile Design method (Digital Smile Design, Doral, FL) were placed at the end of orthodontic treatment. The patient was satisfied with the treatment results and with his facial and dental appearance, as well as his oral function. The 2-year follow-up pictures show a stable result both esthetically and functionally.


Assuntos
Parafusos Ósseos , Assimetria Facial/cirurgia , Mentoplastia , Má Oclusão Classe II de Angle/cirurgia , Mandíbula/anormalidades , Mandíbula/cirurgia , Avanço Mandibular , Ortodontia Corretiva , Adulto , Terapia Combinada , Assimetria Facial/complicações , Humanos , Masculino , Má Oclusão Classe II de Angle/complicações
18.
Dental press j. orthod. (Impr.) ; 22(6): 86-98, Nov.-Dec. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-891110

RESUMO

ABSTRACT Skeletal Class III malocclusions are ideally treated with orthodontic-surgical approaches. However, if there are no significant soft tissue implications and the patient does not want to undergo orthognatic surgery, other treatment options may be considered. The current case report describes a compensatory alternative for Class III malocclusion treatment, by means of mandibular canine extractions. This treatment alternative provided facial profile and occlusal improvement, which remains stable seven years posttreatment.


RESUMO As más oclusões esqueléticas de Classe III são idealmente tratadas com intervenções ortodôntico-cirúrgicas. Contudo, se não existirem implicações estéticas faciais e se o paciente não desejar se submeter à cirurgia ortognática, outras opções de tratamento podem ser consideradas. O presente caso clínico descreve um tratamento compensatório alternativo para a má oclusão de Classe III, com extrações de caninos inferiores. Esse tratamento alternativo propiciou melhoras no perfil facial e na oclusão, que permaneceu estável após sete anos da sua finalização.


Assuntos
Humanos , Feminino , Adolescente , Ortodontia Corretiva/métodos , Extração Dentária , Dente Canino/cirurgia , Má Oclusão Classe III de Angle/cirurgia , Má Oclusão Classe III de Angle/terapia , Mandíbula/cirurgia , Ortodontia Corretiva/instrumentação , Planejamento de Assistência ao Paciente , Radiografia Panorâmica , Cefalometria , Técnica de Fundição Odontológica , Técnica de Expansão Palatina , Resultado do Tratamento , Braquetes Ortodônticos , Aparelhos de Tração Extrabucal , Assimetria Facial/complicações , Assimetria Facial/terapia , Má Oclusão Classe III de Angle/diagnóstico por imagem , Mandíbula/diagnóstico por imagem
19.
Am J Orthod Dentofacial Orthop ; 152(2): 268-280, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28760289

RESUMO

Our objective was to report the orthodontic and surgical retreatment of a patient who had undergone a prolonged orthodontic treatment with extractions, but who had unsatisfactory results and persistent side effects. The man, aged 25 years 3 months, sought treatment with major complaints of facial and smile asymmetries. The clinical examination showed a mandibular deviation to the right and a maxillary occlusal cant. A Class II Division 1 subdivision right was observed. Radiographic examination showed extensive root resorptions in the maxillary second premolars and absence of the 4 first premolars. The maxillary midline was deflected 2 mm to the left, and the mandibular midline was shifted 5 mm to the right. Aligning and leveling were performed with orthodontic fixed appliances, with a standard edgewise system (0.022 × 0.028 in), followed by LeFort I maxillary impaction and bilateral sagittal split osteotomy with asymmetrical advancement. Retreatment showed outstanding results that remained stable after 3 years of follow-up. Root resorption in the second premolars did not seem to increase. Orthodontic-surgical intervention is the main choice for correcting esthetic and functional problems in facial asymmetry, particularly in cases of retreatment.


Assuntos
Assimetria Facial/cirurgia , Má Oclusão Classe II de Angle/cirurgia , Procedimentos Cirúrgicos Ortognáticos/métodos , Reabsorção da Raiz/cirurgia , Adulto , Assimetria Facial/complicações , Assimetria Facial/diagnóstico por imagem , Seguimentos , Humanos , Masculino , Má Oclusão Classe II de Angle/complicações , Má Oclusão Classe II de Angle/diagnóstico por imagem , Radiografia Dentária , Radiografia Panorâmica , Reoperação , Reabsorção da Raiz/complicações , Reabsorção da Raiz/diagnóstico por imagem
20.
Am J Orthod Dentofacial Orthop ; 152(2): 255-267, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28760288

RESUMO

This case report describes a surgical orthodontic case that used the recently introduced surgery-first approach to correct a severe skeletal Class III malocclusion. A 19-year-old woman presented with severe mandibular prognathism and facial asymmetry; she had been waiting for growth completion in order to pursue surgical correction. After prediction of the postsurgical tooth movement and surgical simulation, 2-jaw surgery that included maxillary advancement and differential mandibular setback was performed using a surgery-first approach. Immediate facial improvement was achieved and postsurgical orthodontic treatment was efficiently carried out. The total treatment time was 16 months. The patient's facial appearance improved significantly and a stable surgical orthodontic outcome was obtained.


Assuntos
Assimetria Facial/complicações , Má Oclusão Classe III de Angle/cirurgia , Mandíbula/anormalidades , Adulto , Tomografia Computadorizada de Feixe Cônico , Assimetria Facial/diagnóstico por imagem , Assimetria Facial/cirurgia , Feminino , Humanos , Má Oclusão Classe III de Angle/complicações , Má Oclusão Classe III de Angle/diagnóstico por imagem , Mandíbula/diagnóstico por imagem , Mandíbula/cirurgia , Radiografia Panorâmica
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