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1.
Rev. Bras. Saúde Mater. Infant. (Online) ; 21(2): 667-671, Apr.-June 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1340653

RESUMO

Abstract Introduction: the avulsion of primary teeth is a disturbing and unexpected event. Description: this report describes the clinical case of a three-year-old child who suffered an avulsion and replantation of the primary upper central incisors at the site of the injury. The guardians sought treatment for the child at the Federal University of Minas Gerais after the replantation. Four months later, the child suffered a new trauma and the replanted teeth presented advanced mobility, root resorption and fistula. The clinical conduct was extraction and rehabilitation with a fixed esthetic maintainer. Discussion: the literature describes two treatment options for avulsion of primary incisors: replantation and non-replantation. According to a recent systematic review, the difficulty in obtaining a consensus regarding the best clinical conduct is due, in part, to the scarcity of publications that present not only follow-ups with clinical success, but also with failures. The outcomes of replantation can be influenced by several factors. The time elapsed between replantation and splinting, and the new episode of trauma, negatively influenced the prognosis in the present case, leading to failure. Replantation of primary incisors is not yet evidence-based treatment. Therefore, this option must be chosen with caution and in ideal situations. It requires constant clinical and radiographic monitoring for evaluation of outcomes.


Resumo Introdução: a avulsão de dentes decíduos é um evento perturbador e inesperado. Descrição: o presente relato descreve o caso clínico de uma criança de três anos que sofreu avulsão e reimplante dos incisivos centrais superiores decíduos no local do acidente. Os responsáveis procuraram atendimento para a criança na Universidade Federal de Minas Gerais após reimplante. Quatro meses depois, a criança sofreu novo trauma e os dentes reimplantados apresentavam mobilidade avançada, reabsorção radicular e fístula. A conduta clínica foi extração e reabilitação com mantenedor estético fixo. Discussão: a literatura descreve duas opções de tratamento para avulsão de incisivos decíduos: o reimplante e o não reimplante. De acordo com revisão sistemática recente, a dificuldade de se obter um consenso sobre a melhor conduta clínica se deve, em parte, à escassez de publicações que apresentem não apenas acompanhamentos com sucesso clínico, mas também com falhas. O reimplante pode ser influenciado por vários fatores. O tempo decorrido entre o reimplante e a contenção, e o novo episódio de trauma, influenciaram negativamente o prognóstico do presente caso, levando ao insucesso. O reimplante de incisivos decí- duos ainda não é um tratamento baseado em evidências. Portanto, essa opção deve ser escolhida com cautela e em situações ideais. Requer monitoramento clínico e radiográfico para constante avaliação do desfecho.


Assuntos
Humanos , Pré-Escolar , Dente Decíduo/cirurgia , Dente Decíduo/lesões , Avulsão Dentária/terapia , Reimplante Dentário/efeitos adversos , Reimplante Dentário/métodos
2.
Anticancer Res ; 41(4): 2083-2092, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33813418

RESUMO

BACKGROUND/AIM: Numerical aberrations of permanent dentition and dystopic tooth eruption are part of the phenotype of the tumor predisposition syndrome neurofibromatosis type 1 (NF1). In these cases, surplus tooth germs usually develop in the alveolar processes of the jaw. This report attests to the dystopic development of a dysplastic supernumerary tooth in NF1 arising outside the jaw. CASE REPORT: The 8-year-old male patient developed a microdont outside the bone and above the occlusal plane of the retained maxillary right second molar. The supernumerary tooth was completely embedded in oral soft tissue. Hyperplastic oral soft tissue in the molar region and microdont were excised. Specimen of the mucosa surrounding the teeth was interspersed with diffuse and plexiform neurofibroma. The retained upper right first molar emerged spontaneously within a few months after surgery. The upper right second molar did not change position. CONCLUSION: Odontogenesis can take place within tumorous oral mucosa in NF1. Surgical removal of the tumorous mucous membrane facilitates tooth eruption in some cases.


Assuntos
Processo Alveolar/patologia , Neoplasias Bucais/diagnóstico , Neurofibroma Plexiforme/diagnóstico , Neurofibromatose 1/diagnóstico , Erupção Ectópica de Dente/diagnóstico , Processo Alveolar/anormalidades , Processo Alveolar/diagnóstico por imagem , Processo Alveolar/cirurgia , Criança , Humanos , Masculino , Neoplasias Bucais/complicações , Neoplasias Bucais/patologia , Neoplasias Bucais/cirurgia , Neurofibroma Plexiforme/complicações , Neurofibroma Plexiforme/patologia , Neurofibroma Plexiforme/cirurgia , Neurofibromatose 1/complicações , Neurofibromatose 1/patologia , Neurofibromatose 1/cirurgia , Anormalidades Dentárias/diagnóstico , Anormalidades Dentárias/etiologia , Anormalidades Dentárias/patologia , Anormalidades Dentárias/cirurgia , Erupção Ectópica de Dente/etiologia , Erupção Ectópica de Dente/cirurgia , Dente Decíduo/anormalidades , Dente Decíduo/diagnóstico por imagem , Dente Decíduo/patologia , Dente Decíduo/cirurgia , Dente Supranumerário/diagnóstico , Dente Supranumerário/etiologia , Dente Supranumerário/patologia , Dente Supranumerário/cirurgia
3.
Sci Rep ; 11(1): 3859, 2021 02 16.
Artigo em Inglês | MEDLINE | ID: mdl-33594151

RESUMO

This study aimed to assess the apical extrusion of debris during instrumentation of primary canines using three endodontic file types. Forty-five extracted primary canines were randomly assigned to three instrumentation groups (n = 15): Hand K-files; and the motorized Kedo-S files and XP-endo Shaper files. The apically extruded debris produced during the procedure was collected and dried in pre-weighed Eppendorf tubes, and the mass of debris was calculated. The time required for the endodontic procedure was also recorded. Analysis of variance (ANOVA) and Tukey's post hoc test were used with a significance level set at 5%. XP-endo Shaper and Kedo-S files extruded significantly less debris compared with hand K-files with means of 0.84 ± 0.31 and 1.20 ± 0.67 mg respectively, compared to 2.13 ± 0.31 mg (p < 0.0001). No significant difference was found between the two motorized files. Less time was required to complete the procedure with the XP-endo Shaper compared to the hand K-files (p < 0.0001) and Kedo-S files (p < 0.0001). Within the limitations of the present study, it may be concluded that motorized files extruded less debris and required less instrumentation time compared to traditional K-files, which could benefit paediatric patients with root canal treatment needs.


Assuntos
Tratamento do Canal Radicular/instrumentação , Dente Decíduo/cirurgia , Humanos , Duração da Cirurgia , Distribuição Aleatória , Tratamento do Canal Radicular/estatística & dados numéricos
4.
Rev. Cient. CRO-RJ (Online) ; 5(2): 65-68, May-Aug. 2020.
Artigo em Inglês | BBO - Odontologia, LILACS | ID: biblio-1254134

RESUMO

Introduction: Studies of twins are important because environmental and genetic factors seem to be related to the phenotypic alterations. Objective: This paper presents a unique case of monozygotic twins with mirror image of a retained primary central incisor. Case report: Twin male brothers, 9-years-old, presented prolonged retention of the primary central upper incisor. The over-retained teeth in one twin were a mirror image of those in the other twin. The first twin presented a prolonged retention of the tooth 51 whereas the other twin presented a prolonged retention of tooth 61. After radiographic exams the over-retained teeth were extracted. Conclusion: Twins may show similarity in pattern of dental anomalies supporting the influence of genetic factors. In identical twins the location of diagnosed anomalies can be mirror imaged. This fact should lead the professional to examine the pair of twins in order to diagnose any dental anomaly that may be present.


Introdução: Estudos feitos em gêmeos são importantes porque fatores ambientais e genéticos parecem estar relacionados às alterações fenotípicas. Objetivo: Este artigo apresenta um caso raro de gêmeos monozigóticos apresentando imagem em espelho de retenção prolongada de incisivos centrais decíduos superiores homólogos. Relato do caso: Os irmãos gêmeos, com 9 anos de idade, não apresentavam história de trauma orofacial ou doença comum da infância. Após exames clínicos e radiográficos foram identificados a retenção do dente 51 no gêmeo 1 e do dente 61 no gêmeo 2. Em ambos os pacientes, os dentes 11 e o 21 estavam em erupção. O tratamento proposto foi a exodontia dos dentes decíduos com anestesia local e acompanhamento. Conclusão: Gêmeos podem apresentar semelhança no padrão de anomalias dentárias devido à influência de fatores genéticos. Adicionalmente, em gêmeos monozigóticos, a localização das anomalias diagnosticadas pode se apresentar invertidas ou imagem em espelho. Esse fato deve estimular o profissional a examinar o par de gêmeos para diagnosticar qualquer anomalia dentária que possa estar presente. O diagnóstico precoce e tratamento adequados devem ser realizados para evitar danos funcionais e estéticos em pacientes com retenções dentárias.


Assuntos
Humanos , Masculino , Criança , Dente Decíduo/diagnóstico por imagem , Dente não Erupcionado/diagnóstico por imagem , Gêmeos Monozigóticos , Incisivo/anormalidades , Dente Decíduo/cirurgia , Extração Dentária , Dente não Erupcionado/cirurgia
6.
Theranostics ; 9(9): 2694-2711, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31131062

RESUMO

A stem cell-mediated bioengineered tooth root (bio-root) has proven to be a prospective tool for the treatment of tooth loss. As shown in our previous studies, dental follicle cells (DFCs) are suitable seeding cells for the construction of bio-roots. However, the DFCs which can only be obtained from unerupted tooth germ are restricted. Stem cells from human exfoliated deciduous teeth (SHEDs), which are harvested much more easily through a minimally invasive procedure, may be used as an alternative seeding cell. In this case, we compared the odontogenic characteristics of DFCs and SHEDs in bio-root regeneration. Methods: The biological characteristics of SHEDs and DFCs were determined in vitro. The cells were then induced to secrete abundant extracellular matrix (ECM) and form macroscopic cell sheets. We combined the cell sheets with treated dentin matrix (TDM) for subcutaneous transplantation into nude mice and orthotopic jaw bone implantation in Sprague-Dawley rats to further verify their regenerative potential. Results: DFCs exhibited a higher proliferation rate and stronger osteogenesis and adipogenesis capacities, while SHEDs displayed increased migration ability and excellent neurogenic potential. Both dental follicle cell sheets (DFCSs) and sheets of stem cells from human exfoliated deciduous teeth (SHEDSs) expressed not only ECM proteins but also osteogenic and odontogenic proteins. Importantly, similar to DFCSs/TDM, SHEDSs/TDM also successfully achieved the in vivo regeneration of the periodontal tissues, which consist of periodontal ligament fibers, blood vessels and new born alveolar bone. Conclusions: Both SHEDs and DFCs possessed a similar odontogenic differentiation capacity in vivo, and SHEDs were regarded as a prospective seeding cell for use in bio-root regeneration in the future.


Assuntos
Terapia Baseada em Transplante de Células e Tecidos/métodos , Saco Dentário/citologia , Dentina/química , Osteogênese/fisiologia , Transplante de Células-Tronco/métodos , Raiz Dentária/citologia , Adolescente , Animais , Diferenciação Celular/efeitos dos fármacos , Proliferação de Células/efeitos dos fármacos , Criança , Coristoma , Misturas Complexas/farmacologia , Saco Dentário/efeitos dos fármacos , Saco Dentário/fisiologia , Matriz Extracelular/metabolismo , Feminino , Humanos , Masculino , Camundongos , Camundongos Nus , Osteogênese/efeitos dos fármacos , Ligamento Periodontal/citologia , Ligamento Periodontal/efeitos dos fármacos , Ligamento Periodontal/fisiologia , Cultura Primária de Células , Ratos , Ratos Sprague-Dawley , Regeneração/efeitos dos fármacos , Regeneração/fisiologia , Células-Tronco/citologia , Células-Tronco/efeitos dos fármacos , Células-Tronco/fisiologia , Técnicas de Cultura de Tecidos , Raiz Dentária/fisiologia , Raiz Dentária/cirurgia , Dente Decíduo/citologia , Dente Decíduo/fisiologia , Dente Decíduo/cirurgia , Transplante Heterólogo , Adulto Jovem
7.
J Indian Soc Pedod Prev Dent ; 37(1): 75-79, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30804311

RESUMO

INTRODUCTION: Pulpectomy has been a treatment of choice in all necrotic primary teeth. Advancing technology has brought the rotary system to reduce the manual dexterity and improve the quality of treatment for pulpectomy. Advancing technology in pediatric dentistry should be used for the better treatment protocol. AIM: The aim of this study is to compare the obturation quality and instrumentation time after root canal instrumentation with rotary Kedo-S files, hand K-files, and H-files in primary molars. MATERIALS AND METHODS: A randomized control trial where pulpectomy was performed on 75 primary molars equally distributed for instrumentation with K-file, H-files rotary Kedo-S files, respectively. The instrumentation time and obturation quality were noted. RESULTS: Kedo-S files showed the least instrumentation time with better obturation quality as compared to other two groups (P < 0.001). CONCLUSION: Pediatric rotary files Kedo-S has better obturation quality in minimum instrumentation time.


Assuntos
Obturação do Canal Radicular/instrumentação , Criança , Pré-Escolar , Método Duplo-Cego , Feminino , Humanos , Masculino , Dente Molar/cirurgia , Duração da Cirurgia , Obturação do Canal Radicular/métodos , Obturação do Canal Radicular/normas , Dente Decíduo/cirurgia
8.
J. appl. oral sci ; 27: e20180030, 2019. tab, graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1002410

RESUMO

Abstract Objectives: To evaluate the effect of calcium hydroxide (CH) associated with two different vehicles as a capping material for pulp tissue in primary molars, compared with mineral trioxide aggregate (MTA). Methodology: Forty-five primary mandibular molars with dental caries were treated by conventional pulpotomy using one of the following materials: MTA only (MTA group), CH with saline (CH+saline group) and CH with polyethylene glycol (CH+PEG group) (15 teeth/group). Clinical and periapical radiographic examinations of the pulpotomized teeth were performed 3, 6, and 12 months after treatment. Data were tested by chi-squared analysis and a multiple comparison post-test. Results: The MTA group showed both clinical and radiographic treatment success in 14/14 teeth (100%), at all follow-up appointments. By clinical evaluation, no teeth in the CH+saline and CH+PEG groups had signs of mobility, fistula, swelling or inflammation of the surrounding gingival tissue. However, in the CH+saline group, radiographic analysis detected internal resorption in up to 9/15 teeth (67%), and inter-radicular bone resorption and furcation radiolucency in up to 5/15 teeth (36%), from 3 to 12 months of follow-up. In the CH+PEG group, 2/11 teeth (18%) had internal resorption and 1/11 teeth (9%) presented bone resorption and furcation radiolucency at all follow-up appointments. Conclusion: CH with PEG performed better than CH with saline as capping material for pulpotomy of primary teeth. However, both combinations yielded clinical and radiographic results inferior to those of MTA alone.


Assuntos
Humanos , Pré-Escolar , Criança , Óxidos/uso terapêutico , Pulpotomia/métodos , Dente Decíduo/cirurgia , Hidróxido de Cálcio/uso terapêutico , Silicatos/uso terapêutico , Compostos de Cálcio/uso terapêutico , Compostos de Alumínio/uso terapêutico , Agentes de Capeamento da Polpa Dentária e Pulpectomia/uso terapêutico , Fatores de Tempo , Dente Decíduo/diagnóstico por imagem , Hidróxido de Cálcio/química , Radiografia Dentária , Estudos Prospectivos , Seguimentos , Resultado do Tratamento , Combinação de Medicamentos , Agentes de Capeamento da Polpa Dentária e Pulpectomia/química , Solução Salina/uso terapêutico , Solução Salina/química
9.
Pediatr Dent ; 40(5): 334-339, 2018 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-30355428

RESUMO

Purpose: The purpose of this study was to compare the periodontal health and clinical success of restoring primary molars with a prefabricated stainless steel crown (SSC) or zirconia crown (ZC). Methods: Six- to nine-year-olds with at least two decayed primary molars were included. Teeth were restored with SSCs and ZCs. Intact contralateral primary molars were evaluated as controls. A simplified oral hygiene index (OHI-S), plaque index (PI), gingival index (GI), and clinical success criteria for the crowns were evaluated during follow-up. Friedman and Wilcoxon tests were used for statistical analysis. Results: Fifty-two teeth were evaluated in 13 children for 12 months. The OHI-S levels were not different at the follow-ups. Teeth restored with ZCs showed lower GI and PI scores than those restored with SSCs, even among controls. All SSCs were retained after 12 months, while two of the ZCs decemented. Minor staining in one ZC and a fracture on the surface of another ZC were observed. Conclusions: The gingival health and plaque accumulation performance of zirconia crowns were better than those of stainless steel crowns and controls. SSCs are highly retentive and viable restorative option, although they were associated with a decline in gingival health.


Assuntos
Coroas , Cárie Dentária/cirurgia , Materiais Dentários , Restauração Dentária Permanente , Aço Inoxidável , Dente Decíduo/cirurgia , Zircônio , Criança , Índice de Placa Dentária , Falha de Restauração Dentária , Estética Dentária , Feminino , Humanos , Masculino , Índice Periodontal , Estudos Prospectivos
10.
Dental Press J Orthod ; 23(4): 55-63, 2018 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-30304154

RESUMO

OBJECTIVE: The present article aims at reporting the clinical case of a patient who suffered trauma at two years of age, causing almost complete apical displacement of the deciduous maxillary left central incisor and of the permanent incisor. METHODS: Ectopia secondary to intrusion was minimized by surgical removal of the ectopic tooth, and the left permanent canine was submitted to orthodontic traction to replace the extracted tooth. RESULTS: The treatment period lasted 36 months, resulting in correct occlusion and a good aesthetic outcome. CONCLUSIONS: Dental transposition carried out by means of orthopedic traction is a good alternative in cases of a very unfavorable ectopic tooth position.


Assuntos
Dente Canino , Incisivo , Dente Decíduo/lesões , Anodontia , Criança , Estética Dentária , Feminino , Humanos , Incisivo/anormalidades , Maxila , Procedimentos Ortopédicos , Dente Decíduo/cirurgia , Tração
11.
J Indian Soc Pedod Prev Dent ; 36(3): 315-318, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30246756

RESUMO

Oral mucoceles are benign lesions that may appear in any location on the mucosal surfaces of the oral cavity where underlying minor salivary glands are found. The lower lip is the most frequently affected and the most widely reported location. Mucoceles involving the glands of Blandin and Nuhn are infrequent and constitute only about 1.9%-10.3% of the reported cases. Superficial mucoceles are a rare subtype of the Blandin and Nuhn mucoceles and are found only in 4.3%-10% of the mucocele excisions. The purpose of this report is to present a case of a superficial mucocele in the ventral surface of the tongue in a 7-year-old child. The lesion was treated with excisional biopsy.


Assuntos
Mucocele/patologia , Mucocele/cirurgia , Doenças da Língua/patologia , Doenças da Língua/cirurgia , Biópsia , Criança , Feminino , Humanos , Incisivo/cirurgia , Extração Dentária , Dente Decíduo/cirurgia
12.
Dental press j. orthod. (Impr.) ; 23(4): 55-63, July-Aug. 2018. graf
Artigo em Inglês | LILACS | ID: biblio-953038

RESUMO

ABSTRACT Objective: The present article aims at reporting the clinical case of a patient who suffered trauma at two years of age, causing almost complete apical displacement of the deciduous maxillary left central incisor and of the permanent incisor. Methods: Ectopia secondary to intrusion was minimized by surgical removal of the ectopic tooth, and the left permanent canine was submitted to orthodontic traction to replace the extracted tooth. Results: The treatment period lasted 36 months, resulting in correct occlusion and a good aesthetic outcome. Conclusions: Dental transposition carried out by means of orthopedic traction is a good alternative in cases of a very unfavorable ectopic tooth position.


RESUMO Objetivo: o presente relato de caso descreve uma paciente que sofreu trauma aos dois anos de idade, causando deslocamento apical quase completo do incisivo central esquerdo decíduo e do incisivo permanente. Métodos: a ectopia resultante da intrusão foi minimizada pela remoção cirúrgica do dente ectópico, e o canino permanente esquerdo foi tracionado ortodonticamente para substituir o dente extraído. Resultados: o período de tratamento durou 36 meses, obtendo-se uma oclusão correta e um bom resultado estético. Conclusões: a transposição dentária realizada através da tração ortopédica é uma boa alternativa em casos de dentes ectópicos em posições muito desfavoráveis.


Assuntos
Humanos , Feminino , Criança , Dente Decíduo/lesões , Dente Canino , Incisivo/anormalidades , Dente Decíduo/cirurgia , Tração , Procedimentos Ortopédicos , Estética Dentária , Maxila , Anodontia
13.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 53(5): 344-350, 2018 May 09.
Artigo em Chinês | MEDLINE | ID: mdl-29972994

RESUMO

Objective: To compare the influence of extraction and retention of the intruded dogs' teeth on permanent successors. Methods: Nine healthy 45-days-old Chinese rural puppies were selected, and six were submitted to the intrusion of the bilateral canine. Intruded teeth on the left side were extracted 30 minutes later and the teeth on the right side were kept in their sockets. After 8 months, all dogs were sacrificed. General observation, periapical radiograph and cone beam CT were used to observe the preoperative and postoperative deciduous teeth, permanent germs and permanent teeth development. The structure and content of successors' enamel were observed by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Results: In the extraction groups, the enamel hypoplasia was found in 19 permanent successors, ectopic eruption in 2 cases and abnormal teeth were in 19 cases in total (79%). In the retention groups, enamel hypoplasia of the permanent successors occurred in 2 cases, root dilaceration in 6 cases, and ectopic eruption in 5 cases, retained deciduous teeth in 3 cases, and there were 22 abnormal teeth in total (92%). In blank control group, there was no abnormal teeth. The major effect of intruded deciduous teeth on the permanent successors exhibited enamel hypoplasia [85% (41/48)], presented as enamel coloration and enamel defect (P=0.416). Conclusions: The intruded deciduous teeth should be removed early in order to reduce the effect on the permanent teeth.


Assuntos
Dentição Permanente , Anormalidades Dentárias/etiologia , Extração Dentária , Animais , Dente Canino , Assistência Odontológica , Esmalte Dentário/ultraestrutura , Hipoplasia do Esmalte Dentário/etiologia , Cães , Microscopia Eletrônica de Varredura , Radiografia Dentária , Erupção Dentária , Dente Decíduo/cirurgia
14.
Photochem Photobiol ; 94(6): 1240-1248, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-29923618

RESUMO

This study aimed to evaluate the use of antimicrobial photodynamic therapy (aPDT) as an adjunct for minimally invasive treatment (partial removal of carious tissue-PRCT) of deciduous carious tissue evaluating its efficacy in reducing microorganisms. For that, a clinical study was design including children with deciduous molars with active deep caries lesions (DCL). PRCT was performed and remaining dentin was treated with 100 µg mL-1 methylene blue solution (5 min) and than irradiated with a low power laser emitting red light (InGaAIP-indium gallium aluminum phosphide; λ = 660 nm; 100 mW; 300 J cm-2 ; 90 s; 9 J). The colony forming units (CFU) count after PRCT and after PRCT + aPDT/mg of dentin were compared for total microorganisms, including Candida spp., the mutans streptococci group, Streptococcus spp. and Lactobacillus spp. The dentin was classified (color, consistency and humidity). The microbial reduction varied from 69.88% to 86.29% and was significantly observed for total microorganisms, mutans streptococci, Streptococcus spp. and Lactobacillus spp (P < 0.001). The dentin type did not influence reduction of microorganisms (P > 0.05). The aPDT presents a promising future for clinical use as an adjunct for the reduction of microorganisms in PRCT of DCL in all kinds of dentin.


Assuntos
Cárie Dentária/tratamento farmacológico , Azul de Metileno/administração & dosagem , Dente Molar/efeitos dos fármacos , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/administração & dosagem , Dente Decíduo/efeitos dos fármacos , Candida/efeitos dos fármacos , Candida/crescimento & desenvolvimento , Criança , Pré-Escolar , Cárie Dentária/microbiologia , Cárie Dentária/cirurgia , Esmalte Dentário/efeitos dos fármacos , Esmalte Dentário/microbiologia , Esmalte Dentário/cirurgia , Dentina/efeitos dos fármacos , Dentina/microbiologia , Dentina/cirurgia , Feminino , Humanos , Lactobacillus/efeitos dos fármacos , Lactobacillus/crescimento & desenvolvimento , Lasers , Luz , Masculino , Azul de Metileno/metabolismo , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Dente Molar/microbiologia , Dente Molar/cirurgia , Fármacos Fotossensibilizantes/metabolismo , Streptococcus/efeitos dos fármacos , Streptococcus/crescimento & desenvolvimento , Dente Decíduo/microbiologia , Dente Decíduo/cirurgia , Resultado do Tratamento
15.
Braz. dent. j ; 29(2): 159-165, Mar.-Apr. 2018. graf
Artigo em Inglês | LILACS | ID: biblio-951525

RESUMO

Abstract The aim of this study was to evaluate the clinical, radiographic and histological outcomes of the dentin-pulp complex from primary molars after pulpotomy with mineral trioxide aggregate (MTA) and 15.5% ferric sulfate (FS). Thirty-one primary molars were randomly allocated into MTA or FS groups. Clinical and radiographic evaluations were recorded at 3-, 6-, 12- and 18-month follow-up. Teeth at the regular exfoliation period were extracted and processed for histological analysis. Clinical and radiographic data were tested by statistical analysis (p≤0.01). Histological outcomes were analyzed descriptively. All of the treated teeth presented clinical success over the experimental periods. Both groups exhibited 100% of radiographic success at 3, 6 and 12 months. At the 18-month follow-up, one tooth from FS group presented inter-radicular radiolucency (p>0.01). Histologically, the treated teeth presented pulp vitality and absence of inflammatory infiltrate into the connective tissue. Only MTA group showed hard tissue barrier surrounded by odontoblasts over the pulp stumps. Both MTA and 15.5% FS are effective for pulpotomies of primary teeth. Although MTA is considered the first-choice material, FS may be a suitable alternative when treatment cost is an issue.


Resumo O objetivo deste estudo foi avaliar os resultados clínicos, radiográficos e histológicos do complexo dentino-pulpar de molares decíduos após pulpotomia com agregado trióxido mineral (MTA) e sulfato férrico (SF) 15,5%. Trinta e um molares decíduos foram alocados aleatoriamente nos grupos MTA ou SF. As avaliações clínicas e radiográficas foram realizadas aos 3, 6, 12 e 18 meses de acompanhamento. Os dentes no período regular de esfoliação foram extraídos e processados ​​para análise histológica. Os dados clínicos e radiográficos foram analisados estatisticamente (p≤0,01). O resultados histológicos foram analisados ​​descritivamente. Todos os dentes tratados apresentaram sucesso clínico ao longo dos períodos experimentais. Ambos os grupos exibiram 100% de sucesso radiográfico aos 3, 6 e 12 meses. Aos 18 meses de acompanhamento, um dente do grupo SF apresentou radiolucidez interradicular (p>0,01). Histologicamente, os dentes tratados apresentaram vitalidade pulpar e ausência de infiltrado inflamatório no tecido conjuntivo. Somente o grupo MTA mostrou barreira de tecido duro rodeada por odontoblastos sobre os cotos pulpares. MTA e SF 15,5% são eficazes para pulpotomias de dentes decíduos. Embora o MTA seja considerado o material de primeira escolha, o SF pode ser uma alternativa adequada quando o custo do tratamento é um problema.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Óxidos/administração & dosagem , Pulpectomia/métodos , Compostos Férricos/administração & dosagem , Compostos de Cálcio/administração & dosagem , Compostos de Alumínio/administração & dosagem , Agentes de Capeamento da Polpa Dentária e Pulpectomia , Dente Decíduo/cirurgia , Dente Decíduo/patologia , Dente Decíduo/diagnóstico por imagem , Radiografia Dentária , Resultado do Tratamento , Polpa Dentária/patologia , Combinação de Medicamentos , Dente Molar/patologia , Dente Molar/diagnóstico por imagem
16.
Braz. dent. j ; 28(1): 121-128, Jan.-Feb. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-839122

RESUMO

Abstract Although endodontic treatment is widely recommended for compromised dental pulp, there is no information regarding the factors associated with failures in primary teeth. The aim of this study was to evaluate the survival and factors associated with failure of pulpectomies performed in primary teeth by dental students. The sample comprised patients treated at a University Dental Service and required endodontic treatment in primary teeth. The study investigated treatment-related variables and patient factors potentially associated with treatment failure. Pulpectomy survival was analyzed by Kaplan-Meier estimator followed by log-rank test (p<0.05). The analysis included 81 pulpectomies performed in 62 children (5.6±1.5 years). The survival reached 62.9% up to 12 months follow-up. Most failures occurred in the first 3 months (p<0.001). Teeth with carious lesions at the start of treatment presented more failures than those with restorations or history of trauma (p=0.002). The survival of endodontically treated teeth restored with composite was higher than the ones filled with GIC (p=0.006). Pulpectomy performed in two or more sessions resulted in more failures (p=0.028). Patients presenting gingivitis had more failures in the endodontic treatment (p=0.022). The failures of root canal treatment in primary teeth were more prone to occur in a short time and when the treatment was performed in teeth presenting carious lesions. The use of composite instead of GIC increased the survival of pulpectomies. Repeated sessions for endodontic treatment and lack of oral hygiene habits had a negative effect on the results.


Resumo Embora o tratamento endodôntico seja amplamente recomendado para polpa dentária comprometida, não há informações sobre os fatores associados ás falhas nos dentes decíduos. O objetivo do trabalho foi avaliar a sobrevida e os fatores associados à falha de pulpectomias realizadas em dentes decíduos por estudantes de odontologia. A amostra foi constituída por pacientes atendidos em um Serviço Odontológico Universitário e necessitaram de tratamento endodôntico em dentes decíduos. O estudo investigou variáveis relacionadas ao tratamento e fatores do paciente potencialmente associados à falha do tratamento. A sobrevivência das pulpectomias foi analisada pelas curvas de Kaplan-Meier seguido do teste de log-rank (p<0,05). A análise incluiu 81 pulpectomias realizadas em 62 crianças (5,6 ± 1,5 anos). A sobrevida atingiu 62,9% em até 12 meses de seguimento. A maioria das falhas ocorreu nos primeiros 3 meses (p<0,001). Os dentes com lesões cariosas no início do tratamento apresentaram mais falhas do que aqueles com restaurações ou história de trauma (p = 0,002). A sobrevida de dentes endodonticamente tratados restaurados com compósito foi maior do que os preenchidos com cimento de ionômero de vidro (p = 0,006). Pulpectomias realizadas em duas ou mais sessões apresentaram mais falhas (p = 0,028). Os pacientes com gengivite apresentaram mais falhas no tratamento endodôntico (p = 0,022). As falhas do tratamento do canal radicular em dentes decíduos foram mais propensas a ocorrer em um curto período de tempo e quando o tratamento foi realizado em dentes com lesões cariosas. O uso de compósito em vez de cimento de ionômero de vidro aumentou a sobrevivência pulpectomias. Sessões repetidas para o tratamento endodôntico e a falta de hábitos de higiene bucal tiveram um efeito negativo sobre os resultados.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Pulpectomia , Estudantes de Odontologia , Dente Decíduo/cirurgia , Radiografia Dentária
17.
J Immunol ; 196(10): 4164-71, 2016 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-27053763

RESUMO

Multiple sclerosis (MS) is a major neuroinflammatory demyelinating disease of the CNS. Current MS treatments, including immunomodulators and immunosuppressants, do not result in complete remission. Stem cells from human exfoliated deciduous teeth (SHEDs) are mesenchymal stem cells derived from dental pulp. Both SHED and SHED-conditioned medium (SHED-CM) exhibit immunomodulatory and regenerative activities and have the potential to treat various diseases. In this study, we investigated the efficacy of SHED-CM in treating experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. EAE mice treated with a single injection of SHED-CM exhibited significantly improved disease scores, reduced demyelination and axonal injury, and reduced inflammatory cell infiltration and proinflammatory cytokine expression in the spinal cord, which was associated with a shift in the microglia/macrophage phenotype from M1 to M2. SHED-CM also inhibited the proliferation of myelin oligodendrocyte glycoprotein-specific CD4(+) T cells, as well as their production of proinflammatory cytokines in vitro. Treatment of EAE mice with the secreted ectodomain of sialic acid-binding Ig-like lectin-9, a major component of SHED-CM, recapitulated the effects of SHED-CM treatment. Our data suggest that SHED-CM and secreted ectodomain of sialic acid-binding Ig-like lectin-9 may be novel therapeutic treatments for autoimmune diseases, such as MS.


Assuntos
Linfócitos T CD4-Positivos/fisiologia , Meios de Cultivo Condicionados/metabolismo , Encefalomielite Autoimune Experimental/imunologia , Macrófagos/imunologia , Células-Tronco Mesenquimais/fisiologia , Microglia/imunologia , Esclerose Múltipla/imunologia , Animais , Antígenos CD/metabolismo , Linfócitos T CD4-Positivos/imunologia , Células Cultivadas , Citocinas/metabolismo , Modelos Animais de Doenças , Feminino , Humanos , Ativação Linfocitária , Camundongos , Camundongos Endogâmicos C57BL , Glicoproteína Mielina-Oligodendrócito/imunologia , Fragmentos de Peptídeos/imunologia , Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico/metabolismo , Dente Decíduo/fisiologia , Dente Decíduo/cirurgia
18.
Photomed Laser Surg ; 34(4): 171-7, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26977740

RESUMO

OBJECTIVE: This study evaluated the effect of low-level laser therapy (LLLT) on postoperative pain in children undergoing primary molar extraction. MATERIALS AND METHODS: This randomized, controlled-crossover, double-blind clinical trial was conducted with 37 children requiring bilateral extraction of primary molars. In one tooth (LLLT group), a GaAlAs diode laser (wavelength, 810 nm; continuous mode, output power 0.3 W; 180 sec, 4 J/cm(2)) was applied intraorally 1 cm from the target tissue immediately following extraction. In the contralateral tooth (control group), the hand piece was applied, but without laser activation. Children and parents rated postoperative pain on the first three evenings following extraction using, respectively, the Wong-Baker FACES(®) Pain Rating Scale (PRS) and the Visual Analogue Scale (VAS). Parents also reported if their children received analgesics. Data were analyzed using χ(2) and Mann-Whitney U tests. RESULTS: Mean VAS scores were higher for the control group than for the LLLT group on the first and second evenings, and PRS scores were higher for the control group than for the laser group on the first evening, but the differences were not statistically significant (p > 0.05). More analgesics were given to children in the control group on the first evening; however, both groups received equal amounts on the next two evenings (p > 0.05). CONCLUSIONS: Within the limitations of this study, LLLT application following primary molar extraction was not found to affect postoperative pain in children.


Assuntos
Terapia com Luz de Baixa Intensidade , Dor Pós-Operatória/prevenção & controle , Extração Dentária , Dente Decíduo/cirurgia , Analgésicos/administração & dosagem , Criança , Estudos Cross-Over , Método Duplo-Cego , Feminino , Humanos , Masculino , Dor Pós-Operatória/terapia
19.
Photomed Laser Surg ; 34(3): 116-20, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26901518

RESUMO

OBJECTIVE: This study compared the shear bond strength (SBS) of conventional welding (CW) and intraoral laser welding (LW) on fixed space maintainers (SMs), and investigated the intrapulpal temperature change (ITC) during LW. BACKGROUND DATA: Lasers have been used for intraoral welding. MATERIALS AND METHODS: The SBS test used 26 molar bands divided into two groups, CW and LW. Stainless steel wires were welded to the middle of the buccal and lingual aspects of all the bands, using an Nd:YAG laser for the LW group and silver solder and flux soldering media for the CW group. The samples, fixed to acrylic resin blocks, were subjected to shear testing. In the ITC test, 25 exfoliated primary second molar teeth were used to adapt molar bands. J-type thermocouple wire was positioned in the pulp chamber. ITCs were determined during Nd:YAG laser welding of stainless steel wires to the bands. Mann-Whitney U test was used to determine differences in SBS between the groups. ITCs were analyzed by paired t test. RESULTS: The SBS between groups showed significant differences (LW: 489.47 ± 135.70; CW: 49.71 ± 17.76; p < 0.001). The mean ITC during LW was 3.64 ± 0.79 (min: 2.4; max: 5.10). None of the samples' ITCs exceeded the critical threshold value (5.5 °C). CONCLUSIONS: LW obtained a higher-strength joint than CW. ITCs during LW do not present a thermal risk to primary teeth. The intraoral use of LW for SMs in primary teeth is recommended in terms of strength and ITCs.


Assuntos
Temperatura Corporal , Colagem Dentária/métodos , Polpa Dentária/efeitos da radiação , Terapia a Laser , Aparelhos Ortodônticos , Dente Decíduo/efeitos da radiação , Dente Decíduo/cirurgia , Soldagem/métodos , Humanos , Técnicas In Vitro , Resistência ao Cisalhamento
20.
World J Surg Oncol ; 13: 277, 2015 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-26376974

RESUMO

Here, we report the complete resolution of a calcifying cystic odontogenic tumor (CCOT) in the right mandible after marsupialization in an 8-year-old girl with a mixed dentition. Clinical, radiographic, and histopathological findings showed a simple cystic variant of CCOT in the region of the deciduous second molar, with dislocation of the permanent second premolar tooth germ. Initial treatment involved marsupialization, including extraction of the involved deciduous tooth, incision of pathological tissue, and creation of a window in the extraction socket. The crown of the dislocated second premolar was exposed at the base of the cystic cavity after marsupialization. One year and nine months later, complete bone healing and spontaneous eruption of the second premolar were observed, providing evidence of the bone regeneration capacity and tooth germ eruption potential in children. No recurrence was observed after 7 years. The findings from this case suggest that marsupialization can be successfully applied for the treatment of CCOT in children with a mixed dentition.


Assuntos
Calcinose/cirurgia , Dentição Mista , Tumores Odontogênicos/cirurgia , Erupção Dentária , Dente Decíduo/cirurgia , Calcinose/patologia , Criança , Feminino , Humanos , Tumores Odontogênicos/patologia , Prognóstico , Dente Decíduo/patologia
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