Life threatening hemorrhage associated with a dentigerous cyst in a dog: Case report.

Dentigerous cysts are the most common type of odontogenic cysts and arise from an unerupted tooth. These cysts have stereotypical radiographic and clinical findings. They can be extremely invasive but rarely present as a life-threatening emergency. This case report describes the stabilization and treatment of a 6-year-old mixed breed dog with a dentigerous cyst with concurrent life-threatening hemorrhage. The dog presented with severe oral hemorrhage from the mandibular artery and required multiple blood transfusions. It was ultimately diagnosed with a dentigerous cyst. Complications from dental issues and potential life-threatening complications, such as this case, can be prevented by routine annual oral examination and full mouth dental radiographs if an unerupted tooth is suspected.

Bilateral Dentigerous Cysts of the Permanent Mandibular First Molars Treated with Marsupialization.

Bilateral dentigerous cysts (DC) associated with unerupted mandibular first molars in a non-syndromic pediatric individual are rare. Secondary infections may lead to complications, such as discomfort due to pain, disfigurement caused by enlargement of the cyst with cortical expansion of the jawbone, displacement of teeth and paraesthesia of the adjacent nerve. This case report describes the occurrence of bilateral DC in an eight-year-old patient. Marsupialization was the treatment of choice to preserve the permanent teeth and other adjacent tissues.

The earliest known reported occurrence of dentigerous cyst in a six-month-old child.

The earliest reported case of the occurrence of a dentigerous cyst is described; the cyst surrounded an unerupted permanent tooth bud in a 6-month-old infant. Most commonly these lesions present between the second and third decades of life. They rarely occur before 10 years of age and have not been documented prior to 1 year of age. In the case reported here, the treatment instituted was extraction of the adjacent deciduous tooth and enucleation of the cyst along with the permanent molar tooth bud. Clinicians should be aware of the potential for this lesion to occur across a wide range of ages and the importance of prompt diagnosis and treatment to prevent complications and reduce morbidity.

Surgical management of compound odontoma associated with unerupted tooth: a case report.

Compound odontoma has been reported to be the most common of all odontogenic neoplasms and tumor- like lesions. It is a slow-growing, asymptomatic neoplasms found incidentally during a routine radiography examination. In general, the clinical indicators of odontoma may include eruption disturbance (non-eruption of permanent teeth, retention of deciduous teeth), expansion of the cortical bone, teeth malposition and pain. In this case, the presence of odontoma prevented the physiological eruption of permanent mandible incisor. We describe the surgical procedure to remove a compound odontoma of 21 small tooth-like structures localized in the mandible of a child boy associated with an unerupted permanent mandible incisor.

Bilateral coronoid hypoplasia and complex odontoma: a rare concurrence of developmental pathology and odontogenic tumour of the mandible.

We present a rare case of concurrent bilateral coronoid hypoplasia and complex odontoma in the mandible, with replacement of missing posterior teeth in both sides of the lower jaw. A 20-year-old woman was diagnosed with bilateral occurrence of coronoid hypoplasia and unerupted complex odontoma after radiographic and histopathological examination. The patient was surgically treated with complete removal of the unerupted complex odontoma and prosthetic replacement of the missing teeth.

Decompression as a treatment of odontogenic cystic lesions in children.

PURPOSE: To evaluate the efficiency of decompression in treating odontogenic cystic lesions of the jaws in children. MATERIALS AND METHODS: All consecutive odontogenic cysts occurring in children and treated by decompression from 1994 to 2009 at 1 maxillofacial center were included in the present study. Clinical data included age, gender, jaw, histopathologic diagnosis, and decompression time. Radiologic data from panoramic radiographs before and after decompression included tooth involvement, locularity, location, involvement of adjacent vital anatomic structures, and cyst area. RESULTS: Thirty-two odontogenic cystic lesions from 26 children (14 boys [53.8%] and 12 girls [46.2%]) treated with decompression were included. The average age at the time of presentation was 11.6 ± 3.3 years (range, 7 to 18 yr). The mandible was involved in 13 cases (40.6%) and the maxilla in 19 (59.4%). All cysts were unilocular at presentation. Twenty-seven cysts (84.4%) showed tooth involvement. The diagnoses consisted of dentigerous cysts (20 [62.5%]), keratocysts (9 [28.1%]), and radicular cysts (3 [9.4%]). The mean decompression period was 7.45 ± 2.6 months (2 to 14 months). The mean standard lesion area index changed from 12.7 ± 0.9 mm(2) (3.6 to 44 mm(2)) before compression to 2.3 ± 4.3 mm(2) (0 to 22.3 mm(2)) after decompression. The mean percentage of reduction (POR) was 82 ± 16% (49 to 100%). The POR was ranked as good in 22 lesions (69%), moderate in 9 lesions (28%), and poor in 1 lesion (3%). Surgery was performed for 15 lesions (47%). CONCLUSION: Decompression results in good regeneration potential of the bone in the developing craniofacial skeleton of children. Children might benefit from a less invasive surgical protocol.

Unerupted lower third molar extractions and their risks for mandibular fracture.

As every surgical procedure extraction of third molars can result in several complications, among them the mandibular angle fracture. Predisposing factors for fracture should be analyzed during and after the surgery. This paper aims to discuss the predisposing factors to the occurrence of mandibular angle fractures during and after the procedure for third molars extraction, as well as surgical principles to avoid this complication.

Surgical-orthodontic treatment of Class III malocclusion with agenesis of lateral incisor and unerupted canine.

INTRODUCTION: Orthodontic-surgical treatment was performed in patient with skeletal Class III malocclusion due to exceeding mandibular growth. Patient also presented upper and lower dental protrusion, overjet of -3.0 mm, overbite of -1.0 mm, congenital absence of tooth #22, teeth #13 and supernumerary impaction, tooth #12 with conoid shape and partly erupted in supraversion, prolonged retention of tooth #53, tendency to vertical growth of the face and facial asymmetry. The discrepancy on the upper arch was -2.0 mm and -5.0 mm on the lower arch. METHODS: The presurgical orthodontic treatment was performed with extraction of the teeth #35 and #45. On the upper arch, teeth #53, #12 and supernumerary were extracted to accomplish the traction of the impacted canine. The spaces of the lower extractions were closed with mesialization of posterior segment. After aligning and leveling the teeth, extractions spaces closure and correct positioning of teeth on the bone bases, the correct intercuspation of the dental arch, with molars and canines in Angle's Class I, coincident midline, normal overjet and overbite and ideal torques, were evaluated through study models. The patient was submitted to orthognathic surgery and then the postsurgical orthodontic treatment was finished. RESULTS: The Class III malocclusion was treated establishing occlusal and facial normal standards.

Surgical-orthodontic treatment of Class III malocclusion with agenesis of lateral incisor and unerupted canine

INTRODUCTION: Orthodontic-surgical treatment was performed in patient with skeletal Class III malocclusion due to exceeding mandibular growth. Patient also presented upper and lower dental protrusion, overjet of -3.0 mm, overbite of -1.0 mm, congenital absence of tooth #22, teeth #13 and supernumerary impaction, tooth #12 with conoid shape and partly erupted in supraversion, prolonged retention of tooth #53, tendency to vertical growth of the face and facial asymmetry. The discrepancy on the upper arch was -2.0 mm and -5.0 mm on the lower arch. METHODS: The pre-surgical orthodontic treatment was performed with extractions of the teeth #35 and #45. On the upper arch, teeth #53, #12 and supernumerary were extracted to accomplish the traction of the impacted canine. The spaces of the lower extractions were closed with mesialization of posterior segment. After aligning and leveling the teeth, extractions spaces closure and correct positioning of teeth on the bone bases, the correct intercuspation of the dental arch, with molars and canines in Angle's Class I, coincident midline, normal overjet and overbite and ideal torques, were evaluated through study models. The patient was submitted to orthognathic surgery and then the post-surgical orthodontic treatment was finished. RESULTS: The Class III malocclusion was treated establishing occlusal and facial normal standards.

INTRODUÇÃO: o presente trabalho apresenta um tratamento ortodôntico-cirúrgico realizado em paciente portadora de má oclusão de Classe III esquelética com crescimento mandibular, protrusão dentária superior e inferior, trespasse horizontal de -3,0mm, trespasse vertical de -1,0mm, ausência congênita do dente 22, dentes 13 e supranumerários inclusos, dente 12 com forma conoide e parcialmente irrompido em supraversão, retenção prolongada do dente 53, tendência ao crescimento vertical da face e assimetria facial. A discrepância na arcada superior era de -2,0mm, e na inferior era de -5,0mm. MÉTODOS: o tratamento ortodôntico pré-cirúrgico foi realizado com extrações dos dentes 35 e 45. Na arcada superior foram extraídos os dentes 53, 12 e supranumerário, para efetuar o tracionamento do canino incluso. Os espaços das extrações inferiores foram fechados com mesialização do segmento posterior. Após o alinhamento e nivelamento dos dentes, foram avaliados por meio de modelos de estudo o fechamento dos espaços das extrações e o posicionamento correto dos dentes nas bases ósseas, a intercuspidação correta das arcadas dentárias, com molares e caninos em Classe I de Angle, linhas medianas coincidentes, trespasse horizontal e trespasse vertical normais e torques ideais. A paciente foi encaminhada para realização de cirurgia ortognática e, em seguida, o tratamento ortodôntico pós-cirúrgico foi finalizado. RESULTADOS: a má oclusão de Classe III foi corrigida, estabelecendo padrões oclusais e faciais normais.

Unerupted teeth associated with dentigerous cysts and treated with coronectomy: mini case series.

There is a resurgence of interest in coronectomy, but its appropriate application in the management of third molar teeth has yet to be defined. Dentigerous cysts associated with unerupted teeth are most commonly associated with mandibular third molars. In this case series we evaluate outcome after coronectomy of teeth with associated dentigerous cysts in cases where the inferior dental nerve was thought to be at risk, or there was an increased risk of mandibular fracture. We retrospectively studied 21 consecutive patients treated by coronectomy for dentigerous cysts at the Oral Surgery Department at Guy's Hospital. The most commonly affected teeth were mandibular third molars (20/21). One patient had permanent injury to the inferior dental nerve, but no mandibular fracture or recurrence of cyst was reported. One patient required secondary retrieval of the retained root because of eruption. Coronectomy of unerupted teeth associated with dentigerous cysts is an effective treatment when there is high risk of injury to the inferior dental nerve injury or potential for mandibular fracture. Further work with larger numbers and longer follow-up is required to discover the long-term outcome of the electively retained root.

Cone beam CT in orthodontics: the current picture.

The introduction of cone beam computed tomography (CBCT) technology to dentistry and orthodontics revolutionized the diagnosis, treatment and monitoring of orthodontic patients. This review article discusses the use of CBCT in diagnosis and treatment planning in orthodontics. The steps required to install and operate a CBCT facility within the orthodontic practice as well as the challenges are highlighted. The available guidelines in relation to the clinical applications of CBCT in orthodontics are explored.

Adenomatoid odontogenic tumor associated with unerupted first primary molar.

Adenomatoid odontogenic tumors (AOTs) are an uncommon benign odontogenic tumor. Both central and peripheral forms occur. Radiographically, the central variants are comprised of a follicular type (those associated with the crown of an embedded tooth) and an extrafollicular type (those with no embedded tooth). A review of the literature showed that only 3 cases of an association between AOT and unerupted primary teeth have been published. The purpose of this paper was to report a rare case of adenomatoid odontogenic tumor associated with an unerupted primary first molar in a 7-year-old boy.

Association between the presence of a partially erupted mandibular third molar and the existence of caries in the distal of the second molars.

The objective of this study was to verify, using periapical radiographs, whether a partially erupted mandibular third molar is a factor in the presence of dental caries on the distal surface of the adjacent second molar. Two-forty six high quality periapical radiographs were selected, each showing a partially erupted mandibular third molar. The variables analyzed were: tooth number; gender; age; radiographic presence of caries on the distal surface of the adjacent molar; Pell and Gregory classification; Winter classification; angulation and distance between the second and mandibular third molar. The examiners were previously calibrated to collect data (kappa statistics from 0.87 to 1.0). The prevalence rate of caries on the distal surface of the second molar was 13.4%. In the logistical multivariate regression analysis, the angulation (OR=8.5; IC95%: 1.7-43.8; p=0.011) and the gender (OR=3.3; IC95%: 1.4-7.7; p=0.005) remained statistically significant after an age adjustment was made. The results indicate that the presence of a partially erupted mandibular third molar with an angulation of 31 degrees or more, is a risk factor for caries on the distal surface of the mandibular second molars.

Risk factors and prevention of bad splits during sagittal split osteotomy.

PURPOSE: One of the operative complications of the sagittal split osteotomy of the mandible is a bad split, which describes an unfavorable or irregular fracture of the mandible in the course of the osteotomy. The purpose of this study is to identify previous studies which reported incidences of bad split occurrence during sagittal split osteotomy and to discuss its mechanisms and risk factors, based on a literature review, in order to minimize their occurrence. A few illustrative cases are also presented. METHODS: An electronic search was undertaken in January 2011. The titles and abstracts from these results (n = 363) were read for identifying studies which reported incidences of bad split occurrence during sagittal split osteotomy procedures. RESULTS: Twenty-one studies were identified and assessed. The incidence of bad splits from these studies varied between 0.21% and 22.72%. The buccal plate of the proximal segment and the posterior aspect of the distal segment were the most affected areas. DISCUSSION: The surgical patient should be evaluated according to age and the presence of unerupted/impacted third molars. Prevention is focused on adequate osteotomy design, eliminating sharp angle where abnormal stress occurs on bony segments, completion of adequate cuts into the retrolingular depression and through the inferior border, and careful separation of the segments. The SSO is an extremely technical and sensitive procedure, and careful attention will probably prevent most unfavorable splits. If a fracture occurs, the fractured segments should be incorporated into the fixation scheme if possible. The occurrence of bad splits cannot always be avoided. When adequately treated the chances of functional success are good.

Unerupted lower third molars and their influence on fractures of the mandibular angle and condyle.

Our aim was to assess the influence of the presence and state of impaction of mandibular third molars on the incidence of fractures of the mandibular angle and condyle. We designed a retrospective study of patients who presented for the treatment of mandibular fractures from January 2006 to April 2011. The independent variables were the presence and degree of impaction of lower third molars, and the outcome variables were the incidence of fractures of the mandibular angle and condyle. The information was acquired from hospital records and panoramic radiographs. Personal data included age, sex, mechanism of injuries, and number of fractures of the mandibular angle and condyle. We studied 110 fractures of the mandibular condyle and 80 of the angle. The incidence of fractures of the mandibular angle was higher in the group with incompletely erupted third molars (37/80, p<0.001) and that of condylar fractures was higher in the group without (67/110, p<0.001). An incompletely erupted third molar reduces the risk of condylar fractures and increases the risk of fractures of the mandibular angle.

Associação entre caninos inclusos e agenesias de incisivos laterais superiores permanentes / Association between impacted maxillary permanent canines and agenesis of permanent lateral superior incisors

Objetivo: Avaliar a prevalência de pacientes de Ortodontia com caninos superiores permanentes inclusos (CSPI), e sua localização e associação com a agenesia dos incisivos laterais superiores permanentes (ILSP). Materiais e métodos: A amostra foi constituída a partir dos prontuários de 825 pacientes, sendo o Grupo Experimental (GE) composto de 27 pacientes, 14 do sexo feminino (idades entre 10,5 anos e 15,4 anos) e 13 do sexo masculino (idades entre 11 anos e 17,6 anos), com CSPI e o Grupo Controle (GC) por 27 pacientes sem CSPI, pareados com GE de mesma idade e sexo. Analisaram-se a anamnese, o exame clínico, os modelos, as fotografias, radiografias panorâmica, periapicais e oclusais, telerradiografias cefalométrica lateral e póstero-anterior, em ambiente escurecido com negastocópio e lupa testeira (aumento 4x). Resultados: Observaram-se 27 pacientes (3,27%), totalizando 31 caninos inclusos, 51,85% ocorreram no sexo feminino e 48,15% no masculino; o Teste de Diferença de duas proporções verificou maior número de agenesias de ILSP(7) no GE do que no GC (1) (p = 0,0255) e que a ocorrência de agenesias concentrou-se nos pacientes comCSPI na região palatina (p = 0,0227). Conclusão: A prevalência de caninos superiores permanentes inclusosé de 3,27%, mais frequente por palatino e há dependência entre a prevalência aumentada de agenesia deincisivos laterais superiores permanentes e a inclusão palatina de caninos superiores.

Objective: The purpose of this study was to evaluate the prevalence of included permanent maxillary canines (IPMC) in orthodontic patients, their location and association of agenesis of the permanent upper lateral incisors (PULI). Materials and methods: A sample from the medical records of 825 patients was analyzed. The experimental group (E.G.) was composed of 27 patients with IPMC, including 14 females (aged from 10.5 to 15.4 years) and 13 males (aged from 11.0 to 17.6 years). The control group (CG) was made up of 27 patients without IPMC, paired with E.G. of the same age and sex. We analyzed clinical histories and clinical examinations, models, photographs; also panoramic, periapical, occlusal and lateral radiographs, and lateral and antero-posterior cephalometric teleradiographs were examined in a darkened room with an illuminated viewbox and headband magnifier (4X magnification). Results: There were 27 patients (3.27%) with IPMC, totaling 31 included maxillary canines, 51,85% in females and 48.15% in males. The difference in proportions test found a higher number of cases of PULI agenesis (7) in the E.G. than in the CG (1) (p = 0.0255) and that the occurrence of agenesis was concentrated in patients with palatal IPMC (p = 0.0277). Conclusions: The prevalence of included permanent maxillary canines is 3.27%, more frequent in the palatine area. There is dependence between the increased prevalence of agenesis of permanent upper lateral incisors and palatal impaction of maxillary canines.

Conservative treatment of unicystic ameloblastoma.

INTRODUCTION: Ameloblastomas are benign asymptomatic intraosseous lesions that affect the bones of the maxillomandibular complex, interfering both in function and facial esthetic appearance. A 14-year-4-month-old girl was referred by her clinician complaining her anterior teeth were crooked and inclined forward. The lower left mandibular tooth presented with increased pericoronal space compatible with dentigerous cyst. METHODS AND RESULTS: The aim of this report is to relate a case of unicystic ameloblastoma with conservative treatment and with indication for orthodontic treatment. The conservative therapy was performed and the lesion had been completely removed. The need for radiographic and clinical follow-up for up to 10 years, initially performed every 6 months during the first 2 years and afterwards annually, in addition to the risk of late recurrence were explained for patient and her guardian. CONCLUSION: The histopathologic exam of the surgical tissue provided the final diagnosis of ameloblastoma, as the lesion had not presented in its classical form and in atypical locations, as in this case involving a tooth that had not yet erupted.

Partially erupted third molars as a potential source of infection in patients receiving peripheral stem cell transplantation for malignant diseases: a retrospective study.

Forty-four patients with malignant diseases for which they received peripheral stem cell transplant therapy (PSCT) were retrospectively studied regarding local and systemic infection originating from around partially erupted third molars (PEMs). Twenty-two patients had one or more PEMs, while 22 patients had none. Data were retrieved from medical and dental records. Systemic and local signs of infection and treatment were assessed. We recorded the number of transplanted CD34(+) blood stem cells, days with white blood cell counts < 0.5 x 10(9) l(-1), days until engraftment, maximum level of C-reactive protein (CRP), days with fever, positive blood cultures, days taking antibiotics, days drinking < 0.5 l, days of total parenteral nutrition, days receiving intravenously administered analgesics, and number of admission days. No statistically significant difference was detected between patients with PEMs and those without PEMs regarding any of the studied parameters. Of patients with PEMs, 36% (8 of 22) developed local infections around PEMs during the PSCT period. The study indicates that PEMs pose no significant risk of causing systemic infection in patients receiving PSCT for malignant diseases but increase the risk of developing a local infection, justifying close supervision and early treatment in cases of local infection during PSCT treatment.

The role of periodontal ligament cells in delayed tooth eruption in patients with cleidocranial dysostosis.

OBJECTIVE: The clinical appearance of patients with cleidocranial dysplasia (CCD), which is caused by mutations in the RUNX2 gene, is characterized by anomalies of the clavicles, thorax, spine, pelvis and extremities and by disturbances of the skull and tooth development. Of orthodontic relevance are multiple supernumerary teeth associated with delayed tooth eruption. The present investigation is based on the hypothesis that an altered phenotypic expression of periodontal ligament (PDL) cells from CCD patients and a reduced ability of those cells to support the differentiation of bone-resorbing osteoclasts might contribute to delayed tooth eruption. MATERIALS AND METHODS: To test this hypothesis, PDL cells from healthy donors and from two patients with clinically and molecular biologically diagnosed CCD were characterized for the basal and induced mRNA expression of osteoblast marker genes. The physiological relevance of the findings for the differentiation of osteoclasts was examined in an osteoclast assay, as well as in a co-culture model of PDL cells and osteoclast precursors. RESULTS: Both CCD patients displayed missense mutations of the RUNX2 gene. The in vitro experiments revealed an unaltered expression of RUNX2 mRNA, however especially in CCD patient 2 there was a reduced basal expression of mRNA for the key regulatory gene for bone remodeling RANKL. Furthermore, compared to the control cells from healthy donors, these factors were less inducible by stimulation of the cultures with 1alpha,25(OH)(2)D(3). In the osteoclast assays as well as in the co-culture experiments, PDL cells from the CCD patients showed a reduced capacity to induce the differentiation of active osteoclasts. CONCLUSIONS: These data indicate that PDL cells from CCD patients express a less distinctive osteoblastic phenotype resulting in an impaired ability to support osteoclastogenesis which might, in part, account for the delayed tooth eruption that can be observed clinically.