RESUMO
OBJECTIVES: Longitudinal assessment of the role of specific proteins on radiotherapy caries (RC) onset in head and neck cancer patients(HNC) up to one-year post-IMRT using a 5000ppm fluoride paste daily. MATERIALS AND METHODS: Dental status/salivary protein data were obtained from 40 HNC patients pre-IMRT, six months (T1) and 12 months (T2) post-IMRT (ethical approval/consent). DMFT/salivary parameters were quantified, including flow rate, mucin 5B/7, Immunoglobulin A (IgA), cystatin S and α-amylase. RESULTS: 45% patients had at least one carious lesion at T2, a significant reduction in the number of remaining teeth (65% <21), salivary flow rate (< 50%) and, protein secretion (< 0.05) post-IMRT. T1 IgA concentration/secretion rate was associated with RC (p < 0.05). Finally, IgA and total protein concentration obtained at T1 could provide a predictive pattern (AUC 82.3%) for the patients more predisposed to developing RC at T2. CONCLUSIONS: This study demonstrated the significant association of RC with salivary proteins in HNC patients treated with IMRT, revealing the potential role of salivary proteins in the early diagnosis of RC. CLINICAL RELEVANCE: This research contributes to revealing salivary proteins association with RC, and its role in early diagnosis. Therefore, this could be the first step towards personalized medicine approaches to improve this group quality-of-life.
Assuntos
Cárie Dentária , Dentifrícios , Neoplasias de Cabeça e Pescoço , Radioterapia de Intensidade Modulada , Proteínas e Peptídeos Salivares , Humanos , Cárie Dentária/prevenção & controle , Cárie Dentária/etiologia , Masculino , Neoplasias de Cabeça e Pescoço/radioterapia , Feminino , Pessoa de Meia-Idade , Estudos Longitudinais , Dentifrícios/uso terapêutico , Idoso , Fluoretos/uso terapêutico , Adulto , Índice CPO , Imunoglobulina A/análise , Saliva/metabolismoRESUMO
A evolução dos tratamentos em implantodontia possibilitou uma mudança nos tratamentos reabilitadores para pacientes edêntulos, tornando possível a colocação de próteses fixas, que proporcionam maior qualidade de vida para estes pacientes. Para que estas próteses tenham bom desempenho e longevidade satisfatórios é essencial que se mantenha um padrão adequado de higienização bucal e manutenção profissional. Assim, o objetivo deste trabalho foi realizar uma revisão de literatura a respeito dos principais recursos disponíveis para higienização e manutenção das próteses totais fixas sobre implante (protocolo de Branemark), tanto nos cuidados domiciliares dos pacientes quanto no atendimento profissional do cirurgião dentista. Foi realizada uma busca eletrônica, não sistemática, nas bases de dados Lilacs, Pubmed/Medline, Scielo e ScienceDirect, cruzando-se os seguintes descritores: "Higiene Oral"; "Implantes Dentários"; "Implantação Dentária"; "Manutenção"; "Prótese Dentária Fixada por Implante" e "Prótese Dentária". Foram consultados artigos de revisão de literatura, revisão sistemática, meta-análise, estudos clínicos randomizados, além de livros pertinentes ao assunto, publicados no período de 1995 a 2022.Verificou-se na literatura disponível que os principais instrumentos indicados para uso domiciliar são escova dental, fio dental, escova interdental, irrigador oral, dentifrício e enxaguatório. No atendimento profissional em consultório odontológico deve ser dispendida atenção especial às instruções passadas ao paciente e também fazer o possível para motivar e encorajar o seu engajamento na rotina de higienização, além do acompanhamento periodontal, possíveis substituições de parafusos e instalação de placa oclusal estabilizadora, quando necessário. Manter uma higiene oral adequada é essencial para o sucesso das próteses fixas sobre implantes e o cirurgião dentista desempenha um papel crucial não apenas ao realizar o acompanhamento periódico do paciente, mas também ao sugerir os instrumentos mais apropriados, instruir sobre a higiene oral adequada e motivar o paciente a manter a saúde bucal satisfatória(AU)
The evolution of treatments in implantology has enable a change in rehabilitation treatments for edentulous patients, making it possible to place fixed prostheses that provide a better quality of life for these patients. In order to ensure good performance and satisfactory longevity, it is essential to maintain an appropriate standard of oral hygiene and professional maintenance. Thus, the objective of this work was to conduct a literature review on the main resources available for cleaning and maintenance of complete fixed prostheses on implants (Branemark protocol), both in the patients' home care and in the professional care provided by the dentist. A nonsystematic electronic search was carried out in the Lilacs, Pubmed/Medline, Scielo, and ScienceDirect databases, crossing the following descriptors: "Oral Hygiene"; "Dental Implants"; "Dental Implantation"; "Maintenance"; "Dental Prosthesis, ImplantSupported"; and "Prosthodontics". Literature review articles, systematic reviews, meta-analyses, randomized clinical studies, and relevant books on the subject published from 1995 to 2022 were consulted. The literature available indicates that the main instruments recommended for home care are toothbrush, dental floss, interdental brush, oral irrigator, toothpaste, and mouthwash. In the professional dental office, special attention should be given to the instructions given to the patient, as well as to motivate and encourage their engagement in the hygiene routine, in addition to periodontal monitoring, possible screw replacements, and installation of an occlusal splint when necessary. Maintaining adequate oral hygiene is essential for the success of fixed prostheses on implants, and the dentist plays a crucial role, not only in providing periodic patient follow-up, but also in suggesting the most appropriate instruments, instructing on adequate oral hygiene, and motivating the patient to maintain satisfactory oral health(AU)
Assuntos
Assistência Odontológica , Odontologia Preventiva , Prótese Dentária Fixada por Implante/métodos , Dentifrícios , Odontólogos , Antissépticos BucaisRESUMO
AIM: To explore the epidemiology of plaque-induced gingivitis and related factors among Chinese adolescents. MATERIALS AND METHODS: This cross-sectional survey comprised 118,601 schoolchildren in the 12-15-year age group. Data came from the National Oral Health Survey in mainland China. The field investigation was conducted according to the World Health Organization guidelines. The new 2018 case definition for plaque-induced gingivitis was used. Participants underwent clinical examinations and completed a structured questionnaire. Bleeding on probing (BOP) was performed on all teeth. Multinomial logistic regression was used to explore the factors related to the extent of gingivitis. RESULTS: Nearly half of the study population (47.3%) had plaque-induced gingivitis; 23.9% and 23.3% presented with localised and generalised gingivitis, respectively. The first molars were the most affected by BOP. Well-established factors, such as demographic characteristics, socioeconomic status, local factors and smoking habits, were significantly associated with the extent of gingivitis. Odds ratios for localised and generalised gingivitis increased with the decrease in frequency of toothbrushing with a fluoride dentifrice. CONCLUSIONS: The study population had high plaque-induced gingivitis prevalence. The extent of gingivitis appeared to have a dose-response relationship with the frequency of toothbrushing with a fluoride dentifrice.
Assuntos
Placa Dentária , Dentifrícios , Gengivite , Adolescente , Humanos , Criança , Fluoretos , Estudos Transversais , Placa Dentária/epidemiologia , Escovação Dentária , Gengivite/epidemiologia , Índice de Placa DentáriaRESUMO
Aim: To evaluate the surface roughness and color stability of bulk-fill resin composites after simulated toothbrushing with whitening dentifrices. The radioactive/relative dentin abrasion (RDA) and radioactive/relative enamel abrasion (REA) of dentifrices were also assessed. Methods: Specimens (n=10) of Tetric N Ceram Bulk Fill (TNCB), Filtek One Bulk Fill (FOB) resin composites, and Z100(Control) were prepared using a cylindrical Teflon matrix. Surface roughness (Ra, µm) was assessed by a roughness meter and the color evaluations (ΔEab , ΔE00 , WID ) were performed using a digital spectrophotometer based on the CIELAB system. Three measurements were performed per sample, before and after simulated toothbrushing with 3D Oral-B White Perfection (3DW) and Black is White (BW) dentifrices. The abrasivity (REA and RDA values) of the used dentifrices was also determined by the Hefferren abrasivity test. Results: The Ra values increased significantly in all resin composites after 3DW and BW toothbrushing. The acceptable threshold color varied among resin composites, and TNCB and Z100 presented the highest ΔEab and ΔE00 for BW dentifrice. The 3DW dentifrice was significantly more abrasive than BW dentifrice on enamel and dentin. Conclusions: simulated toothbrushing with tested whitening dentifrices increased the surface roughness at acceptable levels. The Tetric N Ceram Bulk-fill and Z100 composite showed the highest color alteration in BW. 3D White Perfection dentifrice was more abrasive on dentin and enamel than Black is White.
Assuntos
Cor , Resinas Compostas , Esmalte Dentário , Dentifrícios , Dentina , ClareadoresRESUMO
ABSTRACT Objective: To investigate the effects of two different dentifrice fluoride concentrations on the color stability of the composite. Material and Methods: Twenty-seven specimens (2×4×5 mm) each of microfilled (Gradia, GC, Japan) and nanohybrid (Grandio, VOCO, Germany) composites were prepared. The specimens were randomly divided into six groups (control, Fluoflor caries protection toothpaste with 1450ppm Fluoride (EXW, France), and Fluoflor kids toothpaste with 500ppm Fluoride (EXW, France) (n = 9). The specimens were immersed in a mixture of artificial saliva and toothpaste in a ratio of 1:3 and applied for 60 seconds every 12 hours for 42 days. The control samples were incubated in artificial saliva at 37°C. Primary and secondary color measurements were performed using color parameters (L∗a∗b) with a spectrophotoshade (MHT Optic Research AG, Niederhasli, Switzerland). Data were analyzed using a two-way analysis of variance at a significance level of 0.05. Results: According to the two-way ANOVA analysis, there was no significant difference in color change between the composites and no difference in the level of discoloration between different fluoride concentrations(p>0.05). Also, None of the dentifrices caused clinically significant color changes(∆E˂3.3). Conclusion: No clinically unacceptable color changes were observed in the microfilled and nanofilled composites with different concentrations of fluoride toothpaste.
Assuntos
Cremes Dentais/química , Cor , Resinas Compostas/química , Fluoretos/química , Técnicas In Vitro/métodos , Análise de Variância , DentifríciosRESUMO
BACKGROUND: Smokeless tobacco (SLT) use is positively associated with oral, oesophageal, and pancreatic cancers. The tobacco dentifrice is a type of SLT which is applied to the teeth and gums. It is available in different forms which include mishri, gul/gulmanjan, gudhaku, snuff, red tooth powder, and creamy snuff. This qualitative study aims to explore the opinions and beliefs associated with the harmful effects of tobacco dentifrice use. METHODOLOGY: Thirty in-depth interviews were conducted among tobacco dentifrice users visiting a dental hospital. The data were coded and analysed using thematic analysis in ATLAS.ti software 8. RESULTS: A total of 11 codes and six categories were generated which comprised of the reason for the initiation, awareness of health effects, perception of oral tobacco application, perception of quitting, the reason for continued use, and use in society. Family, peers, access to the product, curiosity were important factors to initiate the tobacco dentifrice use. Participants believed in the myth that tobacco dentifrice was beneficial for the teeth, gums, and bowel movements. The participants considered tobacco dentifrice to be less harmful than other forms of tobacco. However, some participants were aware of its adverse effects on health and have tried to quit in the past. None of the participants had taken any professional help for quitting. CONCLUSION: There were strong beliefs and myths among the participants that tobacco dentifrice was beneficial for oral and general health. There is a need to create awareness and improve the standard of the health warning of such products.
Assuntos
Dentifrícios , Tabaco sem Fumaça , Humanos , Cognição , Dentifrícios/efeitos adversos , Índia , Uso de Tabaco , Tabaco sem Fumaça/efeitos adversosRESUMO
Introdução: O efeito branqueador dos dentifrícios contendo Blue covarine é fundamentado no seu mecanismo de ação, caracterizado pela sua deposição na superfície dentária, alterando a percepção da cor. Objetivo: Revisar a literatura e buscar evidência científica sobre o efeito branqueador do Blue Covarine em tecidos mineralizados e materiais restauradores estéticos. Materiais e métodos: Para a revisão da literatura foram feitas buscas nas bases de dados PubMed, LILACS, BBO, SciELO e MEDLINE para identificar estudos clínicos e laboratoriais que avaliassem a ação branqueadora do agente óptico Blue covarine. Como estratégia de busca foram utilizados os descritores "Blue covarine", "Blue covarine e pasta de dentes", "Blue covarine and toothpaste", "Blue covarine e dentifrícios", "Blue covarine and dentifrices", "Blue covarine e dentifrícios branqueadores", "Blue covarine and whitening dentifrices", "Blue covarine e dentifrícios clareadores", "Blue covarine and bleaching dentifrices", "Blue covarine e pasta de dentes branqueadoras", "Blue covarine and whitening toothpaste", "Blue covarine e pasta de dentes clareadoras", "Blue covarine and bleaching toothpaste". Resultados: Dois pesquisadores selecionaram e analisaram criticamente 31 artigos, sendo 2 revisões da literatura, 4 estudos clínicos e 25 estudos laboratoriais. Divergências quanto ao desenho de estudo, métodos, amostra, critérios clínicos e parâmetros laboratoriais foram observados, além de conflitos de interesse. Conclusão: O Blue Covarine presente nos dentifrícios branqueadores parece ser efetivo na promoção do branqueamento dentário apenas quando associado aos agentes abrasivos presentes nas formulações, evidenciando que ensaios clínicos e laboratoriais, com metodologias semelhantes, são necessários para se obter evidência científica conclusiva sobre o efeito deste agente branqueador.(AU)
Introduction: The whitening effect of dentifrices containing Blue Covarine is based on its mechanism of action, characterized by its deposition on the tooth surface, altering the perception of color. Objective: To review the literature and seek scientific evidence on the whitening effect of Blue Covarine on mineralized tissues and aesthetic restorative materials. Materials and methods: For the literature review, searches were carried out in the PubMed, LILACS, BBO, SciELO and MEDLINE databases, in order to identify clinical and laboratory studies that evaluated the whitening action of the optical agent Blue Covarine. As a search strategy, the descriptors "Blue Covarine", "Blue Covarine and toothpaste", "Blue Covarine and dentifrices", "Blue Covarine and whitening dentifrices", "Blue Covarine and bleaching dentifrices", "Blue Covarine and whitening toothpaste", "Blue Covarine and bleaching toothpaste". Results: Two researchers selected and critically analyzed 31 articles, including 2 literature reviews, 4 clinical studies and 25 laboratory studies. Differences in study design, methods, sample, clinical criteria and laboratory parameters were observed, in addition to conflicts of interest. Conclusion: Blue Covarine present in whitening dentifrices seems to be effective in promoting dental whitening only when associated with abrasive agents present in the formulations, showing that clinical and laboratory tests, with similar methodologies, are necessary to obtain conclusive scientific evidence on the effect of this bleaching agent.(AU)
Assuntos
Humanos , Clareamento Dental/métodos , Dentifrícios/química , Isoindóis/química , Clareadores Dentários/química , Metaloporfirinas/química , Colorimetria , Esmalte Dentário/químicaRESUMO
Introduction: fluoride toothpaste is widely used by the population. Objective: dentifrices with a high concentration of sodium fluoride and the presence of tricalcium phosphate were developed, providing additional protection to patients vulnerable to the development of caries. This study aimed to evaluate the influence of different dentifrices on the surface and internal hardness and enamel wear after artificial caries, pH cycling, and toothbrushing. Material and method: enamel blocks (4x4 mm) were obtained from 20 bovine teeth. The specimens were submitted to artificial caries lesion and then to pH cycling and brushing according to the dentifrice: Colgate Total 12 and Clinpro + Tricalcium Phosphate. Result: after this period, they were submitted to analysis of superficial and internal hardness and profilometry. Scanning Electron Microscopy (SEM) was performed. The data obtained were evaluated by one-way Analysis of Variance (ANOVA) to evaluate the mineral recovery and profilometry, and two-way repeated measures ANOVA to evaluate the superficial and internal hardness. Conclusion: analyzing the surface hardness, after caries induction, there was a significant reduction in hardness that was partially recovered regardless of the dentifrice used. For internal hardness, Clinpro obtained lower values on the control side and up to 90 micrometers on the test side. As for profilometry, Colgate Total 12 showed greater wear when compared to Clinpro. It was concluded that Clinpro promoted lower internal hardness, however, Colgate Total 12 resulted in greater surface wear of tooth enamel.
Introdução: dentifrícios fluoretados são amplamente utilizados pela população. Foram desenvolvidos dentifrícios com alta concentração de fluoreto de sódio e presença de tricálcio fosfato, fornecendo proteção adicional a pacientes vulneráveis ao desenvolvimento da cárie. Objetivo: o objetivo deste estudo foi avaliar a influência de diferentes dentifrícios na dureza superficial, interna e desgaste do esmalte após cárie artificial, ciclagem de pH e escovação. Material e método: blocos de esmalte (4x4 mm) foram obtidos a partir de 20 dentes bovinos. Os espécimes foram submetidos à lesão de cárie artificial e, em seguida, à ciclagem de pH e escovação de acordo com o dentifrício: Colgate Total 12 e Clinpro + Tricálcio Fosfato. Após este período, foram submetidos à análise de dureza superficial e interna e perfilometria. Foi realizada microscopia eletrônica de varredura. Resultado: os dados obtidos foram avaliados por ANOVA um critério para avaliar a recuperação mineral e perfilometria, ANOVA dois critérios medidas repetidas para avaliar a dureza superficial e interna. Conclusão: analisando a dureza superficial, após a indução da cárie houve uma redução significativa na dureza que foi parcialmente recuperada independente do dentifrício utilizado. Para dureza interna, Clinpro obteve valores menores no lado controle e até 90 micrômetros no lado teste. Quanto à perfilometria, o Colgate Total 12 apresentou maior desgaste quando comparado ao Clinpro. Concluiu-se que Clinpro promoveu menor dureza interna, porém, o Colgate Total 12 resultou em maior desgaste superficial do esmalte dentário.
Assuntos
Animais , Bovinos , Remineralização Dentária , Cremes Dentais , Microscopia Eletrônica de Varredura , Análise de Variância , Esmalte Dentário , Flúor , Cárie Dentária , DentifríciosRESUMO
Objective: to investigate the antimicrobial effects of toothpastes containing bioactive surface pre-reacted glass particles (S-PRG) on S. mutans biofilms adherence, initial colonization and maturation. Material and Methods: a reference UA 159 and a clinical S. mutans (SM6) strain were used. Bovine enamel specimens were randomly allocated into the groups (n=5): toothpastes containing 0%; 1%; 5%; 20%; 30% S-PRG; positive control dentifrice (NaF+triclosan); and negative control (distilled water). For biofilm development, samples were placed in a 24-well plate containing artificial saliva (4h), followed by adding 1mL of artificial saliva, BHI broth and 225µL of S. mutans suspension. Treatments with toothpastes were applied previously or after 4h and 24h of biofilm formation. Samples were incubated for 48h at 37°C in 5%CO2 and biofilm was detached and seeded in Petri dishes for determining the number of viable cells. Data were analyzed by ANOVA and Tukey test (5%). Results: significantly lower microorganisms' adherence (p<0.05) was obtained for all S-PRG toothpastes, with similar results to NaF+triclosan for SM6 and 20 and 30%S-PRG groups exhibiting higher inhibition effect than the NaF+Triclosan for UA159. Antibacterial effect on the early-stage biofilm was also observed for the S-PRG groups, but was not superior to the NaF+Triclosan toothpaste. For the mature biofilm, the effective antimicrobial potential of S-PRG toothpastes was observed only for the SM6 clinical strain, but was not higher than the positive control. Conclusion: experimental S-PRG toothpastes were effective to inhibit S. mutans biofilm growth by exhibiting antimicrobial activity, being promising agents to prevent cariogenic biofilm development (AU)
Objetivo: investigar o efeito de dentifrícios contendo S-PRG sobre a colonização inicial e maturação de biofilmes de S. mutans. Material e Métodos: uma cepa de referência (UA 159) e uma cepa clínica de S. mutans (SM6) foram utilizadas. Espécimes de esmalte bovino foram alocados nos grupos (n=5): dentifrícios contendo 0%; 1%; 5%; 20% e 30%S-PRG; controle positivo (NaF+triclosan); e controle negativo (água destilada). Os espécimes foram inseridos em uma placa de 24 poços contendo saliva artificial (4h), seguido por adição de 1mL de saliva artificial, BHI, 225µL de suspensão de S. mutans e foram tratados com suspensões de dentifrícios antes ou depois de 4 e 24h da formação do biofilme. Os espécimes foram incubados por 48h e o biofilme foi removido dos espécimes e semeado em placas de Petri para contagem de UFC/mL. Os dados foram analisados por ANOVA e teste de Tukey (5%). Resultados: houve diminuição na adesão de microrganismos para os grupos tratados com S-PRG (p<0.05). Para SM6, os dentifrícios contendo S-PRG apresentaram resultados semelhantes ao NaF+triclosan e para a cepa UA159 o dentifrício com 30%S-PRG apresentou efeito superior. Efeito antimicrobiano no biofilme recém-formado (4h) foi observado para os grupos contendo S-PRG, mas não foi observado efeito superior ao NaF+Triclosan. Para o biofilme maduro, efeito antimicrobiano do S-PRG foi observado apenas para a cepa clínica, mas não superior ao efeito do NaF+Triclosan. Conclusão: dentifrícios contendo S-PRG foram eficazes na inibição do desenvolvimento de biofilmes de S. mutans, sendo promissores agentes para prevenir o desenvolvimento de biofilme cariogênico. (AU)
Assuntos
Animais , Bovinos , Streptococcus mutans , Biofilmes , Esmalte Dentário , Placa Dentária , DentifríciosRESUMO
Objective: erosive tooth wear is a multifactorial condition that results in loss of dental hard tissue, caused by a chemical and mechanical process. This paper aims to carry out a systematic review presenting the effects of different toothpaste formulations on the loss of dental enamel surface in vitro. Material and Methods: the searches were performed in the databases PubMed, Web of Science, LILACS and Scielo. Articles published from 2010 to 2020 were filtered, without language restriction. Articles that included abrasion and erosion protocols were searched, as they were more similar to clinical reality, since toothpaste is applied through tooth brushing. The searches with descriptors and free terms on the topic resulted in 992 articles, however only 12 were within the search criteria. Results: the selected studies appointed that association of conventional fluorides (NaF) with metallic fluorides can be a promising strategy for the reduction of surface loss by erosive tooth wear. Toothpastes containing sodium fluoride, as well as tin without chitosan, showed a reduction in surface loss, considered sufficient for individuals with medium exposure to acids. In children's toothpastes, the one containing sodium fluoride showed a reduction in surface loss when compared to non-fluoride dentifrices. Conclusion: different protocols may result in less or greater loss of enamel surface, and methodological differences should be considered. To clarify the effects of dentifrices on erosive tooth wear, other properties of dentifrices should be investigated. (AU)
Objetivo: o desgaste erosivo é uma condição multifatorial que resulta em perda de tecido duro dentário, causado por um processo químico e mecânico. Este trabalho tem como objetivo realizar uma revisão sistemática de literatura apresentando os efeitos de diferentes formulações de dentifrícios na perda de superfície de esmalte dentário in vitro. Material e Métodos: a busca foi realizada nas bases de dados PubMed, Web of Science, LILACS e Scielo. Foram filtrados artigos publicados no intervalo de 2010 a 2020, sem restrição de idioma. Buscou-se artigos que incluíssem protocolos de abrasão e erosão, por mais se assemelhar a realidade clínica, uma vez que o dentifrício é aplicado através da escovação dentária. A busca com descritores e termos livres sobre o tema encontrou 992 artigos, entretanto somente 12 estavam dentro dos critérios da pesquisa. Resultados: os estudos selecionados apontaram que associação dos fluoretos convencionais (NaF) com os metálicos pode ser uma estratégia promissora para a redução de perda de superfície pelo desgaste dentário erosivo. Dentifrícios contendo fluoreto de sódio, assim como estanho sem quitosana, apresentaram redução na perda de superfície, sendo considerada suficiente para indivíduos com exposição média aos ácidos. Em dentifrícios infantis, aquele que continha fluoreto de sódio apresentou uma redução de perda de superfície quando comparado com dentifrícios sem fluoreto. Conclusão:diferentes protocolos podem resultar em menor ou maior perda de superfície de esmalte e as diferenças (AU)
Assuntos
Erosão Dentária , Dentifrícios , Desgaste dos Dentes , FlúorRESUMO
Introdução: a primeira regulamentação sobre dentifrícios fluoretados do Brasil (Portaria no 22, de 20/12/1989, da ex-Secretaria Nacional de Vigilância Sanitária) estabelecia não só a concentração máxima de fluoreto total (1500 ppm F) que um dentifrício deveria conter em termos de segurança de produto de higiene, como a mínima de fluoreto quimicamente solúvel (potencialmente ativo contra cárie) para garantir o benefício anticárie da escovação dental. Objetivo: demonstrar a necessidade e urgência de revisão da vigente regulamentação brasileira sobre dentifrícios fluoretados e registrar o posicionamento da Academia Brasileira de Odontologia. Fonte de Dados: Lilacs, PubMed, SciELO e nos arquivos do laboratório de Bioquímica Oral da FOP-UNICAMP. Síntese dos Dados: desde 1994, a Portaria nº 22 sofreu contínuas modificações culminando com a resolução ANVISA RDC No 530 de 04/08/2021. As mudanças feitas não foram baseadas no conhecimento científico mundial, do qual a Odontologia brasileira é referência. Assim, desde a primeira mudança feita em 1994, não mais foi dada importância à qualidade do fluoreto de um dentifrício, priorizando apenas a quantidade máxima de fluoreto total que ele deveria conter. Dezenas de publicações científicas tem sido feitas alertando para esse erro histórico, mas até o momento se mostraram infrutíferas. Trata-se de problema de saúde pública, pois em acréscimo tem afetado a população mais vulnerável à cárie dentária. Conclusão: a necessidade e urgência da revisão da resolução ANVISA nº 530, requer ação da sociedade como um todo, razão desta revisão e posicionamento formal circunstanciado da Academia Brasileira de Odontologia (AcBO).
Introduction: the first Brazilian regulation on fluoride toothpastes (Ordinance No 22 of 12/20/1989, of the National Health Surveillance Secretariat) established not only the maximum concentration of total fluoride (1500 ppm F) that a toothpaste should contain in terms of safety oral hygiene product, but also the minimum concentration of fluoride chemically soluble fluoride (potentially active against caries) that should contain to have ensure the anticaries benefit of toothbrushing. Objective: to prove the need and urgency of reviewing the current Brazilian regulation on fluoridated toothpastes and record the statement of the Brazilian Academy of Dentistry. Sources of data: Lilacs, PubMed, and SciELO databases and in the files of the Laboratory of Oral Biochemistry from FOP-UNICAMP. Synthesis of data: since 1994, the Ordinance No. 22 underwent continuous changes, culminating in 08/04/2021 with the resolution ANVISA RDC No 530. The changes made were not based on the best scientific evidence of the subject, that has the Brazilian Dentistry as an international reference. Thus, since the first change made in 1994, less importance has been given to the quality of fluoride in a toothpaste than the maximum amount of total fluoride that it should contain. Dozens of scientific publications have been made warning of this historic mistake, but so far, they have been shown fruitless. It is a public health problem that affects mainly underprivileged populations, who are most vulnerable to dental caries. Conclusion: the need and urgency for a revision of the Brazilian regulation ANVISA RDC No 530 to ensure that the population receives fluoride toothpaste with a minimum concentration of soluble fluoride with anticaries potential is the reason of this review and the formal position of the Brazilian Academy of Dentistry (AcBO).
Assuntos
Fluoretação/legislação & jurisprudência , Dentifrícios/análise , Saúde Pública , Cárie Dentária , Academias e InstitutosRESUMO
Introdução: os dentifrícios antiplaca e anticálculo contêm, em sua composição, agentes específicos para o controle e a redução do biofilme dentário, como o citrato de zinco, o óxido de zinco e o pirofosfato tetrassódico, dentre outros. Objetivo: avaliar in vitroa ação de dentifrícios antiplaca e anticálculo na variação da massa e da rugosidade superficial do esmalte bovino submetido à escovação simulada por 6 e 12 meses.Metodologia: 40 corpos de prova (CP) foram randomizados e divididos aleatoriamente em 4 grupos (n=10): grupo controle (GC- água) e 3 grupos teste (GT1 Colgate-Total® 12 Clean Mint, GT2 Colgate-Total® 12 Anti-Tártaro, GT3 Prevent® Antiplaca). Os CP foram submetidos à escovação simulada por 6 e 12 mesese as avaliações da massa e da rugosidade foram realizadas após cada período de escovação. Resultados: a análise da variação da massa demonstrou que não houve diferença significativa entre os grupos e os tempos. A avaliação da rugosidade demonstrou que, após 12 meses de escovação, o GT1 apresentou aumento significativo da rugosidade, quando comparado aos grupos controle e testes, enquanto os grupos GT2 e GT3 apresentaram comportamento semelhante após um ano de escovação, promovendo o polimento superficial do esmalte bovino. Conclusão: a escovação com os dentifrícios antiplaca ou anticálculo não promoveu perda significativa da massa no esmalte bovino e promoveu seu polimento.
Introduction: Antiplaque and anticalculus dentifrices contain in their composition specific agents for the control and reduction of dental biofilm, such as zinc citrate, zinc oxide, tetrasodium pyrophosphate, among others. Objective: To evaluate in vitro the action of antiplaque and anticalculus dentifrices on the variation of mass and surface roughness of bovine enamel submitted to simulated brushing for 6 and 12 months. Metodology: 40 specimens (PB) were randomized and randomly divided into 4 groups (n=10): control group (GC water) and 3 test groups (GT1 Colgate-Total® 12 Clean Mint, GT2 Colgate-Total® 12 Anti-Tartar, and GT3 Prevent®Antiplaque). The PB were submitted to simulated brushing for 6 and 12 months and the mass and roughness evaluations were performed after each brushing period. Results: The analysis of mass variation showed that there was no significant difference between groups and times. The roughness evaluation showed that after 12 months of brushing, GT1 showed a significant increase in roughness when compared to the control and test groups, while the GT2 and GT3 groups showed similar behavior after one year of brushing, promoting the surface polishing of bovine enamel. Conclusion: Brushing with antiplaque or anticalculus dentifrices did not promote significant mass loss in bovine enamel and promoted its polishing.
Assuntos
Animais , Doenças Periodontais , Escovação Dentária , Produtos Biológicos , Técnicas In Vitro , Cálculos Dentários , Esmalte Dentário , DentifríciosRESUMO
La hipersensibilidad de la dentina surge ante la exposición de esta y en respuesta a estímulos de diverso tipo, fundamentalmente de origen térmico, evaporativo, táctil, osmótico o químico. Se realizó una investigación abocada a caracterizar la hipersensibilidad dental de pacientes atendidos en consulta de odontología y la respuesta a determinado dentífrico utilizado. En el análisis de estimulación dental se tomaron 308 mediciones de la sensibilidad dental para todos los participantes (n=22), con 7 factores de tiempo (T0 antes del uso del producto, T3 días, T5 días, T8 días, T22 días y T29 días después del uso del dentífrico). Se realizó la prueba paramétrica regresión lineal simple para identificar la tendencia y el ajuste de los datos, al considerar dichas variables como una serie temporal. Se utilizaron 22 tratamientos. Casi el 91,0% expreso que el dentífrico había cumplido sus expectativas, fundamentalmente por la reducción de la hipersensibilidad a corto plazo, mientras que aproximadamente 91,0% de los casos afirmó que compraría el dentífrico (20 casos, IC 95%: 72,2% y 97,5%), respectivamente(AU)
Dentin hypersensitivity arises when exposed to it and in response to various types of stimuli, mainly of thermal, tactile evaporative, osmotic or chemical origin. An investigation was carried out aimed at characterizing the dental hypersensitivity of patients seen in the dental office and the response to a certain toothpaste used. In the dental stimulation analysis, 308 measurements of tooth sensitivity were taken for all participants (n = 22), with 7 time factors (T0 before use of the product, T3 days, T5 days, T8 days, T22 days and T29 days after using the toothpaste). The simple linear regression parametric test was performed to identify the trend and the fit of the data, considering these variables as a time series. 22 treatments were used. Almost 91.0% believed that the toothpaste had met their expectations, mainly due to the reduction in hypersensitivity in the short term, while approximately 91.0% of the cases stated that they would buy the toothpaste (20 cases, 95% CI: 72 , 2% and 97.5%), respectively(AU)
Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Cremes Dentais , Dentifrícios , Sensibilidade da Dentina/diagnóstico , Periodontite Crônica/diagnóstico , Reação em Cadeia da Polimerase , Antissépticos BucaisRESUMO
Abstract The desire of individuals to have whiter teeth increases the interest in tooth whitening products. Our aim was to in vitro study the whitening effect of hydrogen peroxide, blue covarine and active charcoal containing whitening toothpastes on human teeth. A total of 40 extracted human incisor teeth were used in the study. To measure the whitening effect of toothpastes, the teeth were divided into four subgroups and placed in the phantom tooth jaw model. Then, daily brushing was done with an electric toothbrush. The colors of the teeth were measured initially using the spectrophotometer (single point and bleached shade mode) and at the end of 7th, 14th and 28th days. Whitening effectiveness of toothpastes were studied according to CIEDE2000 formula (ΔE00) and shade guide units (SGU). One- way analysis of variance (ANOVA) and Tukey test were used in the statistical analysis of the data. (p0.05). Blue covarine containing toothpaste had statistically the lowest whitening effect (p<0.05). All toothpastes showed a whitening effect on the teeth after 7 days of use. Activated charcoal containing toothpaste showed more whitening effect after 28 days of use than hydrogen peroxide, blue covarine and traditional toothpaste.
Resumen El deseo de los individuos de tener unos dientes más blancos aumenta el interés por los productos de blanqueamiento dental. Nuestro objetivo fue estudiar el efecto blanqueador de las pastas dentales blanqueadoras que contienen peróxido de hidrógeno, covarina azul y carbón activo en dientes humanos in vitro. En el estudio se utilizaron un total de 40 dientes incisivos humanos extraídos. Para medir el efecto blanqueador de los dentífricos, los dientes se dividieron en cuatro subgrupos y se colocaron en el modelo de diente fantasma en mandíbula. A continuación, se realizó un cepillado diario con un cepillo eléctrico. El color de los dientes se midió inicialmente con un espectrofotómetro (modo de punto único y tono blanqueado) y al final de los días 7, 14 y 28. Se estudió la eficacia blanqueadora de los dentífricos según la fórmula CIEDE2000 (ΔE00) y las unidades de guía de color (SGU). En el análisis estadístico de los datos se utilizó el análisis de varianza de una vía (ANOVA) y la prueba de Tukey. (p0,05). El dentífrico que contiene covarina azul tuvo estadísticamente el menor efecto blanqueador (p<0,05). Todos los dentífricos mostraron un efecto blanqueador en los dientes después de 7 días de uso. Los dentífricos con carbón activado mostraron un mayor efecto blanqueador tras 28 días de uso que el peróxido de hidrógeno, la covarina azul y el dentífrico tradicional.
Assuntos
Clareamento Dental , Dentifrícios , Peróxido de Hidrogênio/análiseRESUMO
The aim of this randomized double-blinded study was to evaluate the enamel surface roughness and color change after one month of whitening toothpaste use and the color stability obtained 1 month after its interruption. 30 volunteers were divided into 3 groups (n = 10) corresponding to the dentifrices: 1) Colgate Total 12 Clean Mint (TD) (Control), 2) Colgate Luminous White (LW) and 3) Sensodyne Whitening Extra Fresh (SB). The volunteers were impression with addition silicone to obtain an epoxy resin replica of the upper central incisor for the initial surface roughness evaluation using a profilometer and the initial color of the incisors and canines was evaluated with a spectrophotometer after one week of wash-out. After 1 month, the color of the central incisors and canines was measured again, and the volunteers were molded to obtain a second replica to the final roughness analysis. Data were submitted to ANOVA-one way (p≤0.05). The results showed that there was no statistical difference between the dentifrices for color difference and surface roughness for all the studied conditions. It was possible to conclude that the whitening dentifrices used in this study were not able to alter the initial color of the teeth and did not cause changes in the surface roughness of enamel.
Assuntos
Clareamento Dental , Cor , Esmalte Dentário , DentifríciosRESUMO
Objective: To analyze the wettability on the surface of eroded dentin in teeth submitted to abrasive wear with desensitizing dentifrices. Material and Methods: Bovine dentin specimens were polished and immersed in 10 mL of citric acid (pH=3.2) for 2 h. The eroded specimens were submitted to mechanic brushing according to the 4 dentifrices adopted: Colgate Total (control); Colgate Sensitive Pro-Relief; Sensodyne Repair & Protect; or Sensodyne Rapid Relief. Afterwards, it was conditioned in 37% aqueous phosphoric acid solution. Wettability of 80 specimens (n=10) brushed for 7 or 21 days was evaluated by measuring the contact angle between the dentin surface and a drop of the adhesive Single Bond Universal® (3M) with a goniometer. Changes in the surface morphology of 12 specimens (n = 3) brushed for 21 days were followed by confocal laser scanning microscopy (CLSM). Data were analyzed by two-way ANOVA and Tukey test (p > 0.05). Results: Groups treated with desensitizing dentifrices did not differ significantly (p ≤ 0.05). Surface treatment and abrasive wear did not interact significantly (p ≤ 0.05). Brushing along 7 days gave the smallest contact angle value (p ≥ 0.05). CLSM images showed morphological changes for all the groups. Conclusion: The desensitizing dentifrices did not interfere in eroded dentin wettability after brushing along 7 or 21 days. Brushing with any of the dentifrices along 21 days promoted open dentinal tubules.(AU)
Objetivo: Analisar a aplicação de um adesivo na superfície de dentina erodida em dentes submetidos ao desgaste abrasivo com agentes dessensibilizantes. Material e Métodos: Espécimes de dentina bovina foram polidos e imersos em 10 mL de ácido cítrico (pH=3,2) por 2 h. Os espécimes erodidos foram submetidos à escovação mecânica de acordo com os 4 dentifrícios adotados: Colgate Total (controle); Colgate Sensitive Pro-Alívio; Sensodyne Repair & Protect; ou Sensodyne Rápido Alívio. Em seguida, foram condicionados em ácido fosfórico a 37%. A molhabilidade de 80 espécimes (n=10) escovados por 7 ou 21 dias foi avaliada medindo-se o ângulo de contato entre a superfície dentinária com uma gota do adesivo Single Bond Universal® (3M) por um goniômetro. Alterações na morfologia da superfície de 12 espécimes (n = 3) escovados por 21 dias foram seguidos por Microscopia Confocal de Varredura a Laser (MCVL). Os dados foram analisados por ANOVA dois fatores e teste de Tukey (p > 0,05). Resultados: Os grupos tratados com dentifrícios dessensibilizantes não diferiram significativamente (p ≤ 0,05). O tratamento de superfície e o desgaste abrasivo não interagiram significativamente (p ≤ 0,05). A escovação ao longo de 7 dias apresentou o menor valor de ângulo de contato (p ≥ 0,05). As imagens do MCVL mostraram alterações morfológicas para todos os grupos. Conclusão: Os dentifrícios dessensibilizantes não interferiram na molhabilidade da dentina erodida após escovação ao longo de 7 ou 21 dias. A escovação com qualquer um dos dentifrícios ao longo de 21 dias promoveu a abertura dos túbulos dentinários (AU)
Assuntos
Animais , Bovinos , Escovação Dentária , Molhabilidade , Dentifrícios , Dentina , Dessensibilizantes DentináriosRESUMO
Aim: To propose a new method to determine in vitro potentially bioavailable fluoride (F) in diet and toothpaste after ingestion. Methods: Diet samples (D) were obtained from 15 portions of a meal served to children in a day care centre. To simulate the ingestion of toothpaste during brushing after meals, a specific amount of toothpaste was added to the diet samples (D + T). F was determined in D and D + T after incubation in a solution that simulated "gastric juice" (0.01 M hydrochloric acid) at 37oC for 30, 60 and 120 min. Microdiffusion facilitated by HMDS was used to determine the total F concentrations in samples D and D + T. The analyses were performed using an ion specific electrode. Results: For D samples, incubation in "gastric juice" for 30, 60 and 120 min resulted in F concentrations (µg F/mL) of 0.75 ± 0.06c, 0.77 ± 0.07c and 0.91 ± 0.09b, corresponding to 75.3, 77.3 and 90.7% of the total F (1.02 ± 0.12a), respectively (p = 0.0001; ANOVA + Tukey). For D + T samples, these values of F concentrations (µg F/mL) were 2.55 ± 0.46b, 2.83 ± 0.44ab and 3.15 ± 0.37a, corresponding to 86.9, 94.8 and 106.7% of the total F (2.99 ± 0.34a), respectively (p = 0.0023; ANOVA + Tukey). Conclusion: Then, it can be concluded that the proposed method of "gastric juice" is a promising protocol for determining potentially bioavailable fluoride in the diet and toothpaste after ingestion. However, additional studies are desirable
Assuntos
Cremes Dentais , Dentifrícios , Dieta , Fluoretos , Fluorose DentáriaRESUMO
ABSTRACT: There is insufficient information about the chairside polishing methods of polyether ether ketone material. Therefore, it is aimed in this study to investigate the effects of different polishing processes on polyether ether ketone surface roughness and hardness. A total of 66 disc-shaped specimens made of polyether ether ketone were used in this study. The specimens were polished conventionally and randomly divided into three groups (n=22). One group was designated as the control group, and no further treatment was applied. In the other two groups, the specimens' surfaces were abraded with diamond burs and polished using two different polishing kits. Their surface roughness and Vickers hardness were measured, and environmental scanning electron microscopy and atomic force microscopy examinations were performed. The data were statistically analysed using analysis of variance and Tukey's honest significant difference test (α=0.05). There were no statistically significant differences between the control and polishing kit groups in terms of either surface roughness or Vickers hardness (p>0.05). The polishing kits can be used reliably and effectively for polishing polyether ether ketone materials.
RESUMEN: No existe información suficiente sobre los métodos de pulido del material poliéter éter cetona. Por tanto, este estudio tiene como objetivo evaluar el efecto de diferentes procedimientos de pulido sobre la rugosidad y dureza de superficie de un material a base de poliéter éter acetona. Un total de 66 muestras en forma de disco fueron realizadas. Los especímenes fueron divididos en tres grupos (n=22). Un grupo fue designado como grupo de control, siendo que no se aplicó ningún tratamiento. En los otros dos grupos, las superficies de las muestras se lijaron con fresas de diamante y se pulieron con dos kits de pulido diferentes. Se investigó la rugosidad de superficie y la dureza Vickers en los diferentes grupos. También fueron evaluadas muestras representativas en microscopía electrónica de barrido y microscopía de fuerza atómica. Los datos se analizaron estadísticamente mediante el análisis de varianza (ANOVA) y el método de Tukey (α=0.05). No hubo diferencias estadísticamente significativas entre los grupos en términos de rugosidad de superficie o Dureza Vickers (p>0,05). Los kits de pulido se pueden utilizar de forma eficaz para el pulido de materiales a base de poliéter éter acetona.
Assuntos
Polietilenos , Polimento Dentário , Dentifrícios/análiseRESUMO
The objective of this study was to compare the antigingivitis and antiplaque efficacy of an oral hygiene system versus a control regimen. This was a single-center, randomized, examiner-blind, two-treatment, 12-week parallel group study in adults with evidence of gingivitis and plaque. Eligible subjects were stratified by baseline gingivitis and plaque scores, number of bleeding sites, and tobacco use and randomized to one of two treatment groups: (1) oral hygiene system (test group) involving a novel smart-connected Oral-B® iO oscillating-rotating (O-R) electric toothbrush, 0.454 percent stabilized stannous fluoride (SnF2) dentifrice, 0.07 percent cetylpyridinium chloride (CPC) rinse, and floss, or (2) control regimen involving a manual toothbrush and 0.243 percent sodium fluoride dentifrice. Gingivitis (modified gingival index, gingival bleeding index) and plaque (Rustogi modification of the navy plaque index) were assessed at Baseline, Week 1, and Week 12.
Assuntos
Placa Dentária , Dentifrícios , Gengivite , Adulto , Placa Dentária/prevenção & controle , Índice de Placa Dentária , Desenho de Equipamento , Gengivite/prevenção & controle , Humanos , Higiene Bucal , Método Simples-Cego , Escovação DentáriaRESUMO
Introdução: os dentifrícios clareadores têm sido desenvolvidos para oferecer um melhoramento estético, porém por apresentarem maior abrasividade podem desenvolver efeitos adversos na superfície de materiais restauradores, como um aumento da rugosidade superficial, comprometendo a sobrevida das restaurações. Objetivo: analisar a rugosidade e o comportamento da massa de duas resinas compostas submetidas em laboratório à escovação com água destilada (controle) e com dentifrício abrasivo (DA) Colgate Luminous White®. Metodologia: foram confeccionadas 40 amostras, 20 a partir da Resina fotopolimerizável Opallis Lab® e 20 de blocos para sistema CAD/CAM Brava Block®, divididos em quatro grupos: Opallis Lab® + água destilada, Opallis Lab® + DA, Brava Block® + água destilada, Brava Block® + DA. As amostras foram pesadas e a rugosidade aferida antes e após a escovação. Foi utilizada uma máquina de escovação em 14.690 ciclos para simulação de um ano de escovação. Os dados foram tabulados e analisados quanto à variância (ANOVA) e posteriormente realizados o teste de Tukey, comparando as médias, duas a duas. Resultados: quanto ao DA, a resina fotopolimerizável apresentou comportamento limítrofe comparado ao grupo controle, já o bloco CAD/CAM foi estatisticamente significante. Em ambos, a rugosidade reduziu no grupo controle enquanto que no grupo teste aumentou. A perda de massa apenas, foi estatisticamente significante na resina fotopolimerizável. Quando comparados os tipos de resina, não houve significância estatística quanto à rugosidade e a perda de massa. Conclusão: as resinas apresentam comportamentos semelhantes, mas os dentifrícios abrasivos não são recomendados para escovação de materiais restauradores, pois interferem negativamente na rugosidade
Introduction: whitening dentifrices have been developed to offer an aesthetic improvement, however because of their high abrasiveness, may develop adverse effects on the surface of restorative materials, may develop adverse effects on the surface of restorative materials, such as increased surface roughness, compromising the survival of restorations. Objective: analyze the roughness and mass loss of two laboratory composite resins subjected to brushing with distilled water (control) and with abrasive dentifrice (AD), Colgate Luminous White®. Methodology: were prepared 20 samples, 20 from light-curing resin Opallis Lab® and 20 from blocks for CAD/CAM system (Brava Block®), divided into four groups: Opallis Lab® + distilled water, Opallis Lab® + AD, Brava Block® + distilled water, Brava Block® + AD. The samples were weighed and the roughness measured before and after brushing. A brushing machine was used in 14,690 cycles simulating 1 year of brushing. Data were tabulated and analyzed for variance (ANOVA) and later performed the Tukey test, comparing the means, two to two. Results: as for the AD, the light-curing resin presented borderline behavior compared to the control group, when the CAD/CAM block was statistically significant. In both, the roughness decreased in the control group while in the test group it increased. The weight loss was only statistically significant in the light-cured resin. When comparing the types of resin, there wasn't statistical significance as for roughness and weight loss. Conclusion: the tested resins have similar behaviors, but abrasive dentifrices are not recommended for brushing restorative materials, because they interfere negatively in the roughness.