An investigation into the effect of surfactants on iron oxide powder suspension formulations for fingermark development.

Iron oxide powder suspension (FePS) is a fingermark development technique that can be used on adhesive and non-porous surfaces, the efficacy of which is known to be influenced by the surfactant used in the formulation. Despite previous work optimising surfactants for use in FePS, there is limited understanding of the interactions between surfactants, powders and fingermark residue which aid the successful development of fingermarks. To better understand the effect of surfactant on development quality produced by FePS, this research assessed a wide range of surfactants of different ionic natures and evaluated their ability to develop fingermarks based on the quality of ridge detail, contrast and background development produced. It was found that surfactants play a critical role in the selective deposition of powder on fingermark residue, as formulations made with only water (no surfactant) produced heavy background deposition. The efficacy of each surfactant depended on the quality parameter considered, and the addition of some surfactants hindered fingermark development. Effective surfactants such as T20, KP and TX100 prevented background development and produced well contrasted developed marks. Poor contrast was produced by LN, SP80/T80 and T80 due to indiscriminate powder deposition either across the entire sample or preventing any powder to deposit on the surface, demonstrating the role surfactants play in allowing powder deposition in this technique. The effectiveness of a surfactant in PS was not directly dependent on its ionic nature, and most surfactants were more effective when diluted from stock concentrations. This research has provided a robust base for future work improving fundamental understanding of FePS, which will greatly aid the efficacy of future optimisation efforts.

Dermatoglyphic Profiles of Competitive Athletes: CrossFit and Ultra-Marathon / Perfiles Dermatoglíficos de Deportistas Competitivos: CrossFit y Ultramaratón

SUMMARY: In the sports field, sports are usually classified according to the predominance of the energy system used during the competition; sports like Crossfit and ultra-marathon could be totally opposite due to the needs of athletes to achieve good places. Due to the above, the objective was established to compare the dermatoglyphic profiles of CrossFit and Ultra-marathon athletes according to the predisposition of the energy systems, aerobic and anaerobic, used in the competitions. Cross-sectional descriptive study, where the dermatoglyphic profile of 21 athletes of national presence (10 crossfit and 11 ultra-marathon runners) was determined, through the Computerized Dermatoglyphic System, brand Salus Dermatoglifia, according to the Cummins and Midlo protocol, which consists of taking the fingerprints of the 10 fingers of the hands. The fingerprint designs of the human being (arch, loop and whorl) and the elements contained in them (nucleus and delta) were analyzed, differences were established through the Analysis of Variance test in the SPSS V.25 statistical package. The results show significant differences between the average scores of the line count of both disciplines (108 and 165), being higher in ultra-marathon runners, associated with greater aerobic resistance. Another significant and relevant finding was the presence of arch-type fingerprints only in CrossFit athletes associated, along with low line count, with strength and power. It is concluded that Crossfit and Ultra-marathon athletes have dissimilar natural physical characteristics, which is why they participate and excel in different sports where they have enhanced their natural physical abilities through training.

En el ámbito deportivo, los deportes suelen clasificarse según el predominio del sistema energético utilizado durante la competición; Deportes como el Crossfit y la ultramaratón podrían ser totalmente opuestos debido a las necesidades de los deportistas de conseguir buenos lugares. Debido a lo anterior, se estableció como objetivo comparar los perfiles dermatoglíficos de atletas de CrossFit y Ultramaratón según la predisposición de los sistemas energéticos, aeróbico y anaeróbico, utilizados en las competencias. Estudio descriptivo transversal, donde se determinó el perfil dermatoglífico de 21 deportistas de presencia nacional (10 crossfit y 11 ultramaratonistas), a través del Sistema Dermatoglífico Computarizado, marca Salus Dermatoglifia, según el protocolo Cummins y Midlo, el cual consta de tomando las huellas dactilares de los 10 dedos de las manos. Se analizaron los diseños dactilares del ser humano (arco, asa y verticilo) y los elementos contenidos en ellos (núcleo y delta), se establecieron diferencias mediante la prueba de Análisis de Varianza en el paquete estadístico SPSS V.25. Los resultados muestran diferencias significativas entre las puntuaciones medias del recuento de líneas de ambas disciplinas (108 y 165), siendo superiores en los corredores de ultramaratón, asociado a una mayor resistencia aeróbica. Otro hallazgo significativo y relevante fue la presencia de huellas dactilares tipo arco sólo en atletas de CrossFit asociadas, junto con un bajo número de líneas, con fuerza y potencia. Se concluye que los atletas de Crossfit y Ultramaratón tienen características físicas naturales disímiles, por lo que participan y destacan en diferentes deportes donde han potenciado sus capacidades físicas naturales a través del entrenamiento.

Multifunctional Eu(III)-modified HOFs: roxarsone and aristolochic acid carcinogen monitoring and latent fingerprint identification based on artificial intelligence.

The exploration of multifunctional materials and intelligent technologies used for fluorescence sensing and latent fingerprint (LFP) identification is a research hotspot of material science. In this study, an emerging crystalline luminescent material, Eu3+-functionalized hydrogen-bonded organic framework (Eu@HOF-BTB, Eu@1), is fabricated successfully. Eu@1 can emit purple red fluorescence with a high photoluminescence quantum yield of 36.82%. Combined with artificial intelligence (AI) algorithms including support vector machine, principal component analysis, and hierarchical clustering analysis, Eu@1 as a sensor can concurrently distinguish two carcinogens, roxarsone and aristolochic acid, based on different mechanisms. The sensing process exhibits high selectivity, high efficiency, and excellent anti-interference. Meanwhile, Eu@1 is also an excellent eikonogen for LFP identification with high-resolution and high-contrast. Based on an automatic fingerprint identification system, the simultaneous differentiation of two fingerprint images is achieved. Moreover, a simulation experiment of criminal arrest is conducted. By virtue of the Alexnet-based fingerprint analysis platform of AI, unknown LFPs can be compared with a database to identify the criminal within one second with over 90% recognition accuracy. With AI technology, HOFs are applied for the first time in the LFP identification field, which provides a new material and solution for investigators to track criminal clues and handle cases efficiently.

Estudio Piloto Comparativo entre la Identificación Dactiloscópica y Poroscópica con Fines de Identificación Humana en el Perú / Comparative Pilot Study Between Dactyloscopy Identification and Poroscopy for Human Identification Purposes in Peru

La dactiloscopía o papiloscopía corresponde al estudio científico de las impresiones digitales, palmares y plantares, que tiene por finalidad la identificación infalible o indubitada del individuo. Existen tres niveles para identificar con mayor certeza nivel 1 (tipo o patrón dactilar), el nivel 2 (minucias o puntos característicos) y el nivel 3 (poroscopia y crestoscopia). Por ello, es necesario analizar las características de las impresiones dactilares directas y las huellas dactilares directas con la finalidad de verificar la presencia de puntos y poros característicos para mejorar el proceso de identificación humana. Se analizaron 80 muestras (54 mujeres y 26 hom- bres). A partir de ellos, se capturaron 800 impresiones y 800 huellas dactilares directas con tampón dactilar y polvo black. En huellas con tampón se identificaron 71.25 % y 1.25 % con 14 y 6 Puntos Característicos respectivamente y en grupos de poros el 84 % y 35 % para un grupo de 1 y grupos de 7 y 8 poros respectivamente. Con polvo black solo se identificaron Puntos Característico y no Poros. La cantidad de poros en hombres fue mayor igual a 10 (LR= 2.08) y en mujeres menor igual a 6 (LR= 1.93). Los grupos de poros fueron para hombres menores o iguales a 12 poros (LR= 1.04) y mayores o iguales a grupos de 13 poros (LR=1.28) para mujeres. Se consiguieron identificar grupos de poros con tampón dactilar pero no con polvos químicos lo que podría emplearse para implementar un protocolo para el uso del nivel 3 de identificación.

SUMMARY: Dactyloscopy or papiloscopy corresponds to the scientific study of digital, palmar and plantar impressions, whose purpose is the infallible or indubitable identification of a subject. There are three levels to identify with greater certainty level 1 (type or fingerprint pattern), level 2 (minutiae or characteristic points) and level 3 (poroscopy and crestoscopy). Therefore, it is necessary to analyze the characteristics of direct fingerprints and direct fingerprints in order to verify the presence of characteristic points and pores to improve the human identification process. 80 samples (54 women and 26 men) were analyzed. Of these, 800 impressions and 800 direct fingerprints with fingerprint buffer and black powder were captured. In footprints with buffer, 71.25 % and 1.25 % were identified with 14 and 6 Characteristic Points respectively and in groups of pores 84 % and 35 % for a group of 1 and groups of 7 and 8 pores respectively. With black powder, only Characteristic Points and no Pores were identified. The number of pores in men was greater than 10 (LR= 2.08) and in women less than 6 (LR= 1.93). The groups of pores were less than or equal to 12 pores (LR= 1.04) for men and greater than or equal to groups of 13 pores (LR=1.28) for women. It was possible to identify groups of pores with a fingerprint buffer but not with chemical powders, which could be used to implement a protocol for the use of level 3 identification.

Assessment of the Relation Between Craniofacial Tissue Profile-Morphology and Dermatoglyphics.

This study aims to evaluate the relationship between the convexity angle of facial tissue and fingerprint types by analyzing the connection between dermatoglyphic prints and facial structure. A total of 65 adults (24 females, 41 males) participated in the study. Each participant's fingerprint was analyzed using conventional methods of observation upon the index finger of the dominant hand. Fingerprints were classified into 3 fundamental types: arch, whorl, or loop. Craniofacial profiling was performed with measurements of hard tissue (Gl'-A-Pg') and soft tissue facial convexity (Gl-Sn-Pg) and total facial convexity (Gl-Prn-Pg) angles between 3 anthropological points determined on the lateral direct radiographs of the participants. Soft tissue convexity facial angle (Gl-Sn-Pg) values were found to be an average of 166.83° in females and an average of 162.05° in males. (Gl-Prn-Pg) values were found to be an average of 138.54° in females and 135.27° in males. The soft tissue profile of males showed a significantly convex structure compared with females. Also, the "whorl" type of fingerprint was found to be dominant in both sexes. There is no statistically significant difference in terms of soft tissue profile convexity in individuals belonging to the 3 different fingerprint groups. No statistically significant difference in soft tissue profile angular values between right-hand thumb and index fingerprint type groups were found among and between sexes. However, a comprehensive analysis of the relationships between the nose, lips, mouth, ear, and eyes and fingerprints of the same person may prove to be beneficial.

Dermatoglifia Aplicada à Fonoaudiologia: possibilidade de interpretação / Dermatoglyphics applied to Speech Therapy: possibility of interpretation / Dermatoglifia aplicada a la Fonoaudiología: posibilidad de interpretación

Introdução: os avanços metodológicos e tecnológicos têm se apresentado em todas as áreas da Fonoaudiologia e não seria diferente nas Ciências da Fala, especificamente na Fonética Acústica. Dermatoglifia é o estudo científico das cristas dermopapilares, encontradas na impressão digital, considerada um marcador genético e identifica habilidades físicas básicas, como força, velocidade, resistência e coordenação motora. O método dermatoglífico vem sendo utilizado no diagnóstico diferencial de algumas síndromes, assim como parte integrante de processo de avaliação da qualidade vocal de profissionais da voz falada e cantada. Objetivo: descrever uma proposta de roteiro de análise dermatoglífica (DAF), que integre a avaliação da qualidade vocal, tanto de profissionais da voz falada e cantada, quanto daqueles falantes que não usam a voz profissionalmente. Descrição: o roteiro do método dermatoglífico como possibilidade de uso para Fonoaudiologia propõe a coleta das impressões digitais, a identificação dos desenhos digitais e seu predomínio, a detecção do perfil dermatoglífico, de fórmula digital, a soma da quantidade de linhas e de deltas dos dedos das mãos e a constatação das habilidades físicas potencializadas e não-potencializadas. Considerações finais: esta comunicação aponta para a integração do método dermatoglífico ao processo avaliativo da qualidade vocal de profissionais da voz falada e cantada. Representa também uma linha de investigação acerca do enfoque das habilidades musculares de indivíduos, não apenas na área de voz, mas nas demais áreas de atuação da Fonoaudiologia, por meio do Roteiro DAF ­ Dermatoglifia Aplicada à Fonoaudiologia.

Introduction: methodological and technological advances have figured in all areas of Speech Therapy and it would not be different in speech sciences, specifically in acoustic phonetics. Dermatoglyphics is the scientific study of dermatopapillary ridges, found in fingerprints, considered a genetic marker and identifying basic physical abilities, such as strength, speed, endurance and motor coordination. The dermatoglyphic method has been used in the differential diagnosis of some syndromes, and is also an integral part of the vocal quality assessment process and spoken and singing voice professionals. Objective: to describe a proposal for a dermatoglyphic analysis script (DAF), which integrates the assessment of vocal quality, both for speaking and singing voice professionals, as well as for speakers who do not use their voice professionally. Description: the script of the dermatoglyphic method as a possible tool in Speech Therapy proposes the collection of fingerprints, the identification of the digital patterns and their predominance, the detection of the dermatoglyphic profile, of the digital formula, the sum of the number of lines and deltas of the fingers of the hands and the verification of the potentiated and non-potentiated physical abilities. Final considerations: this communication points to the integration of the dermatoglyphic method into the vocal quality assessment process of vocal and singing voice professionals. It also represents a line of inquiry about the focus on the muscular abilities of individuals, not only in the area of voice, but in other areas of activity in Speech Therapy, through the DAF Script ­ Dermatoglyphics Applied to Speech Therapy.

Introducción: Los avances metodológicos y tecnológicos se han presentado en todas las áreas de la Fonoaudiología y no sería diferente en las Ciencias del Habla, específicamente en la Fonética Acústica. La dermatoglifia es el estudio científico de las crestas dermopapilares, que se encuentran en la huella dactilar, se considera un marcador genético e identifica capacidades físicas básicas como la fuerza, la velocidad, la resistencia y la coordinación motora. El método dermatoglífico ha sido utilizado en el diagnóstico diferencial de algunos síndromes, así como parte integral del proceso de evaluación de la calidad vocal de los profesionales de la voz hablada y cantada. Objetivo: describir una propuesta de roteiro de análisis dermatoglífica (DAF), que integra la evaluación de la calidad vocal, tanto para profesionales con la voz hablada y cantada, como para aquellos locutores que no utilizan su voz profesionalmente. Descripción: el roteiro del método dermatoglífico como posibilidad de uso para la Fonoaudiología propone la toma de huellas dactilares, la identificación de dibujos digitales y su predominio, la detección del perfil dermatoglífico, de la fórmula digital, la suma del número de líneas y deltas de los dedos de las manos y la verificación de capacidades físicas potenciadas y no potenciadas. Consideraciones finales: esta comunicación apunta a la integración del método dermatoglífico al proceso de evaluación de la calidad vocal de los profesionales de la voz hablada y cantada. También representa una línea de investigación sobre el enfoque de las capacidades musculares de los individuos, no sólo en el área de la voz, sino en otras áreas de actuación de la Fonoaudiología, a través del roteiro DAF ­ Dermatoglífia aplicada a la Fonoaudiología.

Greasy fingermark detection on porous surfaces using Oil red O in a gas phase: Comparison with Oil red O in solution.

Oil Red O is a fingermark reagent that is useful for developing greasy fingermarks. Classic Oil Red O formulation is based on methanol-water solution. The use of solvent can be harmful to the forensic practitioner and the environment. Moreover, solvent can destroy hand writing and biological traces. In this paper a new solvent-free Oil red O deposition method have been proposed. Experimental method is based on Oil Red O deposition from a gas phase in reduced pressure conditions. 1728 split, greasy fingermarks deposited on paper have been developed with the new method and a benchmark one. The development results have been compared. The general performance of the new method has been found inferior to the solvent based formulation. However, in most cases both methods were comparable. This shows that the experimental method could be a possible alternative to the classic one in the cases where drawbacks connected to the solvent use are unacceptable. Even though, presented results are promising, more research and optimization is necessary, before the new method can be included into the forensic expert toolbox.

Composición corporal, dermatoglifia y resistencia aeróbica en futbolistas bogotanos categoría sub 20 / Body Composition, Dermatoglyphics and Aerobic Resistance in Sub-20 Category Footballers from Bogota, Colombia

Resumen El fútbol como disciplina ha sido objeto de numerosas investigaciones que han permitido la potenciación de las cualidades de las personas deportistas para alcanzar el máximo rendimiento deportivo. El uso de nuevas herramientas ha permitido mejorar los procesos de selección de talentos y el desarrollo de las capacidades físicas, como es el caso de la dermatoglifia, que brinda información del genotipo de un individuo. El presente estudio pretende relacionar la composición corporal, la dermatoglifia y el consumo máximo de oxígeno en jugadores de fútbol categoría sub 20. La investigación fue cuantitativa, diseño no experimental, de tipo transversal. La muestra estuvo conformada por 22 futbolistas (edad 18 ± 1.1) de un club deportivo de Bogotá, a ellos se les realizó una valoración de composición corporal, se les calculó el somatotipo, se analizaron las huellas de las manos y se midió el consumo máximo de oxígeno con el Test Course Navette. Los resultados muestran predominio del somatotipo mesomorfo balanceado (53%), alta presencia de presillas "L" (66.36%), baja presencia de arcos "A" (1.82%) y un consumo máximo de oxígeno de 53.76 ± 3.73 ml/kg/min. Además, se encontraron relaciones significativas entre componentes dermatoglíficos D10-SCTL y el somatotipo endomorfo (p < 0.05), y entre el VO₂ máximo con somatotipo endomorfo y ectomorfo (p < 0.05). Se concluye que los futbolistas se caracterizan por tener una predisposición hacia la coordinación, la resistencia y la agilidad.

Abstract Soccer has generated endless research that has enhanced athlete's qualities to achieve maximum sports performance. According to the above, the use of new tools has been implemented to improve talent selection processes and develop physical abilities, as is the case with dermatoglyphics that provides information on an individual's genotype. The present study aims to relate body composition, dermatoglyphics, and maximum oxygen consumption in soccer players' category sub-20. The research had a quantitative, non-experimental, cross-sectional design. The sample comprised 22 players (age 18±1.1) from Bogota Sports Club, Colombia. They were assessed for body composition, the somatotype was calculated, handprints were analyzed, and the maximum oxygen consumption was measured with the Test Course Navette. The results show a predominance of balanced mesomorph somatotype (53%), high presence of "L" ridges (66.36 %), low presence of "A" arches (1.82%), and maximum oxygen consumption of 53.76±3.73 ml/kg/min. Furthermore, significant relationships were found between D10-SCTL dermatoglyphic components and the endomorph somatotype (p <0.05), and between the maximum VO₂ with endomorph and ectomorph somatotype (p <0.05). It is concluded that soccer players are characterized by having a predisposition towards coordination, resistance, and agility.

Resumo O futebol como disciplina tem sido objeto de inúmeras investigações que permitiram melhorar as qualidades dos desportistas para alcançar o máximo desempenho desportivo. A utilização de novas ferramentas tornou possível melhorar os processos de seleção de talentos e o desenvolvimento de capacidades físicas, como a dermatoglifia, que fornece informações sobre o genótipo de um indivíduo. O presente estudo visa relacionar a composição corporal, dermatoglifos e o consumo máximo de oxigênio nos jogadores de futebol sub-20. A pesquisa foi quantitativa, não-experimental e transversal. A amostra consistiu em 22 jogadores de futebol (18 ± 1,1 anos) de um clube desportivo de Bogotá, que foram submetidos a uma avaliação da composição corporal, foi calculado o somatotipo, foram analisadas as impressões digitais das mãos e foi medido o consumo máximo de oxigénio através do teste Course Navette. Os resultados mostram uma predominância do somatotipo mesomorfo balanceado (53%), presença elevada de presilha em "L" (66,36%), baixa presença de arcos em "A" (1,82%) e um consumo máximo de oxigênio de 53,76 ± 3,73 ml/kg/min. Além disso, foram encontradas relações significativas entre os componentes dermatoglíficos D10-SCTL e o somatotipo endomorfo (p < 0,05), e entre VO₂ máximo com somatotipo endomorfo e ectomorfo (p < 0,05). Conclui-se que os jogadores de futebol são caracterizados por uma predisposição para a coordenação, resistência e agilidade.

Latent fingermark detection using functionalised silicon oxide nanoparticles: Investigation into novel application procedures.

Investigations into the application of carboxyl-functionalised silicon oxide nanoparticles doped with a ruthenium complex (RuBpy-doped CES-SiO2 NPs) for latent fingermark development on non-porous surfaces were reported in previous studies. These studies suggested that an optimised NP-based method demonstrated advantages in fingermark selectivity and sensitivity. To continue the series of research into using RuBpy-doped CES-SiO2 NPs for fingermark detection, the versatility and overall practicality of the optimised SiO2 NP-based reagent for latent fingermark detection and enhancement was evaluated. When the optimised NP-based method was used in a repeated fashion (application of multiple NP treatment cycles), it was found that the overall fingermark detection quality increased across the evaluated fingermarks without a high risk of overdevelopment. The possibility of incorporating the optimised NP-based reagent for potential operational use (e.g., at crime scenes) was successfully demonstrated via spray application on three test surfaces (aluminium foil, transparent polypropylene film and green polyethylene film). It was also shown that further enhancement of "spray-detected" fingermarks was achievable via subsequent treatment using the NP-based reagent in a colloidal dispersion bath. Additionally, the compatibility of the optimised NP-based method with two-step cyanoacrylate fuming for latent fingermark detection was evaluated. It was concluded that the two techniques are not compatible for application in a fingermark detection sequence. While encouraging results were demonstrated in this study, further optimisation and comparison will be required before the multiple-treatment and spray-treatment approaches can be considered for operational implementation.

Exploring the problem of determining human age from fingermarks using MALDI MS-machine learning combined approaches.

For over a century fingerprints have been predominantly used as a means of biometric identification. Notwithstanding, the unique pattern of lines that can contribute to identifying a suspect is made up of molecules originating from touch chemistry (contaminants) as well as from within the body. It is the latter class of molecules that could provide additional information about a suspect, such as lifestyle, as well as physiological, pharmacological and pathological states. An example of the physiological state (and semi-biometric information) is the sex of an individual; recent investigations have demonstrated the opportunity to determine the sex of an individual with an 86% accuracy of prediction based on the peptidic/protein profile of their fingerprints. In the study presented here, the first of its kind, a range of supervised learning predictive methods have been evaluated to explore the depth of the issue connected to human age determination from fingermarks exploiting again the differential presence of peptides and small proteins. A number of observations could be made providing (i) an understanding of the more appropriate study design for this kind of investigation, (ii) the most promising prediction model to test within future work and (iii) the deeper issues relating to this type of determination and concerning a mismatch between chronological and biological ages. Particularly resolving point (iii) is crucial to the success in determining the age of an individual from the molecular composition of their fingermark.

Limb development genes underlie variation in human fingerprint patterns.

Fingerprints are of long-standing practical and cultural interest, but little is known about the mechanisms that underlie their variation. Using genome-wide scans in Han Chinese cohorts, we identified 18 loci associated with fingerprint type across the digits, including a genetic basis for the long-recognized "pattern-block" correlations among the middle three digits. In particular, we identified a variant near EVI1 that alters regulatory activity and established a role for EVI1 in dermatoglyph patterning in mice. Dynamic EVI1 expression during human development supports its role in shaping the limbs and digits, rather than influencing skin patterning directly. Trans-ethnic meta-analysis identified 43 fingerprint-associated loci, with nearby genes being strongly enriched for general limb development pathways. We also found that fingerprint patterns were genetically correlated with hand proportions. Taken together, these findings support the key role of limb development genes in influencing the outcome of fingerprint patterning.

BRCA1 gene polymorphism and finger dermatoglyphic patterns in Ghanaian breast cancer patients: a quantitative cross-sectional approach.

Introduction: breast cancer development is linked to mutant single nucleotide polymorphism of breast cancer type 1 (BRCA1) gene usually harboured within exon 11. It has also been linked to finger dermatoglyphics where certain patterns have been associated with breast cancer. This study suggests a possible relationship between finger dermatoglyphic patterns and single nucleotide polymorphism of BRCA1 gene. Methods: in a quantitative cross-sectional approach, finger dermatoglyphic patterns were obtained using the ink method from 70 female breast cancer patients and 70 age-matched apparently healthy females. Approximately 5 ml of venous blood was obtained from each participant from which DNA was extracted from the white blood cells collected after centrifugation. DNA was amplified and sequenced and the data aligned with the wildtype template of BRCA1 gene. Fingerprint patterns were analyzed with Chi-square. Mean frequency of fingerprint patterns was analyzed with independent student's t-test. Differences in data set with p<0.05 were statistically significant. Results: luminal B was the predominant breast cancer molecular subtype among the patients. The predominant fingerprint pattern among breast cancer participants was the loop. Six or more loops had higher frequency among breast cancer females. The predominant BRCA1 gene variant locations were c.34311, c.34320, and c.34321 with c.34311A>C being the predominant variant. Higher percentage frequency of six or more loops in relation to c.34311A>C was observed in apparently healthy females compared to breast cancer females. Conclusion: the study reports for the very first time in Ghana, BRCA1 gene variants and finger dermatoglyphics among breast cancer patients. Although the results are preliminary and inconclusive it creates an avenue for extended studies.

"Technical Note:" Optimisation of Diamond™ Nucleic Acid Dye preparation, application, and visualisation, for latent DNA detection.

A targeted sampling approach of latent DNA, deposited when a person makes contact with a surface, can prove challenging during crime scene or evidence processing, with the sampling of latent DNA often relying on the expert judgement from crime scene officers and forensic examiners. As such, the ability to use the quick and robust screening tool Diamond™ Nucleic Acid Dye (DD) was explored, with a focus on the visualisation of latent DNA on non-porous substrates, namely polypropylene, acrylic, aluminium, PVC composite material, glass, and crystalline silicon. The application of DD was performed according to methods reported in literature, where 10 µL of the dye solution (20-fold dilution of DD in 75% EtOH) was applied onto a variety of non-porous substrates via a micropipette and then subsequently visualised using a portable fluorescence microscope. It was discovered that there was scope for improvement in the reported methods due to the observation of crystal formations on all test substrates upon drying of the DD, resulting in the impaired visualisation of latent DNA and fingerprint detail. Thus, changes to the EtOH water ratio of the dye solution, and changes to the mode of dye application from a micropipette to a spray application, were explored to improve the drying time of the dye and mitigate the formation of crystals. While changes to the EtOH water ratio did not improve the overall drying time, the mode of dye application enhanced visualisation, with a spray application eliminating the formation of crystals no matter the EtOH water ratio. Visualisation with a portable Dino-Lite and Zeiss Widefield fluorescence microscope were also explored, with the Zeiss Widefield fluorescence microscope proving to be useful in whole print imaging and a more efficient imaging tool in a laboratory setting.

Fingerprint loss during combination therapy using osimertinib and anlotinib: A case report.

WHAT IS KNOWN AND OBJECTIVE: Recent studies prove that epidermal growth factor receptor (EGFR) inhibitors combined with vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) are more effective than EGFR TKI monotherapy for treatment of EGFR-mutated advanced non-small-cell lung cancer (NSCLC); however, the adverse effects associated with this treatment require further investigation. We report a case of fingerprint loss secondary to combination therapy using osimertinib (an EGFR TKI that targets mutated EGFR kinases) and anlotinib (a TKI that acts on multiple targets including mutated VEGFR kinases). CASE SUMMARY: A 55-year-old man with stage IV lung adenocarcinoma and an EGFR L858R mutation received a 5-month course of platinum-based chemotherapy and icotinib. This regimen was subsequently switched to osimertinib plus anlotinib to achieve a better tumour response. This therapy led to fingerprint loss, which recovered following discontinuation of anlotinib treatment but subsequently recurred. WHAT IS NEW AND CONCLUSION: To our knowledge, this is the first report that describes fingerprint loss during combination therapy using osimertinib and anlotinib.

Dermatoglifia como medio de hallazgo de diabetes mellitus: revisión sistemática / Dermatoglyphics as a means of finding diabetes mellitus: a systematic review

Introducción. La diabetes mellitus (DM) es una de las enfermedades crónicas más comunes, siendo una de las causas principales de mortalidad de la población mun-dial. La dermatoglifia es empleada como instrumento para el hallazgo de ciertos aspectos biológicos en diferentes poblaciones. Objetivo. Reconocer, a partir de una revisión sistemática, la relevancia que tiene la dermatoglifia como medio de hallazgo de diabetes mellitus. Metodología. Revisión de literatura científica en bases de datos como Sciencedi-rect, PubMed, Scopus y BVS, en las cuales se extrajo información después de co-rrer la ecuación de búsqueda con términos MESH. Posteriormente, fueron revisados para incluir aquellos artículos relacionados con DM y dermatoglifia. Para todo el proceso se siguió la metodología PRISMA, evaluando los artículos con la escala de sesgo de Cochrane y el nivel de evidencia y recomendación con escala SIGN. Resultados. Después de una revisión de 475 artículos, se incluyeron ocho artículos, y al ser evaluados fueron clasificados cinco artículos 2+ y tres 2-, con nivel de reco-mendación D. Conclusión. La dermatoglifía es una herramienta útil como medio de detección de la DM. Sin embargo, es necesario realizar estudios de cohortes para demostrarlo en di-ferentes poblaciones, como la colombiana. En ese sentido, se encuentra que el 70% de los artículos revisados demuestran que la predicción de hallazgo de DM es efectiva. Sin embargo, el 30% de las investigaciones dentro de esta revisión no consideran que sea una herramienta lo suficientemente óptima para descubrir la patología en la población.

Introduction. Diabetes mellitus (DM) is one of the most common chronic diseases, be-ing one of the main causes of mortality in the world population. Dermatoglyphics is used as an instrument for the discovery of certain biological aspects in different populations.Objective. To recognize, by doing a systematic review, the relevance of dermato-glyphics as a means of finding diabetes mellitus. Methodology. Review of scientific literature in databases such as Sciencedirect, PubMed, Scopus, and VHL, in which information was extracted after running the search equation with MESH terms. After that, they were revised to include those articles related to DM and dermatoglyphics. For the entire process, the PRISMA methodology was followed, evaluating the articles with the Cochrane bias scale and the level of evidence and recommendation with the SIGN scale. Results. After a review of 475 articles, eight articles were included, and when evalu-ated, five articles were classified as 2+ and three as 2-, with a level D recommendation. Conclusion. Dermatoglyphics is a useful tool as a means of detecting DM. However, it is necessary to carry out cohort studies to demonstrate this in different populations, such as the Colombian population. 70% of the reviewed articles show that the prediction of DM finding is effective. Nevertheless, 30% of the investigations within this review do not consider it to be a sufficiently optimal tool to discover the pathology in the population

Dermatoglifia e condição vocal de professores universitários / Dermatoglyphy and vocal condition of professors

RESUMO Objetivo Investigar a associação entre o perfil dermatoglífico e a condição vocal dos professores de uma instituição pública de ensino superior. Métodos Participaram do estudo 49 docentes. Foram utilizados os seguintes instrumentos de coleta: questionário sociodemográfico e Índice de Triagem para Distúrbios da Voz (ITDV). As impressões digitais foram coletadas por meio do scanner Watson Mini da Integrated Biometric e a análise realizada por meio do protocolo de Cummins e Midlo. Os resultados foram expostos em frequência absoluta. Foi realizado o teste Qui-Quadrado, com nível de significância de 5%, para verificação da associação dos sintomas vocais do ITDV com o perfil dermatoglífico. Resultados houve prevalência do gênero feminino entre os docentes universitários estudados. Quanto à classificação do perfil dermatoglífico, a maioria apresentou perfil anaeróbico. Observou-se associação estatisticamente significativa apenas entre perfil dermatoglífico e carga horária semanal. Conclusão a maioria dos sujeitos de perfil anaeróbico teve maior frequência de sintomas vocais. Observou-se associação estatisticamente significativa entre carga horária semanal e perfil dermatoglífico.

ABSTRACT Purpose To investigate the association between the dermatoglyphic profile and the vocal condition of teachers at a public higher education institution. Methods 49 professors participated in the study. After signing the Informed Consent Form, the following instruments were used: sociodemographic questionnaire and Voice Disorder Screening Index (ITDV). Fingerprints were collected using the Integrated Biometric Watson Mini scanner and analysis performed using the Cummins and Midlo protocol. The results were presented in absolute frequency. The Chi-Square Test was performed, with a significance level of 5%, to verify the association of ITDV vocal symptoms with a dermatoglyphic profile. This study was approved by the Research Ethics Committee of a public higher education institution under protocol number 3,372.226. Results There was a prevalence of females among the university professors studied. As for the classification of the dermatoglyphic profile , most had an anaerobic profile. There was a statistically significant association only between dermatoglyphic profile and weekly workload. Conclusion Most subjects with an anaerobic profile had more frequency of vocal symptoms. There was a statistically significant association between weekly working hours and dermatoglyphic profile.

Revisión sistemática entre dermatoglifia dactilar y fuerza en el deporte a nivel mundial / Systematic review between fingerprint dermatoglyphics and strength in sport worldwide

RESUMEN La Dermatoglifia ha sido utilizada como herramienta para identificar la relación de esta con las capacidades físicas dentro de diferentes tipos de disciplinas deportivas. El presente documento tuvo como objetivo, identificar los hallazgos de investigaciones a nivel mundial, mostrando los resultados existentes entre los dermatoglifos y la capacidad de la fuerza en el rendimiento deportivo. Método: la búsqueda incluye publicaciones en revistas indexadas en los idiomas inglés, portugués y español. Se utilizaron las siguientes bases de datos: Scopus, Scielo, Redalyc, Pubmed, Sportdiscus, Science Direct y Biblioteca Regional de Salud, para la búsqueda de información se definieron varias palabras clave. Se realizó la búsqueda y luego la revisión, donde se identificaron 56 artículos, de los cuales seis cumplieron con los criterios de inclusión. Resultados y conclusiones: se evidenció que la mayor parte de investigaciones son casos y controles, algunos con altos niveles de sesgo por eso su clasificación fue de 2+ y 3 (Escala SIGN). Los resultados en esta revisión sustentan la relación entre la predominancia del patrón de Presilla y el desarrollo de la fuerza sin discriminar tipo de deporte, género y edad de los practicantes, país de procedencia, composición corporal o características genéticas.

ABSTRACT Dermatoglyphics have been used as a tool to identify its relationship with physical capacities within different types of sports disciplines. The present document aimed to identify research findings worldwide, showing the existing results between dermatoglyphics and the force capacity in sports performance. Method: The search includes publications in indexed journals in the English, Portuguese and Spanish languages. The following databases were used: Scopus, Scielo, Redalyc, Pubmed, Sportdiscus, Science Direct and Regional Health Library, for the information search several key words were defined. The search and then the review were carried out, where 56 articles were identified, of which 6 met the inclusion criteria. Results and conclusions: It was evidenced that most of the investigations are cases and controls, some with high levels of bias, which is why their classification was 2+ and 3 (SIGN Scale). The results in this review support the relationship between the predominance of the Clip pattern and the development of strength without discriminating type of sport, gender and age of the practitioners, country of origin, body composition or genetic characteristics.

Dermatoglifia y fuerza muscular en deportistas de baloncesto universitario / Dermatoglyphics and muscle strength in college basketball players / Dermatoglifia e força muscular em atletas de basquete universitári

RESUMEN El baloncesto es un deporte que requiere capacidades físicas para su desenvolvimiento en cualquier nivel de competencia; la fuerza es uno de los parámetros a evaluar que más exactitud precisa y que puede ayudar a llevar al deportista a su máximo potencial, por esto el objetivo del estudio fue determinar la relación entre las variables dermatoglifia y fuerza muscular en las posiciones de juego del baloncesto universitario, teniendo en cuenta el perfil antropométrico, en jugadores (mujeres y hombres) entre los 17 y 23 años. La muestra fue con 15 atletas de la selección de baloncesto, donde se evaluaron variables dermatoglificas (metodología propuesta por Cummins & Midlo, 1942), medidas antropométricas (la báscula InBody 770 y tallímetro SECA), posición de juego de cada individuo y test de fuerza muscular (T-force, modelo TF-100). Se encontró que la variable de dermatoglifia que más correlación (alta y moderada) tuvo con la prueba de fuerza muscular fueron los Arcos y dentro de este se encontraban los Postes, quienes en esta posición de juego mostraron mayor relación (r= 0,525 p= 0,045). Se demostró que, puede encontrar un lazo entre dos variables como dermatoglifia y fuerza muscular, sin embargo, es importante contar con una muestra más amplia y discriminarla por género, para así tener mayor exactitud.

ABSTRACT Basketball is a sport that requires physical abilities for its development at any level of competition; strength is an evaluated parameter that is more accurate than others and that can help to take the athlete to their maximum potential. For this reason, the objective of this study is to determine the relationship between the dermatoglyphics and muscle strength variables in university basketball playing positions, taking into account the anthropometric profile, in players (women and men) between 17 and 23 years old. The sample consisted of 15 athletes from the basketball team, where dermatoglyphic variables (methodology proposed by Cummins & Midlo, 1942), anthropometric measurements (the InBody 770 scale and SECA height rod), playing position of each individual, and muscle strength test (T-force, model TF-100) were evaluated. The dermatoglyphics variable that had the most correlation (high and moderate) with the muscle strength test were the arches, and within these, were the posts, who, in this playing position, showed the greatest relationship (r = 0.525 p = 0.045). It was shown that you can find a link between two variables such as dermatoglyphics and muscle strength, however, it is important to have a larger sample and discriminate it by gender, in order to have a higher accuracy.

SUMÁRIO O basquete é um esporte que requer habilidades físicas para seu desenvolvimento em qualquer nível de competição; a força é um dos parâmetros a serem avaliados mais precisos e que podem ajudar a levar o atleta ao seu potencial máximo; por esse motivo, o do estudo foi determinar a relação entre as variáveis dermatoglíficas e a força muscular nas posições de jogo de basquete de universidade, considerando o perfil antropométrico, em jogadores (mulheres e homens) entre 17 e 23 anos de idade. A amostra foi composta por 15 atletas do time de basquete, onde variáveis dermatoglíficas (metodologia proposta por Cummins & Midlo, 1942), medidas antropométricas (escala InBody 770 e estadiômetro SECA), posição de jogo de cada indivíduo e teste de força muscular (força T, modelo TF-100). Para análise estatística, foi realizado no software SPSS versão 22, com tendência central (média e desvio padrão). Verificou-se que a variável dermatoglyphic que teve a maior correlação (alta e moderada) com o teste de força muscular foram os Arcos e dentro deste foram os posts, que nesta posição de jogo apresentaram a maior relação (r = 0,525 p = 0,045). Foi demonstrado que, se é possível encontrar um vínculo entre duas variáveis, como dermatoglifos e força muscular, é importante ter uma amostra maior e discriminá-la por sexo, a fim de obter maior precisão.

Huellas dactilares: origen, usos y desafíos que genera la incapacidad para su registro / Fingerprints: origin, uses and challenges in the face of its verification failure

Considerando que las huellas dactilares son impresiones de las crestas epidérmicas de los dedos con un patrón único, irrepetible y permanente, estas son la base del método biométrico más empleado en la actualidad. Entre sus diversos usos destaca la identificación para múltiples actividades como acceder al trabajo o a teléfonos celulares, la operación de cuentas bancarias, las investigaciones criminales, etcétera. La ausencia o deterioro de las crestas epidérmicas, denominada adermatoglifia, impide la identificación por biometría dactilar. La adermatoglifia se origina por múltiples causas, incluyendo las enfermedades dermatológicas, lesiones traumáticas de los dedos, denervación, envejecimiento, quimioterapia, entre otras. Abordamos brevemente el origen, usos y sistemas para el registro de las huellas dactilares. El objetivo principal es enfatizar la existencia de personas con incapacidad para registrar sus huellas, una condición relevante por el riesgo potencial de discriminación, especialmente cuando el registro de las huellas es obligatorio.

Considering that fingerprints are impressions of the epidermal ridges of the fingers with a unique, unrepeatable, and permanent pattern, they are the basis of the biometric identification method most used today. Among its various uses stand out identification for multiple activities such as authentication to access work and cell phones, operation of bank accounts, criminal investigations, etc. The absence or deterioration of the epidermal ridges, called adermatoglyphia, prevents identification by finger biometrics. Adermatoglyphia originates from multiple causes, including several skin diseases, traumatic injuries of the fingers, denervation, aging, chemotherapy, among others. The origin, uses, and systems for fingerprints verification are briefly addressed here. The main objective is to emphasize the existence of people with fingerprint verification failure, a relevant condition due to the potential risk of discrimination, especially when fingerprint verification is mandatory.