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1.
Br J Nurs ; 33(7): S18-S26, 2024 Apr 04.
Artigo em Inglês | MEDLINE | ID: mdl-38578942

RESUMO

Occasionally, the administration of intravenous (IV) therapies can go wrong. Infiltration or extravasation is a complication when a drug or IV therapy leaks into the tissues surrounding the vascular access device. Extravasation can cause serious and often life-changing injuries. Extravasation is often associated with systemic anti-cancer therapy but non-chemotherapy drugs have been reported as having a greater risk of serious complications. This study outlines the first UK Infusion unit evaluation of the ivWatch infusion monitoring device which was undertaken from August 2023 to January 2024. Out of 2254 infusions monitored with ivWatch, the device prevented 122 cases of infiltration and extravasation from causing any harm to the patient, corresponding to a 5.4% 'check IV' notification rate.


Assuntos
Cateterismo Periférico , Cuidados de Enfermagem , Dispositivos de Acesso Vascular , Humanos , Infusões Intravenosas , Extravasamento de Materiais Terapêuticos e Diagnósticos , Dispositivos de Acesso Vascular/efeitos adversos , Cateterismo Periférico/efeitos adversos
2.
Crit Rev Oncol Hematol ; 196: 104277, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38492760

RESUMO

BACKGROUND: Patients with cancer can expect to receive numerous invasive vascular access procedures for intravenous therapy and clinical diagnostics. Due to the increased incidence and prevalence of cancer globally there will be significantly more people who require first-line intravenous chemotherapy over the next ten years. METHODS: Our objective was to determine the types of evidence that exist for the vascular access device (VAD) type for the delivery of systemic anti-cancer therapy (SACT) in cancer patients. We used JBI scoping review methodology to identify the types of VADs used for SACT and with a specific search strategy included articles from 2012-2022 published in the English language. We identify (i) type of VADs used for SACT delivery (ii) the type of insertion and post-insertion complications (iii) the geographical location and clinical environment (iv) and whether VAD choice impacts on quality of life (QOL). Findings were presented using the PAGER framework. MAIN FINDINGS: Our search strategy identified 10,390 titles, of these, 5318 duplicates were removed. The remaining 5072 sources were screened for eligibility, 240 articles met the inclusion criteria. The most common design include retrospective study designs (n = 91) followed by prospective study designs (n = 31). We found 28 interventional studies with 21 registered in a clinical trial registry and identified no core outcome sets papers specific to VAD for SACT. The most prevalent publications were those that featured two or more VAD types (n = 70), followed by tunnelled intravenous VADs (n = 67). Of 38 unique complications identified, the most frequent catheter related complication was catheter related thrombosis (n = 178, 74%), followed by infection (n = 170, 71%). The county where the most publications originated from was China (n = 62) with one randomized controlled multicenter study from a comprehensive cancer centre. Of the thirty three studies that included QOL we found 4 which reported on body image. No QOL measurement tools specific to the process of SACT administration via VAD are available INTERPRETATION: Our findings suggest a systematic review and meta-analysis of VAD use for intravenous SACT can be considered. However, the development of a core outcome set for SACT should be prioritised. Funding for high quality programs of research for VAD in cancer are needed. Comprehensive cancer centres should lead this research agenda.


Assuntos
Neoplasias , Dispositivos de Acesso Vascular , Humanos , Qualidade de Vida , Estudos Prospectivos , Estudos Retrospectivos , Neoplasias/tratamento farmacológico , Dispositivos de Acesso Vascular/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto , Estudos Multicêntricos como Assunto
5.
ANZ J Surg ; 93(6): 1532-1535, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36772890

RESUMO

BACKGROUND: Accurate placement of central venous access devices is important to avoid complications such as infection, thrombosis and migration. This audit aims to determine if there is a difference in complication rates and accuracy of tip position between two different intravenous jugular (IVJ) port device insertion techniques: fixation of port first (PF) versus tip first (TF). METHODS: Patients who underwent port device insertions from 2019 to 2021 at the Cairns Hospital were identified from the Australia Vascular Audit database. The primary outcome of accurate catheter tip placement (based on radiological criteria), secondary outcomes of line infection, thrombosis and other outcomes such as removal rates were gathered and compared between the 2 groups of port first (PF) versus tip first (TF) insertion. RESULTS: Two-hundred and twenty-seven patients underwent port device insertions during the period of interest. 98 (43.2%) patients had a PF insertion technique and 129 (56.8%) had a TF insertion technique. In the PF group, 81.6% (P < 0.05) of lines were accurately placed compared to 69.8% (P < 0.05) in the TF group. The line related thrombosis rate was 1% (P < 0.05) in the PF group compared to 6.2% (P < 0.05) in the TF group. Rate of line infections in the PF group was 5.1% (P = 0.92) compared to 6.2% (P = 0.92) in the TF group. CONCLUSION: The port first technique for IVJ port device placement was associated with higher accuracy and lower thrombosis rates and this was statistically significant. Further studies should involve larger multicentre populations to compare results between practitioners.


Assuntos
Cateterismo Venoso Central , Trombose , Dispositivos de Acesso Vascular , Humanos , Dispositivos de Acesso Vascular/efeitos adversos , Trombose/epidemiologia , Trombose/etiologia , Trombose/prevenção & controle , Remoção de Dispositivo/efeitos adversos , Catéteres/efeitos adversos , Cateteres de Demora/efeitos adversos , Estudos Retrospectivos
6.
J Vasc Access ; 24(3): 502-506, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-34396820

RESUMO

Regular flushing and locking of totally implantable venous access devices (TIVADs) is recommended to maintain their patency when not in use. In this case report, a 73-year-old male patient received radical resection for rectal carcinoma in January 2010. A TIVAD was implanted in 2014 and a total of 12 rounds of chemotherapy of FOLFIRI was completed in 2015. During the period from 2015 to 2020, the patient never used or conducted the monthly infusion port flushing because of the inconvenience, the COVID-19 pandemic, and so on. On 18th April 2020, the patient was admitted to the radiotherapy department of Yiwu Central Hospital. The nurse evaluated the TIVAD upon admission, finding that the skin around the reservoir was normal without any sign of infection as erythema or induration of the skin overlying the implantable port but there was intraluminal occlusion of the devices. In order to re-access the catheter, discussion of a MDT was performed and several days of unremitting efforts were tried. Gratifyingly, the patient's port was re-accessed successfully without any adverse reactions. This is a rare infusion port that has not been used and maintained for 5 years. For the port that has not been used and maintained for a long time up to 5 years, the medical staff should not give up easily. During the COVID-19 pandemic, prolonging the flushing interval of TIVADs can be an optimal clinical strategy without negative outcomes.


Assuntos
COVID-19 , Cateterismo Venoso Central , Dispositivos de Acesso Vascular , Masculino , Humanos , Idoso , Pandemias , Cateteres de Demora/efeitos adversos , Fatores de Tempo , Dispositivos de Acesso Vascular/efeitos adversos , Cateterismo Venoso Central/efeitos adversos
7.
São Paulo; s.n; 2023. 25 p.
Tese em Português | ColecionaSUS, SMS-SP, HSPM-Producao, SMS-SP | ID: biblio-1531246

RESUMO

Introdução: Os ports são cada vez mais aceitos no meio médico e por pacientes. Por ser um dispositivo totalmente implantável, requer menores cuidados locais, diminuindo a possibilidade de infecção ou outras complicações inerentes aos acessos centrais de longa duração. Levando-se em conta o risco das complicações, faz-se necessário analisar a prevalência de complicações após inserção dos ports, a fim de avaliar a eficácia e segurança do procedimento e identificar possíveis falhas do processo. Objetivo: Avaliar a prevalência de complicações após inserção de acessos venosos centrais totalmente implantáveis pela equipe de cirurgia vascular. Método: O estudo foi realizado na enfermaria e ambulatório da cirurgia vascular do Hospital do Servidor Público Municipal ­ SP, e incluiu pacientes atendidos no período de agosto de 2022 a agosto de 2023. Resultados: A amostra deste estudo foi constituída por 62 pacientes oncológicos, sendo 17 do sexo masculino (27%) e 45 do sexo feminino (73%). A comorbidade mais prevalente foi a Hipertensão Arterial Sistêmica isolada ou associada a outras doenças (40,3%, 25 pacientes). A neoplasia mais frequente foi o adenocarcinoma de colo em 14 pacientes (22,6%). Quanto ao acesso, a veia jugular interna direita foi a mais utilizada (50 pacientes, totalizando 80,6%). Quanto às complicações, estas estiveram ausentes em 56 pacientes (90,3%). Desconexão de cateter foi observada em 1 paciente (1,6%), hematoma infectado em 1 (1,6%), hematoma local em 1 (1,6%), hematoma em pós-operatório imediato em 1 (1,6%), infecção em 1 (1,6%), e trombose de veia jugular interna direita em 1 (1,6%). Em 60 pacientes não houve dificuldade de manuseio (96,8%), e em 5 pacientes o dispositivo necessitou ser retirado (8,1%). No total ocorreram 10 óbitos (16,1%) enquanto 52 pacientes permaneceram vivos após a avaliação (83,9%). Conclusão: A prevalência de complicações relacionadas à inserção de cateter em nossa amostra foi bastante reduzida, tendo sido identificadas em apenas 6 pacientes (9,7% do total). Desconexão de cateter, hematoma infectado, hematoma local, hematoma em pós-operatório imediato, infecção e trombose de veia jugular direita foram identificadas cada uma em um único paciente. Palavras-chave: Cirurgia Vascular. Portocath. Cateter Venoso Central. Complicações.


Assuntos
Humanos , Masculino , Feminino , Tratamento Farmacológico/instrumentação , Dispositivos de Acesso Vascular , Dispositivos de Acesso Vascular/efeitos adversos
9.
Langenbecks Arch Surg ; 407(3): 1257-1262, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35257222

RESUMO

PURPOSE: A totally implantable vascular access port (TIVAP) is commonly required in cancer patients. Possible adverse events after TIVAP implantation include surgical site infection (SSI) and port-related bacteremia. This study examined whether adhesive surgical drapes can reduce the risk of SSI. METHODS: A total of 100 mostly cancer patients were randomized into two groups before undergoing TIVAP implantation by surgical cut-down. In one group, an adhesive, non-impregnated drape was applied to the skin prior to incision, while the control group underwent surgery without a drape. Swabs were taken from the surgical site and sent for microbiologic testing. SSI rates were compared between groups. RESULTS: No SSI occurred within 30 days after surgery. In each group, two patients died. There were 5 complications (port thrombosis, port dislocation, two cases of pneumothorax, skin allergy), all in the intervention group (p = 0.056). Using the incision drape prolonged procedure time by + 5 min (95% CI - 1 to + 10, p = 0.125). Microbiologic swab testing failed to detect any effect of the incision drape. CONCLUSIONS: Plastic adhesive skin drapes may be unnecessary in cancer patients who undergo surgical implantation of a TIVAP.


Assuntos
Neoplasias , Campos Cirúrgicos , Dispositivos de Acesso Vascular , Adesivos , Humanos , Projetos Piloto , Plásticos , Campos Cirúrgicos/efeitos adversos , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Dispositivos de Acesso Vascular/efeitos adversos
10.
J Pediatr Surg ; 57(2): 224-228, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34903357

RESUMO

BACKGROUND: Retained intravascular catheter fragments (RICF) are a rare complication of implantable vascular access device (IVAD) removal for which there is limited understanding of aetiology. There is a varied approach to management among the currently published literature. AIMS: The aim of this study was to establish incidence, risk factors, and outcomes for RICF after attempted removal of IVADs. METHODS: A single institution retrospective review was undertaken of individuals ≤ 25 years undergoing removal of IVADs from October 2014 to June 2019. Risk factors for RICF were explored using univariable logistic and Cox regression analysis. RESULTS: Six cases of RICF were identified among 654 line removal episodes (0.92% (95% CI 0.37-2%)) in patients aged 6-17 years (median 11, IQR 6-15 years). The main risk factor for RICF at removal was found to be line duration (OR 3.5/year, 95% CI 2.1-5.84, p < 0.0001). No RICFs occurred in lines indwelling for < 3 years. Five children with RICF ≤ 16 years were discussed with a paediatric cardiothoracic centre, and all were left in situ with 4 remaining asymptomatic. One had the fragment tip extruded through a wound, which required trimming. The other (17 years of age) developed an infected sinus for which partial removal with open excision followed by full removal with endovascular snare retrieval was performed by the adult vascular surgeons. CONCLUSION: IVADs in-situ for longer than a three-year period are at greatest risk of RICF upon removal. Management with transfixion of line fragments to surrounding muscle seems prudent while invasive attempts at retrieval appear unwarranted.


Assuntos
Cateterismo Venoso Central , Dispositivos de Acesso Vascular , Adolescente , Adulto , Cateterismo Venoso Central/efeitos adversos , Cateteres de Demora/efeitos adversos , Criança , Remoção de Dispositivo , Humanos , Incidência , Estudos Retrospectivos , Fatores de Risco , Dispositivos de Acesso Vascular/efeitos adversos
11.
J. vasc. bras ; 21: e20210199, 2022. graf
Artigo em Inglês | LILACS | ID: biblio-1375804

RESUMO

Abstract Co-occurrence of acute limb ischemia (ALI) and arteriovenous fistula (AVF) as a manifestation of inadvertent arterial injury during percutaneous femoral vein dialysis catheter insertion is a rare and dangerous, but preventable complication. Iatrogenic femoral AVF commonly presents late, with leg swelling or high output cardiac failure. However, the co-occurrence of a femoral AVF with both progressive leg swelling, and acute thromboembolism has not been previously reported. We report the case of an iatrogenic femoral AVF with superficial femoral artery (SFA) thrombosis and distal embolism in a 53-year-old female who underwent percutaneous femoral access for temporary hemodialysis. Both the SFA and AVF were managed with open surgical repair.


Resumo A coocorrência de isquemia aguda de membro (IAM) e fístula arteriovenosa (FAV) como uma manifestação de lesão arterial inadvertida durante a inserção de cateter para hemodiálise por via femoral percutânea é uma complicação rara e perigosa, porém evitável. A FAV femoral iatrogênica geralmente tem apresentação tardia, com edema dos membros inferiores ou insuficiência cardíaca de alto débito. No entanto, a coocorrência de FAV femoral com edema progressivo dos membros inferiores e tromboembolismo agudo não foi previamente relatada. Relatamos o caso de uma FAV femoral iatrogênica com trombose da artéria femoral superficial (AFS) e embolia distal em uma paciente do sexo feminino, 53 anos, submetida à acesso femoral percutâneo para hemodiálise temporária. Tanto a AFS quanto a FAV foram manejadas com reparo cirúrgico aberto.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Fístula Arteriovenosa/complicações , Artéria Femoral , Dispositivos de Acesso Vascular/efeitos adversos , Isquemia Crônica Crítica de Membro/complicações , Trombose/cirurgia , Cateterismo Venoso Central/efeitos adversos , Fístula Arteriovenosa/cirurgia , Diálise Renal , Veia Femoral
12.
J. vasc. bras ; 21: e20210189, 2022. tab, graf
Artigo em Português | LILACS | ID: biblio-1375809

RESUMO

Resumo O cateter totalmente implantável (CTI) é utilizado na administração da quimioterapia. Em menos de 1% dos casos de complicação, pode ocorrer migração do CTI para quimioterapia para a circulação sistêmica. O objetivo deste estudo foi descrever um caso de migração do CTI para a veia hepática. Uma paciente do sexo feminino, de 44 anos de idade, teve diagnóstico de câncer de mama com indicação de quimioterapia neoadjuvante. Realizou-se a implantação de cateter port-a-cath. Durante o procedimento de punção do cateter, houve retorno normal de sangue, e foi realizada infusão de soro fisiológico. Em seguida, houve um aumento de volume no local do port e não retorno de sangue à aspiração. A radiografia de tórax mostrou embolização do cateter em topografia hepática. Retirou-se o cateter pela técnica do laço (sem complicações), e a paciente recebeu alta no dia seguinte. Possíveis alterações no funcionamento do CTI devem chamar atenção da equipe responsável.


Abstract A totally implantable venous access port (TIVAP) is used for chemotherapy administration. Venous port migration to the systemic circulation occurs in less than 1% of complications. The aim of this study is to describe a case of TIVAP migration to the hepatic vein. A 44-year-old female patient with breast cancer was prescribed neoadjuvant chemotherapy. A port-a-cath was surgically implanted for chemotherapy. During the port puncture procedure, blood returned normally when aspirated. When the port was first accessed and flushed with saline solution, swelling was observed at the port site and blood could no longer be aspirated. A chest radiography showed catheter embolization in the region of the hepatic vein. The catheter was retrieved using a snare technique (without complications) and the patient was discharged the next day. The care team should be alert to possible TIIVAP malfunction.


Assuntos
Humanos , Feminino , Adulto , Neoplasias da Mama/tratamento farmacológico , Migração de Corpo Estranho/diagnóstico por imagem , Dispositivos de Acesso Vascular/efeitos adversos , Veias Hepáticas/diagnóstico por imagem , Migração de Corpo Estranho/terapia , Terapia Neoadjuvante/instrumentação , Remoção de Dispositivo/métodos
13.
Sultan Qaboos Univ Med J ; 21(1): e103-e109, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33777430

RESUMO

OBJECTIVES: Totally implantable central venous access ports (port-a-caths) are increasingly used for the safe administration of chemotherapy; however, their use is associated with complications. This study reviews patterns of complications, reasons for premature removal and the duration of the use of port-a-caths in patients receiving cancer treatment at Sultan Qaboos University Hospital (SQUH) and compares the infection rate with the literature and the researchers' experiences. METHODS: This retrospective follow-up study included patients who had received cancer treatment through a port-a-cath and were admitted to SQUH between January 2007 and April 2019. Demographic features, underlying diagnosis, clinical stage, treatment, duration of use and the cause of premature removal of the port-a-cath were recorded. RESULTS: A total of 516 port-a-caths were inserted in 482 cancer patients. The majority of devices were implanted by interventional radiologists (n = 459; 89.0%) and the right internal jugular vein was most frequently accessed (n = 396; 76.7%). The mean indwelling time of a port-a-cath was 288 days (range: 3-1,872 days) for patients with complications and 550 days (range: 7-3,123 days) for patients without complications. Port-a-cath-related infection was the main complication (n = 63; 12.2%). Patient age, gender, treatment intent, underlying diagnosis, clinical stage, chemotherapy regimen, number of treatment courses, operator implanting the port, the type of micro-organism isolated from the port-a-cath and body mass index were significant factors affecting catheter indwelling time (P <0.05). On multivariate analysis, however, none of the factors was found to be significant. CONCLUSION: Infection was the most common complication necessitating port-a-cath removal. The infection rate was much lower than the researchers' previous experience and compares favorably with several published reports.


Assuntos
Antineoplásicos/administração & dosagem , Infecções Relacionadas a Cateter/etiologia , Cateterismo Venoso Central/efeitos adversos , Veias Jugulares/cirurgia , Neoplasias/tratamento farmacológico , Sepse/etiologia , Dispositivos de Acesso Vascular/efeitos adversos , Antineoplásicos/uso terapêutico , Feminino , Seguimentos , Hospitais Universitários , Humanos , Masculino , Omã , Infecções Relacionadas à Prótese/etiologia , Estudos Retrospectivos , Dispositivos de Acesso Vascular/microbiologia
14.
J Cardiovasc Med (Hagerstown) ; 22(4): 237-245, 2021 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-33633038

RESUMO

The current narrative review provides an update of available knowledge on venous access techniques for cardiac implantable electronic device implantation, with a focus on axillary vein puncture. Lower procedure-related and lead-related complications have been reported with extrathoracic vein puncture techniques compared with intrathoracic accesses. In particular, extrathoracic lead access through the axillary vein seems to be associated with lower complication incidence than subclavian vein puncture and higher success rate than cephalic vein cutdown. In literature, many techniques have been described for axillary vein access. The use of contrast venography-guided puncture has facilitated the diffusion of the axillary vein approach for device implantation. Venography may be particularly useful in specific demographic and clinical device implantation contexts. Ultrasound-guided or microwire-guided vascular access for lead positioning can be considered a valid alternative to venography, although current applications for axillary vein puncture need further evaluations.


Assuntos
Arritmias Cardíacas/terapia , Veia Axilar , Cateterismo Periférico , Implantação de Prótese , Punções , Veia Axilar/diagnóstico por imagem , Veia Axilar/cirurgia , Cateterismo Periférico/instrumentação , Cateterismo Periférico/métodos , Humanos , Marca-Passo Artificial , Implantação de Prótese/efeitos adversos , Implantação de Prótese/métodos , Punções/efeitos adversos , Punções/instrumentação , Punções/métodos , Cirurgia Assistida por Computador/métodos , Dispositivos de Acesso Vascular/efeitos adversos
15.
Nephrol Dial Transplant ; 36(2): 275-280, 2021 01 25.
Artigo em Inglês | MEDLINE | ID: mdl-31665436

RESUMO

BACKGROUND: There is controversial evidence on whether arteriovenous access (AVA) placement may protect renal function and hence should be considered in the timing of access placement. This study aimed to investigate the association between AVA placement and estimated glomerular filtration rate (eGFR) decline as compared with the placement of a peritoneal dialysis catheter (PDC) at a similar time point. METHODS: We studied a cohort of 744 pre-dialysis patients in Stockholm, Sweden, who underwent surgery for AVA or PDC between 2006 and 2012. Data on comorbidity, medication and laboratory measures were collected 100 days before and after surgery. Patients were followed until dialysis start, death or 100 days, whichever came first. The primary outcome was difference in eGFR decline after AVA surgery compared with PDC. Decline in eGFR was estimated through linear mixed models with random intercept and slope, before and after surgery. RESULTS: There were 435 AVA and 309 PDC patients. The AVA patients had higher eGFR (8.1 mL/min/1.73 m2 versus 7.0 mL/min/1.73 m2) and less rapid eGFR decline before surgery (-5.6 mL/min/1.73 m2/year compared with -6.7 mL/min/1.73 m2/year for PDC). We found no difference in eGFR decline after surgery in AVA patients compared with PDC patients [AVA progressed 0.26 (95% confidence interval -0.88 to 0.35) mL/min/1.73 m2/year faster after surgery compared with PDC]. CONCLUSIONS: There was no significant difference in eGFR decline after placement of an AVA compared with a PDC. Both forms of access were associated with reduced eGFR decline in our population. The need for dialysis remains the main determinant for timing of access surgery.


Assuntos
Derivação Arteriovenosa Cirúrgica/efeitos adversos , Cateterismo/efeitos adversos , Falência Renal Crônica/patologia , Insuficiência Renal Crônica/cirurgia , Dispositivos de Acesso Vascular/efeitos adversos , Idoso , Estudos de Coortes , Feminino , Taxa de Filtração Glomerular , Humanos , Falência Renal Crônica/epidemiologia , Falência Renal Crônica/etiologia , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Suécia/epidemiologia
16.
Ann R Coll Surg Engl ; 103(1): e23-e25, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32969714

RESUMO

We present an 84-year-old man with erosion of the chemotherapy port on his chest wall. He had a history of colorectal cancer with liver metastases more than 20 years ago, when he underwent right hemicolectomy and liver resection. A hepatic artery infusion catheter was placed for targeted administration of chemotherapy for the liver metastases. Imaging showed the catheter had migrated into the small bowel lumen. We considered the best approach for removing the migrated catheter - either remove the catheter and accept the likelihood of a low-volume enterocutaneous fistula that may self-resolve, or explore the enterocutaneous tract with a view to small bowel resection. We discuss the advantages and disadvantages here.


Assuntos
Antineoplásicos/administração & dosagem , Cateteres de Demora/efeitos adversos , Migração de Corpo Estranho/diagnóstico , Fístula Intestinal/etiologia , Dispositivos de Acesso Vascular/efeitos adversos , Idoso de 80 Anos ou mais , Antibacterianos/administração & dosagem , Colectomia , Neoplasias do Colo/patologia , Neoplasias do Colo/terapia , Desbridamento , Remoção de Dispositivo , Migração de Corpo Estranho/etiologia , Migração de Corpo Estranho/terapia , Hepatectomia , Artéria Hepática , Humanos , Fístula Intestinal/terapia , Neoplasias Hepáticas/secundário , Neoplasias Hepáticas/terapia , Masculino , Resultado do Tratamento
17.
J Pediatr Surg ; 56(1): 183-186, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33131779

RESUMO

BACKGROUND/PURPOSE: Long-term central venous access is a safe and common procedure in children. However, complications with devices are a reality. Smaller children are thought to have a higher rate of complication after port placement, and some surgeons avoid placing ports with an arbitrary weight cutoff out of concern for surgical site morbidity. METHODS: We performed a multi-institutional retrospective review of 500 patients less than 5 years of age undergoing port placement at three large volume children's hospitals from 2014 to 2018. Patients were divided by weight greater than or less than 10 kg at the time of insertion. Statistical analysis was performed to evaluate for differences in outcomes between the two groups. RESULTS: The majority of ports were placed for chemotherapy access (71.8%). Other indications included long-term infusions (18.8%) and difficult chronic IV access (9.4%). Of the 500 charts reviewed, 110 (22%) experienced some documented complication (28.9% <10 kg, 20.6% >10 kg, p = 0.096). There were no differences between the two groups in terms of the type or timing of complications. Overall, 16.3% of ports required removal prior to the end of therapy owing to a complication. Complication rate per day with the port in place was not different between the two groups (<10 kg: 0.68 complications/1000 port-days vs >10 kg 0.44 complications/1000 port-days, p = 0.068). CONCLUSION: Weight less than 10 kg was not associated with a significantly higher incidence of any type of port complication in our cohort. This suggests that concern for complications should not exclude children less than 10 kg from port placement. TYPE OF STUDY: Multi-institutional retrospective review. LEVEL OF EVIDENCE: Level III.


Assuntos
Cateterismo Venoso Central , Cateteres Venosos Centrais , Peso Corporal , Cateterismo Venoso Central/efeitos adversos , Cateteres de Demora/efeitos adversos , Cateteres Venosos Centrais/efeitos adversos , Pré-Escolar , Feminino , Humanos , Incidência , Lactente , Masculino , Estudos Retrospectivos , Fatores de Risco , Dispositivos de Acesso Vascular/efeitos adversos
18.
Eur J Appl Physiol ; 120(11): 2525-2532, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32857185

RESUMO

PURPOSE: Animal studies have shown that endothelial denudation abolishes vasodilation in response to increased shear stress. Interestingly, shear-mediated dilation has been reported to be reduced, but not abolished, in coronary artery disease (CAD) patients following catheterization. However, it is not known whether this resulted from a priori endothelial dysfunction in this diseased population. In this study, we evaluated shear-mediated dilation following catheterization in healthy young men. METHODS: Twenty-six (age: 24.4 ± 3.8 years, BMI: 24.3 ± 2.8 kg m-2, VO2peak: 50.5 ± 8.8 ml/kg/min) healthy males underwent unilateral transradial catheterization. Shear-mediated dilation of both radial arteries was measured using flow-mediated dilation (FMD) pre-, and 7 days post-catheterization. RESULTS: FMD was reduced in the catheterized arm [9.3 ± 4.1% to 4.3 ± 4.1% (P < 0.001)] post-catheterization, whereas no change was observed in the control arm [8.4 ± 3.8% to 7.3 ± 3.8% (P = 0.168)]. FMD was completely abolished in the catheterized arm in five participants. Baseline diameter (P = 0.001) and peak diameter during FMD (P = 0.035) were increased in the catheterized arm 7 days post-catheterization (baseline: 2.3 ± 0.3 to 2.6 ± 0.2 mm, P < 0.001, peak: 2.5 ± 0.3 to 2.7 ± 0.3 mm, P = 0.001), with no change in the control arm (baseline: 2.3 ± 0.3 to 2.3 ± 0.3 mm, P = 0.288, peak: 2.5 ± 0.3 to 2.5 ± 0.3 mm, P = 0.608). CONCLUSION: This is the first study in young healthy individuals with intact a priori endothelial function to provide evidence of impaired shear-mediated dilation following catheterization. When combined with earlier studies in CAD patients, our data suggest the catheterization impairs artery function in humans.


Assuntos
Cateterismo/efeitos adversos , Artéria Radial/fisiologia , Dispositivos de Acesso Vascular/efeitos adversos , Vasodilatação , Adulto , Cateterismo/métodos , Endotélio Vascular/fisiologia , Voluntários Saudáveis , Humanos , Masculino
19.
World J Surg Oncol ; 18(1): 134, 2020 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-32560722

RESUMO

BACKGROUND: Implanted vascular access devices play an essential role in the management of pediatric patients. The objectives of this study were to assess our experience with port-a-cath insertion in pediatric patients, report its complications, and compare open versus percutaneous approaches. METHODS: We performed a retrospective cohort study, including 568 patients who underwent port-a-cath insertion between 2013 and 2019 in our center. We grouped the patients according to the technique of insertion into two groups: group 1 (n = 168) included patients who had the open approach and group 2 (n = 404) included patients who had the percutaneous technique. (p < 0.001). RESULTS: Patients in group 1 were younger (4.10 ± 3.45 years) compared to patients in group 2 (5.47 ± 3.85 years). The main indications of insertion were hematological malignancy 57.74% (n = 328), solid organ malignancy 25.18% (n = 143), pure hematological diseases 5.46% (n = 31), metabolic diseases 2.64% (n = 15), and others for poor vascular access 8.8% (n = 50). The most common site for insertion in group 1 was the left external jugular (n = 136; 82.98%) and the left subclavian in group 2 (n = 203; 50.25%). Two hundred and two patients had a central line before catheter insertion (36.6%). Complications during insertion were comparable between both groups (p = 0.427). The catheter got stuck in 6 patients; all required additional incision and two needed venotomy. The most common reason to remove the catheter was the completion of the treatment (63.69% and 61.14%, in groups 1 and 2, respectively). The duration of the catheter was comparable between the two groups (13.14 ± 14.76 vs. 14.44 ± 14.04 months in group 1 vs.2; p = 0.327). CONCLUSIONS: Open and percutaneous port-a-cath insertions are safe in children with chronic diseases. Port-a-cath improved patients' management, and complications are infrequent. The most common complications are infection and catheter malfunction, which can be managed without catheter removal in some patients.


Assuntos
Cateterismo Venoso Central/instrumentação , Cateteres de Demora/normas , Complicações Pós-Operatórias/etiologia , Centros de Atenção Terciária/organização & administração , Dispositivos de Acesso Vascular/normas , Cateterismo Venoso Central/efeitos adversos , Cateteres de Demora/efeitos adversos , Pré-Escolar , Feminino , Humanos , Masculino , Prognóstico , Estudos Retrospectivos , Resultado do Tratamento , Dispositivos de Acesso Vascular/efeitos adversos
20.
BMC Nephrol ; 21(1): 231, 2020 06 18.
Artigo em Inglês | MEDLINE | ID: mdl-32552698

RESUMO

BACKGROUND: Haemodialysis patients have a high mortality rate. Part of this can be attributed to vascular access complications. Large retrospective studies have shown a higher mortality in patients dialysed with a catheter, which is mostly ascribed to infectious complications. Since we observe very little infectious complications in our haemodialysis patients, the aim of our study was to assess if we could still detect a difference in survival according to vascular access type. METHODS: Patients that started chronic haemodialysis treatment between 1/1/2007 and 31/12/2016 at the 'Universitair Ziekenhuis Brussel' were retrospectively studied. The time to death was studied as a function of the two main vascular access types using survival analysis, considering the type of vascular access at the initiation of dialysis or as time varying, and accounting for the available baseline characteristics. RESULTS: Of 374 patients 309 (82.6%) initiated haemodialysis with a catheter, while 65 patients initiated with an arteriovenous access. Vascular access type during follow-up did not change in 74% of all patients. A Kaplan Meier plot did not suggest a survival dependent on the vascular access type at start. An extended cox proportional hazard analysis showed that vascular access type was not independently correlated with mortality. However, age, history of congestive heart failure and active cancer at initiation of dialysis were independently associated with mortality. CONCLUSIONS: In this retrospective cohort study, haemodialysis vascular access type was not independently correlated with patient survival, even after taking into account change of vascular access over time.


Assuntos
Derivação Arteriovenosa Cirúrgica/efeitos adversos , Cateterismo Venoso Central/efeitos adversos , Falência Renal Crônica/terapia , Diálise Renal/mortalidade , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Feminino , Humanos , Estimativa de Kaplan-Meier , Falência Renal Crônica/mortalidade , Masculino , Pessoa de Meia-Idade , Diálise Renal/métodos , Estudos Retrospectivos , Dispositivos de Acesso Vascular/efeitos adversos
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