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1.
Cutis ; 114(2): 65-66, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-39298767

RESUMO

Surgical excision of the pigmented nail matrix followed by histopathologic examination is a common procedure aimed at managing longitudinal melanonychia (LM). In some cases, use of a standard scalpel can pose challenges, particularly if the width of the pigmented matrix lesion is narrow. We explore an alternative and effective tool-the customized dermal curette.


Assuntos
Doenças da Unha , Neoplasias Cutâneas , Humanos , Doenças da Unha/cirurgia , Doenças da Unha/patologia , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia , Curetagem/métodos , Unhas/cirurgia , Unhas/patologia , Procedimentos Cirúrgicos Dermatológicos/métodos
3.
S D Med ; 77(1): 37-41, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38986147

RESUMO

Glomus tumors are rare vascular hamartomas most commonly found in the subungual region of the fingers. They present with a classic triad of paroxysmal pain, point tenderness, and cold sensitivity. The diagnosis is often missed for several years due to under recognition of this condition. A 42-year-old female presented with a several year history of pain in the middle finger when it was struck or exposed to cold. She had point tenderness on the fingernail, and increased curvature of the nail. Magnetic Resonance Imaging (MRI) revealed a 7mm subungual glomus tumor. The tumor was surgically excised via a transungual approach, resulting in complete relief of her pain. Glomus tumors are diagnosed clinically based on the presence of classic symptoms and positive provocative tests. These tests include point tenderness on palpation and pain when ice is placed on the digit. MRI imaging can be used when the diagnosis is unclear or to localize the tumor prior to surgery. Increased awareness of this condition among physicians could reduce the time to diagnosis and treatment.


Assuntos
Dedos , Tumor Glômico , Imageamento por Ressonância Magnética , Humanos , Tumor Glômico/diagnóstico , Tumor Glômico/complicações , Tumor Glômico/cirurgia , Feminino , Adulto , Imageamento por Ressonância Magnética/métodos , Dor/etiologia , Dor/diagnóstico , Doenças da Unha/diagnóstico , Doenças da Unha/cirurgia , Doenças da Unha/diagnóstico por imagem , Doenças da Unha/etiologia
5.
J Dermatol ; 51(8): 1117-1119, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38874495

RESUMO

Recently, functional or preservative surgery has been preferred for nail unit melanoma; however, complete resection of the nail unit, particularly the matrix, is challenging because of its complex structure. This study aims to measure the distance of important nail structures through ultrasonography. Herein, 14 patients without nail deformity were included. The length from the nail cuticle to the distal interphalangeal joint (distance X), to the attachment part of the extensor muscle (distance A), to the median proximal end of the nail matrix (distance B), and to the lateral proximal end of the nail matrix (distance C) were measured. In the axial plane, the length from the highest point of the nail plate to the bottom of the distal phalanx (distance Y) and to the lateral tip of the nail plate (distance D) were measured. On the first fingernail, third fingernail, first toenail, and third toenail, the mean ratio A:X, ratio B:X, ratio C:X, and ratio D:Y were 78.6%, 44.3%, 57.2%, 40.1%, and 84.6%; 55.9%, 64.9%, 40.2%, and 66.4%; 35.6%, 50.8%, 34.3%, and 81.9%; and 57.2%, 59.6%, and 31.7%, respectively. Nail units are often invisible to the naked eye; thus, this study will help identify the approximate scope of excision.


Assuntos
Melanoma , Doenças da Unha , Unhas , Neoplasias Cutâneas , Ultrassonografia , Humanos , Feminino , Masculino , Melanoma/cirurgia , Melanoma/diagnóstico por imagem , Melanoma/patologia , Unhas/diagnóstico por imagem , Unhas/cirurgia , Pessoa de Meia-Idade , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/diagnóstico por imagem , Neoplasias Cutâneas/patologia , Doenças da Unha/cirurgia , Doenças da Unha/diagnóstico por imagem , Doenças da Unha/patologia , Idoso , Adulto
6.
Hand Surg Rehabil ; 43S: 101526, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38879227

RESUMO

Longitudinal melanonychia (LM) is a pigmented band extending from the matrix to the distal edge of a nail. It is caused by increased production of melanin within the matrix, and integration into the nail plate. The origin of this production is usually benign, due to activation, hyperplasia or proliferation of melanocytes normally present in the matrix. In some cases, however, LM is the manifestation of a subungual melanoma, the diagnosis of which must be made early. Biographical, clinical and dermoscopic criteria make it possible to suspect melanoma and decide whether to perform biopsy. None of these criteria, however, are specific and definitive diagnosis requires pathologic examination of a matrix biopsy. The biopsy technique should enable reliable histological study while limiting the risk of secondary nail dystrophy. Initial resection should ideally involve the entire lesion. Complete elevation of the nail plate enables the lesion to be precisely located. Lesions up to 3 mm can be removed by longitudinal resection biopsies without significant sequelae. In more extensive lesions, incision or tangential ("shave") biopsy can be performed without impairing prognosis. In clinical presentations strongly suggestive of melanoma, immediate complete resection of the entire nail unit may be proposed.


Assuntos
Melanoma , Doenças da Unha , Neoplasias Cutâneas , Humanos , Biópsia , Melanoma/cirurgia , Melanoma/patologia , Melanoma/diagnóstico , Doenças da Unha/cirurgia , Doenças da Unha/patologia , Doenças da Unha/diagnóstico , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia
7.
Hand Surg Rehabil ; 43S: 101527, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38879228

RESUMO

Congenital nail disorders are an uncommon presenting symptom which can be difficult to diagnose and manage. Nail diseases in the pediatric population differ from those in adults in terms of diagnosis, approach and management. In most cases, they do not require treatment and resolve with growth. Physicians need to be able to recognize them, to reassure the parents. The most frequently encountered pathologies associated with nail disorder are syndactyly, acrosyndactyly, symbrachydactyly, macrodactyly, Wassel I thumb duplication, Kirner's deformity and congenital onychodysplasia of the index finger. Treatment usually consists in surgical correction of the deformity. Nail malformation can also be an aspect of a systemic disease. It may provide a clue for screening, and should not be overlooked. Nail conditions can be the first sign of nail-patella syndrome, ectodermal dysplasia, dyskeratosis congenita, epidermolysis bullosa, pachyonychia congenita or lung disease. Medical treatment is therefore discussed on a case-by-case basis.


Assuntos
Unhas Malformadas , Humanos , Doenças da Unha/congênito , Doenças da Unha/cirurgia , Displasia Ectodérmica/cirurgia , Displasia Ectodérmica/diagnóstico
8.
Hand Surg Rehabil ; 43S: 101655, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38879230

RESUMO

Mucous cyst is a benign but recurrent lesion. It is located on the dorsal surface of the digital extremity between the distal interphalangeal joint and the base of the nail. The nail is often affected by the cyst because of its topographical proximity. Nail plate deformity may even be the first obvious abnormality indicating the presence of a small mucous cyst or subungual cyst. Mucous cyst is associated with osteoarthritis of the joint, osteophytes probably being the main contributing factor. Surgical treatment by joint debridement and cyst removal is the most effective way of preventing recurrence.


Assuntos
Desbridamento , Humanos , Mucocele/cirurgia , Doenças da Unha/cirurgia , Cistos/cirurgia , Dedos/cirurgia , Dedos/anormalidades , Articulações dos Dedos/cirurgia
10.
Artigo em Inglês | MEDLINE | ID: mdl-38753531

RESUMO

Bony outgrowths of the distal phalanx of the great toe have been described in the literature but rarely. These subungual bony outgrowths can be caused by subungual exostosis or subungual osteochondromas. Both of these abnormalities are bony outgrowths with differences in the cartilage cap wherein the exostoses have fibrocartilage, and osteochondromas have hyaline cartilage. The subungual exostosis and osteochondroma that are protruding present symptoms of pain, redness, and deformed nail bed, whereas the nonprotruding osteochondromas have only a lump as the presenting symptom. In both conditions, excision of the lesion and curettage of the base helps prevent a recurrence. Curettage at the end of the excision of the bony outgrowth is required to avoid recurrence. After excision, the specimen should be sent for histopathologic examination to differentiate between the exostosis and osteochondromas, which are underreported in subungual locations, and to rule out malignant transformation. We present a 13-year-old girl with an isolated subungual nonprotruding exostosis of the great toe that was treated by excisional biopsy. The histopathologic examination confirmed it as osteochondroma, which is underreported.


Assuntos
Neoplasias Ósseas , Exostose , Doenças da Unha , Osteocondroma , Humanos , Neoplasias Ósseas/cirurgia , Neoplasias Ósseas/patologia , Neoplasias Ósseas/diagnóstico , Neoplasias Ósseas/diagnóstico por imagem , Feminino , Osteocondroma/cirurgia , Osteocondroma/diagnóstico por imagem , Osteocondroma/patologia , Osteocondroma/diagnóstico , Exostose/cirurgia , Exostose/diagnóstico , Adolescente , Doenças da Unha/cirurgia , Doenças da Unha/patologia , Doenças da Unha/diagnóstico , Hallux/cirurgia , Dedos do Pé/cirurgia
11.
J Eur Acad Dermatol Venereol ; 38(10): 1988-1996, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-38717320

RESUMO

Dermoscopy of the nail unit (onychoscopy) is a method which allows for non-invasive observation of the nail structures, increasing the accuracy of clinical diagnosis. Currently, it is used in evaluation of both inflammatory and neoplastic conditions of the nail unit. However, in contrast to the skin, the anatomy of the nail unit prevents direct observation of nail bed or nail matrix structure during classic onychoscopy. Intra-operative onychoscopy is a variant of the technique which uses direct visualization of the nail unit structures after nail plate avulsion. The aim of this systematic review was to summarize the current state of knowledge on intra-operative onychoscopy. The MEDLINE, EMBASE and Cochrane databases were systematically searched in January 2024. All types of study designs assessing intra-operative dermoscopy of the nail unit were included in this study. The risk of bias in included studies was assessed using the Joanna Briggs Institute critical appraisal tools. The qualitative synthesis of 19 studies totalling a number of 218 cases in 217 patients included the following entities: melanoma, nevus, hypermelanosis (melanocytic activation), melanocytic hyperplasia, melanophages accumulation, squamous cell carcinoma, glomus tumour, lichen planus, onychomatricoma, onychomycosis and subungual exostosis. The main limitation of the study was a relatively low number of identified studies, most with low levels of evidence. Intra-operative onychoscopy does not replace histologic examination, though it may be useful in determining the modality of surgical diagnostic procedures.


Assuntos
Dermoscopia , Doenças da Unha , Humanos , Dermoscopia/métodos , Cuidados Intraoperatórios , Doenças da Unha/patologia , Doenças da Unha/diagnóstico por imagem , Doenças da Unha/cirurgia , Unhas/diagnóstico por imagem , Unhas/patologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia
12.
J Hand Surg Asian Pac Vol ; 29(3): 240-247, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38726497

RESUMO

Background: Glomus tumour is a painful small tumour of the glomus body commonly located under the nail bed. The aim of this study is to evaluate the correlation of clinical diagnosis with MRI findings, determine the prevalence of the tumour at different subungual locations and determine the differences in outcomes (if any) between a longitudinal and a transverse nail bed incision for excision of the tumour. Methods: This retrospective study of 56 subungual glomus tumour was conducted from May 2010 to December 2021. Data with regard to gender, age at presentation, digit involved, presenting symptoms, duration of symptoms, clinical signs, need for MRI, anatomical location, surgical approach (longitudinal versus transverse), histopathology result, period of follow-up and complications were recorded. Results: All 56 (100%) patients presented with classic triad of symptoms. The average duration of symptoms was 52.9 months (range: 3-204 months). Eleven (20%) tumours were in the sterile matrix, 38 (68%) at the junction of sterile and germinal matrix and 7 (12%) in the germinal matrix. The tumours were excised through the longitudinal incision in 31 (55.3%) patients and transverse incision in 25 (44.7%). One (1.8%) tumour was intraosseous that was diagnosed intraoperatively and excised successfully. Average follow-up was 35.4 months (range: 6-120 months). There was no difference in outcomes (pain or nail deformity) between the two incisions. One patient (1.8%) has persistent pain that was due to a missed satellite lesion in the same digit. This was excised later with resolution of symptoms. There were no recurrences and all patients were cured after excision of tumour. Conclusions: Diagnosis of glomus tumour is usually clinical, and most are located at junction of sterile and germinal matrix. Tumour can be excised either by longitudinal or transverse nail bed incisions without any change of treatment outcome. Level of Evidence: Level IV (Therapeutic).


Assuntos
Tumor Glômico , Imageamento por Ressonância Magnética , Doenças da Unha , Humanos , Tumor Glômico/cirurgia , Tumor Glômico/patologia , Tumor Glômico/diagnóstico por imagem , Tumor Glômico/diagnóstico , Masculino , Feminino , Doenças da Unha/cirurgia , Doenças da Unha/patologia , Doenças da Unha/diagnóstico por imagem , Doenças da Unha/diagnóstico , Adulto , Estudos Retrospectivos , Pessoa de Meia-Idade , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/diagnóstico por imagem , Neoplasias Cutâneas/diagnóstico , Adulto Jovem , Idoso , Adolescente , Resultado do Tratamento
13.
Hand Surg Rehabil ; 43S: 101711, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38679322
14.
Ann Plast Surg ; 92(4S Suppl 2): S87-S90, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38556653

RESUMO

HYPOTHESIS: The natural history of pediatric melanonychia and the necessity of biopsy for ruling out melanoma are debated in the literature. We hypothesize that there is a low rate of malignant nail pathology among pediatric patients undergoing nail bed biopsy for melanonychia. METHODS: We performed a retrospective chart review of 54 pediatric patients (age <18 years) at a single institution who presented with melanonychia and underwent nail bed biopsy from 2007 to 2022. Data points collected included patient demographics, medical history, physical exam findings, pathology reports, and clinical photos. Univariate and multivariate analyses were performed to assess for risk factors associated with high-risk pathology findings. RESULTS: The average age of melanonychia onset was 5.5 years (SD 4.4). The average age of first biopsy was 7.8 years (SD 4.3). On physical exam, 27 patients had at least four features concerning for melanoma (asymmetry, border irregularity, color heterogeneity, diameter > 1/3 of nail, evolving color, evolving diameter, Hutchinson's sign). The most common pathology diagnoses were melanocytic nevus (35%), atypical intraepidermal melanocytic proliferation (AIMP) with benign features (24%), subungual lentigo (22%), and AIMP with concerning features (17%). There were no cases of melanoma in situ or invasive malignant melanoma. On multivariate regression, the only significant risk factor associated with more concerning pathology (AIMP with concerning features) was the calendar year in which biopsy was performed (coefficient = -0.34, P = 0.016). There was no association between physical exam features and high-risk pathology. Twelve patients had surgical re-excision of the lesion, 6 of which were due to incomplete excision of AIMP with concerning features and 6 of which were due to recurrence. CONCLUSIONS: Our case series did not find any cases of melanoma in situ or malignant melanoma arising from pediatric melanonychia. Atypical intraepidermal melanocytic proliferation with concerning features was associated only with the year in which the biopsy was performed, which may reflect the improved understanding of pediatric melanonychia as often benign despite concerning features on pathology. The decision to perform a nail matrix biopsy in pediatric melanonychia should be based on a collaborative discussion between the patient's parents, dermatologist, and plastic surgeon.


Assuntos
Melanoma , Doenças da Unha , Neoplasias Cutâneas , Criança , Humanos , Pré-Escolar , Adolescente , Melanoma/diagnóstico , Melanoma/cirurgia , Melanoma/patologia , Estudos Retrospectivos , Doenças da Unha/diagnóstico , Doenças da Unha/cirurgia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia , Unhas , Melanoma Maligno Cutâneo
16.
Medicine (Baltimore) ; 103(11): e37398, 2024 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-38489706

RESUMO

INTRODUCTION: This case report describes the diagnosis of a glomus tumor in the second toe of a 38-year-old female, followed by surgical treatment utilizing a transungual approach to preserve the nail. This study highlights the diagnostic challenges and surgical strategies to treat such tumors while preserving nail integrity. PATIENT CONCERNS: Pain occurred once a week, but over time, it increased, and just before seeking medical attention, she experienced pain more than 5 times a day. The pain worsened when cold water touched her toe. DIAGNOSIS: We observed a slight hump indicating nail plate deformity, and the patient exhibited severe pinpoint tenderness (positive Love test) in the affected area. Color duplex ultrasound was performed for further investigation, revealing a hypervascular hypoechoic nodule measuring 0.5 cm in size at the nail bed of the right second toe. INTERVENTION: The surgery was performed under digital nerve block anesthesia using a modified transungual nail-preserving approach for the excision of the glomus tumor. OUTCOMES: The pain that was reported prior to the surgery has improved postoperatively, and the recovery has been uneventful without any other complication. CONCLUSION: This paper provides a comprehensive examination of a rare glomus tumor in the second toe, elucidating both diagnostic intricacies and treatment modalities. It emphasizes the dual necessity of achieving total tumor excision while also considering aesthetic outcomes. The insights presented herein are intended to serve as valuable guidance for clinicians confronted with similar clinical scenarios, underlining the delicate interplay between effective tumor management and the preservation of cosmetic integrity.


Assuntos
Tumor Glômico , Doenças da Unha , Neoplasias Cutâneas , Humanos , Feminino , Adulto , Tumor Glômico/diagnóstico por imagem , Tumor Glômico/cirurgia , Neoplasias Cutâneas/cirurgia , Unhas/cirurgia , Doenças da Unha/diagnóstico , Doenças da Unha/cirurgia , Dedos do Pé/cirurgia , Dedos do Pé/patologia , Dor
17.
J Dtsch Dermatol Ges ; 22(4): 522-529, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38459639

RESUMO

BACKGROUND: One of the areas of care in dermatosurgery is the surgical treatment of diseases of the nail organ. Side effects and complications after nail surgery were investigated by telephone follow-up (TFU), and its suitability for postoperative monitoring and consultation was assessed. PATIENTS AND METHODS: All patients who underwent nail surgery at the Department of Dermatology at the Ludwigshafen City Hospital from October 2019 to December 2021 in outpatient setting were contacted by telephone on the second to third postoperative day and questioned in a standardized manner about postoperative complaints and counselled if necessary. RESULTS: A total of 100 cases were followed up. The most common procedures performed were phenol matricectomy (41%), nail avulsion (16%), and nail matrix biopsies (9%). 50% and 21% of patients reported pain on the day of the procedure and the day after surgery, respectively. After nail avulsion, pain was statistically significantly more frequently reported on the day following the procedure and pain medication was statistically significantly more frequently required (p  =  0.002). Serious adverse events did not occur after nail surgery. 10% of the respondents raised specific questions and needed counseling by TFU. CONCLUSIONS: All nail surgeries were well tolerated in the outpatient setting. Pain was the most common side effect, although only half of all patients reported pain on the day of surgery and only 21% on the day after the procedure. The TFU proved to be an effective and practical as well as easy to establish method for postoperative follow-up and consultation after outpatient nail surgery.


Assuntos
Doenças da Unha , Pacientes Ambulatoriais , Humanos , Seguimentos , Estudos Retrospectivos , Doenças da Unha/cirurgia , Dor , Telefone
18.
Am J Surg ; 231: 79-85, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38492992

RESUMO

BACKGROUND: Subungual melanoma (SUM) is a rare tumor with historically poor outcomes. Thus, the benefit of proximal versus distal amputation in SUM remains unclear. METHODS: We performed a retrospective review of our prospectively-maintained institutional melanoma database, including SUM and non-subungual acral melanoma (AM) patients who underwent sentinel lymph node biopsy (SLNB) between 1999 and 2022. All SUMs had distal joint or proximal amputations. Primary endpoints were overall survival (OS) and recurrence free survival (RFS). Kaplan-Meier estimates, and Cox univariate and multivariate analyses were performed. Tests were repeated on propensity score matched (PSM) populations in a 2:1 ratio. RESULTS: 123 patients underwent resection with SLNB for SUM (n â€‹= â€‹27) and AM (n â€‹= â€‹96). Median follow-up was 9.2 years. Unadjusted median OS was 149.1 months for AM and 198.1 months for SUM. In the PSM comparison, median OS and RFS remained comparable between SUM and AM (149.5 months versus 198.1 months; p â€‹= â€‹0.612). Sentinel node positivity was associated with significantly worse overall survival outcome (Hazard Ratio 5.49; CI (1.59-18.97), p â€‹= â€‹0.007). In the PSM population, male sex was also associated with a significant hazard of death (HR 3.00, CI (1.03-8.71), p â€‹= â€‹0.043). Proximal amputations were associated with significantly worse OS (p â€‹< â€‹0.002) and RFS (p â€‹< â€‹0.01) compared to distal amputations in SUM. CONCLUSION: SUM was well-treated with distal amputations, and had better OS and RFS compared to SUM treated with proximal amputations. Sentinel lymph node status is an important prognostic factor for SUMs and AMs. SUMs can be treated similarly to AMs with comparably good long-term outcomes.


Assuntos
Melanoma , Doenças da Unha , Linfonodo Sentinela , Neoplasias Cutâneas , Humanos , Masculino , Melanoma/patologia , Biópsia de Linfonodo Sentinela , Prognóstico , Taxa de Sobrevida , Neoplasias Cutâneas/patologia , Linfonodo Sentinela/patologia , Estudos Retrospectivos , Doenças da Unha/patologia , Doenças da Unha/cirurgia
20.
Hand Surg Rehabil ; 43S: 101635, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38367768

RESUMO

Injuries to the fingertips are the most frequently occurring damage to the hand. The nail is an exceptional structure within the human body that offers both stability and protection, as well as the ability to perform fine and precise movements. Nail dystrophies are numerous, post-traumatic, post-infection or even degenerative. They raise many difficulties for the treating hand surgeon. Which anatomical structure is dystrophic? Is there any secondary fungal superinfection to be treated before surgery? Among the various techniques proposed, which one will help to improve my patient as a complete cure is rarer than partial failures. In this chapter we have chosen to describe the surgical techniques, their difficulties and drawbacks, that are available for the most frequent dystrophies that the hand surgeons may treat.


Assuntos
Doenças da Unha , Humanos , Doenças da Unha/cirurgia , Traumatismos dos Dedos/cirurgia , Unhas/cirurgia , Unhas/lesões , Unhas Malformadas/cirurgia
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