Assuntos
Injúria Renal Aguda/diagnóstico , Linfadenopatia/diagnóstico , Neutropenia/diagnóstico , Esplenomegalia/diagnóstico , Injúria Renal Aguda/sangue , Injúria Renal Aguda/urina , Biópsia , Pré-Escolar , Creatinina/sangue , Diagnóstico Diferencial , Feminino , Ferritinas/sangue , Humanos , Rim/patologia , Linfadenopatia/sangue , Linfadenopatia/urina , Neutropenia/sangue , Neutropenia/urina , Esplenomegalia/sangue , Esplenomegalia/urina , Ureia/sangueRESUMO
Urinalysis by the IITP method in 115 patients with lymphatic tumors has shown that in half of them, BJ protein can be identified. The authors' and reported data evidence the lack of BJ proteinuria in normal people and in patients afflicted with other diseases. Since BJ proteinuria was demonstrable with the minimal tumorous mass in successfully treated patients with CLL and LC, the IITP method was used for excluding a morphologically undemonstrable lymphatic tumor in 23 patients with rheumatic diseases, AIHA, and splenomegaly of obscure genesis. Based on the identified BJ protein secretion in the urine, the diagnoses of CLL (I), LC (2), and LS (I) were proved in 4 cases. Later on these diagnoses were supported by the cytologic and histologic findings.
Assuntos
Proteína de Bence Jones/urina , Leucemia Linfocítica Crônica de Células B/urina , Linfoma não Hodgkin/urina , Adulto , Contraimunoeletroforese , Diagnóstico Diferencial , Feminino , Humanos , Cadeias Leves de Imunoglobulina/análise , Leucemia Linfocítica Crônica de Células B/diagnóstico , Linfoma não Hodgkin/diagnóstico , Masculino , Pessoa de Meia-Idade , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/urina , Esplenomegalia/diagnóstico , Esplenomegalia/urinaRESUMO
Leucine aminopeptidase activity and total protein concentration was estimated in the fresh early morning sample of urine of twenty five normal adult subjects, twenty four cases with active urinary bilharziasis, eleven cases with active intestinal bilharziasis, ten cases with mixed bilharzial infection (urinary and intestinal), fourteen bilharzial cases with clinical hepatosplenomegaly of bilharzial etiology, thirteen bilharzial cases with clinical hepatosplenomegaly and ascites, and twelve cases with cancer bladder of bilharzial etiology. It was found that there is a significant increase in LAP activity in the urine of all groups of patients studied. Again this increase ran parallel to the course of the disease in bilharzial cases. Urine protein concentration was found to be increased significantly in all groups of bilharzial cases studied with the highest value in urine of patients with cancer bladder of bilharzial etiology. However no direct correlation was found between urinary LAP level and protein concentration either within the individual cases or within the different groups.
Assuntos
Leucil Aminopeptidase/urina , Esquistossomose/enzimologia , Adulto , Hepatomegalia/enzimologia , Hepatomegalia/urina , Humanos , Enteropatias Parasitárias/enzimologia , Enteropatias Parasitárias/urina , Masculino , Proteinúria , Esplenomegalia/enzimologia , Esplenomegalia/urina , Neoplasias da Bexiga Urinária/enzimologia , Neoplasias da Bexiga Urinária/urina , UrinaRESUMO
Arylsulfatase A and B in urine have been estimated in 18 normal subjects and 50 bilharziasis patients. The bilharziasis patients were divided into two groups according to the type of infeciton. Those with bilharziasis haematobian type of infection and those with the bilharziasis mansoni type. Each group was further subdivided into subgroups according to the severity and progress of the disease. The activities of arylsulfatase A and B were significantly elevated in all the groups of patients studied and it is evident that there is a progressive increase with the progress of the disease in both types of bilharziasis infections (the haematobian and mansoni types). Liver dysfunction consequent of bilharzial infestation appears to take part in the mechanism of induction of the bilharzial bladder cancer.