RESUMO
OBJECTIVE: This review aims to summarize the latest application of optical coherence tomography (OCT) in oral mucosal diseases, promoting an accurate and earlier diagnosis of such disorders, which are difficult to be differentiated. SUBJECTIVE AND METHODS: References on the application of OCT in oral mucosal diseases were mainly obtained from PubMed, Embase, Web of Science and Scopus databases, using the keywords: "optical coherence tomography and 'oral mucosa/oral cancers/oral potentially malignant diseases/oral lichen planus/oral leukoplakia/oral erythroplakia/discoid lupus erythematosus/oral autoimmune bullous diseases/oral ulcers/erythema multiforme/oral mucositis'". RESULTS: It is found that OCT is showing a promising application potential in the early detection, diagnosis, differential diagnosis, monitoring of oral cancer and oral dysplastic lesions, as well as the delineation of tumor margins. OCT is also playing an increasingly important role in the diagnosis of oral potentially malignant disorders, oral mucosal bullous diseases, oral ulcerative diseases, erythema multiforme, and the early detection of oral mucositis. CONCLUSION: Optical coherence tomography, as a novel optical technique featured by real-time, noninvasive, dynamic and high-resolution imaging, is of great use to serve as an adjunct tool for the diagnosis, differential diagnosis, monitoring and therapy evaluation of oral mucosal diseases.
Assuntos
Líquen Plano Bucal , Doenças da Boca , Mucosa Bucal , Neoplasias Bucais , Tomografia de Coerência Óptica , Humanos , Tomografia de Coerência Óptica/métodos , Doenças da Boca/diagnóstico por imagem , Doenças da Boca/diagnóstico , Mucosa Bucal/diagnóstico por imagem , Mucosa Bucal/patologia , Neoplasias Bucais/diagnóstico por imagem , Líquen Plano Bucal/diagnóstico por imagem , Líquen Plano Bucal/diagnóstico , Diagnóstico Diferencial , Eritroplasia/diagnóstico por imagem , Estomatite/diagnóstico por imagem , Estomatite/diagnóstico , Leucoplasia Oral/diagnóstico por imagem , Leucoplasia Oral/diagnóstico , Úlceras Orais/diagnóstico por imagem , Eritema Multiforme/diagnóstico por imagem , Eritema Multiforme/diagnóstico , Lúpus Eritematoso Discoide/diagnóstico por imagemRESUMO
Radiation induced oral mucositis (RIOM) is a common and debilitating complication of radiation therapy for head and neck cancers. RIOM can lead to oral pain, dysphagia, and reduced oral intake, which can be severe enough to necessitate placement of a feeding tube or utilization of total parenteral nutrition. When severe, RIOM can cause premature termination of radiation therapy and can alter treatment plans leading to suboptimal treatment doses. While patient reporting of RIOM symptoms has been the gold standard of documenting RIOM progression, little has been described in the radiology literature concerning the typical imaging findings of RIOM. Herein, we review the pathophysiology and clinical presentation that underlies the development of RIOM with illustrative cases to highlight the relevant imaging findings related to RIOM for the practicing radiologist.
Assuntos
Neoplasias de Cabeça e Pescoço , Mucosite , Lesões por Radiação , Estomatite , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Neoplasias de Cabeça e Pescoço/radioterapia , Humanos , Mucosite/diagnóstico por imagem , Mucosite/etiologia , Lesões por Radiação/diagnóstico por imagem , Radiologistas , Estomatite/diagnóstico por imagem , Estomatite/etiologiaAssuntos
Estomatite/diagnóstico por imagem , Doenças da Língua/diagnóstico por imagem , Adulto , Inibidores de Calcineurina/uso terapêutico , Feminino , Gengiva/diagnóstico por imagem , Gengiva/patologia , Glucocorticoides/uso terapêutico , Humanos , Mucosa Bucal/diagnóstico por imagem , Mucosa Bucal/patologia , Fotografação , Estomatite/tratamento farmacológico , Estomatite/patologia , Língua/diagnóstico por imagem , Língua/patologia , Doenças da Língua/tratamento farmacológico , Doenças da Língua/patologia , Resultado do TratamentoRESUMO
Mucositis is the limiting toxicity of radio(chemo)therapy of head and neck cancer. Diagnostics, prophylaxis and correction of this condition demand new accurate and objective approaches. Here we report on an in vivo longitudinal monitoring of the oral mucosa dynamics in 25 patients during the course of radiotherapy of oropharyngeal and nasopharyngeal cancer using multifunctional optical coherence tomography (OCT). A spectral domain OCT system with a specially-designed oral imaging probe was used. Microvasculature visualization was based on temporal speckle variations of the full complex signal evaluated by high-pass filtering of 3D data along the slow scan axis. Angiographic image quantification demonstrated an increase of the vascular density and total length of capillary-like-vessels before visual signs or clinical symptoms of mucositis occur. Especially significant microvascular changes compared to their initial levels occurred when grade two and three mucositis developed. Further, microvascular reaction was seen to be dose-level dependent. OCT monitoring in radiotherapy offers a non-invasive, convenient, label-free quantifiable structural and functional volumetric imaging method suitable for longitudinal human patient studies, furnishing fundamental radiobiological insights and potentially providing useful feedback data to enable adaptive radiotherapy (ART).
Assuntos
Microvasos/diagnóstico por imagem , Mucosa Bucal/irrigação sanguínea , Mucosa Bucal/diagnóstico por imagem , Tomografia de Coerência Óptica , Adulto , Angiografia/métodos , Relação Dose-Resposta à Radiação , Feminino , Humanos , Masculino , Microcirculação/efeitos da radiação , Microvasos/patologia , Pessoa de Meia-Idade , Mucosa Bucal/patologia , Mucosa Bucal/efeitos da radiação , Neoplasias Nasofaríngeas/complicações , Neoplasias Nasofaríngeas/diagnóstico , Neoplasias Nasofaríngeas/radioterapia , Radioterapia/efeitos adversos , Dosagem Radioterapêutica , Estomatite/diagnóstico por imagem , Estomatite/etiologia , Estomatite/patologia , Tomografia de Coerência Óptica/métodosAssuntos
Carcinoma/diagnóstico , Colite Ulcerativa/complicações , Doenças da Gengiva/diagnóstico , Neoplasias Gengivais/diagnóstico , Estomatite/diagnóstico , Adalimumab/uso terapêutico , Idoso , Anti-Inflamatórios/uso terapêutico , Biópsia , Carcinoma/diagnóstico por imagem , Carcinoma/patologia , Colite Ulcerativa/diagnóstico , Colite Ulcerativa/tratamento farmacológico , Colonoscopia , Diagnóstico Diferencial , Doenças da Gengiva/diagnóstico por imagem , Doenças da Gengiva/etiologia , Doenças da Gengiva/patologia , Neoplasias Gengivais/diagnóstico por imagem , Neoplasias Gengivais/patologia , Humanos , Masculino , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Valor Preditivo dos Testes , Estomatite/diagnóstico por imagem , Estomatite/etiologia , Estomatite/patologia , Resultado do TratamentoRESUMO
BACKGROUND AND OVERVIEW: The aim of this study was to describe the effects of bruxism in peri-implant bone loss 6 years after the placement of a successful implant-supported prosthesis, to describe its treatment, and to propose a differential diagnosis of the lesion. CASE DESCRIPTION: A 62-year-old, nonsmoking, systemically healthy partially edentulous woman received 2 osseointegrated implants in the mandibular left region, which supported a 3-element fixed prosthesis. Six years later, the patient reported the development of bruxism. Clinical examination results indicated bleeding on probing, deepening of the peri-implant sulcus, and marginal soft-tissue overgrowth. Radiographic images suggested peri-implant bone loss. The authors diagnosed the lesion as trauma from occlusion and mucositis. Treatment involved anti-infective therapy and the use of a bite platform, resulting in bone recovery after 10 months. These results were maintained for 4 years. CONCLUSIONS AND PRACTICAL IMPLICATIONS: Considering the existing contradictions in the literature, this case highlights the role of trauma from occlusion in the onset, progression, and treatment of lesions produced by occlusal overload around osseointegrated implants. In addition, it provides clinical background on the outcomes of anti-infective therapy associated with the use of a bite platform in the treatment of combined lesions of mucositis and trauma from occlusion in osseointegrated implants.
Assuntos
Oclusão Dentária Traumática/diagnóstico , Peri-Implantite/diagnóstico , Estomatite/diagnóstico , Bruxismo/complicações , Implantação Dentária Endóssea/efeitos adversos , Oclusão Dentária Traumática/diagnóstico por imagem , Oclusão Dentária Traumática/etiologia , Prótese Dentária Fixada por Implante/efeitos adversos , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade , Peri-Implantite/diagnóstico por imagem , Peri-Implantite/etiologia , Radiografia Dentária , Estomatite/diagnóstico por imagem , Estomatite/etiologiaRESUMO
Mucositis remains a frequent complication of radiotherapy. Low level laser applications are used to accelerate the healing process. This technique is used routinely in our centre. It is performed by delegation by radiotherapists. The conditions of this delegation of tasks are addressed here.
Assuntos
Pessoal Técnico de Saúde , Delegação Vertical de Responsabilidades Profissionais , Terapia com Luz de Baixa Intensidade/efeitos adversos , Mucosa/efeitos da radiação , Tolerância a Radiação , Estomatite/diagnóstico por imagem , Estomatite/prevenção & controle , Humanos , CintilografiaRESUMO
OBJECTIVE: The objective of this study was to correlate changes in computed tomography perfusion (CTP) parameters in the oropharyngeal mucosa following start of radiotherapy (RT) with acute mucositis in head and neck cancer patients. METHODS: Fifteen patients were prospectively evaluated with serial CTP imaging. Computed tomography perfusion studies were obtained before RT; at weeks 2, 4, and 6 during RT; and 6 weeks after completion of RT. RESULTS: At week 2 during RT, mean transition time increased to 13.9% and 261.8% in patients with and without mucositis, respectively (P = 0.024). At week 6 of RT, patients with grade 3 mucositis had a 325.4% increase in blood flow compared with a 58.3% increase in patients with grade 0-2 mucositis (P = 0.039). Mean transition time decreased by 29.9% and increased by 187.4% in patients with grade 3 and grade 0-2 mucositis, respectively (P = 0.025). CONCLUSIONS: Mean transition time and blood flow changes in the oropharyngeal mucosa correlated with the incidence and severity of RT-related mucositis.
Assuntos
Carcinoma de Células Escamosas/radioterapia , Neoplasias Orofaríngeas/radioterapia , Lesões por Radiação/diagnóstico por imagem , Lesões por Radiação/etiologia , Radioterapia Conformacional/efeitos adversos , Estomatite/diagnóstico por imagem , Estomatite/etiologia , Idoso , Carcinoma de Células Escamosas/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Orofaríngeas/complicações , Neoplasias Orofaríngeas/diagnóstico por imagem , Imagem de Perfusão/métodos , Prognóstico , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Estatística como Assunto , Tomografia Computadorizada por Raios X/métodos , Resultado do TratamentoRESUMO
BACKGROUND: Acute oral or pharyngeal infections usually heal under adequate therapy within a few days. Therefore severe regionary or systemic complications are not regularly seen. PATIENTS AND METHODS: We report on 3 patients in whom during or after apparent recovery from a pharyngeal or perioral infection a one-sided painful swelling of the neck associated with fever and leucocytosis developed. RESULTS: Color Doppler sonography (CDS) revealed unilateral thrombosis of the internal jugular vein (IJV) in all cases, whereupon we initiated high-dosed parenteral antibiotic therapy and therapeutic heparinisation. Furthermore, we drained detectable abscess formations. Nonetheless, in one patient fever attacks occurred postoperatively, accompanied by septic-embolic lung infiltrates, corresponding to Lemierre's syndrome. In all cases, we achieved clinical recovery and remission of infection. The course was significantly prolonged in the patient with pulmonary involvement and in this patient no reperfusion of the IJV was achieved. CONCLUSIONS: Even today serious complications may occur unexpectedly in presumed everyday oral or pharyngeal infections. CDS is a suitable procedure to disclose a jugular vein thrombosis (JVT) promptly and non-invasively. Parenteral antibiotic therapy for at least 10 days is usually the therapy of choice for JVT; additional full-heparinisation is controversially discussed in the professional literature. Septic pulmonary embolism following pharyngeal infection and JVT, as described by Lemierre, was associated with a high rate of mortality in the pre-antibiotic era, and even today may be fatal in spite of appropriate and maximal therapy.
Assuntos
Veias Jugulares/diagnóstico por imagem , Síndrome de Lemierre/diagnóstico por imagem , Linfadenite/complicações , Faringite/complicações , Abscesso Retrofaríngeo/complicações , Estomatite/complicações , Tonsilite/complicações , Ultrassonografia Doppler em Cores , Adulto , Antibacterianos/uso terapêutico , Anticoagulantes/uso terapêutico , Terapia Combinada , Diagnóstico Diferencial , Humanos , Síndrome de Lemierre/terapia , Linfadenite/diagnóstico por imagem , Linfadenite/terapia , Masculino , Faringite/diagnóstico por imagem , Faringite/terapia , Embolia Pulmonar/diagnóstico por imagem , Embolia Pulmonar/terapia , Recidiva , Abscesso Retrofaríngeo/diagnóstico por imagem , Abscesso Retrofaríngeo/terapia , Fatores de Risco , Estomatite/diagnóstico por imagem , Estomatite/terapia , Tonsilite/diagnóstico por imagem , Tonsilite/terapia , Adulto JovemAssuntos
Doenças do Gato/cirurgia , Gengivite/veterinária , Estomatite/veterinária , Procedimentos Cirúrgicos Operatórios/veterinária , Animais , Doenças do Gato/diagnóstico por imagem , Gatos , Doença Crônica , Feminino , Gengivite/diagnóstico por imagem , Gengivite/cirurgia , Halitose/etiologia , Halitose/veterinária , Masculino , Radiografia , Estomatite/diagnóstico por imagem , Estomatite/cirurgia , Resultado do TratamentoRESUMO
PURPOSE: We conducted a clinical study to correlate oral cavity dose with clinical mucositis, perform in vivo dosimetry, and determine the feasibility of obtaining buccal mucosal cell samples in patients undergoing head-and-neck radiation therapy. The main objective is to establish a quantitative dose response for clinical oral mucositis. METHODS AND MATERIALS: Twelve patients undergoing radiation therapy for head-and-neck cancer were prospectively studied. Four points were chosen in separate quadrants of the oral cavity. Calculated dose distributions were generated by using AcQPlan and Eclipse treatment planning systems. MOSFET dosimeters were used to measure dose at each sampled point. Each patient underwent buccal sampling for future RNA analysis before and after the first radiation treatment at the four selected points. Clinical and functional mucositis were assessed weekly according to National Cancer Institute Common Toxicity Criteria, Version 3. RESULTS: Maximum and average doses for sampled sites ranged from 7.4-62.3 and 3.0-54.3 Gy, respectively. A cumulative point dose of 39.1 Gy resulted in mucositis for 3 weeks or longer. Mild severity (Grade = 1) and short duration (=1 week) of mucositis were found at cumulative point doses less than 32 Gy. Polymerase chain reaction consistently was able to detect basal levels of two known radiation responsive genes. CONCLUSIONS: In our sample, cumulative doses to the oral cavity of less than 32 Gy were associated with minimal acute mucositis. A dose greater than 39 Gy was associated with longer duration of mucositis. Our technique for sampling buccal mucosa yielded sufficient cells for RNA analysis using polymerase chain reaction.
Assuntos
Neoplasias de Cabeça e Pescoço/radioterapia , Radioterapia Conformacional/efeitos adversos , Estomatite/diagnóstico por imagem , Estomatite/epidemiologia , Actinas/genética , Replicação do DNA/efeitos da radiação , Relação Dose-Resposta à Radiação , Feminino , Humanos , Masculino , Mucosa Bucal/patologia , Mucosa Bucal/efeitos da radiação , Seleção de Pacientes , Reação em Cadeia da Polimerase , RNA/genética , RNA/isolamento & purificação , RNA Ribossômico 18S/genética , Grupos Raciais , Cintilografia , Dosagem RadioterapêuticaRESUMO
PURPOSE: To assess noninvasive optical coherence tomography (OCT) and optical Doppler tomography (ODT) for early detection and evaluation of chemotherapy-induced oral mucositis. EXPERIMENTAL DESIGN: Cheek pouches of 10 Syrian golden hamsters were imaged using OCT/ODT during development of chemotherapy-induced mucositis. I.p. injections of 5-fluorouracil and mechanical irritation induced oral lesions. At 2, 4, 7, and 11 days, one hamster was sacrificed and processed for histopathology. OCT images were visually examined; ODT results were semiquantified. Imaging data were compared with histologic findings. RESULTS: During the development of mucositis, OCT/ODT identified the following events: (a) change in epithelial thickness (beginning on day 2), (b) loss of surface keratinized layer continuity (beginning on day 4), (c) loss of epithelial (day 4 onwards) and submucosal integrity (day 7 onwards), (d) changes in axial blood flow velocity (increased on days 2 and 4; decreased on day 7), and (e) changes in blood vessel size (diameter doubled on day 2; quadrupled on day 4; unchanged on day 7). The semiquantitative imaging-based scoring system identified the severity of mucositis as defined by histopathology. The combination of imaging criteria used allowed for the detection of early, intermediate, and late mucositic changes. Imaging data gave higher scores compared with clinical scores early on, suggesting that the imaging-based diagnostic scoring was more sensitive to early mucositic change than the clinical scoring system. Once mucositis was established, imaging and clinical scores converged. CONCLUSION: OCT/ODT identified chemotherapy-induced oral changes before their clinical manifestation, and the proposed scoring system for oral mucositis was validated for the semiquantification of mucositic change.
Assuntos
Fluoruracila/toxicidade , Estomatite/diagnóstico , Animais , Velocidade do Fluxo Sanguíneo , Cricetinae , Modelos Animais de Doenças , Mesocricetus , Mucosa Bucal/irrigação sanguínea , Mucosa Bucal/patologia , Estomatite/induzido quimicamente , Estomatite/diagnóstico por imagem , Tomografia de Coerência Óptica , UltrassonografiaRESUMO
INTRODUCTION: Oral mucositis is recognised as one of the most debilitating complications of high-dose cytostatic chemotherapy used to prepare for haematopoietic stem cell transplantation (HSCT), but very little is known about oesophageal mucositis, as endoscopy is not routinely performed. MATERIALS AND METHODS: We incorporate the computed tomography (CT) scan in the diagnostic workup of fever during neutropenia to detect evidence of pulmonary complications. This allowed us to evaluate whether mucosal barrier injury to the oesophagus can be determined. We selected 46 patients without oesophageal cancer or immune suppression (controls), who had a normal oesophagus, and measured the mucosal thickness at the upper part (UP), middle part (MP) and lower part (LP) of the oesophagus. Next, we selected 30 patients having a CT scan done for diagnostic purposes within 14 days after HSCT and measured mucosal thickness at the same levels. We also scored oral mucositis and gut toxicity. RESULTS: The mucosal thickness of the UP, MP and LP, respectively, for the controls (mean +/- SD) was 4.1 mm (+/-1.1), 4.2 mm (+/-1.2) and 4.8 mm (+/-1.3), and the corresponding values for the subjects were 5.9 mm (+/-2.2), 5.9 mm (+/-2.0) and 7.7 mm (+/-3.0). Analysis of variance showed statistically significant differences between subjects and controls at all oesophageal levels. All patients suffered from severe oral mucositis at the time. CONCLUSION: Hence, mucosal barrier injury to the oesophagus can be objectively measured using CT scan.
Assuntos
Doenças do Esôfago/diagnóstico por imagem , Esôfago/diagnóstico por imagem , Mucosite/diagnóstico por imagem , Mucosa/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mucosite/induzido quimicamente , Mucosa/lesões , Estomatite/induzido quimicamente , Estomatite/diagnóstico por imagemRESUMO
AIM: The aim of the present experiment was to study peri-implant tissue reactions to lateral static load at implants subjected to experimental mucositis or peri-implantitis. MATERIAL AND METHODS: 5 beagle dogs were used. The mandibular premolars were extracted. After 12 weeks, 3 implants were installed in each quadrant of the mandible. In one side, the implants were designed with a SLA surface and in the contralateral side with a turned surface. A plaque control program was initiated. 12 weeks later, the central and posterior implants were connected with an appliance containing an expansion screw. Cotton ligatures were placed around the neck of the anterior and posterior implants in both sides, and the plaque control measures were terminated. Sixteen weeks later the ligatures were removed. After 8 weeks without ligatures, the expansion screws in both sides were activated. Once every 2 week during a 12-week interval, the screws were reactivated. Thus, the model included 3 different experimental sites of each surface group: group M+L (mucositis+load); group P (peri-implantitis); group P+L (peri-implantitis+load). Fluorochrome labels were injected and standardized radiographs obtained. The animals were sacrificed and block biopsies of all implant sites dissected and prepared for histological analysis. RESULTS: It was demonstrated that the lateral static load failed to induce peri-implant bone loss at implants with mucositis and failed to enhance the bone loss at implants with experimental peri-implantitis. The proportion of bone labels and the bone density in the interface zone were significantly higher in group P+L than in group P. CONCLUSION: It is suggested that a lateral static load with controlled forces may not be detrimental to implants exhibiting mucositis or peri-implantitis.
Assuntos
Implantes Dentários , Mandíbula/fisiopatologia , Periodontite/fisiopatologia , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/etiologia , Perda do Osso Alveolar/patologia , Animais , Dente Pré-Molar/cirurgia , Densidade Óssea/fisiologia , Remodelação Óssea/fisiologia , Placa Dentária/fisiopatologia , Placa Dentária/prevenção & controle , Planejamento de Prótese Dentária , Modelos Animais de Doenças , Cães , Corantes Fluorescentes , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Doenças Mandibulares/diagnóstico por imagem , Doenças Mandibulares/etiologia , Doenças Mandibulares/patologia , Periodontite/diagnóstico por imagem , Periodontite/patologia , Radiografia , Estatística como Assunto , Estomatite/diagnóstico por imagem , Estomatite/patologia , Estomatite/fisiopatologia , Estresse Mecânico , Propriedades de Superfície , Titânio/química , Extração Dentária , Suporte de CargaRESUMO
Mandibular osteomyelitis often is associated with involvement of the masticator space. Assessment of mandibular osteomyelitis should therefore involve assessment of soft tissue involvement of the lesion. The purpose of this study was to clarify the relationship between computed tomography patterns and the presence of inflammation in soft tissues. Thirty-three cases diagnosed with osteomyelitis of the mandible were analyzed radiologically with conventional radiographs and with computed tomography scans. Computed tomography patterns of osteomyelitis were classified into four types, lytic, mixed, sclerotic, and sequestrum patterns. Location, extent of the lesion, and change of the cortical plate were evaluated and compared with conventional radiographic findings. Mixed pattern cases displayed diffuse bone abnormalities, which sometimes were accompanied by cortical plate disruption and periosteal reaction. In addition, most mixed pattern cases showed soft tissue involvement, especially of the masseter muscle. Inflammation of the masseter muscle was found to be related to periosteal reaction and disruption of the buccal cortical plate. The data demonstrate a close interaction between cortical plate disruption and muscle inflammation. The extent of inflammation including soft tissue involvement was better appreciated with computed tomography in osteomyelitis, especially in mixed pattern cases.
Assuntos
Doenças Mandibulares/diagnóstico por imagem , Osteomielite/diagnóstico por imagem , Periostite/diagnóstico por imagem , Adolescente , Adulto , Idoso , Análise de Variância , Fasciite/diagnóstico por imagem , Feminino , Humanos , Masculino , Músculos da Mastigação/diagnóstico por imagem , Pessoa de Meia-Idade , Miosite/diagnóstico por imagem , Parotidite/diagnóstico por imagem , Estomatite/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Filme para Raios XRESUMO
Infections of the uvula are infrequently recognized and have been previously described only in association with group A streptococcal pharyngitis or Haemophilus influenzae type b epiglottitis. Three cases of H influenzae type b bacteremic uvulitis are described. In suspected cases of H influenzae type b uvulitis, a lateral neck radiograph should be performed and parenteral antibiotics initiated.
Assuntos
Infecções por Haemophilus , Estomatite/microbiologia , Úvula/microbiologia , Artrite Infecciosa/microbiologia , Pré-Escolar , Epiglote/diagnóstico por imagem , Feminino , Haemophilus influenzae/isolamento & purificação , Humanos , Lactente , Masculino , Radiografia , Sepse/microbiologia , Estomatite/diagnóstico por imagem , Úvula/diagnóstico por imagemRESUMO
Radionuclide images of hospital patients were examined for abnormal areas within the jaws. Fourteen of 25 subjects studied showed one or more abnormal image areas, most of which were attributable to common dental lesions revealed by oral examinations. The lesions detectable on images included healing bone sites, periodontal and pulpal disease, residual osteitis and irritations caused by ill-fitting dentures.