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1.
Vet Ophthalmol ; 26(1): 12-18, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36509702

RESUMO

PURPOSE: To describe clinical features of non-diabetic canine cataracts with presumed pre-existing posterior capsule rupture (PLCR) and their surgical outcomes. METHODS: Clinical records of 497 non-diabetic canines that underwent elective cataract surgery were reviewed. Twelve canines met the inclusion criteria indicative of PLCR pre-dating surgery. RESULTS: The incidence of presumed pre-existing PLCR was 12/497 (2.4%). Cataracts included were unilateral in 10 out of 12 canines (83.3%) and bilateral in the remaining two (16.7%). Four eyes (28.6%) had clinically detectable pre-operative lens-induced uveitis. The mean age at cataract diagnosis for cases included was 6.6 years, and golden retrievers were the most common breed affected (28.6%). Phacoemulsification surgery was performed at a median time of 110 days (range 17-403 days) after presentation. Pre-existing PLCR was found intra-operatively as a large ellipse spanning the posterior capsule from equator to equator centrally in 12 eyes and peripherally in two eyes. The capsular defect in all eyes with PLCR incorporated a distinct "pseudo-capsule" preventing vitreal presentation and ruling out intraoperative surgeon rupture. Ten eyes (71.4%) received an intraocular lens implant (IOL), and 13 eyes (92.9%) maintained vision throughout a mean follow-up period of 12 months. CONCLUSION: Posterior lens capsule rupture of blunt trauma origin and associated cataract formation, as reported in humans, may also be an infrequent but distinct cause of some cases of non-diabetic canine cataracts. Medical management of phacolytic uveitis and delayed phacoemulsification surgery may be beneficial by allowing time for "pseudo-capsule" development, increasing the likelihood of IOL placement and improved visual outcomes.


Assuntos
Extração de Catarata , Catarata , Doenças do Cão , Traumatismos Oculares , Facoemulsificação , Cápsula Posterior do Cristalino , Animais , Cães , Humanos , Catarata/veterinária , Extração de Catarata/veterinária , Doenças do Cão/diagnóstico , Doenças do Cão/etiologia , Doenças do Cão/cirurgia , Traumatismos Oculares/cirurgia , Traumatismos Oculares/veterinária , Implante de Lente Intraocular/veterinária , Facoemulsificação/veterinária , Cápsula Posterior do Cristalino/lesões , Ruptura/cirurgia , Ruptura/veterinária , Acuidade Visual
2.
Vet Ophthalmol ; 25(5): 316-325, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35239249

RESUMO

OBJECTIVE: To determine the effect of cumulative dissipated energy (CDE) on complications and visual outcome following cataract surgery in dogs. ANIMALS STUDIED: Records of 182 canine eyes that had undergone cataract surgery. PROCEDURES: Retrospective medical record review was conducted on dogs that underwent unilateral or bilateral elective cataract surgery by a single surgeon. Preoperative variables such as age, cataract duration, and pre-existing conditions were recorded. Intraoperative variables such as intraocular lens (IOL) status, phacoemulsification time, average power, irrigation fluid volume, and CDE were recorded. Postoperative complications and visual status at last follow-up were compared to these variables. RESULTS: Eighty-six percent of dogs were visual in one or both eyes at last follow-up (LFU) examination. Median follow-up time was 186 days postoperatively. Eyes that developed glaucoma had a significantly greater mean CDE (77.73 ± 80.11) than eyes that did not develop glaucoma (49.21 ± 38.93). Eyes that remained visual at the LFU examination had a significantly lower mean CDE (48.31 ± 37.14) than eyes that were blind at LFU (82.05 ± 82.73). Significantly lower mean CDEs were found in diabetic eyes, younger eyes, early-operated eyes (<1 month duration), and eyes with preoperative lens-induced uveitis. CONCLUSIONS: Higher CDE may be associated with an increased risk of postoperative glaucoma and loss of vision in dogs. Cumulative dissipated energy may be a useful prognostic indicator for success of canine cataract surgery.


Assuntos
Extração de Catarata , Catarata , Doenças do Cão , Glaucoma , Facoemulsificação , Animais , Catarata/diagnóstico , Catarata/veterinária , Extração de Catarata/efeitos adversos , Extração de Catarata/veterinária , Doenças do Cão/etiologia , Doenças do Cão/cirurgia , Cães , Glaucoma/complicações , Glaucoma/cirurgia , Glaucoma/veterinária , Facoemulsificação/efeitos adversos , Facoemulsificação/veterinária , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/veterinária , Estudos Retrospectivos , Resultado do Tratamento
3.
Vet Ophthalmol ; 24(2): 177-184, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33538086

RESUMO

OBJECTIVE: To report intraoperative findings and complications associated with cataract surgery performed after retinal reattachment surgery (RR) via pars plana vitrectomy (PPV) using perfluoro-n-octane (PFO), laser retinopexy, and silicone oil tamponade in dogs. ANIMALS STUDIED: Retrospective record review of dogs that underwent post-RR cataract surgery. Signalment, time between RR and cataract surgery, type of lens extraction, postoperative visual status, and intra- and postoperative complications were recorded. Cataract formation or progression after RR was categorized as early (≤12 months) or late (>12 months). RESULTS: A total of 36 dogs (41 eyes) were included. Average time between RR and cataract surgery was 665 days (median: 546). Early postoperative incidence of cataracts occurred in 19 eyes (46.3%). Types of lens extraction included phacoemulsification with intraocular lens (86.1%, 31/36 dogs), phacoemulsification alone (11.1%, 4/36 dogs), and intracapsular lens extraction (2.8%, 1/36 dogs). Visual improvement occurred in 95.1% of eyes (39/41) immediately postoperatively. Long term, 93.9% of eyes (31/33) maintained vision at 1 month, 85.2% of eyes (23/27) at 3 months, 77.3% of eyes (17/22) at 6 months, and 60% (12/20) at 12 months postoperatively. The most common postoperative complications were glaucoma (29.3%, 12/41 eyes), corneal ulceration (24.4%, 10/36 eyes), fibrin formation (21.9%, 9/41 eyes), and silicone oil migration into the anterior chamber (19.5%, 8/41 eyes). CONCLUSION: Post-RR cataract surgery should be considered in dogs with vision loss from cataracts after RR. In most eyes, vision was maintained up to 1 year postoperatively.


Assuntos
Extração de Catarata/veterinária , Catarata/veterinária , Doenças do Cão/cirurgia , Descolamento Retiniano/veterinária , Animais , Cães , Feminino , Período Intraoperatório , Masculino , Complicações Pós-Operatórias/veterinária , Descolamento Retiniano/cirurgia , Estudos Retrospectivos , Resultado do Tratamento , Visão Ocular , Vitrectomia/veterinária
4.
Vet Ophthalmol ; 23(5): 872-878, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32813935

RESUMO

PURPOSE: To determine the effect of intrsacameral epinephrine on heart rate, blood pressure, post-operative ocular hypertension, and complications following canine phacoemulsification. PROCEDURES: A prospective, double-blinded, controlled trial was carried out using 30 client-owned dogs undergoing phacoemulsification. Eyes were randomly assigned to a treatment group receiving intracameral (IC) epinephrine (n = 31) or balanced salt solution (n = 25) at the beginning of surgery. Heart rate, post-operative intraocular pressures, and outcomes were compared between treatment groups. RESULTS: No adverse reactions to IC epinephrine or saline were observed. Post-operative ocular hypertension developed at the 2 and/or 4 hours pressure reading in 35% and 46% in the epinephrine and saline groups, respectively (P = .5072). There were 9.7% and 23.1% eyes that developed complications in the IC epinephrine and saline groups, respectively (P = .2373). CONCLUSIONS: Intracameral epinephrine is safe to use, and non-significant decreases in post-operative ocular hypertension and long-term complications were observed.


Assuntos
Extração de Catarata/veterinária , Doenças do Cão/cirurgia , Epinefrina/farmacologia , Glaucoma/veterinária , Midriáticos/farmacologia , Soluções Oftálmicas/farmacologia , Animais , Pressão Sanguínea/efeitos dos fármacos , Cães , Método Duplo-Cego , Epinefrina/administração & dosagem , Feminino , Glaucoma/cirurgia , Frequência Cardíaca/efeitos dos fármacos , Injeções/veterinária , Masculino , Midriáticos/administração & dosagem , Hipertensão Ocular/induzido quimicamente , Hipertensão Ocular/veterinária , Soluções Oftálmicas/administração & dosagem , Complicações Pós-Operatórias/induzido quimicamente , Complicações Pós-Operatórias/veterinária , Estudos Prospectivos , Resultado do Tratamento
5.
Vet Ophthalmol ; 22(5): 591-599, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30706615

RESUMO

OBJECTIVE: To describe the visual outcome following phacoemulsification in English Cocker Spaniels (ECS) affected by cataracts and suspected progressive retinal atrophy (PRA). ANIMALS STUDIED: Fifty-four client-owned dogs. PROCEDURES: A multicenter, retrospective study was performed including ECS with suspected PRA which underwent phacoemulsification. PRA was suspected on ophthalmic examination before and after surgery, and/or after electroretinography (ERG) was performed. Visual outcome was assessed by menace response per eye at seven time periods post-surgery (P1= 25-90 days, P2 = 91-180 days, P3 = 181-364 days, P4 = 365-549 days, P5 = 550-729 days, P6 = 730-1094 days, and P7 ≥ 1095 days). Descriptive statistics were performed. Generalized estimating equations were used to identify predictors associated with vision after surgery. Odds ratio and confidence intervals were reported. Significance was set at P < 0.05. Owners were invited to participate in a questionnaire. RESULTS: Phacoemulsification was performed in 85 eyes. Median age at surgery was 9.09 years (min. 2.17 years, max. 13.49 years). At all re-examinations, up to and including P5, significantly more eyes were visual than before surgery (P ≤ 0.003). Odds for vision were significantly increased for eyes that underwent surgery. Electroretinograms were performed in 75/85 eyes that underwent surgery, demonstrating low b-wave amplitudes. There was no significant effect of the age, gender, vision before surgery, presence of dazzle reflex, cataract stage or abnormality on gonioscopy on visual outcome. The questionnaire response rate was 48.2%. Most participants (92.5%) felt that cataract surgery led to improvement of the dog's quality of life. CONCLUSIONS: English Cocker Spaniels with suspected PRA may benefit from phacoemulsification with vision up to 2 years following surgery.


Assuntos
Doenças do Cão/cirurgia , Facoemulsificação/veterinária , Degeneração Retiniana/veterinária , Animais , Catarata/veterinária , Extração de Catarata/veterinária , Cães , Feminino , Masculino , Degeneração Retiniana/cirurgia , Estudos Retrospectivos , Resultado do Tratamento , Visão Ocular
6.
Vet Ophthalmol ; 22(5): 644-650, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30706667

RESUMO

Cataract removal using phacoemulsification was performed in 10 loggerhead turtles being rehabilitated after stranding. All turtles had significant systemic abnormalities and had cataracts either at the time of rescue or developed them during rehabilitation. Surgical difficulties encountered included an extremely soft globe that did not allow for a partial thickness corneal incision, incomplete topical anesthesia of the ocular surface with proparacaine, inability to dilate the pupil pharmacologically, a markedly shallow anterior chamber, a thick posterior capsular plaque in most cases, and difficulty creating a watertight closure with sutures. Minimal to no intraocular inflammation was seen in all cases following surgery, but all cases in which corneal sutures were used developed a marked inflammatory reaction surrounding the sutures and appeared uncomfortable until sutures were removed or sloughed. All turtles appeared to have improved vision following surgery and were eventually released. Two turtles were re-encountered a year or more after release. Both showed signs of normal growth and the ability to capture prey in the wild. This report documents successful outcomes associated with cataract surgery in loggerhead turtles, but also presents significant surgical challenges that should be taken into account before attempting this procedure in this species.


Assuntos
Extração de Catarata/veterinária , Catarata/veterinária , Facoemulsificação/veterinária , Tartarugas/cirurgia , Animais , Resultado do Tratamento
7.
Vet Ophthalmol ; 22(3): 276-283, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-29975454

RESUMO

OBJECTIVES: To investigate the effects of the intracameral injection of epinephrine and two doses of 2% lidocaine on pupil diameter (PD), intraocular pressure (IOP), heart rate (HR), and mean arterial pressure (MAP) in healthy cats. METHODS: Five treatment groups were formed (10 cats/each). Animals received 0.2 mL of epinephrine, 0.2 or 0.3 mL of 2% lidocaine, or 0.2 mL of BSS. Cats were anesthetized, and all solutions were injected intracamerally. PD, IOP, HR, and MAP were assessed at baseline, following anterior chamber paracentesis (T0), and at every 5 minutes, until anesthesia was terminated (T60). PD and IOP continued to be assessed for 2 additional hours during recovery from anesthesia. In another group, cats were not anesthetized and one of the eyes was treated with one drop of 0.5% tropicamide to check for maximal pupil diameter. RESULTS: Faster onset and longer duration of sufficient mydriasis (>10 mm) were observed in epinephrine treatment group, when comparing with cats treated with both doses of lidocaine. Eyes treated with epinephrine achieved the largest maximum pupil diameter (mm) when comparing with eyes treated with 0.3 mL of lidocaine (11.01 ± 0.16), tropicamide (10.66 ± 0.17), and 0.2 mL of lidocaine (10.23 ± 0.12) (P < .0001). In all groups, IOP decreased significantly at T0, but tended to return to baseline at T60. HR and MAP did not change significantly during time and among treatments. CONCLUSIONS: The intracameral injection of 0.2 mL of 1:100 000 epinephrine and 0.3 mL of 2% lidocaine can be used as an alternative to tropicamide in healthy cats. Both treatments produced satisfactory and long-lasting mydriasis without adverse effects on IOP, HR, and MAP.


Assuntos
Gatos/fisiologia , Epinefrina/farmacologia , Lidocaína/farmacologia , Soluções Oftálmicas/farmacologia , Pupila/efeitos dos fármacos , Animais , Extração de Catarata/veterinária , Combinação de Medicamentos , Epinefrina/administração & dosagem , Feminino , Frequência Cardíaca/efeitos dos fármacos , Injeções/veterinária , Pressão Intraocular/efeitos dos fármacos , Lidocaína/administração & dosagem , Masculino , Soluções Oftálmicas/administração & dosagem , Distribuição Aleatória , Valores de Referência
8.
Vet Ophthalmol ; 22(3): 284-293, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30095212

RESUMO

OBJECTIVES: To describe and compare the cumulative incidence and clinical progression of ocular neuropathies in diabetic dogs vs nondiabetic dogs following cataract surgery. METHODS: Medical records of 196 diabetic and 442 nondiabetic dogs who underwent cataract surgery between 2004 and 2015 were reviewed. The percentage of patients affected by neuropathy and potential risk factors were compared between groups. RESULTS: Patients with diabetes mellitus (DM) were 20.4 times more likely to develop an ocular neuropathy than patients without DM (12.24% vs 0.68%). Twenty-four diabetic patients were affected by mononeuropathies or polyneuropathies including Horner's syndrome (n = 20), facial neuropathy (n = 5), and neurogenic keratoconjunctivitis sicca (NKCS) (n = 5). The odds of a diabetic patient developing Horner's syndrome and NKCS were 86.3 and 20.7 times higher than a nondiabetic patient, respectively. The average duration of DM prior to diagnosis of neuropathy was 659 days (range 110-2390 days; median 559 days). Complete resolution was achieved in 10 of 22 neuropathies (45%) within an average of 248 days (range 21-638 days; median 187 days) after diagnosis. CONCLUSIONS: The odds of developing an ocular neuropathy, specifically Horner's syndrome and NKCS, are statistically higher in diabetic patients compared to nondiabetic patients. Neuropathies were observed as a long-term complication in this group of diabetic patients, and complete resolution of the neuropathy was observed in less than half of the affected population.


Assuntos
Extração de Catarata/veterinária , Diabetes Mellitus Tipo 2/veterinária , Doenças do Cão/epidemiologia , Síndrome de Horner/veterinária , Animais , Doenças do Cão/etiologia , Cães , Feminino , Florida/epidemiologia , Síndrome de Horner/epidemiologia , Incidência , Masculino , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/veterinária , Registros/veterinária
9.
J Appl Anim Welf Sci ; 22(4): 329-341, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30295508

RESUMO

As nonhuman animals age, geriatric individuals require additional care and veterinary support to ensure their well being. The focus on lifelong care is a relatively newer approach when providing good welfare, and few studies have examined how veterinary care impacts behavior at different ages or how best to accommodate geriatric individuals in zoos. The objectives of this study were to (a) assess both the immediate and long-term (one year later) behavioral impacts of cataract removal for macaroni (Eudyptes chrysolophus) and southern rockhopper (Eudyptes chrysocome) penguins; (b) compare the behavior of penguins following cataract surgery to that of other conspecifics in the same habitat; and (c) monitor the impacts of cataract surgery on swimming behavior using time-depth recorders. Individual responses to cataract removal differed in direction and magnitude, and these mixed results highlight that welfare is experienced and thus measured at the individual level. Positive responses included increased habitat use, increased time spent swimming, and increased rates of affiliative interactions. This study highlights the importance of assessing welfare impacts of veterinary interventions on geriatric individuals.


Assuntos
Comportamento Animal , Extração de Catarata/veterinária , Spheniscidae/cirurgia , Bem-Estar do Animal , Animais , Animais de Zoológico/cirurgia , Catarata/veterinária , Feminino , Masculino , Comportamento Social , Natação
10.
Vet Microbiol ; 213: 95-101, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29292010

RESUMO

Bacterial contamination of the anterior chamber during cataract surgery is one of the main responsible for endophthalmitis postoperative. Phacoemulsification is a less invasive technique for cataract treatment, although it does not exclude the possibility of contamination. In this study, bacterial contaminants of aqueous humor collected pre- and post-phacoemulsification with intraocular lens implantation (IOL) of twenty dogs were identified. As the conjunctival microbiota constitute a significant source of anterior chamber contamination, bacterial isolates from aqueous humor were genetically compared with those present in the conjunctival surface of the patients. Three dogs presented bacterial growth in both aqueous humor and conjunctival surface samples. Bacterial isolates from these samples were grouped according to their genetic profiles by repetitive-element PCR (rep-PCR) and their representatives were identified by 16S rRNA sequencing. Isolates from conjunctival surface were identified as Enterobacter spp., Staphylococcus spp. and S. aureus; and from aqueous humor samples as Enterobacter spp., Pantoea spp., Streptococcus spp. and Staphylococcus spp., respectively in decreasing order of prevalence. According to the rep-PCR analysis, 16.6% of Enterobacter spp. isolates from conjunctival surface were genetically similar to those from aqueous humor. The rest of isolates encountered in aqueous humor were genetically distinct from those of conjunctival surface. The significant genetic diversity of bacterial isolates found in the aqueous humor samples after surgery denoted the possibility of anterior chamber contamination during phacoemulsification by bacteria not only from conjunctival surface but also from different sources related to surgical environment.


Assuntos
Humor Aquoso/microbiologia , Bactérias/genética , Endoftalmite/veterinária , Implante de Lente Intraocular/veterinária , Facoemulsificação/veterinária , Animais , Câmara Anterior/microbiologia , Bactérias/isolamento & purificação , Extração de Catarata/veterinária , Túnica Conjuntiva/microbiologia , Cães , Endoftalmite/microbiologia , Endoftalmite/cirurgia
11.
Vet Clin North Am Equine Pract ; 33(3): 483-497, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29103558

RESUMO

Examination of the lens is critical, particularly when evaluating horses with visual impairment or performing prepurchase examinations. To adequately evaluate the lens, the pupil must be pharmacologically dilated. A cataract is any lens opacity. The size, density, and position of a cataract determine the impact on vision. Cataracts may be congenital or inherited or occur secondary to trauma or equine recurrent uveitis. Surgical removal is the only treatment option for vision impairing cataracts, but careful selection of surgical candidates is critical for successful outcomes.


Assuntos
Doenças dos Cavalos/cirurgia , Doenças do Cristalino/veterinária , Animais , Catarata/diagnóstico , Catarata/tratamento farmacológico , Catarata/veterinária , Extração de Catarata/veterinária , Diagnóstico Diferencial , Doenças dos Cavalos/diagnóstico , Doenças dos Cavalos/tratamento farmacológico , Cavalos , Doenças do Cristalino/diagnóstico , Doenças do Cristalino/tratamento farmacológico , Doenças do Cristalino/cirurgia
12.
J Med Primatol ; 46(5): 252-255, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28417453

RESUMO

We report a case of bilateral cataract surgery performed in a 21-year-old western lowland gorilla. Phacoemulsification with intraocular lens insertion was performed using standard human surgical equipment. Visual function significantly improved. She subsequently mated and gave birth. Ultimately, cataract surgery enabled the birth of a baby gorilla.


Assuntos
Animais de Zoológico/cirurgia , Extração de Catarata/veterinária , Gorilla gorilla/cirurgia , Lentes Intraoculares/veterinária , Facoemulsificação/veterinária , Animais , Inglaterra , Feminino , Itália , Resultado do Tratamento
13.
Am J Vet Res ; 78(2): 207-214, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28140645

RESUMO

OBJECTIVE To evaluate changes in conjunctival bacteria and antimicrobial susceptibility of bacteria after cataract surgery in dogs. ANIMALS 16 client-owned dogs. PROCEDURES Samples for aerobic and anaerobic culture were obtained from the conjunctival fornices of both eyes of dogs 24 hours before (week 0) and 1, 3, and 6 weeks after cataract surgery. Topical administration of ofloxacin (every 6 hours) was initiated 12 hours before surgery and continued for 3 weeks. In vitro antimicrobial susceptibility was determined by Kirby-Bauer disk diffusion and a commercially available test for ofloxacin. RESULTS Frequency of positive culture results was significantly higher at week 6 than at weeks 0 and 1. Bacterial load was more likely to be moderate or high at weeks 3 and 6 than at weeks 0 and 1. The most frequently cultured organism was Staphylococcus pseudintermedius (21/78 [26.9%]), followed by coagulase-negative Staphylococcus spp (19/78 [24.4%]). Staphylococcus pseudintermedius was the organism most frequently cultured at weeks 0 (5/12), 1 (4/12), and 6 (8/19), whereas frequency of this organism was lowest at week 3 (1/20). In contrast, coagulase-negative Staphylococcus spp were the most frequently cultured organisms at week 3 (10/20). There was a significant increase in the proportion of organisms resistant to ofloxacin at week 3, compared with the proportion at week 0. CONCLUSIONS AND CLINICAL RELEVANCE The number of bacterial organisms increased and the population of conjunctival bacteria was altered and had a higher proportion resistant to ofloxacin during the 6 weeks after cataract surgery for dogs treated by use of this protocol.


Assuntos
Anti-Infecciosos/uso terapêutico , Extração de Catarata/veterinária , Catarata/veterinária , Doenças do Cão/cirurgia , Ofloxacino/uso terapêutico , Soluções Oftálmicas/uso terapêutico , Animais , Anti-Infecciosos/farmacologia , Túnica Conjuntiva/microbiologia , Cães , Farmacorresistência Bacteriana , Testes de Sensibilidade Microbiana , Ofloxacino/administração & dosagem , Soluções Oftálmicas/farmacologia , Staphylococcus/efeitos dos fármacos
14.
Vet Ophthalmol ; 20(2): 107-113, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26990912

RESUMO

OBJECTIVE: To compare the prevalence and kinetics of ocular hypertension after routine cataract extraction when using a predominately COX-2 inhibitor (bromfenac) versus a predominately COX-1 inhibitor (flurbiprofen) in combination with a topical corticosteroid. PROCEDURES: Patients undergoing unilateral or bilateral cataract surgery were randomly assigned to receive flurbiprofen or bromfenac at the day of surgery and continued for 6 weeks postoperatively, along with topical neo poly dexamethasone. No systemic nonsteroidal anti-inflammatory medications were administered before or after surgery. Intraocular pressure was monitored pre and postoperatively. When an IOP of >25 mmHg was detected, therapeutic intervention was performed. RESULTS: Eyes in both treatment groups showed a similar IOP profile with the highest mean IOP occurring two hours postsurgery and slowly declining during the next 6 weeks. However, eyes receiving bromfenac had a higher mean IOP at 2 h post-op (22.1 mmHg) than eyes receiving flurbiprofen (18.8 mmHg) and a slower decrease in IOP in the weeks after surgery. Over the course of the study, a higher percentage of eyes receiving bromfenac had therapy discontinued over concerns of elevated IOP compared to eyes receiving flurbiprofen (bromfenac 23.1% and flurbiprofen 9.8%). On average, the risk of having elevated intraocular pressure with bromfenac is 1.04 times higher than with flurbiprofen. CONCLUSION: Elevated postoperative IOP was observed in both treatment groups; however, bromfenac-treated eyes were more likely to require intervention for elevated IOP.


Assuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Benzofenonas/efeitos adversos , Bromobenzenos/efeitos adversos , Extração de Catarata/veterinária , Doenças do Cão/tratamento farmacológico , Flurbiprofeno/efeitos adversos , Hipertensão Ocular/etiologia , Complicações Pós-Operatórias/induzido quimicamente , Administração Oftálmica , Animais , Anti-Inflamatórios não Esteroides/administração & dosagem , Benzofenonas/administração & dosagem , Bromobenzenos/administração & dosagem , Extração de Catarata/efeitos adversos , Inibidores de Ciclo-Oxigenase 2/efeitos adversos , Inibidores de Ciclo-Oxigenase/efeitos adversos , Cães , Feminino , Flurbiprofeno/administração & dosagem , Masculino , Hipertensão Ocular/induzido quimicamente , Hipertensão Ocular/epidemiologia , Soluções Oftálmicas/administração & dosagem , Soluções Oftálmicas/efeitos adversos , Prevalência , Estudos Prospectivos
15.
J Am Vet Med Assoc ; 249(9): 1040-1052, 2016 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-27767427

RESUMO

OBJECTIVE To assess the effects of topically applied 2% dorzolamide hydrochloride-0.5% timolol maleate ophthalmic solution (DHTM) on incidence and severity of postoperative ocular hypertension (POH; ie, intraocular pressure [IOP] > 25 mm Hg) in dogs undergoing cataract extraction by phacoemulsification. DESIGN Randomized, masked, controlled study. ANIMALS 103 dogs (180 eyes). PROCEDURES Pertinent history, signalment, and ophthalmic examination findings were recorded. Dogs received 1 drop of DHTM or sham treatment solution (sterile, buffered, isotonic eye drops) in both eyes 14 hours and 2 hours before anesthetic induction and at the time of corneal incision closure (ie, end of surgery); IOPs were assessed by rebound tonometry 2, 4, 6, and 8 hours after surgery and between 7:30 and 8:00 am on the following day. Dogs with IOPs of 26 to 45 mm Hg received 1 drop of 0.005% latanoprost solution topically; the surgeon's treatment of choice was used for dogs with IOPs > 45 mm Hg. Incidence of POH and postoperative IOPs were compared between treatment groups. RESULTS DHTM treatment resulted in significantly lower incidence of POH than did sham treatment at the level of the dog (18/53 [34%] vs 31/50 [62%]) and the eye (24/94 [26%] vs 42/86 [48%]). Mean IOP did not differ between groups at the time of POH detection. The DHTM-treated eyes that developed POH were significantly more likely to have a 1-hour follow-up IOP < 25 mm Hg after latanoprost administration than were sham-treated eyes (19/25 [76%] vs 18/35 [51%]; OR, 3.87). CONCLUSIONS AND CLINICAL RELEVANCE Multidose perioperative administration of DHTM in dogs undergoing phacoemulsification reduced the incidence of POH and improved responsiveness of POH to latanoprost treatment.


Assuntos
Extração de Catarata/veterinária , Doenças do Cão/etiologia , Hipertensão Ocular/veterinária , Complicações Pós-Operatórias/veterinária , Sulfonamidas/farmacologia , Tiofenos/farmacologia , Timolol/farmacologia , Animais , Anti-Hipertensivos/administração & dosagem , Anti-Hipertensivos/farmacologia , Extração de Catarata/efeitos adversos , Doenças do Cão/prevenção & controle , Cães , Combinação de Medicamentos , Hipertensão Ocular/prevenção & controle , Assistência Perioperatória , Complicações Pós-Operatórias/prevenção & controle , Sulfonamidas/administração & dosagem , Tiofenos/administração & dosagem , Timolol/administração & dosagem
16.
Vet Ophthalmol ; 19(3): 184-94, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-25959258

RESUMO

OBJECTIVE: Cataract is the most prevalent cause of blindness in dogs. Phacoemulsification (PE) is currently the surgical treatment of choice to remove the opaque lens; however, it is associated with varying degrees of postoperative inflammation. We assessed the effect of melatonin on postoperative complications of canine cataract surgery. ANIMAL STUDIED: Eleven diabetic and thirteen healthy owned dogs with cataracts. PROCEDURES: All dogs underwent cataract surgery by PE. The anti-inflammatory effect of melatonin was compared with the reference treatments: nonsteroidal anti-inflammatory drugs (NSAIDs) for diabetic dogs, and dexamethasone for nondiabetic dogs. Eyes were examined by means of clinical evaluation and intraocular pressure (IOP). RESULTS: In diabetic dogs, melatonin was more effective than topical and systemic NSAIDs in reducing the clinical score at 2, 7, and 20 days postsurgery, while it showed a similar efficacy to topical dexamethasone in dogs with hereditary cataracts. IOP decreased in all groups at 2 days postsurgery, but this decrease reached statistical significance only in diabetic dogs treated with NSAIDs, and persisted at 7 days postsurgery in this group. Afterward, IOP returned to normal values in all groups. Melatonin decreased the occurrence of surgical sequelae in diabetic and nondiabetic dogs. CONCLUSIONS: These results indicate that melatonin might constitute a useful tool for reducing postoperative PE complications in dogs.


Assuntos
Antioxidantes/uso terapêutico , Extração de Catarata/veterinária , Doenças do Cão/cirurgia , Melatonina/uso terapêutico , Complicações Pós-Operatórias/veterinária , Animais , Doenças do Cão/tratamento farmacológico , Cães , Feminino , Masculino , Complicações Pós-Operatórias/tratamento farmacológico , Resultado do Tratamento
17.
J Zoo Wildl Med ; 46(4): 858-69, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26667543

RESUMO

A review of avian cataracts at the Wildlife Conservation Society's Bronx Zoo between 1992 and 2011 was conducted. Ninety cataracts in 54 birds from 42 species were identified. Cataracts were found primarily during examination for ocular abnormalities (29/54, 53.7%) or opportunistically (13/54, 24.1%) and were most commonly diagnosed as mature (22/90, 24.4%). Systemic medical conditions diagnosed in these birds included West Nile virus (4/54, 7.4%), head trauma (3/54, 5.6%), plumbism and Salmonella Pullorum (1/54, 1.9%), Marek's disease (1/54, 1.9%), leukocytosis (1/54, 1.9%), and hyperglycemia (1/54, 1.9%). Cataracts were progressive in seven birds of four species. Unilateral enucleation was performed in 2/54 (3.7%) birds, and 12/54 (22.2%) underwent cataract removal (phacoemulsification in 16 eyes and standard extracapsular cataract extraction in 2 eyes). Concurrent ocular abnormalities, such as corneal scarring and lens-induced uveitis, were seen in 2/18 (11.1%) eyes preoperatively in the group undergoing cataract removal, 2/2 (100%) eyes preoperatively in the group undergoing enucleation, and 33/70 (47.1%) of eyes that did not undergo surgery. For birds undergoing cataract removal, complications included successfully treated cardiorespiratory arrest intraoperatively (1/12, 8.3%) as well as postanesthetic complications of acute respiratory distress and tracheal stricture (2/12, 16.7%). The most common postoperative ocular abnormalities included posterior capsular opacity (4/18 eyes, 22.2%) and corneal scarring (2/18 eyes, 11.1%). Lens cortical regrowth and marked posterior lens capsular opacity occurred in one eye of one bird after phacoemulsification, necessitating a second ocular surgery. A successful outcome, as determined by improved postoperative visual acuity, was seen in 10/12 (83.3%) birds undergoing cataract removal, and 5/12 (41.7%) of these birds were alive >3 yr after surgery. The results of this review will aid clinicians in identifying common stages of cataracts, determining eligibility for cataract surgery, and managing postoperative complications in avian patients.


Assuntos
Animais de Zoológico , Doenças das Aves/terapia , Extração de Catarata/veterinária , Catarata/veterinária , Animais , Aves , Catarata/diagnóstico , Catarata/patologia , Extração de Catarata/métodos , Estudos Retrospectivos , Especificidade da Espécie
18.
Tierarztl Prax Ausg K Kleintiere Heimtiere ; 42(6): 411-23; quiz 424, 2014.
Artigo em Alemão | MEDLINE | ID: mdl-25422865

RESUMO

Cataract is the leading cause of impaired vision and vision loss in dogs. Because of the considerable progress in cataract surgery in recent decades, lens opacities can now be operated on with very good short-term success (90-95%), taking into account that proper patient selection is essential to maximize the probability of a successful surgical outcome. Following a description of anatomical and physiological lens characteristics, the etiology and complications of untreated cataracts are discussed. Furthermore, specific criteria for patient selection are addressed while delineating essential steps of the examination. This article aims to aid decision making in cataract therapy on the basis of diagnostic guidance and to facilitate the selection of an appropriate point of time for surgery.


Assuntos
Extração de Catarata/veterinária , Doenças do Cão/cirurgia , Animais , Extração de Catarata/métodos , Cães , Glaucoma/veterinária , Guias de Prática Clínica como Assunto , Uveíte/veterinária
19.
Pesqui. vet. bras ; 34(2): 192-198, fev. 2014. ilus
Artigo em Português | LILACS | ID: lil-709865

RESUMO

O exame ultrassonográfico ocular é indispensável no pré-operatório de procedimentos cirúrgicos intraoculares como a facectomia, além de ser uma ferramenta complementar ao exame oftalmológico, em casos de perda da transparência dos meios ópticos. A inexistência de estudos acerca de padrões de normalidades para as medidas do bulbo ocular e de suas estruturas internas nos gatos, cujos valores possibilitam o monitoramento de enfermidades e auxiliam em procedimentos cirúrgicos motivaram este estudo. Utilizaram-se 40 gatos, adultos, machos e fêmeas, livres de enfermidades sistêmica e oftalmológica. Destes, 22 eram da raça persa (grupo braquicefálico - GB) e 18 sem raça definida (grupo não braquicefálico - GNB). A biometria ultrassonográfica ocular transcorneana foi realizada, em modo-B∕A, com o transdutor microlinear de 9 MHz e as medidas D1 (profundidade da câmara anterior), D2 (diâmetro do cristalino), D3 (profundidade da câmara vítrea) e D4 (diâmetro axial do bulbo ocular) aferidas. Ainda, mensuraram-se as distâncias fronto-occipital e bizigomática e o peso desses animais. Os dados obtidos foram analisados pelo teste-t pareado, seguindo-se as análises de variância e covariância, além da regressão linear múltipla relacionando-se as medidas de D1, D2, D3 e D4 às medidas bizigomática e fronto-occipital, como também à idade, ao peso e ao gênero. Obteve-se como resultado a média de D1, D2, D3 e D4, assim como dos diâmetros bizigomático e fronto-occipital, idade e peso, verificando-se diferenças significativas para D4 nas fêmeas de GB. Houve, pela análise de regressão linear, influência do peso, idade e diâmetro fronto-occipital sobre D1, D2 e D4 nos gatos do GB, e dos diâmetros bizigomático sobre D1, D3 e D4 nos gatos do GNB. Conclui-se que houve diferença no diâmetro axial do bulbo ocular nas fêmeas do GB, e que o peso, a idade e os diâmetros cranianos influenciam a biometria ocular dos gatos braquicefálicos e não braquicefálicos.


Ocular ultrasonography is a helpful ophthalmic examination, performed on the absence of transparency in ocular means and frequently requested prior intraocular surgery. Unfortunately, the lack of studies upon ultrasonografic images of the normal feline eye, difficults the evaluation of its biometry and its inner structures in many ophthalmic diseases and also before surgery. The objective of this study was to evaluate the ocular biometry and the morphometric parameters of the cranium of 40 healthy adult cats, including 22 Persian cats (Brachycephalic group - BG) and 18 Mixed-breed cats (Noun brachycephalic group - NBG). B/A-mode ultrasonographic biometry, utilizing a 9 MHz probe, was performed for depth of the anterior chamber (D1), lens axial length (D2), depth of the vitreous chamber (D3) and axial length of the globe (D4). Morphometric parameters of the cranium were obtained for bizygomatic (BZ) and occipital frontal (OF) diameters. Data was collected and statistical analysis, including "t" paired tests, variance and covariance analysis and multiple linear regressions was performed for every obtained measure and also for animal ages, weigh and gender. Statistic relevant values were observed in D4 parameter for female cats of BG. Multiple linear regression indicated some influence of the weigh, age and OF in D1, D2 and D4 of PG; and of BZ in D1, D3 and D4 of NBG. Besides that, it was observed that biometry was also influenced by weigh, age and morphometric parameters of their craniums in both groups.


Assuntos
Animais , Gatos , Biometria , Crânio/anatomia & histologia , Gatos/anatomia & histologia , Olho/anatomia & histologia , Padrões de Referência , Ultrassonografia/veterinária , Cuidados Pré-Operatórios/veterinária , Extração de Catarata/veterinária , Fenômenos Fisiológicos Oculares
20.
J Fr Ophtalmol ; 36(8): 645-51, 2013 Oct.
Artigo em Francês | MEDLINE | ID: mdl-23684994

RESUMO

OBJECTIVE: To describe postoperative complications and visual outcomes after immediately sequential bilateral cataract surgery (ISBCS) and to assess whether additional risk is incurred by operating on the fellow eye immediately following the first. ANIMALS STUDIED: A retrospective review of 128 dogs (256 eyes) that underwent ISBCS in three veterinary ophthalmology centers between May 2007 and December 2011 was performed. PROCEDURE: Visual status at final evaluation was recorded and intra- and postoperative complications were recorded and analyzed. Data for the first operated eye (FE) and then the second eye (SE) were statistically analyzed to assess whether performing surgery on the SE immediately after the FE resulted in any negative consequences for the second eye. RESULTS: No serious intraoperative anesthetic incident occurred due to prolonged surgery. Phacoemulsification times were significantly shorter for the SE than for the FE. On final examination, 239 eyes out of 256 (93.36%) exhibited functional vision (score 2), and three dogs were completely blind due to long-term bilateral postoperative complications. The most common postoperative complications were uveitis (58 eyes, 22.66%), postoperative ocular hypertension (POH; nine eyes, 3.5%), glaucoma (nine eyes, 3.5%) and total retinal detachment (seven eyes, 2.73%). No case of endophthalmitis was reported. These results were no worse than those typically reported for unilateral phacoemulsification. In addition, the risk of blindness and other postoperative complications was not significantly increased in the SE. CONCLUSIONS: The results of this study suggest that ISBCS is not associated with an increased incidence of intra- or postoperative complications compared to classic unilateral cataract surgery and might be a viable option for selected patients. The risk of blindness or postoperative complications was not higher in SEs than in FEs.


Assuntos
Extração de Catarata/métodos , Extração de Catarata/veterinária , Animais , Cegueira/etiologia , Cegueira/cirurgia , Cegueira/veterinária , Catarata/complicações , Catarata/veterinária , Extração de Catarata/efeitos adversos , Extração de Catarata/estatística & dados numéricos , Cães , Complicações Intraoperatórias/epidemiologia , Facoemulsificação/efeitos adversos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Acuidade Visual/fisiologia
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